Sola Beauty Glow Guard Sunscreen Stick SPF 50+
A sunscreen with 38 ingredients, including spf, exfoliants, and peptides.
This chemical sunscreen covers the full UV range and blocks ~98% of UVB at SPF 50.
Worth noting
Contains EU-listed fragrance allergens, including Hexyl Cinnamal and Linalool.
We independently verify ingredients, backed by peer-reviewed research. Suggest an update.
What's inside
Ingredients List
Cyclopentasiloxane
EmollientCetyl Ethylhexanoate
EmollientCeresin
Emulsion StabilisingOctocrylene
UV AbsorberEthylhexyl Methoxycinnamate
UV AbsorberSilica
AbrasiveMethyl Methacrylate/Glycol Dimethacrylate Crosspolymer
Polyethylene
AbrasiveEthylhexyl Salicylate
UV AbsorberDiethylamino Hydroxybenzoyl Hexyl Benzoate
UV FilterBis-Ethylhexyloxyphenol Methoxyphenyl Triazine
Skin ConditioningVinyl Dimethicone/Methicone Silsesquioxane Crosspolymer
Copernicia Cerifera Wax
Ozokerite
Emulsion StabilisingMicrocrystalline Wax
Emulsion StabilisingSorbitan Sesquioleate
EmulsifyingBisabolol
AntioxidantSorbitan Olivate
EmulsifyingParfum
MaskingHexyl Cinnamal
PerfumingLinalool
PerfumingLimonene
PerfumingGeraniol
PerfumingCitronellol
PerfumingWater
Skin ConditioningButylene Glycol
HumectantGlycerin
HumectantPolyglyceryl-10 Laurate
Skin Conditioning1,2-Hexanediol
Skin ConditioningCaprylyl Glycol
EmollientPanax Ginseng Root Extract
EmollientIllicium Verum Fruit Extract
PerfumingCopper Tripeptide-1
Skin ConditioningPalmitoyl Pentapeptide-4
Skin ConditioningTripeptide-1
Skin ConditioningPalmitoyl Tripeptide-1
Skin ConditioningHexapeptide-9
Skin ConditioningHexapeptide-11
Skin ConditioningCyclopentasiloxane, Cetyl Ethylhexanoate, Ceresin, Octocrylene, Ethylhexyl Methoxycinnamate, Silica, Methyl Methacrylate/Glycol Dimethacrylate Crosspolymer, Polyethylene, Ethylhexyl Salicylate, Diethylamino Hydroxybenzoyl Hexyl Benzoate, Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, Vinyl Dimethicone/Methicone Silsesquioxane Crosspolymer, Copernicia Cerifera Wax, Ozokerite, Microcrystalline Wax, Sorbitan Sesquioleate, Bisabolol, Sorbitan Olivate, Parfum, Hexyl Cinnamal, Linalool, Limonene, Geraniol, Citronellol, Water, Butylene Glycol, Glycerin, Polyglyceryl-10 Laurate, 1,2-Hexanediol, Caprylyl Glycol, Panax Ginseng Root Extract, Illicium Verum Fruit Extract, Copper Tripeptide-1, Palmitoyl Pentapeptide-4, Tripeptide-1, Palmitoyl Tripeptide-1, Hexapeptide-9, Hexapeptide-11
Key Ingredients
Benefits
Concerns
Ingredients Explained
Cyclopentasiloxane (D5) is a lightweight silicone that mostly acts as an emollient and solvent in cosmetics. Its the reason your products feel silky, fast-spreading, and non-greasy.
Since D5 is volatile, it does its thing and then evaporates off the skin quickly.
The safety profile of this ingredient is reassuring; the US CIR Expert Panel concluded D5 is safe as used in cosmetics and Health Canada concluded that D5 is not harmful to human health or the environment as currently used in cosmetics
There's a study that people mention about D5 in a rat study showing tumors. This study is related to long-term inhalation of high D5 levels.
Regulatory bodies have judged this study to be not applicable in topical skincare since skin absorption of D5 is very low and we're not really inhaling huge amounts of D5.
The only restriction for this ingredient is environmental. The European Chemicals Agency (ECHA) restricted D5 in wash-off cosmetics at or above 0.1% due to their persistence in water.
Learn more about CyclopentasiloxaneCetyl Ethylhexanoate is an emollient ester. It comes from cetearyl alcohol and 2-ethylhexanoic acid.
