Synergie Skin Super Serum+
A serum with 35 ingredients, including hyaluronic acid and peptides.
This anti-aging serum is formulated around Acetyl Octapeptide-3 to soften the look of wrinkles.
Worth noting
Contains EU-listed fragrance allergens, including Citrus Aurantium Flower Oil and Limonene.
We independently verify ingredients, backed by peer-reviewed research. Suggest an update.
What's inside
Ingredients List
Water
Skin ConditioningGlycerin
HumectantMethylpropanediol
SolventHydrolyzed Tomato Skin
Skin ConditioningBetaine
HumectantDimethyl Isosorbide
SolventButylene Glycol
HumectantSodium PCA
HumectantPolyglyceryl-6 Caprylate
EmulsifyingPolyglyceryl-4 Caprate
EmulsifyingCaprylyl Glycol
EmollientAloe Barbadensis Leaf Juice
Skin ConditioningMaltodextrin
AbsorbentPropanediol
SolventHydrolyzed Algin
Phenylpropanol
MaskingCitrus Aurantium Flower Oil
PerfumingSodium Hyaluronate
HumectantSphingomonas Ferment Extract
Skin ConditioningOriganum Majorana Leaf Extract
AntiseborrhoeicSodium Lactate
BufferingPentylene Glycol
Skin ConditioningCitric Acid
BufferingSaccharide Isomerate
HumectantSodium Benzoate
MaskingLevulinic Acid
PerfumingAcetyl Octapeptide-3
HumectantPotassium Sorbate
PreservativeSodium Levulinate
Skin ConditioningAcetyl Hexapeptide-51 Amide
Skin ConditioningLactic Acid
BufferingSodium Hydroxide
BufferingLimonene
PerfumingGeraniol
PerfumingLinalool
PerfumingWater, Glycerin, Methylpropanediol, Hydrolyzed Tomato Skin, Betaine, Dimethyl Isosorbide, Butylene Glycol, Sodium PCA, Polyglyceryl-6 Caprylate, Polyglyceryl-4 Caprate, Caprylyl Glycol, Aloe Barbadensis Leaf Juice, Maltodextrin, Propanediol, Hydrolyzed Algin, Phenylpropanol, Citrus Aurantium Flower Oil, Sodium Hyaluronate, Sphingomonas Ferment Extract, Origanum Majorana Leaf Extract, Sodium Lactate, Pentylene Glycol, Citric Acid, Saccharide Isomerate, Sodium Benzoate, Levulinic Acid, Acetyl Octapeptide-3, Potassium Sorbate, Sodium Levulinate, Acetyl Hexapeptide-51 Amide, Lactic Acid, Sodium Hydroxide, Limonene, Geraniol, Linalool
Key Ingredients
Benefits
Concerns
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinMethylpropanediol is a synthetic solvent and humectant.
As a solvent, it helps dissolve other ingredients, helping to evenly distribute ingredients throughout the product. This ingredient has also been shown to have antimicrobial properties which makes it a preservative booster.
Methylpropanediol is able to add a bit of moisture to the skin. It also helps other ingredients be better absorbed into the skin, such as salicylic acid.
Learn more about MethylpropanediolWe don't have a description for Hydrolyzed Tomato Skin yet.
Betaine is a humectant. Like hyaluronic acid, it helps attract and retain moisture in the skin. It’s known for being gentle and for helping the skin maintain balanced hydration.
Betaine is mainly used to improve hydration and support calmer skin. It helps skin cells regulate water balance because it functions as an osmolyte.
Some studies suggest betaine may support making skin tone more even.
Fun fact: Betaine naturally exists in the skin and the body. In cosmetic products, it can be either plant-derived (most commonly from sugar beets) or synthetically produced for consistency and stability.
Betaine is also known as trimethylglycine.
