MEDI-PEEL Green Cica Collagen Clear 2.0
A face cleanser with 57 ingredients, including AHA, PHA, and hyaluronic acid.
Overview
What it is
Face cleanser with 57 ingredients that contains AHA, ceramides, hyaluronic acid and PHA
Cool Features
It is cruelty-free, fungal acne (malassezia) safe, and reef safe
Suited For
It has ingredients that are good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and better texture
Free From
It doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates
Fun facts
MEDI-PEEL is from South Korea. This product is used in 4 routines created by our community.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside
Ingredients List
Water
Skin ConditioningGlycerin
HumectantCoco-Betaine
CleansingPotassium Cocoate
EmulsifyingPotassium Cocoyl Glycinate
Acrylates Copolymer
1,2-Hexanediol
Skin ConditioningSodium Chloride
MaskingHydroxypropyl Starch Phosphate
Ethylhexylglycerin
Skin ConditioningCitric Acid
BufferingMethylpropanediol
SolventCentella Asiatica Extract
CleansingIris Florentina Root Extract
MaskingPyrus Communis Fruit Extract
Skin ConditioningButylene Glycol
HumectantVanilla Planifolia Fruit Extract
Skin ConditioningHedera Helix Leaf/Stem Extract
AntimicrobialGluconolactone
Skin ConditioningRubus Suavissimus Leaf Extract
Skin ConditioningOphiopogon Japonicus Root Extract
Skin ConditioningLactobacillus/Water Hyacinth Ferment
Skin ProtectingXylitylglucoside
HumectantChrysanthemum Morifolium Flower Extract
Skin ConditioningAnhydroxylitol
HumectantCaprylic/Capric Triglyceride
MaskingXylitol
HumectantCollagen
MoisturisingCeramide NP
Skin ConditioningMadecassoside
AntioxidantHydrogenated Lecithin
EmulsifyingHydrolyzed Collagen
EmollientGlycine
BufferingSerine
MaskingGlutamic Acid
HumectantBiosaccharide Gum-4
Skin ConditioningSodium Hyaluronate
HumectantAspartic Acid
MaskingLeucine
Skin ConditioningAsiaticoside
AntioxidantPanthenol
Skin ConditioningAsiatic Acid
Skin ConditioningMadecassic Acid
Skin ConditioningAlanine
MaskingLysine
Skin ConditioningArginine
MaskingTyrosine
MaskingPhenylalanine
MaskingThreonine
Proline
Skin ConditioningValine
MaskingIsoleucine
Skin ConditioningHistidine
HumectantMethionine
Skin ConditioningCysteine
AntioxidantCollagen Extract
Skin ConditioningPotassium Sorbate
PreservativeWater, Glycerin, Coco-Betaine, Potassium Cocoate, Potassium Cocoyl Glycinate, Acrylates Copolymer, 1,2-Hexanediol, Sodium Chloride, Hydroxypropyl Starch Phosphate, Ethylhexylglycerin, Citric Acid, Methylpropanediol, Centella Asiatica Extract, Iris Florentina Root Extract, Pyrus Communis Fruit Extract, Butylene Glycol, Vanilla Planifolia Fruit Extract, Hedera Helix Leaf/Stem Extract, Gluconolactone, Rubus Suavissimus Leaf Extract, Ophiopogon Japonicus Root Extract, Lactobacillus/Water Hyacinth Ferment, Xylitylglucoside, Chrysanthemum Morifolium Flower Extract, Anhydroxylitol, Caprylic/Capric Triglyceride, Xylitol, Collagen, Ceramide NP, Madecassoside, Hydrogenated Lecithin, Hydrolyzed Collagen, Glycine, Serine, Glutamic Acid, Biosaccharide Gum-4, Sodium Hyaluronate, Aspartic Acid, Leucine, Asiaticoside, Panthenol, Asiatic Acid, Madecassic Acid, Alanine, Lysine, Arginine, Tyrosine, Phenylalanine, Threonine, Proline, Valine, Isoleucine, Histidine, Methionine, Cysteine, Collagen Extract, Potassium Sorbate
Key Ingredients
Benefits
Concerns
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinCoco-Betaine is the natural version of Cocamidopropyl Betaine. It is often derived from coconuts.
