Overview
What it is
Scalp treatment with 30 ingredients that contains BHA
Cool Features
It is reef safe
Suited For
It has ingredients that are good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and better texture
Free From
It doesn't contain any oils, parabens, silicones or sulfates
Fun facts
Nineless is from South Korea. This product is used in 2 routines created by our community.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside
Ingredients List
Saccharomyces Cerevisiae Extract
Skin ConditioningWater
Skin ConditioningAlcohol
Antimicrobial1,2-Hexanediol
Skin ConditioningButylene Glycol
HumectantPolysorbate 80
EmulsifyingGlycerin
HumectantMenthol
MaskingArginine
MaskingSalicylic Acid
MaskingPanthenol
Skin ConditioningEthylhexylglycerin
Skin ConditioningDisodium EDTA
Parfum
MaskingAllantoin
Skin ConditioningChamaecyparis Obtusa Water
MaskingCentella Asiatica Extract
CleansingCornus Officinalis Fruit Extract
Skin ConditioningRehmannia Chinensis Root Extract
Skin ConditioningAlisma Orientale Tuber Extract
Skin ConditioningDioscorea Japonica Root Extract
Skin ConditioningPaeonia Suffruticosa Root Extract
Skin ProtectingPoria Cocos Sclerotium Extract
AstringentRosa Centifolia Flower Water
Skin ConditioningHamamelis Virginiana Water
AstringentCoix Lacryma-Jobi Ma-Yuen Seed Extract
Skin ConditioningMorus Alba Bark Extract
Skin ConditioningCamellia Sinensis Leaf Extract
AntimicrobialHouttuynia Cordata Extract
Skin ConditioningAvena Sativa Protein Extract
Skin ConditioningSaccharomyces Cerevisiae Extract, Water, Alcohol, 1,2-Hexanediol, Butylene Glycol, Polysorbate 80, Glycerin, Menthol, Arginine, Salicylic Acid, Panthenol, Ethylhexylglycerin, Disodium EDTA, Parfum, Allantoin, Chamaecyparis Obtusa Water, Centella Asiatica Extract, Cornus Officinalis Fruit Extract, Rehmannia Chinensis Root Extract, Alisma Orientale Tuber Extract, Dioscorea Japonica Root Extract, Paeonia Suffruticosa Root Extract, Poria Cocos Sclerotium Extract, Rosa Centifolia Flower Water, Hamamelis Virginiana Water, Coix Lacryma-Jobi Ma-Yuen Seed Extract, Morus Alba Bark Extract, Camellia Sinensis Leaf Extract, Houttuynia Cordata Extract, Avena Sativa Protein Extract
Key Ingredients
Benefits
Concerns
Ingredients Explained
Saccharomyces Cerevisiae Extract comes from a yeast used in fermentation. It has skin conditioning properties due to its naturally occurring peptides, polysaccharides (including beta-glucans), amino acids, minerals, and vitamins.
Clinical research shows formulas that contain this ingredient can improve moisture levels and refine skin texture over time. This is associate with its ability to reduce free-radical activity and protect the skin against environmental damage.
Lab studies demonstrate that some peptide fractions in this ingredient possess antioxidant and anti-collegenase effects, helping to protect the structural proteins in skin and soothing inflammation.
Additionally, this ingredient has been shown to have antimicrobial effects against bacteria associated with acne.
Learn more about Saccharomyces Cerevisiae ExtractWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterThis ingredient is also called ethanol or ethyl alcohol. It is denatured, meaning made undrinkable for cosmetic use.
In formulas, it:
Is it bad for your skin?
The answer comes down to concentration. Patch and wash studies have found highly concentrated alcohol-based hand rubs (60-100%) cause less barrier disruption than washing with a basic detergent like SLS. The only measurable effect in these studies was a temporary dip in skin hydration.
Concentrations below 12-15% in leave-on cosmetics is generally well-tolerated. Concentrations above start to see increased transepidermal water loss (TEWL) and reduced hydration.
In concentrations about 58%, it creates temporary channels in your skin's lipid layers to become more permeable and allow other ingredients to slip through easily.
This ingredient can be up to 80% of the formula in alcohol-based perfumes.
Overall, this ingredient is probably harmless if found lower down an ingredients list but worth side-eyeing if it's high up (especially if your barrier is already struggling).
Alcohol can worsen dry skin, eczema, and oily skin, especially at higher concentrations. This is because it can increase transepidermal water loss and decrease hydration to disrupt the skin barrier.
According to the National Rosacea Society based in the US, you should be mindful of products with these alcohols in the top half of ingredients.
True allergic contact dermatitis to ethanol is uncommon, but be sure to patch test if you have dry or sensitive skin.
Learn more about Alcohol1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.ย
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservativesย
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolPolysorbate 80 is a surfactant and emulsifier. It is used to keep ingredients together, and prevent oils and waters from separating.
It is made from polyethoxylated sorbitan and oleic acid. This ingredient can be found in cosmetics, foods, and medicine. It is water-soluble.
Polysorbate 80 may not be fungal acne safe.
Learn more about Polysorbate 80Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinMenthol is a compound found in mint plants, such as peppermint. In its pure form, it is a clear crystalline substance.
