Depology Cica Ceramide Barrier-Boosting Cleanser
A face cleanser with 42 ingredients, including vitamin E, hyaluronic acid, and ceramides.
Overview
What it is
Face cleanser with 42 ingredients that contains ceramides, hyaluronic acid and Vitamin E
Cool Features
It is cruelty-free, fungal acne (malassezia) safe, and reef safe
Suited For
It has ingredients that are good for anti aging, dry skin, brightening skin, sensitive skin, scar healing and better texture
Free From
It doesn't contain any harsh alcohols, common allergens, fragrances, parabens, silicones or sulfates
Fun facts
Depology is from South Korea. This product is used in 7 routines created by our community.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside
Ingredients List
Water
Skin ConditioningGlycerin
HumectantDisodium Cocoamphodiacetate
CleansingCoco-Betaine
CleansingSodium Chloride
MaskingLauryl Hydroxysultaine
CleansingSodium Cocoyl Alaninate
Surfactant1,2-Hexanediol
Skin ConditioningBetaine
HumectantAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingLauryl Betaine
CleansingButylene Glycol
HumectantDisodium Cocoyl Glutamate
CleansingHydroxypropyl Starch Phosphate
Hexylene Glycol
EmulsifyingRosmarinus Officinalis Leaf Oil
MaskingTocopheryl Acetate
AntioxidantCentella Asiatica Extract
CleansingEthylhexylglycerin
Skin ConditioningViola Mandshurica Flower Extract
AntioxidantGardenia Florida Fruit Extract
Skin ConditioningCaramel
Cosmetic ColorantSodium Hyaluronate
HumectantCaprylic/Capric Triglyceride
MaskingPhosphatidylcholine
EmulsifyingHyaluronic Acid
HumectantCeramide NP
Skin ConditioningMadecassoside
AntioxidantAsiaticoside
AntioxidantCoptis Chinensis Root Extract
AntioxidantDisodium EDTA
Cucumis Sativus Fruit Extract
EmollientGlycine
BufferingMadecassic Acid
Skin ConditioningAsiatic Acid
Skin ConditioningGlutamic Acid
HumectantSerine
MaskingLysine
Skin ConditioningAlanine
MaskingArginine
MaskingThreonine
Proline
Skin ConditioningWater, Glycerin, Disodium Cocoamphodiacetate, Coco-Betaine, Sodium Chloride, Lauryl Hydroxysultaine, Sodium Cocoyl Alaninate, 1,2-Hexanediol, Betaine, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Lauryl Betaine, Butylene Glycol, Disodium Cocoyl Glutamate, Hydroxypropyl Starch Phosphate, Hexylene Glycol, Rosmarinus Officinalis Leaf Oil, Tocopheryl Acetate, Centella Asiatica Extract, Ethylhexylglycerin, Viola Mandshurica Flower Extract, Gardenia Florida Fruit Extract, Caramel, Sodium Hyaluronate, Caprylic/Capric Triglyceride, Phosphatidylcholine, Hyaluronic Acid, Ceramide NP, Madecassoside, Asiaticoside, Coptis Chinensis Root Extract, Disodium EDTA, Cucumis Sativus Fruit Extract, Glycine, Madecassic Acid, Asiatic Acid, Glutamic Acid, Serine, Lysine, Alanine, Arginine, Threonine, Proline
Key Ingredients
Benefits
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinDisodium Cocoamphodiacetate is a surfactant and helps cleanse skin. It is created from the fatty acids of coconut oil.
Surfactants help rinse oil, dirt, and other pollutants easily from skin. It has a faint fruit-like scent.
Coco-Betaine is the natural version of Cocamidopropyl Betaine. It is often derived from coconuts.
Coco-Betaine is a surfactant, meaning it helps remove dirt and oil from the skin.
Chances are, you eat sodium chloride every day. Sodium Chloride is also known as table salt. This ingredient has many purposes in skincare: thickener, emulsifier, and exfoliator.
You'll most likely find this ingredient in cleansers where it is used to create a gel-like texture. As an emulsifier, it also prevents ingredients from separating.
You might see people debate whether Sodium Chloride is comedogenic, but there actually haven't been any comedogenic tests done on it. Either way, the overall formulation of a product matters a lot more than any single ingredient.
You might see this ingredient used in scrubs as a primary exfoliating ingredient.