Cetyl Ethylhexanoate is an emollient that adds a velvety feel to skin without being greasy or oily. Emollients help trap moisture into your skin, keeping your skin soft and hydrated.
Ceresin is a wax derived from ozokerite. It is an alternative to beeswax.
The most common process of creating ceresin is by using heat and sulfuric acid.
Octocrylene is an oil-soluble organic UV filter that mainly absorbs UVB and short wave UVA II light.
Its real superpower is teamwork: octocrylene is remarkably photostable and is most famous for stabilizing avobenzone (the workhorse UVA filter).
This ingredient is commonly used to enhance both UVB and UVA protection due to its unique property in stabilizing avobenzone. It also pulls double duty by boosting water resistance and giving formulas a smooth, spreadable feel.
The EU's Scientific Committee on Consumer Safety (SCCS) has deemed octocrylene to be safe as a UV-filter at concentrations up to 10% (capped at 9% in propellant sprays). The US also permits it up to 10%.
Two things worth knowing:
You'll usually see this ingredient used in concentrations between 2-10% (higher amounts when used as a stabilizer for avobenzone).
Learn more about OctocryleneThis ingredient is also known as Octinoxate and is one of the oldest and most widely used chemical UV filters in skincare.
It has a simple job: soap up UVB radiation (290-320 nm), the wavelengths responsible for sunburn and a big chunk of long-term sun damage.
In formulas, it's always paired with a separate UVA filter because octinoxate solely protects skin from UVB.
Because it's an oil-soluble liquid, it's easy to blend into the oil phase of lotions/creams and gives a cosmetically elegant feel.
The one quirk about formulating this ingredient is photostability; the molecule slowly changes shape into a less effective version when sunlight hits it. So the longer you're in the sun, the weaker its protection gets. The drop can be more than 30% in some formulas.
It also doesn't play nice with Avobenzone (the common UVA filter) since avobenzone destabilizes octinoxate and the two degrade each other. But don't worry: brands have solved this issue by adding photostabilizers like Tinosorb S to prevent degradation and keep SPF stable under heavy UV exposure.
The maximum allowed level is 10% in the EU and Australia, 7.5% in the US and Canada, and 20% in Japan.
The Cosmetic Ingredient Review Panel has concluded this ingredient to be safe in cosmetics up to 10%.
One last thing worth knowing for context:
Octinoxate has been the subject of ongoing review in Europe where the Scientific Committee on Consumer Safety's (SCCS) 2025 final opinion is that this ingredient is an endocrine-active substance.
Lab and animal studies suggest it can act a bit like a hormone in the body (mildly mimicking estrogen and slightly blocking male hormones). It's important to know this hasn't really been shown to happen in everyday human use.
This ingredient is also banned in Hawaii over coral reef concerns.
Learn more about Ethylhexyl MethoxycinnamateSilica, also known as silicon dioxide, is a naturally occurring mineral. It is used as a fine, spherical, and porous powder in cosmetics.
Though it has exfoliant properties, the function of silica varies depending on the product.
The unique structure of silica enhances the spreadability and adds smoothness, making it a great texture enhancer.
It is also used as an active carrier, emulsifier, and mattifier due to its ability to absorb excess oil.
In some products, tiny microneedles called spicules are made from silica or hydrolyzed sponge. When you rub them in, they lightly polish away dead skin layers and enhance the penetration of active ingredients.
Learn more about SilicaWe don't have a description for Methyl Methacrylate/Glycol Dimethacrylate Crosspolymer yet.
Polyethylene is a synthetic ingredient that helps the skin retain moisture. It is a polymer.
It is also typically used within product formulations to help bind solid ingredients together and thicken oil-based ingredients. When added to balms and emulsions, it helps increase the melting point temperature.
Ethylhexyl Salicylate (also called Octisalate or Octyl Salicylate) is an oil-soluble organic UV filter that's been used in sunscreen since the 1950's.
It absorbs UVB light in the 280-320 nm range with a peak absorbance around 306 nm.
You'll often see it paired with other UV filters to boost overall SPF because octisalate is a fairly week filter on its own.
The reason you'll see it so often is because it can help solubilize and stabilize the trickier filters like oxybenzone and avobenzone.
Unlike these filters, octisalate has pretty good photostability and doesn't create skin-damaging free radicals when exposed to sunlight.
The fatty-alcohol part of the molecule also gives it a light, emollient feel so it doubles as a nice texture enhancer.
