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Paula's Choice Peptide Booster Versus Le Mieux TGF-B Booster

Facial Treatment
Serum
American Brand United States
American Brand United States

Updated on July 18, 2024

Overview

What they are

These products are both cruelty-free and reef safe . They have a total of 10 ingredients in common

Cool Features

They both contain peptides

Suited For

They're both likely to be good for anti aging, dry skin, brightening skin, sensitive skin, scar healing and dark spots

Free From

They both do not contain any harsh alcohols, common allergens, oils, parabens or sulfates

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

Paula's Choice Peptide Booster 56 ingredients

Le Mieux TGF-B Booster 32 ingredients

ph level
4

At a glance

Click on any of the items below to learn more

Paula's Choice Peptide Booster 56 ingredients

Le Mieux TGF-B Booster 32 ingredients

Notable Ingredients

Benefits

Concerns

Notable Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Peptide Booster
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Peg-8 Dimethicone Emulsifying
Silicon Icon
SiliconSilicon Icon

Peg-8 Dimethicone is a type of silicone.

Unknown Full details ->
Tripeptide-1 Skin Conditioning, Skin Protecting
Peptide Icon
PeptidePeptide Icon

Tripeptide-1 is a peptide.

Palmitoyl Tripeptide-1 Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon
PeptidePeptide Icon Not safe for Fungal AcneNot safe for Fungal Acne Icon

Palmitoyl Tripeptide-1 is a 3-amino acid peptide. Peptides are building blocks for protein.

Palmitoyl Tetrapeptide-7 Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon
PeptidePeptide Icon Not safe for Fungal AcneNot safe for Fungal Acne Icon

Palmitoyl Tetrapeptide-7 is a peptide. Peptides are building blocks for protein.

Palmitoyl Hexapeptide-12 Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon
PeptidePeptide Icon Not safe for Fungal AcneNot safe for Fungal Acne Icon

Palmitoyl Hexapeptide-12 isn't fungal acne safe and is a peptide.

Myristoyl Hexapeptide-16 Skin Conditioning
Peptide Icon
PeptidePeptide Icon

Myristoyl Hexapeptide-16 is a peptide.

Myristoyl Pentapeptide-17 Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon
PeptidePeptide Icon Not safe for Fungal AcneNot safe for Fungal Acne Icon

Myristoyl Pentapeptide-17 isn't fungal acne safe and is a peptide.

Hexanoyl Dipeptide-3 Norleucine Acetate Skin Conditioning
Peptide Icon
PeptidePeptide Icon

Hexanoyl Dipeptide-3 Norleucine Acetate is a peptide.

Azelaoyl Bis-Dipeptide-10 Skin Conditioning
Peptide Icon
PeptidePeptide Icon

Azelaoyl Bis-Dipeptide-10 is a synthetically created peptide from azelaid acid.

Unknown Full details ->
Glycoproteins Skin Conditioning
Helps hydrate Dry Skin Icon
Helps hydrate Dry SkinHelps hydrate Dry Skin Icon

Glycoproteins can be good for be good for dry skin.

Phospholipids Skin Conditioning

Phospholipids are naturally found in our skin as they are the main component of cell membranes. Phospholipids have humectant, emollient, antioxidant properties.

Adenosine Skin Conditioning
Helps with Anti-Aging IconGood for Scar Healing Icon
2 Benefits

Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.

Dipotassium Glycyrrhizate Humectant, Skin Conditioning
Helps reduce Skin Redness IconHelps reduce irritation IconGood for Dark Spots Icon
3 Benefits

Dipotassium Glycyrrhizate comes from licorice root.

Arginine Masking, Skin Conditioning
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Arginine is an amino acid that is important for human development. Your body uses is it to produce hair keratin and skin collagen.

Valine Masking, Skin Conditioning

We don't have a description for Valine.

Glycine Buffering, Skin Conditioning

Glycine is an amino acid that helps build proteins. It is already present in our skin as our bodies produce them naturally.

Alanine Masking, Skin Conditioning

Alanine is an amino acid and is already found in the human body.

Glutamic Acid Humectant

Glutamic Acid is an amino acid that is found in all living organisms. Our bodies use this to help nerve cells in the brain communicate with other cells.