Menthol is known for its cooling sensation; however, the cooling is actually from your skin being sensitized. Menthol can worsen rosacea. We recommend speaking with a professional if you have concerns.
Menthol also has antimicrobial properties.
Learn more about MentholArginine is a semi-essential amino acid. This just means our bodies can product a bit on its own, but sometimes needs a little boost from food sources.
It is a part of your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
Here's an interesting thing about Arginine: your skin converts it into urea through the Krebs-Henseleit urea cycle. Urea is one of the most effective humectants your skin naturally produces.
A clinical study showed applying 2.5% arginine hydrochloride to atopic dermatitis skin showed significant urea levels in the stratum corneum and improved moisture in just four weeks.
Arginine is also a precursor to nitric oxide; nitric oxide improves microcirculation and supports wound healing and collagen synthesis.
One study found that an amino acid complex containing Arginine reduced skin irritation, improved hydration, and accelerated skin repair in clinical / in-vivo studies.
Arginine itself is an amino acid and not a fatty acid, oil, or ester. On its own, it's not a direct food source for Malassezia, or the yeast that causes fungal acne.
Learn more about ArginineSalicylic Acid (also known as beta hydroxy acid or BHA) is a well-known ingredient for treating skin that struggles with acne and clogged pores. It exfoliates both the skin's surface and deep within the pores to help clear out buildup, control oil, and reduce inflammation.
Unlike AHAs (alpha hydroxy acids), salicylic acid is oil-soluble. This allows it to penetrate into pores which makes it especially effective for treating blackheads and preventing future breakouts.
Salicylic acid is also known for its soothing properties. It has a similar structure to aspirin and can calm inflamed or irritated skin, making it a good option for acne-prone skin that is also sensitive.
Concentrations of 0.5-2% are recognized by the U.S. FDA as an over-the-counter topical acne product.
It can cause irritation and/or dryness if one's skin already has a compromised moisture barrier, so it's best to focus on repairing that before introducing this ingredient into your routine.
While salicylic acid does not increase sun sensitivity, itโs still important to wear sunscreen daily to protect your skin.
If you are looking for the ingredient called BHA or Butylated Hydroxyanisole, click here.
Learn more about Salicylic AcidPanthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Learn more about PanthenolEthylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinDisodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Learn more about Disodium EDTAParfum is a catch-all term for an ingredient or more that is used to give a scent to products.
Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.
For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of โFRAGRANCEโ or โPARFUMโ according to EU and US regulations.
The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.
For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.
One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.
Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.
Parfum can also be used to mask or cover an unpleasant scent.
The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.
Learn more about ParfumAllantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.
Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.
Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.
It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.
Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.
This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.
Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.
Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.
Learn more about AllantoinThis ingredient is also known as Hinoki water. It is made by steam distilling the Japanese cypress tree.
Functionally, this ingredient is often used as a water replacement and concentrations can go as high up as 65%; this just means its more-so used to shape the base of a formula than as a star active.
The water carries small amounts of the tree's volatile compounds that give it a soft and woody scent.
Most of the published skin research is related to the essential oil or leaf extract rather than this water form; these cell and mice studies should antioxidant, antibacterial, and anti-inflammatory effects.
This ingredient only contains a small amount of these beneficial compounds but can still provide some soothing.
The Hinokitiol compound in this water is also antifungal against Malassezia; this can make it a great option for those with fungal acne.
However, those with fragrance sensitivity should patch test.
Fun fact: The Japanese 'Hinoki' Cypress tree is traditionally used to build shrines and temples.
Learn more about Chamaecyparis Obtusa WaterCentella Asiatica Extract (Centella) is derived from an herb native to Southeast Asia. It is famous for its anti-inflammatory and soothing properties.
Centella is rich in antioxidants and amino acids, such as Madecassic Acid and Asiaticoside.
Studies show the compounds in centella help with:
The combination of all these properties makes centella effective at soothing, hydrating, and protecting the skin.
Other great components of centella include Vitamin A, vitamin C, several B vitamins, and Asiatic Acid.
Fun fact: Centella has been used as a medicine and in food for many centuries. As a medicine, it is used to treat burns, scratches, and wounds.
Learn more about Centella Asiatica ExtractWe don't have a description for Cornus Officinalis Fruit Extract yet.
We don't have a description for Rehmannia Chinensis Root Extract yet.
We don't have a description for Alisma Orientale Tuber Extract yet.
This ingredient comes from the Asian mountain yam and has skin conditioning properties. Clinical studies have confirmed this ingredient to work as an effective moisturizer.
The extract is rich in compounds like diosgenin, polysaccharides, and polyphenols, gallic acid, and vanillic acid. Research on these extracts has demonstrated antioxidant effects in-vitro and anti-inflammatory activity in animal models.
The bioactives in the root extract have also been shown in lab tests to have anti-wrinkle, antioxidant, and anti-allergy properties.
A big 2022 review looked at the whole Dioscorea family and found these plants consistently showed antioxidant activity across the board.
This ingredient is gentle and well-tolerated by all skin types.