Usage levels vary around the world:
Safety-wise, this ingredient has a pretty reassuring track record. The EU's Scientific Committee on Consumer Products (SCCP) found very low skin penetration in human skin tests and negative results for irritation, phototoxicity, and photoallergy.
The real-world allergy risk is pretty low too; a 2012 European study of 1,031 people recorded only 2 reactions to it (a rate of 0.19%).
You might have seen scary headlines about sunscreen getting into your blood.
In 2019, the FDA found that several chemical filters can absorb through the skin and show up in the bloodstream at small but measurable levels.
Here's the important part: these tiny levels are just a cutoff the FDA uses to decide which ingredients need more testing and doesn't mean anything harmful was found.
The researchers were clear that the results are no reason to stop wearing sunscreen.
Learn more about Ethylhexyl SalicylateDiethylamino Hydroxybenzoyl Hexyl Benzoate (DHHB) is a chemical UV-A absorber. It is formulated for high UVA protection (320-400 nm).
DHHB is well-liked for:
DHHB has been approved by the EU, Japan, Taiwan, and South America for use up to 10%. Unfortunately, it has not been approved for use in the US or Canada due to slow regulatory processes.
This ingredient is soluble in oils, fats, and lipids.
Learn more about Diethylamino Hydroxybenzoyl Hexyl BenzoateThis ingredient is better known as bemotrizinol or Tinosorb S and is one of the best broad-spectrum UV filters in modern sunscreen.
It works by absorbing UV light across a whole range (280-400 nm) with peaks around 310 nm (UVB) and 340-345 nm (UVA). This means it covers UVB plus the deeper UVA wavelengths that drive photoaging and pigmentation.
Another pro?
It's exceptionally photostable, barely degrades in sunlight, and acts as a "bodyguard" for less stable filters.
That's why you'll see it paired with avobenzone or octinoxate; this team up ensures they keep working through sun exposure.
Safety reviews have been reassuring across the board. This ingredient shows low absorption through the skin, rarely irritates, and lab studies found it doesn't act like a hormone in the body (a concern that's been raised about some older sunscreen filters).
On maximum concentrations:
In 2026, the US F.D.A finally added it as an OTC sunscreen ingredient at concentrations up to 6% for adults / children 6 months and older
Learn more about Bis-Ethylhexyloxyphenol Methoxyphenyl TriazineThis ingredient is used in makeup and skincare to thicken formulas, reduce shine, and give skin a silky-smooth feel.
It’s a white silicone powder that sits in fine lines and pores to blur their appearance though its effectiveness depends on the particle size.
You'll typically find this ingredient in amounts between 0.1-20%.
Learn more about Vinyl Dimethicone/Methicone Silsesquioxane CrosspolymerCopernicia Cerifera Wax comes from a palm tree native to Brazil; another name for this ingredient is Carnauba Wax.
This ingredient is used to thicken texture and also leaves behind a film when applied.
Fun fact: This wax has the highest melting point of all natural waxes and low solubility.
Learn more about Copernicia Cerifera WaxOzokerite is a naturally occuring mineral wax. In cosmetics, ozokerite is used as a texture enhancer.
Ceresin wax is derived from this ingredient.
The melting point of ozokerite is 58-100 C.
Ozokerite is found all over the world including Scotland, the US, and India.
Learn more about OzokeriteMicrocrystalline Wax is derived from petroleum through a de-oiling process, then highly refined and purified before use in cosmetics.
In skincare formulations, it is used to improve texture and create a smooth, even consistency. It also helps stabilize products by preventing ingredients from separating.
Sorbitan Sesquioleate is derived from sorbitol and oleic acid. It is an emulsifier and prevents ingredients from separating.
Specifically, this ingredient is a water-in-oil emulsifier, meaning it helps water dissolve into oil.
Some studies suggest this ingredient may cause irritation in some people. If you are unsure, it is best to patch test.
This ingredient may not be Malassezia folliculitis, or fungal-acne safe due to the oleic acid. In vitro studies have shown that Oleic Acid is one of the fatty acids that induce rapid Malassezia growth in lab settings.
Learn more about Sorbitan SesquioleateBisabolol is a gentle skin conditioner, antioxidant, and soothing ingredient.
It's primary claim to fame is soothing and research shows topically applied bisabolol can quiet the chemical messengers that cause your skin to become inflamed, helping to sooth any irritation.
