Paula's Choice RESIST Daily Smoothing Treatment With 5% AHA Versus Philosophy Clear Days Ahead Fast-Acting Salicylic Acid Acne Spot Treatment
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningGlycolic Acid
BufferingCetyl Alcohol
EmollientButylene Glycol
HumectantPolyacrylamide
Dimethicone
EmollientPPG-14 Butyl Ether
Skin ConditioningPalmitoyl Hexapeptide-12
Skin ConditioningCeramide Ng
Skin ConditioningTetrahydrodiferuloylmethane
AntioxidantTetrahydrodemethoxydiferuloylmethane
AntioxidantTetrahydrobisdemethoxydiferuloylmethane
AntioxidantEpigallocatechin Gallate
AntioxidantSalicylic Acid
MaskingDisodium Lauriminodipropionate Tocopheryl Phosphates
CleansingPEG-10 Phytosterol
EmulsifyingVanilla Planifolia Fruit Extract
Skin ConditioningBisabolol
AntioxidantAllantoin
Skin ConditioningCyclopentasiloxane
EmollientCyclohexasiloxane
EmollientDimethiconol
EmollientTribehenin
EmollientC12-15 Alkyl Benzoate
AntimicrobialPEG-40 Stearate
EmulsifyingSorbitan Stearate
EmulsifyingPvm/Ma Decadiene Crosspolymer
Disodium EDTA
C13-14 Isoparaffin
EmollientLaureth-7
EmulsifyingSodium Hydroxide
BufferingCaprylyl Glycol
EmollientCaprylic/Capric Triglyceride
MaskingHexylene Glycol
EmulsifyingEthylhexylglycerin
Skin ConditioningPhenoxyethanol
PreservativeWater, Glycolic Acid, Cetyl Alcohol, Butylene Glycol, Polyacrylamide, Dimethicone, PPG-14 Butyl Ether, Palmitoyl Hexapeptide-12, Ceramide Ng, Tetrahydrodiferuloylmethane, Tetrahydrodemethoxydiferuloylmethane, Tetrahydrobisdemethoxydiferuloylmethane, Epigallocatechin Gallate, Salicylic Acid, Disodium Lauriminodipropionate Tocopheryl Phosphates, PEG-10 Phytosterol, Vanilla Planifolia Fruit Extract, Bisabolol, Allantoin, Cyclopentasiloxane, Cyclohexasiloxane, Dimethiconol, Tribehenin, C12-15 Alkyl Benzoate, PEG-40 Stearate, Sorbitan Stearate, Pvm/Ma Decadiene Crosspolymer, Disodium EDTA, C13-14 Isoparaffin, Laureth-7, Sodium Hydroxide, Caprylyl Glycol, Caprylic/Capric Triglyceride, Hexylene Glycol, Ethylhexylglycerin, Phenoxyethanol
Salicylic Acid 2%
MaskingWater
Skin ConditioningDimethicone
EmollientIsododecane
EmollientAlcohol Denat.
AntimicrobialPolysilicone-11
Glycereth-7 Trimethyl Ether
Skin ConditioningPropanediol
SolventGlycolic Acid
BufferingPolyacrylamide
Isopropyl Myristate
EmollientCoco-Caprylate/Caprate
EmollientEthoxydiglycol
HumectantC13-14 Isoparaffin
EmollientSodium Acrylates Copolymer
Trimethylpentanediol/Adipic Acid Copolymer
Skin ConditioningSodium Hydroxide
BufferingButylene Glycol
HumectantLaureth-7
EmulsifyingBisabolol
AntioxidantDecyl Glucoside
CleansingLecithin
EmollientLauryl Glucoside
CleansingDisodium EDTA
Laureth-12
EmulsifyingPhenoxyethanol
PreservativeCaprylyl Glycol
EmollientHexylene Glycol
EmulsifyingEthylhexylglycerin
Skin ConditioningFarnesol
PerfumingSalicylic Acid 2%, Water, Dimethicone, Isododecane, Alcohol Denat., Polysilicone-11, Glycereth-7 Trimethyl Ether, Propanediol, Glycolic Acid, Polyacrylamide, Isopropyl Myristate, Coco-Caprylate/Caprate, Ethoxydiglycol, C13-14 Isoparaffin, Sodium Acrylates Copolymer, Trimethylpentanediol/Adipic Acid Copolymer, Sodium Hydroxide, Butylene Glycol, Laureth-7, Bisabolol, Decyl Glucoside, Lecithin, Lauryl Glucoside, Disodium EDTA, Laureth-12, Phenoxyethanol, Caprylyl Glycol, Hexylene Glycol, Ethylhexylglycerin, Farnesol
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Bisabolol is a gentle skin conditioner, antioxidant, and soothing ingredient.
It's primary claim to fame is soothing and research shows topically applied bisabolol can quiet the chemical messengers that cause your skin to become inflamed, helping to sooth any irritation.
A clinical study found that applying 0.5% bisabolol daily for 8 weeks produced an average 9% decrease in skin pigmentation. Researchers found it can also suppress the process that leads to excess melanin production in skin.
In vitro studies found that bisabolol combined with propylene glycol significantly increased skin permeability by increasing lipid fluidity in the stratum corneum.
You'll likely see use concentrations quite low, usually 0.1-0.2%.