Serine Masking, Skin Conditioning

Serine is an amino acid naturally found in our body. Our bodies use amino acids to create protein.

Threonine

Threonine is an amino-acid. It helps hydrate the skin and has antioxidant benefits.

Yeast Extract Skin Conditioning, Skin Protecting

We don't have a description for Yeast Extract.

Isoleucine Skin Conditioning

We don't have a description for Isoleucine.

Proline Skin Conditioning

Proline is an amino-acid. It helps moisturize the skin and plays an important role in creating proteins.

Histidine Humectant, Skin Conditioning

We don't have a description for Histidine.

Phenylalanine Masking, Skin Conditioning

Phenylalanine is an amino acid. It is a skin soothing and hydrating ingredient. Amino acids play a crucial role in wound healing and skin hydration.

PCA Humectant, Moisturising

PCA is derived from amino acids and is naturally found in our skin's barrier.

Phytic Acid
AHA IconHelps brighten skin IconMay worsen Rosacea Icon
AHAAHA Icon Helps brighten skinHelps brighten skin Icon May worsen RosaceaMay worsen Rosacea Icon

Phytic Acid is a gentle AHA and antioxidant. The chemical makeup makes it classified as an AHA, such as lactic acid.

Panax Ginseng Root Extract Emollient, Skin Protecting, Tonic
Helps hydrate Dry Skin IconHelps reduce Skin Redness Icon
2 Benefits

Panax Ginseng Root is a popular herb from Asia. This root contains antioxidants, favonoids, and vitamins B12 and D.

Sodium PCA Humectant, Skin Conditioning
0 / 0

Sodium PCA is the sodium salt of pyroglutamic acid and is naturally occurring on human skin.

0 Com. / 0 Irr.
Psidium Guajava Fruit Extract Astringent, Skin Conditioning

We don't have a description for Psidium Guajava Fruit Extract.

Euterpe Oleracea Fruit Extract

This extract comes from the Cabbage Palm, AKA the Açaí berry! It has skin soothing, antioxidant, and anti-aging properties.

Ahnfeltiopsis Concinna Extract Skin Conditioning

Ahnfeltiopsis Concinna Extract is derived from red algae. It helps soothe skin and provides antioxidants.

Disliked Full details ->
Dextran

We don't have a description for Dextran.

Unknown Full details ->
Hydrolyzed Silk Humectant, Skin Conditioning

You can find hydrolyzed silk in both haircare and skincare products. According to a manufacturer, it can help improve skin and hair hydration.

Lecithin Emollient, Emulsifying, Skin Conditioning

Lecithin is a term for a group of substances found in plants, animals, and humans. They are made up of mixture of fatty acids. These fatty acids usually are a mixture of phosphoric acid's choline ester connected to stearic, oleic, and palmitic acids. Most lecithins are created from plant ingredients scuh as sunflower.

Disliked Full details ->
Glyceryl Polymethacrylate

We don't have a description for Glyceryl Polymethacrylate.

C12-16 Pareth-9 Emulsifying

We don't have a description for C12-16 Pareth-9.

Unknown Full details ->
Trideceth-12 Emulsifying

We don't have a description for Trideceth-12.

Unknown Full details ->
Sodium Lactate Buffering, Humectant

Sodium Lactate is the sodium salt of lactic acid, an AHA. It is a humectant and used to adjust the pH of a product.

Carbomer Emulsion Stabilising, Gel Forming
1 / 0

Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.

1 Com. / 0 Irr.
Disliked Full details ->
Aspartic Acid Masking, Skin Conditioning

Aspartic Acid is an amino acid that our bodies produce naturally. It is an antioxidant.

Polysorbate 20 Emulsifying
0 / 0 Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.

0 Com. / 0 Irr.
Very Disliked Full details ->
Butylene Glycol Humectant, Masking, Skin Conditioning
1 / 0

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

1 Com. / 0 Irr.
Caprylyl Glycol Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

Peg-8 Humectant, Solvent

PEG-8 is a synthetic polymer used as a humectant and solvent.

Very Disliked Full details ->
C11-15 Pareth-7 Emulsifying

We don't have a description for C11-15 Pareth-7.