Learn more about Sodium ChlorideLauryl Hydroxysultaine is a mild surfactant or cleansing ingredient that helps lift away dirt/oil, boost foam, and thicken the formula. It plays nicely with other surfactants and stays stable across a wide pH range.
This ingredient is a surfactant and foam producer.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.ย
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservativesย
Betaine is a humectant. Like hyaluronic acid, it helps attract and retain moisture in the skin. Itโs known for being gentle and for helping the skin maintain balanced hydration.
Betaine is mainly used to improve hydration and support calmer skin. It helps skin cells regulate water balance because it functions as an osmolyte.
Some studies suggest betaine may support making skin tone more even.
Fun fact: Betaine naturally exists in the skin and the body. In cosmetic products, it can be either plant-derived (most commonly from sugar beets) or synthetically produced for consistency and stability.
Betaine is also known as trimethylglycine.
Learn more about BetaineAcrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products.
As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied.
It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin.
A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record.
Learn more about Acrylates/C10-30 Alkyl Acrylate CrosspolymerLauryl Betaine is a cleansing ingredient. You'll most likely see it in face washes, body washes, and shampoos. It's a type of surfactant that helps water mix with oil so dirt, sweat, and sunscreen can rinse off easily.
Chemically, lauryl betaine is an amphoteric surfactant so it carries both a positive and negative charge. This helps it create a creamy foam while being less harsh than stronger detergent-type cleansers.
According to CIR, this ingredient is generally considered safe when used in cosmetics. However, like all surfactants, it can be irritating when used in high amounts of in formulas that aren't well balanced.
Learn more about Lauryl BetaineButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolWe don't have a description for Disodium Cocoyl Glutamate yet.
Hydroxypropyl Starch Phosphate is a modified starch used to help thicken a product.
It is also used in foods.
Hexylene Glycol is a multitasker ingredient that works as a solvent, humectant, emulsifier, viscosity reducer, and preservative booster.
It is able to dissolve both water and oil-soluble ingredients to stabilize tricky actives and make products spread more easily.
As a humectant, it pulls water into the skin. But it's a pretty minor moisturizing ingredient compared to other humectants, like glycerin.
Interestingly, it can act as a mild penetration enhancer. One in vitro study on human skin found a 12% concentration upped the absorption of mometasone furoate (a medicinal ingredient used to treat inflammatory skin conditions) up to 7%.
This ingredient is typically used at levels of 0.1-10% depending on the role it's playing.
A patch test study on eczema patients didn't find a significant increase in irritation versus the control group, but the potential for irritation rises at higher concentrations.
Learn more about Hexylene GlycolRosmarinus Officinalis Leaf Oil is an essential oil also known as rosemary essential oil. In skincare, it is a skin conditioning agent and also acts as a natural fragrance that gives products a fresh/herby smell.
The oil is a mix of over 100 volatile compounds with 1,8-cineole, ฮฑ-pinene, camphor, and verbenone usually leading the pack.
Lab studies credit this oil with antioxidant, anti-inflammatory, and antimicrobial activity. Some research even show rosemary compounds calming acne-related inflammation.
The Cosmetic Ingredient Review (CIR) has concluded rosemary-derived ingredients to be safe when formulated to be nonsensitizing.
Since this is a fragrant essential oil, the main concern is for fragrance-sensitive folks.
Learn more about Rosmarinus Officinalis Leaf OilTocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.
Tocopheryl Acetate is commonly found in both skincare and dietary supplements.
Learn more about Tocopheryl AcetateCentella Asiatica Extract (Centella) is derived from an herb native to Southeast Asia. It is famous for its anti-inflammatory and soothing properties.
Centella is rich in antioxidants and amino acids, such as Madecassic Acid and Asiaticoside.
Studies show the compounds in centella help with:
The combination of all these properties makes centella effective at soothing, hydrating, and protecting the skin.
Other great components of centella include Vitamin A, vitamin C, several B vitamins, and Asiatic Acid.
Fun fact: Centella has been used as a medicine and in food for many centuries. As a medicine, it is used to treat burns, scratches, and wounds.
Learn more about Centella Asiatica ExtractEthylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinThis extract comes from the petals of the manchurian violet, a plant native to East Asia. It has astringent and antioxidant properties.
This ingredient comes from the evergreen flowering plant, gardenia. It has skin conditioning properties.
We don't have a description for Caramel yet.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Learn more about Sodium HyaluronateCaprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredientโs final chemical composition and not its marketing name or source.
This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.