Coco-Betaine is a surfactant, meaning it helps remove dirt and oil from the skin.
This ingredient is the potassium salt of coconut acid. Coconut acid is created by mixing fatty acids from coconut oil.
It is an emulsifier, surfactant, and cleanser. According to a manufacturer, it contains glycerin.
Potassium Cocoyl Glycinate is an amino acid-based surfactant and cleaning agent. This ingredient can be derived from animals or plants. It may also be synthetically created from fatty acids of the coconut and glycine.
Potassium Cocoyl Glycinate is a gentle surfactant. Surfactants help gather the dirt, oil, and other pollutants from your skin to be rinsed away. It is a mild cleanser and naturally produces foam.
Acrylates Copolymer is used as a film-forming agent and texture enhancer.
After applied, Acrylates Copolymer forms a thin film cover that helps skin feel more soft. It can help sunscreens become more water-resistant.
It is also used to make a product more thick.
Learn more about Acrylates Copolymer1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.ย
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservativesย
Chances are, you eat sodium chloride every day. Sodium Chloride is also known as table salt. This ingredient has many purposes in skincare: thickener, emulsifier, and exfoliator.
You'll most likely find this ingredient in cleansers where it is used to create a gel-like texture. As an emulsifier, it also prevents ingredients from separating.
You might see people debate whether Sodium Chloride is comedogenic, but there actually haven't been any comedogenic tests done on it. Either way, the overall formulation of a product matters a lot more than any single ingredient.
You might see this ingredient used in scrubs as a primary exfoliating ingredient.
Learn more about Sodium ChlorideHydroxypropyl Starch Phosphate is a modified starch used to help thicken a product.
It is also used in foods.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinCitric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
In skincare formulas, citric acid can:
While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
Read more about some other popular AHA's here:
Learn more about Citric AcidMethylpropanediol is a synthetic solvent and humectant.
As a solvent, it helps dissolve other ingredients, helping to evenly distribute ingredients throughout the product. This ingredient has also been shown to have antimicrobial properties which makes it a preservative booster.
Methylpropanediol is able to add a bit of moisture to the skin. It also helps other ingredients be better absorbed into the skin, such as salicylic acid.
Learn more about MethylpropanediolCentella Asiatica Extract (Centella) is derived from an herb native to Southeast Asia. It is famous for its anti-inflammatory and soothing properties.
Centella is rich in antioxidants and amino acids, such as Madecassic Acid and Asiaticoside.
Studies show the compounds in centella help with:
The combination of all these properties makes centella effective at soothing, hydrating, and protecting the skin.
Other great components of centella include Vitamin A, vitamin C, several B vitamins, and Asiatic Acid.
Fun fact: Centella has been used as a medicine and in food for many centuries. As a medicine, it is used to treat burns, scratches, and wounds.
Learn more about Centella Asiatica ExtractWe don't have a description for Iris Florentina Root Extract yet.
This ingredient comes from the common pear and has skin conditioning/skin protecting properties. Pears are rich in bioactive phenolic compounds, with the most notable ones being Arbutin, Chlorogenic Acid, and Catechin.
A small in-vivo study with 13 volunteers found using a 5% pear extract gel over 12 weeks significantly improved skin moisture and elasticity, and decreased melanin and sebum levels compared to placebo.
In phytochemical analysis, this extract has also demonstrated anti-tyrosinase activity which further supports its brightening properties.
Just so you know, individuals with birch pollen allergy should be careful and patch test this ingredient as pears belong to the same family. But topical use of this ingredient is generally well-tolerated.
Learn more about Pyrus Communis Fruit ExtractButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolVanilla Planifolia Fruit Extract comes from the vanilla orchid native to central America. It is a skin-soothing ingredient.
This ingredient is skin-soothing and contains polyphenols that give it antioxidant properties.