Unknown Full details ->
Guar Hydroxypropyltrimonium Chloride Skin Conditioning

This ingredient is derived from guar gum.

Phytosteryl/Octyldodecyl Lauroyl Glutamate Skin Conditioning

We don't have a description for Phytosteryl/Octyldodecyl Lauroyl Glutamate.

Unknown Full details ->
Ectoin Skin Conditioning

Ectoin is a compound found naturally in some species of bacteria. It can be synthetically created for skincare use.

Citrate Buffer

We don't have a description for Citrate Buffer.

Unknown Full details ->
Trimethylsiloxyamodimethicone
Silicon IconHelps hydrate Dry Skin Icon
SiliconSilicon Icon Helps hydrate Dry SkinHelps hydrate Dry Skin Icon

Trimethylsiloxyamodimethicone (don't worry, we cannot pronounce this either) is a siloxane polymer. Siloxane polymers are widely used as antimicrobials and texture enhancer. This ingredient is synthetically created.

Phenoxyethanol Preservative
Preservative Icon
PreservativePreservative Icon

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

Very Disliked Full details ->
Sodium Hydroxide Buffering

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

Ethylhexylglycerin Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

TGF-B Booster
Hyaluronic Acid Humectant, Moisturising, Skin Conditioning
Hyaluronic Acid IconGood for Skin Texture IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin IconMay cause irritation Icon
Hyaluronic AcidHyaluronic Acid Icon 4 Benefits May cause irritationMay cause irritation Icon

Hyaluronic acid is naturally found in healthy skin. It is a humectant, meaning it draws moisture to your skin.

Hydrolyzed Sodium Hyaluronate Skin Conditioning

This ingredient is created by putting sodium hyaluronate through hydrolysis.

Sodium Hyaluronate Humectant, Skin Conditioning
0 / 0 Hyaluronic Acid Icon
Hyaluronic AcidHyaluronic Acid Icon

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

0 Com. / 0 Irr.
Sodium Hyaluronate Crosspolymer Humectant, Skin Conditioning
Hyaluronic Acid Icon
Hyaluronic AcidHyaluronic Acid Icon

Sodium Hyaluronate Crosspolymer is a type of hyaluronic acid. In fact, it is modified version of hyaluronic acid.

Hydroxypropyltrimonium Hyaluronate

This form of hyaluronic acid is produced through fermentation.

C12-13 Alkyl Glyceryl Hydrolyzed Hyaluronate

We don't have a description for C12-13 Alkyl Glyceryl Hydrolyzed Hyaluronate.

Disliked Full details ->
Superoxide Dismutase Antioxidant, Skin Conditioning
Antioxidant Icon
AntioxidantAntioxidant Icon

Superoxide Dismutase is found in all living cells. This ingredient is AKA as 'SOD'.

Saccharomyces Polypeptides Skin Conditioning
Peptide Icon
PeptidePeptide Icon

Peptides are amino acids naturally found in your skin. These amino acids make up many proteins your skin uses. Collagen is made up of peptides. Collagen is responsible for keeping your skin plump and youthful.

Palmitoyl Tetrapeptide-7 Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon
PeptidePeptide Icon Not safe for Fungal AcneNot safe for Fungal Acne Icon

Palmitoyl Tetrapeptide-7 is a peptide. Peptides are building blocks for protein.

Palmitoyl Tripeptide-5 Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon
PeptidePeptide Icon Not safe for Fungal AcneNot safe for Fungal Acne Icon

Palmitoyl Tripeptide-5 isn't fungal acne safe and is a peptide.

Palmitoyl Tripeptide-1 Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon
PeptidePeptide Icon Not safe for Fungal AcneNot safe for Fungal Acne Icon

Palmitoyl Tripeptide-1 is a 3-amino acid peptide. Peptides are building blocks for protein.

Acetyl Octapeptide-3 Humectant, Skin Conditioning
Peptide Icon
PeptidePeptide Icon

Acetyl Octapeptide-3 is a synthetic peptide. It is often called a botox alternative due to its ability to restrict the movement of muscles, and thus reduce the appearance of fine-lines.

Ceramide Ns Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconHelps with Anti-Aging Icon
CeramideCeramide Icon 4 Benefits

Ceramide NS is a type of Ceramide. Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. They are known for their ability to hold water and thus are a great ingredient for dry skin.

