This anti-aging serum is formulated around Palmitoyl Tripeptide-1 and Palmitoyl Hexapeptide-12 to soften the look of wrinkles.
This anti-aging serum is formulated around Lactococcus Ferment Lysate and Acetyl Hexapeptide-8 to soften the look of wrinkles and hydrate skin.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Cyclopentasiloxane
Emollient
Dimethicone Crosspolymer
Emulsion Stabilising
Pentaerythrityl Tetraisostearate
Emollient
Heptyl Undecylenate
EmollientGlycine Soja Oil
Emollient
Panthenyl Triacetate
Palmitoyl Tripeptide-1
Skin Conditioning
Palmitoyl Hexapeptide-12
Skin Conditioning
Naringenin
Skin ConditioningOleuropein
Antioxidant
Olea Europaea Leaf Extract
Perfuming
Phosphatidylserine
Emulsion StabilisingArnica Montana Extract
Skin ConditioningPhospholipids
Skin Conditioning
Dunaliella Salina Extract
Skin ConditioningTocopherol
Antioxidant
Ascorbyl Palmitate
Antioxidant
Squalane
Emollient
Caprylic/Capric Triglyceride
Masking
Caprylyl Methicone
Skin Conditioning
Propylene Carbonate
SolventStearalkonium Hectorite
Gel FormingCyclopentasiloxane, Dimethicone Crosspolymer, Pentaerythrityl Tetraisostearate, Heptyl Undecylenate, Glycine Soja Oil, Panthenyl Triacetate, Palmitoyl Tripeptide-1, Palmitoyl Hexapeptide-12, Naringenin, Oleuropein, Olea Europaea Leaf Extract, Phosphatidylserine, Arnica Montana Extract, Phospholipids, Dunaliella Salina Extract, Tocopherol, Ascorbyl Palmitate, Squalane, Caprylic/Capric Triglyceride, Caprylyl Methicone, Propylene Carbonate, Stearalkonium Hectorite
Water
Skin ConditioningGlycerin
Humectant
Lactococcus Ferment Lysate
Skin Conditioning
Acetyl Hexapeptide-8
Humectant
Pentapeptide-18
Skin Conditioning
Palmitoyl Tripeptide-1
Skin Conditioning
Palmitoyl Tetrapeptide-7
Skin Conditioning
Palmitoyl Tripeptide-38
Skin Conditioning
Dipeptide Diaminobutyroyl Benzylamide Diacetate
Skin Conditioning
Acetylarginyltryptophyl Diphenylglycine
Skin ConditioningSodium Hyaluronate Crosspolymer
Humectant
Sodium Hyaluronate
Humectant
Allantoin
Skin Conditioning
Glycine
Buffering
Alanine
Masking
Serine
Masking
Valine
MaskingIsoleucine
Skin ConditioningProline
Skin Conditioning
Threonine
Histidine
Humectant
Phenylalanine
Masking
Arginine
Masking
Aspartic Acid
Masking
Trehalose
Humectant
Fructose
Humectant
Glucose
Humectant
Maltose
MaskingUrea
Buffering
Sodium PCA
Humectant
PCA
Humectant
Sodium Lactate
Buffering
Citric Acid
Buffering
Hydroxypropyl Cyclodextrin
MaskingSodium Chloride
MaskingSodium Hydroxide
BufferingButylene Glycol
Humectant
Pentylene Glycol
Skin Conditioning
Acacia Senegal Gum
MaskingXanthan Gum
EmulsifyingCarbomer
Emulsion StabilisingPolysorbate 20
Emulsifying
PPG-26-Buteth-26
Skin ConditioningPEG-40 Hydrogenated Castor Oil
Emulsifying
Trisodium Ethylenediamine Disuccinate
Ethoxydiglycol
HumectantSodium Benzoate
Masking
Caprylyl Glycol
Emollient
Ethylhexylglycerin
Skin ConditioningPhenoxyethanol
Preservative
Chlorphenesin
Antimicrobial
Water, Glycerin, Lactococcus Ferment Lysate, Acetyl Hexapeptide-8, Pentapeptide-18, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-38, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Acetylarginyltryptophyl Diphenylglycine, Sodium Hyaluronate Crosspolymer, Sodium Hyaluronate, Allantoin, Glycine, Alanine, Serine, Valine, Isoleucine, Proline, Threonine, Histidine, Phenylalanine, Arginine, Aspartic Acid, Trehalose, Fructose, Glucose, Maltose, Urea, Sodium PCA, PCA, Sodium Lactate, Citric Acid, Hydroxypropyl Cyclodextrin, Sodium Chloride, Sodium Hydroxide, Butylene Glycol, Pentylene Glycol, Acacia Senegal Gum, Xanthan Gum, Carbomer, Polysorbate 20, PPG-26-Buteth-26, PEG-40 Hydrogenated Castor Oil, Trisodium Ethylenediamine Disuccinate, Ethoxydiglycol, Sodium Benzoate, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol, Chlorphenesin
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Palmitoyl Tripeptide-1 (aka Pal-GHK) is a synthetic signal peptide made of three amino acids attached to palmitic acid.
That fatty acid attachment is the key: it boosts the peptide's ability to penetrate the skin barrier. This puts it closer to the dermal cells where it can actually make a difference.
Once there, it acts as a matrikine, a signaling peptide that prompts fibroblasts to produce more collagen, fibronectin, and hyaluronic acid.
In vitro studies show it can boost collagen production in skin cells even when UV-damaged skin samples were treated with it at a tiny concentration (it almost fully restored dermal collagen at 5ppm). It achieved this at 100x lower concentration than retinoic acid, which needed 500 ppm to do the same thing.
Human clinical data is promising, but modest:
A study of 23 female volunteers found a small but statistically significant increase (~4%) in skin thickness after treatment at 4 ppm.
A separate small trial of 15 women showed statistically significant reductions in wrinkle length, depth, and skin roughness after applying it twice daily for four weeks.
You'll likely see Pal-GHK paired with Palmitoyl Tetrapeptide-7 as part of the Matrixyl 3000 complex.
Fungal acne note:
Usually a palmitic acid component can feed Malassezia in unbound form, but here is is covalently bonded to the peptide. This means it is very difficult for Malassezia to access, and therefore very unlikely to cause fungal acne.
