Dr.Melaxin Necksphalt ECM Neck Barrier Ampoule
A ampoule that contains aha, hyaluronic acid, niacinamide, peptides, vitamin c and vitamin e.
Overview
What it is
Ampoule with 48 ingredients that contains AHA, hyaluronic acid, niacinamide, peptides, Vitamin C and Vitamin E
Cool Features
It is reef safe
Suited For
It has ingredients that are good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
It doesn't contain any harsh alcohols, common allergens, oils, parabens, silicones or sulfates
Fun facts
Dr.Melaxin is from South Korea.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
About this product
Ingredients List
Dive into the full list of ingredients.
Water
Skin ConditioningGlycerin
HumectantPropanediol
SolventDipropylene Glycol
MaskingNiacinamide
SmoothingButylene Glycol
Humectant1,2-Hexanediol
Skin ConditioningCellulose Gum
Emulsion StabilisingHydroxyacetophenone
AntioxidantGlycereth-25 PCA Isostearate
EmulsifyingSea Water
HumectantEthylhexylglycerin
Skin ConditioningAdenosine
Skin ConditioningCitric Acid
BufferingTrisodium Ethylenediamine Disuccinate
Parfum
MaskingHyaluronic Acid
HumectantHydrolyzed Hyaluronic Acid
HumectantSodium Hyaluronate
HumectantHydrolyzed Elastin
EmollientSodium Citrate
BufferingAloe Barbadensis Leaf Extract
EmollientDioscorea Japonica Root Extract
Skin ConditioningHibiscus Esculentus Fruit Extract
Skin ConditioningMalva Sylvestris Extract
AstringentAlanine
MaskingGlutamic Acid
HumectantGlycine
BufferingSerine
MaskingThreonine
PCA
HumectantCI 19140
Cosmetic ColorantCaprylic/Capric Triglyceride
MaskingCI 17200
Cosmetic ColorantHydrogenated Lecithin
EmulsifyingPolyglyceryl-10 Oleate
Skin ConditioningHydrogenated Polyisobutene
EmollientSodium Ascorbyl Phosphate
AntioxidantDisodium EDTA
Copper Tripeptide-1
Skin ConditioningPalmitoyl Pentapeptide-4
Skin ConditioningAcetyl Hexapeptide-8
HumectantPalmitoyl Tripeptide-1
Skin ConditioningSh-Polypeptide-3
Skin ConditioningSh-Oligopeptide-1
Skin ConditioningSh-Oligopeptide-2
Skin ConditioningAnemarrhena Asphodeloides Root Extract
Skin ConditioningTocopherol
AntioxidantWater, Glycerin, Propanediol, Dipropylene Glycol, Niacinamide, Butylene Glycol, 1,2-Hexanediol, Cellulose Gum, Hydroxyacetophenone, Glycereth-25 PCA Isostearate, Sea Water, Ethylhexylglycerin, Adenosine, Citric Acid, Trisodium Ethylenediamine Disuccinate, Parfum, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate, Hydrolyzed Elastin, Sodium Citrate, Aloe Barbadensis Leaf Extract, Dioscorea Japonica Root Extract, Hibiscus Esculentus Fruit Extract, Malva Sylvestris Extract, Alanine, Glutamic Acid, Glycine, Serine, Threonine, PCA, CI 19140, Caprylic/Capric Triglyceride, CI 17200, Hydrogenated Lecithin, Polyglyceryl-10 Oleate, Hydrogenated Polyisobutene, Sodium Ascorbyl Phosphate, Disodium EDTA, Copper Tripeptide-1, Palmitoyl Pentapeptide-4, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Sh-Polypeptide-3, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Anemarrhena Asphodeloides Root Extract, Tocopherol
Key Ingredients
Benefits
Concerns
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinPropanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Learn more about PropanediolDipropylene Glycol is a synthetically created stabilizer and solvent. It is a part of the glycol class in the alcohol family.
Dipropylene Glycol helps dissolve and evenly distribute ingredients. It also helps decrease viscosity and thin out texture.
As a masking agent, Dipropylene Glycol can be used to cover the smell of other ingredients. However, it does not have a scent.
Studies show Dipropylene Glycol is considered safe to use in skincare.
Learn more about Dipropylene GlycolNiacinamide has emerged as an all-star ingredient due to its many benefits.
It is known to treat acne by reducing inflammation. It also helps fade dark-spots and strengthen the skin by promoting the growth of the ceramide barrier.
Other benefits include smoothing wrinkles and minimizing redness.
The cherry on top? Niacinamide can also help build keratin, a protein that keeps skin firm.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
Niacinamide can be mixed with other ingredients to boost benefits. For instance, it has shown to be effective when used with copper, folic acid, and zinc to treat acne.