This ingredient is not known to sensitize or irritate skin (unlike Vanilla Tahitensis). Vanilla tahitensis has shown to irritate skin in low amounts.
Learn more about Vanilla Planifolia Fruit ExtractThis ingredient comes from the English Ivy, a climbing evergreen plant. The extract is rich in compounds that give it antioxidant, skin conditioning, and anti-inflammatory properties.
Two of the compounds, Alpha-Hederin and Hederasaponin-C, showed strong inhibition of shown to be effective at protecting against oxidative damage as well as synthetic antioxidants like butylated hydroxyanisole and BHT.
Gluconolactone is a PHA. PHAs are a great gentle alternative to traditional AHAs.
When applied, Gluconolactone has the same affect on skin as AHAs such as lactic acid. It helps dissolve the dead skin cells in the top layer of your skin. This improves texture and brightens the skin.
PHAs are more gentle than AHAs due to their larger structure. They do not penetrate as deeply as AHAs and take a longer time to dissolve dead cells. Studies show PHAs do not cause as much irritation.
Gluconolactone has some interesting properties:
In a 2004 study, Gluconolactone was found to prevent UV damage in mouse skin cells and has not been found to increase sun sensitivity. However, we still recommend wearing SPF daily.
This ingredient is is an created by reacting gluconic acid with an alcohol.
Learn more about GluconolactoneWe don't have a description for Rubus Suavissimus Leaf Extract yet.
We don't have a description for Ophiopogon Japonicus Root Extract yet.
We don't have a description for Lactobacillus/Water Hyacinth Ferment yet.
Xylitylglucoside is created from xylitol and glucose, two humectants.
Not surprisingly, this ingredient is also a humectant. It attracts and holds water in your skin, helping to maintain hydration.
This ingredient is most commonly found in a popular trio called Aquaxyl. Aquaxyl is made up of anhydroxylitol(24 - 34%), xylitylglucoside (35 - 50%), and xylitol (5 - 15%).
According to a manufacturer, Aquaxyl is known for a 3-D hydration concept and an anti-dehydration shield to reinforce the outer layer of skin.
Learn more about XylitylglucosideWe don't have a description for Chrysanthemum Morifolium Flower Extract yet.
This ingredient is created from dehydrating xylitol in acidic conditions. Xylitol is a famous sugar and humectant.
Much like its predecessor, anhydroxylitol is a humectant. Humectants attract and hold water to moisturize the skin.
This ingredient is most commonly found in a popular trio called Aquaxyl. Aquaxyl is made up of anhydroxylitol (24 - 34%), xylitylglucoside (35 - 50%), and xylitol (5 - 15%).
According to a manufacturer, Aquaxyl is known for a 3-D hydration concept and an anti-dehydration shield to reinforce the outer layer of skin.
This ingredient is often derived from plants such as wood and sugarcane.
Learn more about AnhydroxylitolThis ingredient is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.
It helps thicken a product's formula and makes it easier to spread by dissolving clumping compounds.
Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid. Though it behaves like an oil, it is not technically one due to its chemical composition. It is very stable, resistant to oxidation, and unlikely to go rancid. In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Be sure to patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredientโs final chemical composition and not its marketing name or source.
Learn more about Caprylic/Capric TriglycerideXylitol is a humectant and prebiotic. It can help with dry skin.
In studies, xylitol has been shown to improve dry skin. It decreased transepidermal water loss, or when water passes through the skin and evaporates. Xylitol also showed to help improve the biomechanical properties of the skin barrier.
The prebiotic property of xylitol may also help reinforce our skin's natural microbiome. Having a healthy microbiome prevents infection by bad bacteria and helps with hydration.
As a humectant, Xylitol helps draw moisture from both the air and from deeper skin layers. This helps keep skin hydrated.
Xylitol is a sugar alcohol and commonly used as a sugar substitute. It is naturally occurring in plants such as strawberries and pumpkin.
Learn more about XylitolCollagen is the most abundant type of structural protein found in your body. It is an effective skin moisturizer.