A clinical study found that applying 0.5% bisabolol daily for 8 weeks produced an average 9% decrease in skin pigmentation. Researchers found it can also suppress the process that leads to excess melanin production in skin.
In vitro studies found that bisabolol combined with propylene glycol significantly increased skin permeability by increasing lipid fluidity in the stratum corneum.
You'll likely see use concentrations quite low, usually 0.1-0.2%.
Overall, this is a well-tolerated ingredient that works well in formulas designed for sensitive, reactive, or post-procedure skin.
Learn more about BisabololSorbitan Olivate is created from the fatty acids in olive oil and sorbitol.
This ingredient is an oil in water emulsifier. It helps stabilize a product by preventing oils and waters from separating. Sorbitan Olivate also helps hydrate the skin.
This ingredient is also known as part of Olivem 1000, with Cetearyl Olivate being the other part.
According to a manufacturer, this ingredient helps preserve the natural microbiome of skin. Having a healthy microbiome helps keep our skin healthy and protects against harmful bacteria.
Please note, having a healthy microbiome is different from fungal acne; a healthy microbiome includes small amounts of yeast that normally live on your skin without causing problems.
Fungal acne happens when one type of yeast (Malassezia) grows out of control. This is usually because it's feeding on certain oils or fatty acids. Due to the olive oil base, this ingredient may not be fungal acne safe.
Learn more about Sorbitan OlivateParfum is a catch-all term for an ingredient or more that is used to give a scent to products.
Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.
For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.
The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.
For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.
One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.
Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.
Parfum can also be used to mask or cover an unpleasant scent.
The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.
Learn more about ParfumHexyl Cinnamal is a fragrance ingredient with a similar scent to jasmine. It can be naturally found in chamomile essential oil.
This ingredient is a known EU allergen and may sensitize the skin. The EU requires this ingredient to be listed separately on an ingredients list.
Hexyl Cinnamal is not water soluble but is soluble in oils.
Learn more about Hexyl CinnamalLinalool is a fragrance and helps add scent to products. It's derived from common plants such as cinnamon, mint, citrus, and lavender.
Like Limonene, this ingredient oxidizes when exposed to air. Oxidized linalool can cause allergies and skin sensitivity.
This ingredient has a scent that is floral, spicy tropical, and citrus-like.
Learn more about LinaloolLimonene is a fragrance that adds scent and taste to a formulation.
It's found in the peel oil of citrus fruits and other plants such as lavender and eucalyptus. The scent of limonene is generally described as "sweet citrus".
Limonene acts as an antioxidant, meaning it helps neutralize free radicals.
When exposed to air, oxidized limonene may sensitize the skin. Because of this, limonene is often avoided by people with sensitive skin.
The term 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term. For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance.
Learn more about LimoneneGeraniol is used to add fragrance/parfum to a product. It is the main component of citronellol. It is a monoterpenoid and an alcohol.
Monoterpenes are naturally found in many parts of different plants.
Geraniol can be found in many essential oils including Rose Oil and Citronella Oil. The scent of Geraniol is often described as "rose-like". Many foods also contain Geraniol for fruit flavoring.
Geraniol can irritate the skin when exposed to air. However, irritation depends on the ability of geraniol to penetrate into the skin. In general, geraniol is not able to penetrate skin easily.
Geraniol is colorless and has low water-solubility. However, it is soluble in common organic solvents.
Like citronellol, it is a natural insect repellent.
2,6-Octadien-1-ol, 3,7-dimethyl-, (2E)-
Learn more about GeraniolCitronellol is used to add fragrance/parfum to a product. It is often derived from plants such as roses. In fact, it can be found in many essential oils including geranium, lavender, neroli, and more. The scent of Citronellol is often described as "fresh, grassy, and citrus-like".
Since the Citronellol molecule is already unstable, Citronellol becomes irritating on the skin when exposed to air.
Citronellol is a modified terpene. Terpenes are unsaturated hydrocarbons found in plants. They make up the primary part of essential oils.
Citronellol is not able to be absorbed into deeper layers of the skin. It has low permeability,
Citronellol is also a natural insect repellent.
Learn more about CitronellolWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinPolyglyceryl-10 Laurate is a cleansing agent and emulsifier.
It rounds up dirt, oil, and grime, so they can be rinsed off easily as a cleanser.
On the emulsifier side, it keeps your formula smooth and well-mixed by playing peacekeeper for ingredients that don't naturally get along (like oil and water).
