What's inside

What's inside

Key Ingredients

Benefits

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Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Antioxidant, Masking, Skin Conditioning

Bisabolol is a gentle skin conditioner, antioxidant, and soothing ingredient.

It's primary claim to fame is soothing and research shows topically applied bisabolol can quiet the chemical messengers that cause your skin to become inflamed, helping to sooth any irritation.

A clinical study found that applying 0.5% bisabolol daily for 8 weeks produced an average 9% decrease in skin pigmentation. Researchers found it can also suppress the process that leads to excess melanin production in skin.

In vitro studies found that bisabolol combined with propylene glycol significantly increased skin permeability by increasing lipid fluidity in the stratum corneum.

You'll likely see use concentrations quite low, usually 0.1-0.2%.

Overall, this is a well-tolerated ingredient that works well in formulas designed for sensitive, reactive, or post-procedure skin.

Learn more about Bisabolol

Dimethyl Isosorbide is a low-irritation solvent that helps deliver actives into your skin. It is created from glucose.

Research shows how well this ingredient works depends on the active and formulation rather than the concentration alone. This means adding more Dimethyl Isosorbide does not guarantee better penetration of ingredients into the skin.

Skin Conditioning

This ingredient is a retinoid. It usually goes by a more common name: "Granactive".

Hydroxypinacolone Retinoate (HPR) belongs to the class of retinoids that also includes retinol and tretinoin.

Retinoids have been proven to:

So what is the difference between all the retinoids?
Most retinoids need to go through a conversion line to become effective on skin. The ending product is retinoic acid. Retinoic acid is AKA tretinoin.

HPR is an ester of tretinoin. Emerging studies suggest HPR to have an added benefit that other retinoids don't have: Low irritation.

A study from 2021 found HPR to have the greatest stability when exposed to light and temperature out of all the commercial retinoids.

A note about naming:
The name "Granactive" is the trade name and the name most commonly used on packages.

Granactive is the name of the mixture - about 90% solvent and 10% HPR. A product with 5% granactive has 0.5% HPR.

Learn more about Hydroxypinacolone Retinoate

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