There is no conclusive proof that collagen is used by skin when applied topically. However, it is a great humectant that hydrates skin. Hydrated skin is associated with increased elasticity and a decrease in the appearance of wrinkles. It is also essential for maintaining a healthy skin barrier.
Biologically, collagen is responsible for keeping skin firm and youthful. Collagen is comprised mostly of glycine, proline, and hydroxypoline. These are amino acids.
Collagen will not increase sun sensitivity, but you should always wear sunscreen during the day.
Learn more about hydrolyzed collagen here.
Learn more about CollagenCeramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.
Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.
This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.
A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.
Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.
Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.
Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.
Learn more about Ceramide NPMadecassoside is one of four active compounds found in Centella asiatica and is one of the main reasons Centella is so effective at calming irritated skin and supporting the moisture barrier.
There's a solid body of peer-reviewed research backing Madecassoside for several skin benefits. Studies have found:
Madecassoside pairs well with other hydrating or antioxidant ingredients like Ascorbic Acid or Hyaluronic Acid.
Learn more about MadecassosideHydrogenated Lecithin is a more stable version of lecithin.
It's made by taking lecithin (a phospholipid commonly found in soybeans and egg yolks) and hydrogenating it. This just means the unsaturated fatty acids are turned into saturated ones so they don't go bad as easily.
This ingredient is an emollient, emulsifier, and penetration enhancer. As an emollient, it helps soften and hydrate skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.
Hydrogenated Lecithin can form tiny spherical structures made of phospholipid bilayers called liposomes. These liposomes are able to capture compounds inside their structure and deliver them through the skin barrier.
Because phospholipids are a natural component of our cell membranes, this ingredient is inherently compatible with skin.
A 2021 study found lecithin-based surfactants were less harsh and more tolerable comared to Sodium Lauryl Sulfate (SLS).
Learn more about Hydrogenated LecithinHydrolyzed collagen has a misleading name because it is actually a mixture of various proteins/peptides. This ingredient has skin hydrating properties.
Collagen is the most abundant type of structural protein found in your body. In your skin, it is responsible for keeping it firm and youthful.
Hydrolyzed Collagen is created by breaking up proteins into smaller peptide bonds. These peptides act as humectants and emollients.
Humectants are great at holding onto water, keeping skin hydrated. Emollients create a thin barrier on the skin to prevent moisture from escaping.
There is ongoing debate about whether hydrolyzed collagen works because it increases skin hydration. Skin hydration is also linked to elasticity and the appearance of wrinkles.
Collagen or peptide ingredients can be used in the morning or night. They will not increase sun sensitivity, but you should always wear sunscreen during the day.
According to a manufacturer, this ingredient is a great hair conditioner as well.
This ingredient can be extracted from different sources, including:
Vegan collagen is derived from yeast, bacteria, or plant sources. Vegan collagen would go by a different INCI name, such as hydrolyzed soy protein.
The results are varied.
A study from 2021 found hydrolyzed collagen increased elasticity and improved wrinkles in 1,125 participants between age 20 and 70. Another study found increased skin thickness in participants between the ages of 45 to 59.
However, It is difficult to prove that oral collagen will end up working on your skin. Many of the studies using hydrolyzed collagen also add several vitamins and nutrients into the test mixture as well.
Further studies are needed at this time.
Learn more about Hydrolyzed CollagenGlycine is the smallest amino acid and a key building block of collagen. It's part if your skin's Natural Moisturizing Factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
A study from 2022 found that an amino acid complex featuring taurine, arginine, and glycine significantly reduced skin irritation, improved redness, and accelerated the skin repair process.
Serine is a non-essential amino acid (your body makes it on its own!). It is a major player in your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
Serine is one of your NMF's most abundant components that works as a skin-identical humectant. Its hydroxyl group grabs onto water molecules to boost hydration without any heaviness or occlusion.
Research on a hydrogel with serine confirmed this serine got delivered to your stratum corneum and demonstrated enhanced skin moisturization.