Learn more about BetaineDimethyl Isosorbide (often shortened to DMI) is a sugar-derived solvent made from sorbitol. It's used to dissolve tricky ingredients and help them mix smoothly into a formula.
Many actives sit as gritty crystals when undissolved, so DMI swoops in to full dissolve them. This helps improve texture, stability, and how evenly an active is distributed.
It does have a penetration-enhancing reputation that is a bit more nuanced than marketing suggests; a cell study on human skin found that 10% DMI didn't significantly boost the permeation of Hydroquinone, Salicylic Acid, or Octadecenedioic Acid compared to controls (though it did improve their solubility in the formula itself).
Typical usage concentrations usually range from 1-10% depending on the formula's needs; this ingredient is also well tolerated at these levels.
Learn more about Dimethyl IsosorbideButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolSodium PCA is the sodium salt of pyroglutamic acid. It is naturally occurring in our skin's natural moisturizing factors where it works to maintain hydration.
The PCA stands for pyrrolidone carboxylic acid, a natural amino acid derivative.
This ingredient has skin conditioning, anti-inflammatory, and humectant properties. Humectants help hydrate your skin by drawing moisture from the air. This helps keep your skin moisturized.
Learn more about Sodium PCAPolyglyceryl-6 Caprylate comes from caprylic acid and Polyglycerin-6. It is an emulsifier, emollient, and cleansing agent.
Emulsifiers help stabilize a product. It does this by preventing certain ingredients from separating. Common ingredients include oils and water, which do not mix naturally. Emulsifiers have properties that help keep ingredients such as these together. There is emerging research that shows emulsifiers may also help in delivering ingredients into the skin.
As an emollient, polyglyceryl-6 caprylate helps soften skin.
Learn more about Polyglyceryl-6 CaprylatePolyglyceryl-4 Caprate comes from Capric Acid and Polyglycerin-4. It is an emulsifier.
Emulsifiers help stabilize a product. They do this by preventing ingredients from separating, such as oils and water which do not mix naturally.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Learn more about Caprylyl GlycolAloe Barbadensis Leaf Juice comes from leaves of the aloe plant. Aloe Barbadensis Leaf Juice is best known for helping to soothe sunburns. It is also anti-inflammatory, moisturizing, antiseptic, and can help heal wounds.
Aloe is packed with good stuff including Vitamins A, C, and E. These vitamins are antioxidants, which help fight free-radicals and the damage they may cause. Free-radicals are molecules that may damage your skin cells, such as pollution.
Aloe Barbadensis Leaf Juice also contains sugars. These sugars come in the form of monosaccharides and polysaccharides, folic acid, and choline. These sugars are able to help bind moisture to skin.
It also contains minerals such as calcium, 12 anthraquinones, fatty acids, amino acids, and Vitamin B12.
Learn more about Aloe Barbadensis Leaf JuiceMaltodextrin is a plant-derived carbohydrate made by breaking down starch (usually from corn, potato, or rice). In cosmetic formulas, it's a multitasking absorbent, emulsion stabilizer, and skin conditioner.
This ingredient is mostly used to stabilize emulsions and improve the powdery, non-greasy feel of products (like dry shampoos).
Safety-wise, this ingredient is pretty solid; it's even recognized as a food additive. Both animal and clinical studies found no adverse effects at the levels used in cosmetics.
Industry data shows this ingredient is used up to 45.7% in spray products and up to 33% in powder products.
Learn more about MaltodextrinPropanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Learn more about PropanediolThis ingredient is made from brown seaweed and is often used to improve the texture of products.
According to a manufacturer, this is a lightweight ingredient and a smaller form of algin. This allows it to be easily mixed with water and improve the spreadability of products.
It also has conditioning properties that mostly sits on the surface of skin as an emollient. Some lab research has explored it in anti-aging formulas, but the results were modest.
Learn more about Hydrolyzed AlginPhenylpropanol is a fragrance.