Learn more about NiacinamideButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
- It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
- It is a humectant, which means that it helps attract moisture into the skin.
- It helps improve product application.
- It has mild preservative properties.
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
Cellulose Gum is a water-soluble polymer that comes from cellulose. It is used to change the texture of a product and to help stabilize emulsions.
As an emulsifier, cellulose gum specifically thicken the texture of water-based products.
This ingredient is considered hypoallergenic and non-toxic. Cellulose Gum can be found in cosmetics, food, and other household goods such as paper products.
Learn more about Cellulose GumHydroxyacetophenone is antioxidant with skin conditioning and soothing properties. It also boosts the efficiency of preservatives.
This ingredient is not irritating or sensitizing.
Glycereth-25 PCA Isostearate isn't fungal acne safe.
Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.
Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.
Adenosine has many benefits when used. These benefits include hydrating the skin, smoothing skin, and reducing wrinkles. Once applied, adenosine increases collagen production. It also helps with improving firmness and tissue repair.
Studies have found adenosine may also help with wound healing.
In skincare products, Adenosine is usually derived from yeast.
Learn more about AdenosineCitric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).
As an AHA, Citric Acid removes the top layer of skin cells from the newer layer of skin underneath. This helps skin to remove dark spots and even out skin tone.
If you spot Citric Acid near the end of an ingredient list, it's likely there as a pH adjuster rather than an active ingredient.
Read more about some other popular AHA's here:
Learn more about Citric AcidTrisodium Ethylenediamine Disuccinate is used to help stabilize a product.
It is a chelating agent, meaning it helps prevent metal ions from binding to other ingredients. This prevents unwanted reactions in products. Metal ions can come into a product via the water ingredient. They are found in trace amounts and are not known to be harmful.
Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.
Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.
For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.
The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.
For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.
One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.
Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.
Parfum can also be used to mask or cover an unpleasant scent.
The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.
Learn more about ParfumHyaluronic acid is naturally found in healthy skin. It is a humectant, meaning it draws moisture to your skin.
This ingredient helps hydrate, soothe, and protect the skin.
What makes hyaluronic acid so hydrating? It has the capacity to bind or hold large amounts of water.
Fun fact: It is already naturally found in our bodies, such as the fluids of our eyes and our joints.
Studies find this ingredient to have anti-inflammatory and anti-microbial properties. This can help speed up wound-healing.
Hyaluronic acid can be irritating if the molecule has a low-molecular weight, or if the molecules are small.
One study found low-molecular weight hyaluronic acid to be pro-inflammatory, meaning some people may experience irritation. This is because our bodies use hyaluronic acid in the wound-healing process to signal to our bodies, via irritation, that something needs healing.
The same study found high-molecular weight hyaluronic acid to be anti-inflammatory.
These are some other common types of Hyaluronic Acid:
Learn more about Hyaluronic AcidHydrolyzed Hyaluronic Acid is a form of hyaluronic acid. It is created by the hydrolysis of hyaluronic acid with a high molecular weight. Once created, Hydrolyzed Hyaluronic Acid has a low molecular weight.
Low molecular weight HA has been shown to hydrate and increase elasticity of the skin. Increasing elasticity is also associated with reduction of wrinkle depth.
One study found topical low molecular weight hyaluronic acid may be considered for the treatment of rosacea in the adult population. However, we always recommend speaking with a professional about your skin concerns.
Hyaluronic acids are a humectant. This means they draw moisture from the air. Hyaluronic acids help moisturize, soothe, and protect the skin.
Read more about other common forms of hyaluronic acid:
Learn more about Hydrolyzed Hyaluronic AcidSodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.
Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.
Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.
These are some other common types of Hyaluronic Acid:
Learn more about Sodium HyaluronateWe don't have a description for Hydrolyzed Elastin yet.
Sodium Citrate is the sodium salts of citric acid. In skincare, it is used to alter pH levels and acts as a preservative.
Its main functions are to maintain the pH of a product and neutralize metal ions.
The acidity of our skin is maintained by our glands and skin biome; normal pH level of skin is slightly acidic (~4.75-5.5).
Being slightly acidic allows our skin to create an "acid mantle". This acid mantle is a thin barrier that protects our skin from bacteria and contaminants.
Learn more about Sodium CitrateAloe Barbadensis Leaf Extract is an extract of the leaves of the aloe, Aloe barbadensis, Liliaceae.
You may know Aloe to be a good sunburn reliever and inflammation reducer. This is because it contains many components that are known to help reduce irritation and itchiness. These include vitamins, amino acids, polysaccharides, and more. The high water content of aloe also helps give a cooling effect.
Aloe contains the antioxidants Vitamins A, C, and E. These vitamins neutralize free radicals. Free-radicals are molecules that may damage your skin cells, such as pollution.