Overall, this is a well-tolerated ingredient that works well in formulas designed for sensitive, reactive, or post-procedure skin.
Learn more about BisabololButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolThis ingredient is also known as "C13-14 Isoalkane".
C13-14 Isoparaffin is created from petroleum-based mineral oils. It is an emollient and helps thicken a product.
As an emollient, it helps keep the skin soft and smooth by creating a barrier on top. This barrier traps moisture in, keeping the skin hydrated.
C13-14 Isoparaffin may not be fungal-acne safe.
Learn more about C13-14 IsoparaffinCaprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid or alcohol, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Learn more about Caprylyl GlycolDimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Learn more about DimethiconeDisodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Learn more about Disodium EDTAEthylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinGlycolic Acid is arguably the most famous alpha hydroxy acid (AHA) with tons of research backing its benefits.
It is found naturally in sugar cane but the form used in skincare is usually synthetic for purity and stability.
Glycolic acid removes the top layer of dead skin cells to allow newer and fresher ones to emerge.
AHAs work by breaking down the structural “glue” that holds old skin cells in place. When that buildup is gone, your skin can renew itself more efficiently.
Research also shows glycolic acid stimulates collagen production, helping to firm and thicken the skin over time. This is one of its biggest advantages over other AHAs.
Overall, glycolic acid helps with:
Fun fact: Glycolic acid boosts skin hydration by helping it produce molecules that increase hyaluronic acid naturally.
To work best, glycolic acid products should have a pH between 3-4 (that’s where exfoliation is most effective but still gentle on skin).
The pH and concentration of a product are key to its effectiveness:
It is normal to feel a slight stinging sensation when using glycolic acid. This usually fades as your skin adjusts.
Because glycolic acid has the smallest molecular size in the AHA family, it can penetrate deeper, which enhances its effectiveness but also makes it more likely to irritate sensitive skin.
If your skin is very sensitive or prone to rosacea, glycolic acid may be too strong; in that case, try milder options like lactic acid or a PHA instead.
Recent studies suggest glycolic acid might even help protect against UV damage. But don’t skip sunscreen! Freshly exfoliated skin is more sensitive to the sun.
Glycolic acid is a skincare superstar. It smooths, brightens, hydrates, and firms the skin. Unless you’re highly sensitive, it’s well worth adding to your routine.
Read more about some other popular AHA's here:
Learn more about Glycolic AcidHexylene Glycol is a multitasker ingredient that works as a solvent, humectant, emulsifier, viscosity reducer, and preservative booster.
It is able to dissolve both water and oil-soluble ingredients to stabilize tricky actives and make products spread more easily.
As a humectant, it pulls water into the skin. But it's a pretty minor moisturizing ingredient compared to other humectants, like glycerin.
Interestingly, it can act as a mild penetration enhancer. One in vitro study on human skin found a 12% concentration upped the absorption of mometasone furoate (a medicinal ingredient used to treat inflammatory skin conditions) up to 7%.
This ingredient is typically used at levels of 0.1-10% depending on the role it's playing.
A patch test study on eczema patients didn't find a significant increase in irritation versus the control group, but the potential for irritation rises at higher concentrations.
Learn more about Hexylene GlycolLaureth-7 is created by the ethoxylation of lauryl alcohol using ethylene oxide. Lauryl alcohol is a fatty alcohol with hydrating properties.
This ingredient is an emulsifier and cleansing ingredient. As an emulsifier, it is used to prevent ingredients from separating. It also helps cleanse the skin by gathering dirt, oil, and pollutants to be rinsed away.
Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Polyacrylamide is a synthetic polymer. It is used to stabilize products and bind ingredients. When hydrated, Polyacrylamide forms a soft gel.
Polyacrylamide is low-toxicity. If source properly, it is deemed safe to use in cosmetics.
It should be noted the precursor to Polyacrylamide is acrylamide. Acrylamide is a carcinogen. Most reputable sources of Polyacrylamide will screen for residual acrylamide to make sure the count is in a safe range. Acrylamide is not able to be absorbed through the skin.
We recommend speaking with a professional if you have concerns.
Learn more about PolyacrylamideSalicylic Acid (also known as beta hydroxy acid or BHA) is a well-known ingredient for treating skin that struggles with acne and clogged pores. It exfoliates both the skin's surface and deep within the pores to help clear out buildup, control oil, and reduce inflammation.
Unlike AHAs (alpha hydroxy acids), salicylic acid is oil-soluble. This allows it to penetrate into pores which makes it especially effective for treating blackheads and preventing future breakouts.
Salicylic acid is also known for its soothing properties. It has a similar structure to aspirin and can calm inflamed or irritated skin, making it a good option for acne-prone skin that is also sensitive.
Concentrations of 0.5-2% are recognized by the U.S. FDA as an over-the-counter topical acne product.
It can cause irritation and/or dryness if one's skin already has a compromised moisture barrier, so it's best to focus on repairing that before introducing this ingredient into your routine.
While salicylic acid does not increase sun sensitivity, it’s still important to wear sunscreen daily to protect your skin.
If you are looking for the ingredient called BHA or Butylated Hydroxyanisole, click here.
Learn more about Salicylic AcidSodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Learn more about Sodium HydroxideWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water