Citrus Aurantium Flower Oil is a fragrance and is an oil. It can cause irritation.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Learn more about Sodium HyaluronateThis ingredient is created by the fermentation of Sphingomonas, an interesting bacteria. Sphingomonas bacteria use ubiquinone-10 to help them breathe and their cell walls contain ceramides.
Early research suggests that certain skin bacteria, especially Sphingomonas, could play a helpful role in skin health.
In small studies, these bacteria seemed to become more common after regular sun exposure, with one strain showing the ability to resist UV light and reduce stress in skin cells. Another study also linked Sphingomonas to smoother and more supple skin.
While these results sound promising, the research is still in its early stages, and more studies are needed to know how reliable or meaningful these effects really are.
Fun fact: Unlike most microbes, Sphingomonas can survive the wine fermentation process, making it a tiny microbial marker of a wine's unique "terroir", or the environment’s “fingerprint” on the wine.
Like other ferments, this ingredient may not be Malassezia folliculitis safe.
Learn more about Sphingomonas Ferment ExtractWe don't have a description for Origanum Majorana Leaf Extract yet.
Sodium Lactate is the sodium salt of lactic acid, an AHA. It is a humectant and sometimes used to adjust the pH of a product.
This ingredient is part of our skin's NMF, or natural moisturizing factor. Our NMF is essential for the hydration of our top skin layers and plasticity of skin. NMF also influences our skin's natural acid mantle and pH, which protects our skin from harmful bacteria.
High percentages of Sodium Lactate can have an exfoliating effect.
Fun fact: Sodium Lactate is produced from fermented sugar.
Learn more about Sodium LactatePentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:
Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.
On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.
Typical use levels in a formula run about 1-5%.
Learn more about Pentylene GlycolCitric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
In skincare formulas, citric acid can:
While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
Read more about some other popular AHA's here:
Learn more about Citric AcidSaccharide Isomerate comes from sugars found in corn. It is a skin hydrator.
The structure of this ingredient can be altered to be more similar to the carbohydrates found in our skin. This ability to mimic our skin gives it hydrating properties.
Specifically, saccharide Isomerate is a humectant. Humectants draw moisture from the air to our skin.
Research shows Saccharide Isomerate to be an effective moisturizer.
Learn more about Saccharide IsomerateSodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.
Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.
Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.
It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.
Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.
We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.
Learn more about Sodium BenzoateLevulinic Acid is a fragrance that comes from the degradation of cellulose. It is a saturated fatty acid.
This ingredient is often used a building block for other compounds, such as in pharmaceuticals.
According to a manufacturer, this ingredient smells like caramel.
Learn more about Levulinic AcidAcetyl Octapeptide-3 is a synthetic peptide also commonly known as SNAP-8. It is a lab-made peptide often marketed as a gentler, topical alternative to Botox.
It works by mimicking part of a protein involved in muscle contractions, which may help relax facial tension and reduce the appearance of fine lines (mostly around the eyes and forehead).
It’s considered a “next-gen” version of Argireline (Acetyl Hexapeptide-8), an older peptide with more research behind it that also supports collagen production.
SNAP-8 showed slightly better results than Argireline in one small manufacturer-funded study, but there’s limited independent research. Plus, most tests use concentrations higher than what’s typically found in skincare products.
This ingredient might offer a subtle smoothing effect but it won't don’t deliver the dramatic results of actual Botox injections.
Think of it more like a supporting actor in your skincare lineup.
Learn more about Acetyl Octapeptide-3Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.
This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.
Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.
You'll often find this ingredient used with other preservatives.
Learn more about Potassium SorbateSodium levulinate is the a sodium salt of Levulinic Acid. Oncedissolved in an aqueous solution, the two ingredients become identical. It is usually derived from renewable plant sources like corn starch or sugarcane.
In skincare, it mostly acts as a skin conditioning agent that keeps skin soft and hydrated. It also acts as a preservative booster by inhibiting the growth of mold, yeast, and bacteria.