Learn more about Dioscorea Japonica Root ExtractPaeonia Suffruticosa Root Extract comes Peony plant. It has anti-inflammatory and antioxidant properties.
Emerging studies also show peony root may help reduce hyperpigmentation.
Ancient Chinese medicine has used peony root to treat dark spots, but studies are looking into this claim more.
Learn more about Paeonia Suffruticosa Root ExtractWe don't have a description for Poria Cocos Sclerotium Extract yet.
Rosa Centifolia Flower Water is the steam distilled water from the petals of Rosa centifolia, a rose cultivated in France, Bulgaria, and Morocco. It has skin conditioning and soothing properties due to its rich antioxidant content.
Since it's the water-soluble part of distilling rose petals, it's lighter and more dilute than rose extract or essential oil.
Research suggests it can help counteract the enzymes involved in the breakdown of collagen and elastin and have antimicrobial activity against acne-related microorganisms. A comprehensive 2025 review confirmed that Rosa centifolia extracts demonstrate anti-inflammatory, antimicrobial, and antioxidant effects.
Learn more about Rosa Centifolia Flower WaterHamamelis Virginiana Water is made by distilling parts of the witch hazel plant. You can also call this ingredient "witch hazel water".
The name 'Hamamelis Virginiana Water' refers to the distillation product used in cosmetics. On the other hand, 'Witch Hazel' refers to the active drug ingredient.
Unless it is specified to be non-alcohol, many types of witch hazel ingredients are distilled in denatured alcohol.
Witch Hazel water is an astringent, anti-inflammatory antioxidant, and antibacterial ingredient.
It contains tannins. Tannins have a drying effect when used on skin by constricting proteins. The constriction also minimizes the appearance of pores.
Both the tannins and fragrance found in witch hazel may be skin-sensitizing.
Witch hazel water gets anti-inflammatory and antibacterial properties from its catechin and gallic acid content.
Indigenous groups have used witch hazel to help treat inflammation in North America for centuries.
Learn more about Hamamelis Virginiana WaterYou might know this plant as Job's Tears or Chinese pearl barley. It is a grain native to Southeast Asia.
This ingredient has skin conditioning properties. Emerging studies show the grain to exhibit antioxidant and anti-inflammation properties as well. (With one study finding this ingredient to be effective at blocking melanin when skin is exposed to UV).
Job's tears is rich in nutrients, such as thiamine, riboflavin, niacin and ascorbic acid.
You can also find great antioxidants such as ferulic acid, caffeic acid.
To top if off, ceramides are also present in this grain.
Learn more about Coix Lacryma-Jobi Ma-Yuen Seed ExtractWe don't have a description for Morus Alba Bark Extract yet.
Camellia Sinensis Leaf Extract (tea extract) is one of the most well-researched plant extracts in skincare with an impressive resume.
Black tea, green tea, and oolong tea are all harvested from the Camellia Sinensis plant.
Studies show green tea extract and its catechins (like epigallocatechin gallate (EGCG)) help your skin cells product energy more efficiently and reducing the number of free-radicals that can damage your skin from the inside.
In lab-grown skin models, this translated to younger, healthier, and stronger skin.
There's also good sun protection data; researchers saw less DNA damage and redness on human skin when green tea was applied before UVB exposure. And the more they applied, the better the protection.
Needless to say, this ingredient shouldn't replace your sunscreen. But it is a great supportive ingredient that you can already find in many sunscreens and antioxidant serums.
A 2009 study found a 2% green tea lotion was effective for mild-to-moderate acne thanks to its anti-inflammatory and mild antimicrobial activity.
The quality of the extract matters a lot here:
Good extracts contain 50-90% catechins while lower quality ones are mostly there for marketing. We recommend reaching out to the brand if you have questions about the quality or source of their ingredients.
Human Repeated Insult Patch Testing showed no irritation or sensitization at use concentrations (0.86% in leave-on products and up to 30% as leaf water).
Learn more about Camellia Sinensis Leaf ExtractHouttuynia Cordata Extract is more commonly known as Heart Leaf, Fish Mint, or Chameleon plant.
The components found in Heart Leaf give it antioxidant, hydrating, antimicrobial, and anti-inflammatory properties.
Heart Leaf is rich in flavonoids such as quercetin, apigenin, and more. It also contains polysaccharides, the most common type of carbs in food.
Flavonoids have been shown to be effective antioxidants. They help neutralize free-radical molecules. Free-radical molecules are unstable molecules that may damage our skin cells and DNA. The flavonoids in Heart Leaf also help soothe the skin.
Polysaccharides are naturally found in our skin. They play a role in hydrating and repairing the top layer of skin. The polysaccharides in Heart Leaf help moisturize our skin.
Studies show decanoyl acetaldehyde, a component of Heart Leaf oil, is effective at killing bacteria.
The name 'Fish Mint' comes from the herb's natural fishy smell. Is is native to southeast Asia and used throughout the continent for traditional cooking and medicine.
Learn more about Houttuynia Cordata ExtractWe don't have a description for Avena Sativa Protein Extract yet.
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Where it's from
Nineless is a Korean brand
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Read more about usยท Updated October 25, 2023