Versus

ZO Skin Health Daily Power Defense Versus ZO Skin Health Hydrating Crème

Day Moisturizer
General Moisturizer
American Brand United States
American Brand United States

Updated on January 27, 2025

Overview

Cool Features

They both contain peptides, retinoid and Vitamin E

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture

Free From

They both do not contain any sulfates

What's Inside

They both contain common allergens, fragrances, oils and silicones

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

About this product

About this product

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Daily Power Defense

Water

Skin Conditioning

Cetearyl Isononanoate

Emollient

Cyclopentasiloxane

Emollient
Silicon Icon

Cyclohexasiloxane

Emollient
Silicon Icon

Pentylene Glycol

Skin Conditioning

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Emollient, Skin Conditioning, Solvent

Cyclopentasiloxane, or D5, is a silicone used to improve texture of products and trap moisture.

D5 is considered lightweight and volatile. Volatile means it evaporates quickly after application. Once evaporated, D5 leaves a thin barrier that helps keep skin hydrated.

It is also an emollient. Emollients help soften the skin and prevent water loss. Silicones create a silky texture in products. D5 helps other ingredients become more spreadable.

Studies show D5 is safe to use in skincare products. We recommend speaking with a skincare professional if you have concerns.

Learn more about Cyclopentasiloxane
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

  • It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
  • It is a humectant, which means that it helps attract moisture into the skin.
  • It helps improve product application.
  • It has mild preservative properties.

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Skin Conditioning

Beta-Glucan is a polysaccharide. It can be derived from the cell walls of seaweed, oats, yeast, and fungi. It hydrates the skin and helps boost your skin's natural barrier.

As an antioxidant, beta-glucan helps fight free-radicals. Free-radicals are molecules that may damage your skin cells, such as pollution.

Studies show this ingredient may be an effective wrinkle reducer as it can deeply penetrate into skin. It has also been show to help with wound healing.

Learn more about Beta-Glucan
Skin Conditioning

Retinyl palmitate is a form of retinoid. Retinoids are the superstar class of anti-aging ingredients that include tretinoin and retinol.

This particular ingredient has had a bumpy year with its rise and fall in popularity.

First, Retinyl palmitate is created from palmitic acid and retinol. It is a retinol ester and considered one of the weaker forms of retinoid.

This is because all retinoids have to be converted to Tretinoin, AKA retinoic acid. Retinyl Palmitate is pretty far down the line and has to go through multiple conversions before its effects are seen.

Due to this long and ineffective conversion line, the benefits of Retinyl Palmitate are debated.

Studies show Retinyl Palmitate to help:

Dermatologists say this ingredient is ineffective because it isn't used in high enough concentrations in cosmetics.

This ingredient used to be found in sunscreens to boost the efficacy of sunscreen filters.

The downfall of Retinyl Palmitate was due to released reports about the ingredient being correlated to sun damage and skin tumors.

While there is a study showing this ingredient to cause DNA damage when exposed to UV-A, there is no concrete proof of it being linked to skin cancer. It is safe to use when used correctly.

All retinoids increase your skin's sensitivity to the sun in the first few months of usage. Be especially careful with reapplying sunscreen when using any form of retinoid.

Currently, this ingredient is still allowed in cosmetics all over the world. In Canada, cosmetics must have a warning label stating the product to contain Retinyl Palmitate

Fun fact: This ingredient is often added to low-fat milk to increase the levels of Vitamin A.

Learn more about Retinyl Palmitate
Antioxidant, Skin Conditioning

Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.

One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.

Tocopheryl Acetate is commonly found in both skincare and dietary supplements.

Learn more about Tocopheryl Acetate

When to use

174 Routines
62% use in am
38% use in pm
98% use every day
When to use See routines that use it ->
48 Routines
42% use in am
58% use in pm
90% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

ZO Skin Health Daily Power Defense 51 ingredients

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ZO Skin Health Hydrating Crème 23 ingredients

5.0 /5
from 1 rating