Paula's Choice Skin Recovery Super Antioxidant Concentrate Serum with Retinol Versus Paula's Choice Resist Ultra-Light Super Antioxidant Concentrate Serum
This anti-aging serum is formulated around Tocopherol and Retinol to soften the look of wrinkles and hydrate skin.
This anti-aging serum is formulated around Resveratrol and Niacinamide to soften the look of wrinkles and calm redness.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Cyclopentasiloxane
EmollientDimethicone
EmollientC12-15 Alkyl Benzoate
AntimicrobialOlea Europaea Fruit Oil
MaskingTocopherol
AntioxidantRetinol
Skin ConditioningTetrahexyldecyl Ascorbate
AntioxidantBisabolol
AntioxidantTocotrienols
Skin ConditioningAdenosine
Skin ConditioningTetrahydrodiferuloylmethane
AntioxidantTetrahydrodemethoxydiferuloylmethane
AntioxidantTetrahydrobisdemethoxydiferuloylmethane
AntioxidantCamellia Oleifera Leaf Extract
AstringentVitis Vinifera Seed Oil
EmollientChamomilla Recutita Flower Extract
MaskingArctostaphylos Uva-Ursi Leaf Extract
Skin ConditioningStearyl Dimethicone
EmollientAstaxanthin
Skin ConditioningGlycine Soja Oil
EmollientVitis Vinifera Seed Extract
AntimicrobialOenothera Biennis Oil
EmollientVaccinium Macrocarpon Seed Oil
Skin ConditioningRubus Idaeus Seed Oil
EmollientVaccinium Myrtillus Seed Oil
Skin ConditioningElaeis Guineensis Oil
EmollientSd Alcohol 40
AstringentCyclopentasiloxane, Dimethicone, C12-15 Alkyl Benzoate, Olea Europaea Fruit Oil, Tocopherol, Retinol, Tetrahexyldecyl Ascorbate, Bisabolol, Tocotrienols, Adenosine, Tetrahydrodiferuloylmethane, Tetrahydrodemethoxydiferuloylmethane, Tetrahydrobisdemethoxydiferuloylmethane, Camellia Oleifera Leaf Extract, Vitis Vinifera Seed Oil, Chamomilla Recutita Flower Extract, Arctostaphylos Uva-Ursi Leaf Extract, Stearyl Dimethicone, Astaxanthin, Glycine Soja Oil, Vitis Vinifera Seed Extract, Oenothera Biennis Oil, Vaccinium Macrocarpon Seed Oil, Rubus Idaeus Seed Oil, Vaccinium Myrtillus Seed Oil, Elaeis Guineensis Oil, Sd Alcohol 40
Water
Skin ConditioningCyclopentasiloxane
EmollientButylene Glycol
HumectantDimethicone
EmollientGlycerin
HumectantPolysorbate 20
EmulsifyingPolysilicone-11
Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone
Skin ConditioningHyaluronic Acid
HumectantResveratrol
AntioxidantNiacinamide
SmoothingQuercetin
AntioxidantAdenosine
Skin ConditioningTetrahexyldecyl Ascorbate
AntioxidantTocopherol
AntioxidantPhospholipids
Skin ConditioningUbiquinone
AntioxidantEpigallocatechin Gallate
AntioxidantSea Whip Extract
Skin ConditioningBisabolol
AntioxidantBeta-Glucan
Skin ConditioningPhytic Acid
Xanthan Gum
EmulsifyingAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingSodium Hydroxide
BufferingDisodium EDTA
Ethylhexylglycerin
Skin ConditioningPhenoxyethanol
PreservativeWater, Cyclopentasiloxane, Butylene Glycol, Dimethicone, Glycerin, Polysorbate 20, Polysilicone-11, Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone, Hyaluronic Acid, Resveratrol, Niacinamide, Quercetin, Adenosine, Tetrahexyldecyl Ascorbate, Tocopherol, Phospholipids, Ubiquinone, Epigallocatechin Gallate, Sea Whip Extract, Bisabolol, Beta-Glucan, Phytic Acid, Xanthan Gum, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Sodium Hydroxide, Disodium EDTA, Ethylhexylglycerin, Phenoxyethanol
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.
The way it works is fairly well mapped out:
Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.
The clinical backing is pretty solid too.
A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.
A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.
On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.
This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.
Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.
Learn more about AdenosineBisabolol is a gentle skin conditioner, antioxidant, and soothing ingredient.
It's primary claim to fame is soothing and research shows topically applied bisabolol can quiet the chemical messengers that cause your skin to become inflamed, helping to sooth any irritation.
A clinical study found that applying 0.5% bisabolol daily for 8 weeks produced an average 9% decrease in skin pigmentation. Researchers found it can also suppress the process that leads to excess melanin production in skin.
In vitro studies found that bisabolol combined with propylene glycol significantly increased skin permeability by increasing lipid fluidity in the stratum corneum.
You'll likely see use concentrations quite low, usually 0.1-0.2%.
Overall, this is a well-tolerated ingredient that works well in formulas designed for sensitive, reactive, or post-procedure skin.
Learn more about BisabololCyclopentasiloxane (D5) is a lightweight silicone that mostly acts as an emollient and solvent in cosmetics. Its the reason your products feel silky, fast-spreading, and non-greasy.
Since D5 is volatile, it does its thing and then evaporates off the skin quickly.
The safety profile of this ingredient is reassuring; the US CIR Expert Panel concluded D5 is safe as used in cosmetics and Health Canada concluded that D5 is not harmful to human health or the environment as currently used in cosmetics
There's a study that people mention about D5 in a rat study showing tumors. This study is related to long-term inhalation of high D5 levels.
Regulatory bodies have judged this study to be not applicable in topical skincare since skin absorption of D5 is very low and we're not really inhaling huge amounts of D5.
The only restriction for this ingredient is environmental. The European Chemicals Agency (ECHA) restricted D5 in wash-off cosmetics at or above 0.1% due to their persistence in water.
Learn more about CyclopentasiloxaneDimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Learn more about DimethiconeTetrahexyldecyl Ascorbate (THD) is a stable and oil-soluble form of Vitamin C.
THD is special in that it has the ability to travel deeper into skin than traditional ascorbic acid while maintaining the same skin benefits (double win!).
Because it’s oil-soluble, THD dives deep into your skin’s fatty layers (think ceramides and cholesterol) to fight off the kind of free radicals that mess with your skin barrier. This makes it a great pair with water-based vitamin C (ascorbic acid) that mainly works on the surface.
Even at just 0.1%, THD is already showing great antioxidant activity. When used up to 2%, it helps keep your skin happy and calm, especially when it’s stressed from pollution or sun.
Want to fade dark spots or tackle hyperpigmentation? You’ll want 5% or more. Pairing it with brightening buddies like niacinamide or licorice root gives even better results. One study even used 30% THD with other brighteners and saw real results on stubborn discoloration, even in melasma-prone skin.
A note on THD: It’s has a slightly silky, oily texture and usually shows up colorless or pale yellow (though the exact shade can vary by supplier).
While you can sneak it into water-based formulas, it really shines when paired with silicones or oils, which help your skin soak it up better.
THD is pretty stable, but it’s still vulnerable to degradation like ascorbic acid. Too much light or heat (above 113°F / 45°C) can break it down over time. Go for dark and opaque packaging that keeps it safe and shady!
Read more about other types of Vitamin C:
Learn more about Tetrahexyldecyl AscorbateTocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.
Learn more about Tocopherol