Interestingly serine also helps your skin produce filaggrin, a protein that keeps your skin barrier strong and used to create collagen.
Learn more about SerineGlutamic Acid is an amino acid that is found in all living organisms. Our bodies use this to help nerve cells in the brain communicate with other cells.
In cosmetics, glutamic acid is a famous humectant. It draws water from the air to your skin, keeping your skin hydrated (like hyaluronic acid).
An in-vitro study from 2024 found glutamic acid to play a role in inhibiting inflammation and thus a potential skin-soothing ingredient.
Other studies show it to be have potential wound healing, skin barrier repair, and hair growth properties.
Glutamic acid has poor solubility in water and other solvents.
Learn more about Glutamic AcidThis is a fermented gum derived from sorbitol, a sugar alcohol.
According to a manufacturer, this ingredient's high molecular weight makes it an effective emollient.
Emollients help keep the skin hydrated by preventing water from evaporating.
Learn more about Biosaccharide Gum-4Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Learn more about Sodium HyaluronateAspartic Acid is an amino acid that our bodies produce naturally. It is an antioxidant.
Our body uses Aspartic Acid to help build collagen and elastin. It also plays a role in hydrating skin.
We don't have a description for Leucine yet.
Asiaticoside comes from the super popular skin-soothing ingredient, Centella asiatica. It's the reason centella-based products have a strong reputation for repairing and calming skin, along with its sibling compound Madecassoside.
Research from 2016-2025 supports its role in:
You'll usually find this in concentrations between 0.2-5%.
Learn more about AsiaticosidePanthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Learn more about PanthenolAsiatic Acid is a major component of Centella Asiatica Extract. It has wound-healing, anti-inflammatory, and antioxidant properties.
Studies show Asiatic Acid is able to block the pathway for skin inflammation receptors, helping to soothe skin.
As an antioxidant, asiatic acid helps protect our skin against damaging environmental factors.
Learn more about Asiatic AcidMadecassic Acid is a major component of Centella Asiatica Extract. It has anti-inflammatory and antioxidant properties.
It is a triterpenoid, meaning it naturally acts as an antioxidant. Antioxidants protect your skin against damage from environmental factors such as pollution and UV.
Studies show Madecassic Acid helps soothe the skin due to its ability to block inflammation pathways.
Learn more about Madecassic AcidAlanine is an amino acid and is already found in the human body. Our skin uses alanine to build collagen, elastin, and keratin.
Lysine is an essential amino acid (your body cannot make it on its own). It has skin conditioning properties and one of the key players in collagen synthesis.
When your body creates collagen, lysine is basically the glue that holds everything together. It helps collagen fibers lock into each other and stay strong, with vitamin C being its trusty sidekick. Without enough lysine, this glue gets flimsy and less firm, resulting in less bouncy skin.
In skincare, lysine is mostly there to help keep your skin moisturized. It carries water through your skin's layers so everything stays plump.
So will putting lysine on your face create bouncier skin?
It's hard to say; most of the exciting collagen research on lysine comes from oral supplements or lab studies on mice. Further research is needed to truly understand what role topical lysine plays in skincare and your skin.
However, there's no harm in adding lysine to your routine as a supportive and hydrating ingredient.
Learn more about LysineArginine is a semi-essential amino acid. This just means our bodies can product a bit on its own, but sometimes needs a little boost from food sources.
It is a part of your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
Here's an interesting thing about Arginine: your skin converts it into urea through the Krebs-Henseleit urea cycle. Urea is one of the most effective humectants your skin naturally produces.
A clinical study showed applying 2.5% arginine hydrochloride to atopic dermatitis skin showed significant urea levels in the stratum corneum and improved moisture in just four weeks.
Arginine is also a precursor to nitric oxide; nitric oxide improves microcirculation and supports wound healing and collagen synthesis.
One study found that an amino acid complex containing Arginine reduced skin irritation, improved hydration, and accelerated skin repair in clinical / in-vivo studies.