Because it has a C12 (lauric acid) fatty acid chain, this ingredient can potentially feed the Malassezia yeast that causes fungal acne. The Malassezia yeast prefers esters with C11-C24 fatty acids.
This ingredient is an ester of lauric acid and Polyglycerin-10.
Learn more about Polyglyceryl-10 Laurate1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Learn more about Caprylyl GlycolGinseng root is a well-loved ingredient in Asian skincare for good reason. It hydrates the skin, soothes irritation, and helps even out skin tone.
In traditional East Asian medicine, ginseng has been used for centuries both as food and as a healing remedy, and modern research continues to confirm its skin benefits.
One of the standout features of ginseng is its ability to improve blood circulation and oxygen delivery to the skin, bringing a fresh supply of nutrients to support overall skin health. It also has antioxidant and anti-inflammatory properties. This helps to protect your skin against damage from UV exposure, pollution, and daily stress.
Additionally, studies suggest that ginseng may help reduce hyperpigmentation by inhibiting tyrosinase, the enzyme involved in melanin production.
There are different types of ginseng used in skincare, and while they all share core benefits, their potency can vary.
Most products use fresh or white ginseng because it’s more affordable. However, red ginseng, produced by steaming the root, contains higher levels of ginsenosides, which are compounds with proven anti-aging effects. These ginsenosides help reduce the appearance of wrinkles and improve skin elasticity.
Note: All forms of ginseng are listed simply as “Panax ginseng” in ingredient lists. We recommend reaching out to the brand if you have questions about which type of ginseng is used in their ingredients.
For general antioxidant benefits, any ginseng extract will do, but for wrinkle care or firmer skin, red or fermented ginseng is often more effective.
In short, ginseng is a powerhouse ingredient that supports hydration, radiance, and resilience.
Learn more about Panax Ginseng Root ExtractStar anise extract is used to add a scent to a product. It has a similar smell to black licorice.
Copper Tripeptide-1 (GHK-Cu) is a skin repairing ingredient known for its ability to boost collagen, improve firmness, and support skin regeneration.
It is a complex made up of a naturally occurring peptide (glycine-histidine-lysine) and copper, an essential trace element.
While studying wound healing, researchers noticed GHK-Cu stimulated hair follicle enlargement and growth by keeping hair in its active growth phase longer. This has made it a promising ingredient for hair regrowth treatments.
Some people have reported increased facial hair. While GHK-Cu can make your hair follicles bigger, it usually doesn’t turn soft, barely-visible facial hairs into thick, dark ones.
Anecdotal reports suggest that overusing copper peptides might lead to premature aging due to excess free copper or enzyme imbalances. This claim isn’t backed by large-scale studies.
Unfortunately, there are limited human studies for this ingredient. While early results are promising, many studies are either small, in-vitro, or not rigorously controlled.
For example, there is a 1998 study that explored the effects of copper tripeptide, vitamin C, tretinoin, and melatonin on skin repair and collagen synthesis.
After one month, increased procollagen production was seen in 7 out of 10 participants using copper tripeptide (more than those using vitamin C, melatonin, or tretinoin.
While the study was exploratory, it offers early evidence that copper tripeptide may support collagen production. Larger, well-designed trials are still needed to confirm its potential and understand individual responses.
Read more about other common types of peptides here:
Learn more about Copper Tripeptide-1You might know this ingredient as Matrixyl. It is a synthetic peptide made up of five amino acids attached to a palmitic acid, a fatty acid that helps it absorb into skin more easily.
As a signal peptide, Matrixyl acts like a little messenger. Once it reaches your skin cells, it tells them to ramp up production of collagen, elastin, and other proteins that keep skin looking firm and smooth.
A 12 week clinical study found that a moisturizer containing just 3 ppm of Matrixyl led to a significant improvement in fine-lines and wrinkles. Another study showed an 18% reduction in wrinkle depth, 37% reduction in wrinkle thickness, and a 21% improvement in skin firmness after just 28 days of twice-daily use.
The coolest part is that it works at incredibly low concentrations (like 0.0003%) and it plays well with other actives.
The CIR (Cosmetic Ingredient Review) panel found it to be non-sensitizing across multiple tests and human patch tests also showed no irritation or sensitization.
Fun fact: Matrixyl was originally developed by French company Sederma and Procter & Gamble.