The aloe plant is naturally abundant in polysaccharides, a carbohydrate made of sugar molecules. Polysaccharides help hydrate your skin by mimicking your skin's natural carbohydrates.
As it is easily absorbed by the skin, aloe is a great moisturizer. It is both a humectant and emollient. Emollients help trap moisture in your skin, keeping your skin soft. Humectants draw water from the air to your skin.
Other components of aloe include sugars such as monosaccharides and polysaccharides, folic acid, choline, many common minerals such as calcium, fatty acids, amino acids, and Vitamin B12.
Aloe does not protect against UV rays, despite it soothing sunburns.
There are over 420 species of aloe but Aloe Barbadensis is the most commonly used for topical products.
Learn more about Aloe Barbadensis Leaf ExtractDioscorea Japonica Root Extract comes from the Asian Mountain Yam. It contains antioxidant and anti-inflammatory properties.
Antioxidants help neutralize free-radical molecules. These molecules may damage your skin cells and DNA.
We don't have a description for Hibiscus Esculentus Fruit Extract yet.
We don't have a description for Malva Sylvestris Extract yet.
Alanine is an amino acid and is already found in the human body. Our skin uses alanine to build collagen, elastin, and keratin.
Glutamic Acid is an amino acid that is found in all living organisms. Our bodies use this to help nerve cells in the brain communicate with other cells.
In cosmetics, glutamic acid is a famous humectant. It draws water from the air to your skin, keeping your skin hydrated (like hyaluronic acid).
An in-vitro study from 2024 found glutamic acid to play a role in inhibiting inflammation and thus a potential skin-soothing ingredient.
Other studies show it to be have potential wound healing, skin barrier repair, and hair growth properties.
Glutamic acid has poor solubility in water and other solvents.
Learn more about Glutamic AcidThis ingredient is an amino acid that helps build proteins and moisturizes skin. It is already present in our skin as our bodies produce them naturally.
Glycine already plays a role in helping keep our skin moisturized as amino acids transport moisture throughout our skin.
As collagen is made up of glycine and other amino acids, it is believed glycine may help our skin produce more collagen.
Learn more about GlycineSerine is an amino acid naturally found in our body. Our bodies use amino acids to create protein.
Amino-acids help give keep our skin hydrated. They play an important role in the skin barrier, which keeps the skin plump and firm.
Serine is a non-essential amino acid, meaning we don't need to obtain it from eating foods.
Learn more about SerineThreonine is an amino-acid. It helps hydrate the skin and has antioxidant benefits.
Our skin uses threonine for creating collagen and elastin. Humans are not able to create threonine and must get it through eating foods such as fish, lentils, poultry, sesame seeds, and more.
PCA is derived from amino acids and is naturally found in our skin's barrier.
As a humectant, PCA helps draw and hold moisture to the skin. Studies show it is effective at helping the skin stay hydrated long-term.
CI 19140 is also known as Tartrazine. Tartrazine is a synthetic dye used in cosmetics, foods, and medicine to add a yellow color.
Tartrazine is created from petroleum and is water-soluble.
Some people may experience allergies from this dye, especially asthmatics and those with an aspirin intolerance.
Learn more about CI 19140This ingredient is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.
It helps thicken a product's formula and makes it easier to spread by dissolving clumping compounds.
Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this.
Learn more about Caprylic/Capric TriglycerideCi 17200 is a synthetic reddish-purple dye.
Hydrogenated Lecithin is created from the hydrogenation of lecithin (a group of phospholipids). Hydrogenation is a chemical reaction between hydrogen and another element.
This ingredient is an emollient and emulsifier. As an emollient, it helps soften skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.
Polyglyceryl-10 Oleate isn't fungal acne safe.
Hydrogenated Polyisobutene is a synthetic polymer. Polymers are compounds with high molecular weight. Hydrogenated Polyisobutene is an emollient and texture enhancer.
In one study, Hydrogenated Polyisobutene showed better skin hydration levels than Caprylic/Capric Triglyceride. As an emollient, it helps keep your skin soft and hydrated by trapping moisture in.
Hydrogenated Polyisobutene is often used as a mineral oil replacement.
Learn more about Hydrogenated PolyisobuteneSodium Ascorbyl Phosphate is a form of Vitamin C. It is the salt of ascorbic acid.
This ingredient is more gentle than ascorbic acid. It is also more stable when exposed to light and oxygen.
Vitamin C helps reduce redness, improve skin texture, reduce the effects of aging, reduce the visibility of dark spots, and brighten skin.
Your skin uses Vitamin C to produce collagen and collagen production plays a role in having a strong skin barrier and plump skin. As an antioxidant, this ingredient also helps reduce the signs of aging such as fine-lines and wrinkles.
VItamin C helps brighten skin by blocking the process of skin darkening.
In a 2011 study, Sodium Ascorbyl Phosphate was found to have antibacterial properties. This may help treat acne.