It's often paired with Sodium Anisate as the two create a broad-spectrum preservative system that is popular in "natural" formulations.
This ingredient is water-soluble.
The CIR Expert Panel for Cosmetic Ingredient Safety has concluded this ingredient to be non-irritated and there are no restrictions for use in EU cosmetics. The FDA also allows this ingredient to be used as a food-grade flavoring agent.
Learn more about Sodium LevulinateAcetyl Hexapeptide-51 Amide is a peptide.
Lactic Acid is another well-loved alpha hydroxy acid (AHA). It is gentler than glycolic acid but still highly effective.
Its main role is to exfoliate the surface of the skin by loosening the “glue” that holds dead skin cells together. Shedding those old cells leads to smoother, softer, and more even-toned skin.
Because lactic acid molecules are larger than glycolic acid, they don’t penetrate as deeply. This means they’re less likely to sting or irritate, making it a great choice for beginners or those with sensitive skin.
Like glycolic acid, it can:
Lactic acid also acts as a humectant (like hyaluronic acid). It can draw water into the skin to improve hydration and also plays a role in the skin's natural moisturizing factor (NMF) in the form of sodium lactate.
Studies show it can boost ceramide production to strengthen the skin barrier and even help balance the skin’s microbiome.
To get results, choose products with a pH between 3-4.
Lower strengths (5-12%) focus on surface exfoliation; higher strengths (12% and up) can reach deeper in the dermis (deeper, supportive layer) to improve skin texture and firmness over time.
Though it was originally derived from milk, most modern lactic acid used in skincare is vegan. It is made through non-dairy fermentation to create a bio-identical and stable form suitable for all formulations.
When lactic acid shows up near the end of an ingredient list, it usually means the brand added just a tiny amount to adjust the product’s pH.
Legend has it that Cleopatra used to bathe in sour milk to help reduce wrinkles.
Lactic acid is truly a gentle multitasker: it exfoliates, hydrates, strengthens, and brightens. It's a great ingredient for giving your skin a smooth, glowing, and healthy look without the harshness of stronger acids.
Read more about some other popular AHA's here:
Learn more about Lactic AcidSodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Learn more about Sodium HydroxideLimonene is a fragrance that adds scent and taste to a formulation.
It's found in the peel oil of citrus fruits and other plants such as lavender and eucalyptus. The scent of limonene is generally described as "sweet citrus".
Limonene acts as an antioxidant, meaning it helps neutralize free radicals.
When exposed to air, oxidized limonene may sensitize the skin. Because of this, limonene is often avoided by people with sensitive skin.
The term 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term. For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance.
Learn more about LimoneneGeraniol is used to add fragrance/parfum to a product. It is the main component of citronellol. It is a monoterpenoid and an alcohol.
Monoterpenes are naturally found in many parts of different plants.
Geraniol can be found in many essential oils including Rose Oil and Citronella Oil. The scent of Geraniol is often described as "rose-like". Many foods also contain Geraniol for fruit flavoring.
Geraniol can irritate the skin when exposed to air. However, irritation depends on the ability of geraniol to penetrate into the skin. In general, geraniol is not able to penetrate skin easily.
Geraniol is colorless and has low water-solubility. However, it is soluble in common organic solvents.
Like citronellol, it is a natural insect repellent.
2,6-Octadien-1-ol, 3,7-dimethyl-, (2E)-
Learn more about GeraniolLinalool is a fragrance and helps add scent to products. It's derived from common plants such as cinnamon, mint, citrus, and lavender.
Like Limonene, this ingredient oxidizes when exposed to air. Oxidized linalool can cause allergies and skin sensitivity.
This ingredient has a scent that is floral, spicy tropical, and citrus-like.
Learn more about LinaloolReviews
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Where it's from
Synergie Skin is a Australian brand
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Read more about us· Updated September 7, 2025 • Added by Claudzi