Read more about other common types of peptides here:
Learn more about Palmitoyl Pentapeptide-4Tripeptide-1, also known as GHK), is a small, three-amino-acid peptide made up of glycine, histidine, and lysine.
This ingredient is a signal peptide and tell your skin to start producing fresh collagen, elastin, and other key structural proteins. This helps maintain firmness and reduces the look of fine-lines/wrinkles.
GHK is also unique because is also acts as a carrier peptide. It binds to and transports copper ions (forming the complex GHK-Cu). This form has been studied for decades and is known to stimulate wound healing, boost antioxidant defenses, and promote collagen/elastin synthesis.
In-vitro studies show both GHK and GHK-CU increase fibroblast activity that enhances the production of collagen, elastin, fibronectin, and other extracellular matrix components.
Both of these compounds also help balance enzymes that control collagen breakdown.
Human studies (in-vivo) using GHK-Cu creams have reported visible improvements to skin density, elasticity, and wrinkle depth after several weeks of use.
A small clinical study also found topical collagen tripeptide improved wrinkle appearance and skin elasticity in women after four weeks.
While these results are promising, most research is based on GHK-Cu or its derivatives rather than Tripeptide-1 alone (Palmitoyl Tripeptide-1 is a famous derivative of GHK). However, the consensus still supports GHK as a potent skin-signaling molecule that can encourage regeneration and maintain youthful looking skin.
Fun fact: GHK is a naturally occurring fragment of type 1 collagen that can be found in human plasma, saliva, and urine.
Learn more about Tripeptide-1Palmitoyl Tripeptide-1 (aka Pal-GHK) is a synthetic signal peptide made of three amino acids attached to palmitic acid.
That fatty acid attachment is the key: it boosts the peptide's ability to penetrate the skin barrier. This puts it closer to the dermal cells where it can actually make a difference.
Once there, it acts as a matrikine, a signaling peptide that prompts fibroblasts to produce more collagen, fibronectin, and hyaluronic acid.
In vitro studies show it can boost collagen production in skin cells even when UV-damaged skin samples were treated with it at a tiny concentration (it almost fully restored dermal collagen at 5ppm). It achieved this at 100x lower concentration than retinoic acid, which needed 500 ppm to do the same thing.
Human clinical data is promising, but modest:
A study of 23 female volunteers found a small but statistically significant increase (~4%) in skin thickness after treatment at 4 ppm.
A separate small trial of 15 women showed statistically significant reductions in wrinkle length, depth, and skin roughness after applying it twice daily for four weeks.
You'll likely see Pal-GHK paired with Palmitoyl Tetrapeptide-7 as part of the Matrixyl 3000 complex.
Fungal acne note:
Usually a palmitic acid component can feed Malassezia in unbound form, but here is is covalently bonded to the peptide. This means it is very difficult for Malassezia to access, and therefore very unlikely to cause fungal acne.
Hexapeptide-9 is a signaling peptide that is made to mimic a fragment found naturally in collagen IV and XVII.
It is classified as a matrikine peptide and works by telling your skin cells (especially fibroblasts) to ramp up collagen and hyaluronic acid production.
In-vitro studies show it can enhance epidermal regeneration, boost synthesis of collagen types I, III, and IV, and improved markers of skin differentiation.
Think of skin differentiation like this: your skin cells are born at the bottom and slowly travel up to the surface as they "grow up". As they move up, they start producing specific proteins that make your skin do its job well. Two of these proteins are keratin (it makes your skin tough) and filaggrin (it breaks apart into tiny molecules to keep your skin hydrated). So Hexapeptide-9 has shown to help skin cells grow up properly and make stronger, more hydrated skin.
A manufacturer also reports increased collagen production by 117% and hyaluronic acid production by 267%.
Just know much of the published data comes from manufacturer-sponsored studies. There is a recent clinical trial showing promising anti-aging results but the evidence base is still growing.
Generally, this ingredient is well-tolerated and there's no harm in using it as a supportive ingredient in your routine.
Learn more about Hexapeptide-9This synthetic peptide is known as a signal peptide. Signal peptides tell your skin to create more collagen, elastin and protein.
Hexapeptide-11 is composed of several amino acids, including alanine.
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Where it's from
Sola Beauty is a Filipino brand
50 SPF Rating
With an SPF rating of 50, this product protects against 98.0% of UVB rays
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We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about us· Updated March 29, 2025 • Added by biancaabad