Saccharomyces/Copper Ferment Skin Conditioning

We don't have a description for Saccharomyces/Copper Ferment.

Saccharomyces/Zinc Ferment Skin Conditioning

We don't have a description for Saccharomyces/Zinc Ferment.

Saccharomyces/Manganese Ferment Skin Conditioning

We don't have a description for Saccharomyces/Manganese Ferment.

Unknown Full details ->
Riboflavin Cosmetic Colorant, Skin Conditioning

Riboflavin is Vitamin B2. Our bodies use riboflavin in the creation of skin, digestive tract lining, and blood cells.

Phospholipids Skin Conditioning

Phospholipids are naturally found in our skin as they are the main component of cell membranes. Phospholipids have humectant, emollient, antioxidant properties.

Folic Acid Skin Conditioning

Folic acid is a form of Vitamin B9. Our bodies use folic acid for creating new cells and for DNA repair.

Enteromorpha Compressa Extract Skin Protecting

We don't have a description for Enteromorpha Compressa Extract.

Glycoproteins Skin Conditioning
Helps hydrate Dry Skin Icon
Helps hydrate Dry SkinHelps hydrate Dry Skin Icon

Glycoproteins can be good for be good for dry skin.

Ginkgo Biloba Leaf Extract Skin Conditioning

Ginkgo Biloba Leaf Extract comes from the leaves of the Ginkgo tree. This tree is native to China and has been used in traditional Chinese medicine for thousands of years.

Serine Masking, Skin Conditioning

Serine is an amino acid naturally found in our body. Our bodies use amino acids to create protein.

Proline Skin Conditioning

Proline is an amino-acid. It helps moisturize the skin and plays an important role in creating proteins.

Alanine Masking, Skin Conditioning

Alanine is an amino acid and is already found in the human body.

Glutamic Acid Humectant

Glutamic Acid is an amino acid that is found in all living organisms. Our bodies use this to help nerve cells in the brain communicate with other cells.

Niacinamide Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconGood for Minimizing Pores IconGood for Dark Spots IconHelps fight Acne IconHelps brighten skin Icon
NiacinamideNiacinamide Icon 6 Benefits

Niacinamide has emerged as an all-star ingredient due to its many benefits.

Parfum Masking, Perfuming
Fragrance IconMay worsen Eczema IconMay worsen Rosacea Icon
FragranceFragrance Icon 2 Concerns

Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.

Very Disliked Full details ->
Caprylyl Glycol Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

Ethylhexylglycerin Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

Undecylenoyl Glycine Cleansing

We don't have a description for Undecylenoyl Glycine.

Unknown Full details ->
Capryloyl Glycine Cleansing

Capryloyl Glycine is created by adding an acyl group to glycine and caprylic acid chloride.

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning
Liked

Palmitoyl Tripeptide-1 is a 3-amino acid peptide. Peptides are building blocks for protein.

Palmitoyl Tripeptide-1 is a signal peptide. This means it tells our skin to create collagen. Collagen is a protein that makes connective tissue. Boosting collagen production leads to a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin.

Palmitoyl Tripeptide-1 can help reduce wrinkles and make the skin look more youthful.

Read more about other common types of peptides here:

Learn more about Palmitoyl Tripeptide-1
Skin Conditioning
Liked

Palmitoyl Tetrapeptide-7 is a peptide. Peptides are building blocks for protein.

This ingredient consists of four amino acids and palmitic acid. These amino acids are arginine, proline, glutamine, and glycine.

This ingredient has many benefits. These benefits include boosting collagen production, fighting inflammation, and reversing UV damage.

By preventing our bodies from producing interleukins, Palmitoyl Tetrapeptide-7 helps fight inflammation. An interleukin is a chemical that signals to the body to produce an inflammatory response. Interleukin production is accelerated by UV radiation.

Palmitoyl Tetrapeptide-7 tells our body to create more collagen. Collagen is a protein that makes connective tissue. Boosting collagen production leads to a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin.

Read more about other common types of peptides here:

Learn more about Palmitoyl Tetrapeptide-7
Skin Conditioning
Loved

Glycoproteins can be good for be good for dry skin.