Learn more about Caprylic/Capric TriglyceridePhosphatidylcholine (PC) is a type of phospholipid, a class of molecule that makes up our own cell membranes.
It has a glycerol backbone, two fatty acid tails (mostly linoleic, palmitic, and oleic), and a phosphate-choline head group.
In skincare, PC pulls double duty:
The linoleic acid it carries gets incorporated into skin ceramides and helps reinforce the lipid matrix.
Interestingly, it can help top of the omega-6 fatty acid that's often low in acne-prone and atopic skin. There's a sizeable body of literature that supports its use in dry, barrier-impaired, and breakout-prone skin.
There are two kinds of PC you'll see on ingredient lists.
Use levels range from <1% as a liposomal carrier and between 20-40% in lamellar matrix sytems.
Learn more about PhosphatidylcholineHyaluronic acid (HA) is a glycosaminoglycan (basically a long sugar chain) that your skin already makes on its own. In your skin, HA lives in the extracellular matrix and acts as the body's moisture reservoir.
Topically, HA is a humectant that binds water and helps skin look more plump, smooth, and hydrated.
The only catch is that HA isn't a single thing; it actually comes in a wide range of molecular weights (~50 - 2,000+ kDA) and size matters.
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
This is why the best HA serums blend the two sizes together so you get the best of both worlds.
The majority of cosmetic HA is produced by bacterial fermentation, typically using Streptococcus or Bacillus strains. Typical use levels in skincare sit around 0.1-2%.
A clinical study using a 0.2% low-molecular weight HA gel showed improvement in facial seborrheic dermatitis with excellent tolerance.
These are some other common types of Hyaluronic Acid:
Learn more about Hyaluronic AcidCeramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.
Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.
This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.
A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.
Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.
Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.
Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.
Learn more about Ceramide NPMadecassoside is one of four active compounds found in Centella asiatica and is one of the main reasons Centella is so effective at calming irritated skin and supporting the moisture barrier.
There's a solid body of peer-reviewed research backing Madecassoside for several skin benefits. Studies have found:
Madecassoside pairs well with other hydrating or antioxidant ingredients like Ascorbic Acid or Hyaluronic Acid.
Learn more about MadecassosideAsiaticoside comes from the super popular skin-soothing ingredient, Centella asiatica. It's the reason centella-based products have a strong reputation for repairing and calming skin, along with its sibling compound Madecassoside.
Research from 2016-2025 supports its role in:
You'll usually find this in concentrations between 0.2-5%.
Learn more about AsiaticosideCoptis Chinensis Root Extract is also known as huanglian or Chinese goldthread. It is a plant extract with soothing and antioxidant properties.
This plant naturally contains berberine, a compound that lab studies suggest can help "turn down" inflammation signals and oxidative stress, and make it harder for certain microbes to thrive. While topical berberine research does support anti-inflammatory potential in dermatitis-like models, most of the stronger evidence is preclinical.
That's why you'll frequently see this ingredient in formulations aimed at redness, blemish-prone skin, or sensitive skin.
A small human photopatch study reported that "coptis" at 5% did not trigger photoallergic/photosensitive reactions in the tested group. Like other botanical extracts, it may cause allergies in some. Be sure to patch test if you're weary.
Learn more about Coptis Chinensis Root ExtractDisodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Learn more about Disodium EDTAThis extract comes from cucumber. Cucumbers are mostly made up of water (95%), and the other 5% is composed of: vitamin C, caffeic acid, fatty acids, amino acids, and other minerals.
Cucumbers have anti-inflammatory, barrier repair, and hydrating properties.
They contain shikimate dehydrigenase, an enzyme shown to help reduce inflammation and soothe the skin.
The amino acids found in cucumbers help nourish our skin's natural acid mantle (it's an important part of our skin barrier). This slightly acidic film acts as a barrier to protect us from bacteria, viruses, and other contaminants.
Unless you have an allergy to cucumbers, this is generally a non-irritating ingredient.
Fun fact: Cucumis Sativus is native to South Asia and can now be found on every continent.
Learn more about Cucumis Sativus Fruit ExtractGlycine is the smallest amino acid and a key building block of collagen. It's part if your skin's Natural Moisturizing Factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
A study from 2022 found that an amino acid complex featuring taurine, arginine, and glycine significantly reduced skin irritation, improved redness, and accelerated the skin repair process.
Madecassic Acid is a major component of Centella Asiatica Extract. It has anti-inflammatory and antioxidant properties.