Arginine itself is an amino acid and not a fatty acid, oil, or ester. On its own, it's not a direct food source for Malassezia, or the yeast that causes fungal acne.
Learn more about ArginineTyrosine is one of the amino acids used to create protein. It plays a role in melanin production.
A study from 2012 found tyrosine to show promising results in restoring skin volume.
Phenylalanine is an amino acid. It is a skin soothing and hydrating ingredient. Amino acids play a crucial role in wound healing and skin hydration.
This ingredient is also used to help even out skin tone due to its ability to disrupt the melanin production process.
Two structures of phenylalanine exist: L-phenylalanine and D-phenylalanine. L-phenylalanine is essential, this means our bodies cannot produce it naturally and we must get it from foods. Our bodies convert D-phenylalanine to neurotransmitters, and D-phenylalanine is found in our bodies naturally.
Some foods that contain L-phenylalanine include eggs, soybeans, beef, milk.
Learn more about PhenylalanineThreonine is an amino-acid. It helps hydrate the skin and has antioxidant benefits.
Our skin uses threonine for creating collagen and elastin. Humans are not able to create threonine and must get it through eating foods such as fish, lentils, poultry, sesame seeds, and more.
Proline is a non-essential amino acid, meaning your body can make it on its own. In skincare, it is a skin conditioning ingredient that keeps skin soft and hydrated.
It makes up about 23% of the collagen molecule (collagen is the protein responsible for keeping your skin firm) and is involved in your skin's natural hyaluronic acid production. When applied topically, proline can penetrate the skin fairly well due to its small molecular size.
Reviews of this ingredient have found it to be neither a dermal irritant nor a sensitizer.
Fun fact: Proline can be found in protein-rich foods like meat, fish, eggs, and dairy.
Learn more about ProlineValine is an essential amino acid. It is used by our bodies for tissue repair and muscle growth.
An essential amino acid is one in which our bodies cannot naturally produce so we must get them through diet. Foods such as eggs, dairy, red meat, and fish contain valine.
This ingredient can either be derived from an animal product or be synthetically created.
Learn more about ValineIsoleucine is an amino acid that helps reinforce our skin barrier. This amino acid plays a role in creating protein for the body.
Fun fact: Isoleucine is found in meat, fish, dairy, legumes, and nuts.
Histidine is a semi-essential amino acid used by our bodies to create protein. It has humectant and skin conditioning properties.
Our bodies use histidine to create filaggrin - filaggrin is a structural protein that the skin uses in maintaining skin barrier.
One study found histidine and carnosine to be a dynamic duo for your skin:
Oral histidine has also been found to help with filaggrin-deficit skin disorders such as atopic dermatitis.
Why is it considered a semi-essential amino acid? This is because adults are able to create it but children must get it from their diet.
Learn more about HistidineMethionine is an essential amino acid. It is a conditioning agent and commonly found in both skin and hair products.
This amino acid is a precursor to glutathione, a powerful antioxidant.
Fun fact: Methionine can be found in meat, fish, and dairy. It cannot be naturally produce and requires dietary intake.
Learn more about MethionineCysteine is an amino acid found in our bodies. It becomes an antioxidant when converted into gluthatione.
Once it becomes gluthatione, it prevents oxidative damage to parts of our cell. Gluthatione has also been shown to protect our skin from UV-B induced damage.
Collagen extract is derived from parts of animals. It has skin conditioning properties and is mostly comprised of glycine, proline, and hydroxypoline. These are amino acids.
While our skin does have collagen, this ingredient is not used by the skin for anti-aging. Applying collagen topically has not been linked to helping with collagen loss in skin. All the benefits of collagen are related to hydration.
This ingredient will not increase sun sensitivity, but you should always wear sunscreen during the day.
Learn more about Collagen ExtractPotassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.
This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.
Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.
You'll often find this ingredient used with other preservatives.
Learn more about Potassium SorbateReviews
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Where it's from
MEDI-PEEL is a Korean brand
Product acidity level
This product has a PH level of 5.5
Often compared with
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
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