Skin Conditioning
Loved

Phospholipids are naturally found in our skin as they are the main component of cell membranes. Phospholipids have humectant, emollient, antioxidant properties.

The phospholipids in our skin can be naturally depleted. Replenishing the phospholipids in our skin can help hydrate your skin. Due to their hygroscopic nature, they act as humectants and emollients. Humectants draw moisture from the air to your skin, while emollients help trap moisture in. This ingredient is non-occlusive.

Studies show phospholipids display antioxidant activity and may help with reducing the signs of aging.

Phospholipids are complex lipids that contain glycerin, two fatty acids, and a phosphate group. Some foods that contain phospholipids include soybeans and milk. The phospholipids found in soy come from Lecithin. This ingredient can also be synthetically created.

Some types of phospholipids:

Learn more about Phospholipids
Masking, Skin Conditioning
Loved

Alanine is an amino acid and is already found in the human body.

Alanine has antioxidant properties and can help with anti-aging.

Alanine is used by fibrous proteins such as collagen, elastin, and keratin. These three help make a strong skin barrier. Having a healthy skin barrier leads to more plump and youthful skin.

Learn more about Alanine
Humectant
Loved

Glutamic Acid is an amino acid that is found in all living organisms. Our bodies use this to help nerve cells in the brain communicate with other cells.

In cosmetics, glutamic acid is a famous humectant. It draws water from the air to your skin, keeping your skin hydrated (like hyaluronic acid).

An in-vitro study from 2024 found glutamic acid to play a role in inhibiting inflammation and thus a potential skin-soothing ingredient.

Other studies show it to be have potential wound healing, skin barrier repair, and hair growth properties.

Glutamic acid has poor solubility in water and other solvents.

Learn more about Glutamic Acid
Masking, Skin Conditioning
Loved

Serine is an amino acid naturally found in our body. Our bodies use amino acids to create protein.

Amino-acids help give keep our skin hydrated. They play an important role in the skin barrier, which keeps the skin plump and firm.

Serine is a non-essential amino acid, meaning we don't need to obtain it from eating foods.

Learn more about Serine
Skin Conditioning
Loved

Proline is an amino-acid. It helps moisturize the skin and plays an important role in creating proteins.

Proline is one of the building blocks for producing collagen. As we age, our bodies produce less collagen. Collagen helps the skin look plump and firm.

In medicine, proline is used as an osmoprotectant. This means it helps prevent oxidative degradation in other drugs.

Our bodies are able to produce proline naturally, but certain conditions may inhibit this production. In that case, proline can be obtained from eating egg whites, soy protein, dairy products, asparagus, mushrooms, and seaweed.

Learn more about Proline
Emollient, Humectant, Skin Conditioning
Liked

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.

Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.

This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.

Learn more about Caprylyl Glycol
Skin Conditioning
Mixed

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.

Ingredient Ratings

Here's what our community thinks of the ingredients in these products.

Peptide Booster
36
6
6
8
liked
mixed
disliked
not rated
TGF-B Booster
22
6
2
2
liked
mixed
disliked
not rated

When to use

Paula's Choice Peptide Booster 56 ingredients

Le Mieux TGF-B Booster 32 ingredients

55 Routines
45% use in am
55% use in pm
95% use every day
When to use See routines that use it ->
16 Routines
56% use in am
44% use in pm
94% use every day

Reviews

Here's what our community thinks

Paula's Choice Peptide Booster 56 ingredients

Peptide Booster hasn't been rated yet.
Rate it now

Le Mieux TGF-B Booster 32 ingredients

5.0 /5
from 1 rating
Absorbs Well (1) Hydrating (1) No Scent (1)
Lady_McGregor's avatar

Lady_McGregor

12 months ago · Normal Skin
Review

On my wish list. According to my research, it seems to have quality growth factor ingredients, hydrating ingredients, and few of any ingredients...

On my wish list. According to my research, it seems to have quality growth factor ingredients, hydrating ingredients, and few of any ingredients I’m looking to avoid.

Edit: Finally splurged, and it is worth every penny. I can’t believe how great my skin looks and feels after just a few days. I’m trying using it every other day to make it more affordable. Will let you know how that goes.

Highly recommend!