Read more about other types of Vitamin C:
Learn more about Sodium Ascorbyl PhosphateDisodium EDTA plays a role in making products more stable by aiding other preservatives.
It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.
Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.
Learn more about Disodium EDTACopper Tripeptide-1 is a peptide naturally found in body fluids. Peptides are building blocks for protein.
Studies show this ingredient tells our body to create more collagen and elastin. Collagen is a protein that makes connective tissue. Elastin is the protein responsible for giving our skin elasticity. Our bodies start to slow down collagen and elastin production with age.
Boosting collagen and elastin production can help create a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin. It's a win-win situation!
This ingredient helps with scar healing. This is because it breaks down damaged collagen, the main component of scar tissue. It may also help with reducing sunspots, acne scars, and uneven skin tone.
On top of all this, Copper Tripeptide-1 is also an antioxidant. Antioxidants help the body fight off free-radicals. Free radicals are molecules that damage our cells, such as pollution and tobacco smoke.
More benefits: Copper Tripeptide-1 helps maintain tissues in blood vessels and promote natural hyaluronic acid in skin.
Read more about other common types of peptides here:
Learn more about Copper Tripeptide-1You might know this ingredients as Matrixyl, a famous peptide.
Peptides are building blocks for protein. Palmitoyl Pentapeptide-4 consists of five amino acids. These amino acids include: 2 lysines, 2 threonines, and serine
This ingredients tells our body to create more collagen. Collagen is a protein that makes connective tissue. Boosting collagen production leads to a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin.
Thus, Matrixyl may help improve the look of wrinkles.
Read more about other common types of peptides here:
Learn more about Palmitoyl Pentapeptide-4Acetyl Hexapeptide-8 is a peptide. A common name for this peptide is Argireline.
Argireline has a similar function to botox; it prevents muscle movement and contractions slightly. By preventing muscles from moving, argireline also prohibits the formation of fine lines and wrinkles. However, research is lacking in proving this ingredient to be as effective as botox.
On the other hand, argireline tells our body to create more collagen. Collagen is a protein that makes connective tissue. Boosting collagen production leads to a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin.
Read more about other common types of peptides here:
Learn more about Acetyl Hexapeptide-8Palmitoyl Tripeptide-1 is a 3-amino acid peptide. Peptides are building blocks for protein.
This ingredient is a signal peptide, meaning it tells our skin to create collagen. Collagen is a protein that makes connective tissue. Boosting collagen production leads to a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin.
Palmitoyl Tripeptide-1 can help reduce wrinkles and make the skin look more youthful.
Read more about other common types of peptides here:
Learn more about Palmitoyl Tripeptide-1Sh-Polypeptide-3 is a peptide.
sh-Oligopeptide-1 is a peptide found naturally in our bodies. Peptides are the building blocks for collagen and elastin in our skin.
In cosmetics, this ingredient is bioengineered to be identical to a human gene that codes for epidermal growth factor (EGF). EGF are signal molecules that simulate cell growth and healing.
Studies find EGF help with:
In South Korea and China, EGF is considered a controversial ingredient. The South Korean Ministry of Food and Drug Safety has cracked down on companies with products including EGF due to false advertisement claims.
According to Dr. Zoe Draelos, growth factors have some drawbacks:
There is also controversy surrounding growth factors. The controversy is due to their mitogenic activity, or their ability to increase the number of cells. It is best to avoid using growth factors if you have psoriasis or are at risk of skin cancer. However, it should be noted EGF are not mutagenic - meaning they will not cause cancer.
Learn more about Sh-Oligopeptide-1This peptide has similar properties to Sh-Oligopeptide-1.
In cosmetics, this ingredient is bioengineered to be identical to a human gene that codes for epidermal growth factor (EGF). EGF are signal molecules that simulate cell growth and healing.
There is also controversy surrounding EGF. The controversy is due to their mitogenic activity, or their ability to increase the number of cells. It is best to avoid using growth factors if you have psoriasis or are at risk of skin cancer. However, it should be noted EGF are not mutagenic - meaning they will not cause cancer.
Learn more about Sh-Oligopeptide-2This ingredient is more commonly known as Zhi Mu root. You might see this ingredient listed under 'Volufiline' products.
That's because 'Volufiline' is comprised of this ingredient and Hydrogenated Polyisobutene.
Zhi Mu root is rich in sarsasapogenin. This compound has anti-inflammatory and soothing properties.
It is commonly used in East Asian medicine.
Learn more about Anemarrhena Asphodeloides Root ExtractTocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.
Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.
Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.
You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.
There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.
Learn more about TocopherolReviews
No written reviews yet. Be the first to review this product.
Where it's from
Dr.Melaxin is a Korean brand
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about us· Updated April 9, 2025 • Added by reginasheynblat