It is a triterpenoid, meaning it naturally acts as an antioxidant. Antioxidants protect your skin against damage from environmental factors such as pollution and UV.
Studies show Madecassic Acid helps soothe the skin due to its ability to block inflammation pathways.
Learn more about Madecassic AcidAsiatic Acid is a major component of Centella Asiatica Extract. It has wound-healing, anti-inflammatory, and antioxidant properties.
Studies show Asiatic Acid is able to block the pathway for skin inflammation receptors, helping to soothe skin.
As an antioxidant, asiatic acid helps protect our skin against damaging environmental factors.
Learn more about Asiatic AcidGlutamic Acid is an amino acid that is found in all living organisms. Our bodies use this to help nerve cells in the brain communicate with other cells.
In cosmetics, glutamic acid is a famous humectant. It draws water from the air to your skin, keeping your skin hydrated (like hyaluronic acid).
An in-vitro study from 2024 found glutamic acid to play a role in inhibiting inflammation and thus a potential skin-soothing ingredient.
Other studies show it to be have potential wound healing, skin barrier repair, and hair growth properties.
Glutamic acid has poor solubility in water and other solvents.
Learn more about Glutamic AcidSerine is a non-essential amino acid (your body makes it on its own!). It is a major player in your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
Serine is one of your NMF's most abundant components that works as a skin-identical humectant. Its hydroxyl group grabs onto water molecules to boost hydration without any heaviness or occlusion.
Research on a hydrogel with serine confirmed this serine got delivered to your stratum corneum and demonstrated enhanced skin moisturization.
Interestingly serine also helps your skin produce filaggrin, a protein that keeps your skin barrier strong and used to create collagen.
Learn more about SerineLysine is an essential amino acid (your body cannot make it on its own). It has skin conditioning properties and one of the key players in collagen synthesis.
When your body creates collagen, lysine is basically the glue that holds everything together. It helps collagen fibers lock into each other and stay strong, with vitamin C being its trusty sidekick. Without enough lysine, this glue gets flimsy and less firm, resulting in less bouncy skin.
In skincare, lysine is mostly there to help keep your skin moisturized. It carries water through your skin's layers so everything stays plump.
So will putting lysine on your face create bouncier skin?
It's hard to say; most of the exciting collagen research on lysine comes from oral supplements or lab studies on mice. Further research is needed to truly understand what role topical lysine plays in skincare and your skin.
However, there's no harm in adding lysine to your routine as a supportive and hydrating ingredient.
Learn more about LysineAlanine is an amino acid and is already found in the human body. Our skin uses alanine to build collagen, elastin, and keratin.
Arginine is a semi-essential amino acid. This just means our bodies can product a bit on its own, but sometimes needs a little boost from food sources.
It is a part of your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
Here's an interesting thing about Arginine: your skin converts it into urea through the Krebs-Henseleit urea cycle. Urea is one of the most effective humectants your skin naturally produces.
A clinical study showed applying 2.5% arginine hydrochloride to atopic dermatitis skin showed significant urea levels in the stratum corneum and improved moisture in just four weeks.
Arginine is also a precursor to nitric oxide; nitric oxide improves microcirculation and supports wound healing and collagen synthesis.
One study found that an amino acid complex containing Arginine reduced skin irritation, improved hydration, and accelerated skin repair in clinical / in-vivo studies.
Arginine itself is an amino acid and not a fatty acid, oil, or ester. On its own, it's not a direct food source for Malassezia, or the yeast that causes fungal acne.
Learn more about ArginineThreonine is an amino-acid. It helps hydrate the skin and has antioxidant benefits.
Our skin uses threonine for creating collagen and elastin. Humans are not able to create threonine and must get it through eating foods such as fish, lentils, poultry, sesame seeds, and more.
Proline is a non-essential amino acid, meaning your body can make it on its own. In skincare, it is a skin conditioning ingredient that keeps skin soft and hydrated.
It makes up about 23% of the collagen molecule (collagen is the protein responsible for keeping your skin firm) and is involved in your skin's natural hyaluronic acid production. When applied topically, proline can penetrate the skin fairly well due to its small molecular size.
Reviews of this ingredient have found it to be neither a dermal irritant nor a sensitizer.
Fun fact: Proline can be found in protein-rich foods like meat, fish, eggs, and dairy.
Learn more about ProlineReviews
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Depology is a Korean brand
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The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about usยท Updated October 30, 2024 • Added by emmalyneschutt