REN Clean Skincare EVERCALM Redness Relief Serum Versus Biologique Recherche Sérum Biosensible Soothing Facial Serum
This calming serum is formulated around Albatrellus Confluens Extract and Laminaria Ochroleuca Extract to calm redness.
This calming serum is formulated around Palmitoyl Tripeptide-8 to calm redness.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningCaprylic/Capric Triglyceride
MaskingGlycerin
HumectantPropanediol
SolventCoco-Caprylate/Caprate
EmollientSqualane
EmollientCetyl Alcohol
EmollientCetyl Phosphate
EmulsifyingCrambe Abyssinica Seed Oil
Skin ConditioningArginine
MaskingGlycine Soja Oil
EmollientGlyceryl Stearate
EmollientPhenoxyethanol
PreservativeSodium Dehydroacetate
PreservativeEthylhexylglycerin
Skin ConditioningInulin
Skin ConditioningVaccinium Vitis-Idaea Seed Oil
AntioxidantSclerotium Gum
Emulsion StabilisingTocopherol
AntioxidantSodium Hyaluronate
HumectantAlbatrellus Confluens Extract
HumectantAlpha-Glucan Oligosaccharide
CleansingXanthan Gum
EmulsifyingSodium Carboxymethyl Betaglucan
Biosaccharide Gum-4
Skin ConditioningLaminaria Ochroleuca Extract
Skin ConditioningCitrus Aurantium Amara Flower Extract
RefreshingBeta-Carotene
Skin ConditioningXanthophylls
Skin ConditioningHelianthus Annuus Seed Oil
EmollientRosmarinus Officinalis Leaf Extract
AntimicrobialCitric Acid
BufferingLactic Acid
BufferingSodium Hydroxide
BufferingGeraniol
PerfumingLinalool
PerfumingWater, Caprylic/Capric Triglyceride, Glycerin, Propanediol, Coco-Caprylate/Caprate, Squalane, Cetyl Alcohol, Cetyl Phosphate, Crambe Abyssinica Seed Oil, Arginine, Glycine Soja Oil, Glyceryl Stearate, Phenoxyethanol, Sodium Dehydroacetate, Ethylhexylglycerin, Inulin, Vaccinium Vitis-Idaea Seed Oil, Sclerotium Gum, Tocopherol, Sodium Hyaluronate, Albatrellus Confluens Extract, Alpha-Glucan Oligosaccharide, Xanthan Gum, Sodium Carboxymethyl Betaglucan, Biosaccharide Gum-4, Laminaria Ochroleuca Extract, Citrus Aurantium Amara Flower Extract, Beta-Carotene, Xanthophylls, Helianthus Annuus Seed Oil, Rosmarinus Officinalis Leaf Extract, Citric Acid, Lactic Acid, Sodium Hydroxide, Geraniol, Linalool
Actinidia Chinensis Fruit Water
MaskingWater
Skin ConditioningPentylene Glycol
Skin ConditioningButylene Glycol
HumectantGlycerin
HumectantXylitylglucoside
HumectantHamamelis Virginiana Water
AstringentAnhydroxylitol
HumectantXylitol
HumectantPueraria Lobata Root Extract
HumectantMimosa Tenuiflora Bark Extract
Skin ProtectingPhenoxyethanol
PreservativeBiosaccharide Gum-2
Skin ConditioningMilk Protein
Skin ConditioningSodium Hyaluronate
HumectantCamellia Sinensis Leaf Extract
AntimicrobialLactose
HumectantLactic Acid
BufferingVaccinium Oxycoccos Fruit Extract
Skin ConditioningSodium Dehydroacetate
PreservativeDisodium Acetyl Glucosamine Phosphate
Skin ConditioningCurcuma Longa Root Extract
AntioxidantCaffeyl Glucoside
AntioxidantSorbic Acid
PreservativePotassium Sorbate
PreservativeDextran
Palmitoyl Tripeptide-8
Skin ConditioningActinidia Chinensis Fruit Water, Water, Pentylene Glycol, Butylene Glycol, Glycerin, Xylitylglucoside, Hamamelis Virginiana Water, Anhydroxylitol, Xylitol, Pueraria Lobata Root Extract, Mimosa Tenuiflora Bark Extract, Phenoxyethanol, Biosaccharide Gum-2, Milk Protein, Sodium Hyaluronate, Camellia Sinensis Leaf Extract, Lactose, Lactic Acid, Vaccinium Oxycoccos Fruit Extract, Sodium Dehydroacetate, Disodium Acetyl Glucosamine Phosphate, Curcuma Longa Root Extract, Caffeyl Glucoside, Sorbic Acid, Potassium Sorbate, Dextran, Palmitoyl Tripeptide-8
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinLactic Acid is another well-loved alpha hydroxy acid (AHA). It is gentler than glycolic acid but still highly effective.
Its main role is to exfoliate the surface of the skin by loosening the “glue” that holds dead skin cells together. Shedding those old cells leads to smoother, softer, and more even-toned skin.
Because lactic acid molecules are larger than glycolic acid, they don’t penetrate as deeply. This means they’re less likely to sting or irritate, making it a great choice for beginners or those with sensitive skin.
Like glycolic acid, it can:
Lactic acid also acts as a humectant (like hyaluronic acid). It can draw water into the skin to improve hydration and also plays a role in the skin's natural moisturizing factor (NMF) in the form of sodium lactate.
Studies show it can boost ceramide production to strengthen the skin barrier and even help balance the skin’s microbiome.
To get results, choose products with a pH between 3-4.
Lower strengths (5-12%) focus on surface exfoliation; higher strengths (12% and up) can reach deeper in the dermis (deeper, supportive layer) to improve skin texture and firmness over time.
Though it was originally derived from milk, most modern lactic acid used in skincare is vegan. It is made through non-dairy fermentation to create a bio-identical and stable form suitable for all formulations.
When lactic acid shows up near the end of an ingredient list, it usually means the brand added just a tiny amount to adjust the product’s pH.
Legend has it that Cleopatra used to bathe in sour milk to help reduce wrinkles.
Lactic acid is truly a gentle multitasker: it exfoliates, hydrates, strengthens, and brightens. It's a great ingredient for giving your skin a smooth, glowing, and healthy look without the harshness of stronger acids.
Read more about some other popular AHA's here:
Learn more about Lactic AcidPhenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Learn more about PhenoxyethanolSodium Dehydroacetate is a synthetic preservative and sodium salt form of dehydroacetic acid. It stops bacteria, mold, and yeast from growing in your products at low concentrations.
Clinical testing found it to be non-irritating, non-sensitizing, and non-photosensitizing. It's also not significantly absorbed through skin.
There are a very small number of reported cases of contact dermatitis in cases linked to wound-care creams used over compromised skin (rather than skincare).
Overall, this is a well-studied and low-risk preservative just doing its job.
Typical concentrations run up to 0.6%, which is also the maximum amount permitted under both EU CosIng regulations and US FDA guidelines.
Learn more about Sodium DehydroacetateSodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Learn more about Sodium HyaluronateWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water