What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningButylene Glycol
HumectantPalmitoyl Tripeptide-5
Skin ConditioningAcetyl Hexapeptide-8
HumectantGlycine
BufferingSerine
MaskingGlutamic Acid
HumectantAspartic Acid
MaskingLeucine
Skin ConditioningAlanine
MaskingLysine
Skin ConditioningArginine
MaskingTyrosine
MaskingPhenylalanine
MaskingThreonine
Proline
Skin ConditioningValine
MaskingIsoleucine
Skin ConditioningHistidine
HumectantMethionine
Skin ConditioningCysteine
AntioxidantHouttuynia Cordata Extract
Skin ConditioningCamellia Sinensis Leaf Extract
AntimicrobialBetaine
HumectantSodium Hyaluronate
HumectantPanthenol
Skin ConditioningBeta-Glucan
Skin ConditioningGlycerin
Humectant1,2-Hexanediol
Skin ConditioningAllantoin
Skin ConditioningAmmonium Acryloyldimethyltaurate/Vp Copolymer
Sodium Phytate
Sodium Citrate
BufferingCitric Acid
BufferingHydroxyacetophenone
AntioxidantPentylene Glycol
Skin ConditioningCaprylyl Glycol
EmollientWater, Butylene Glycol, Palmitoyl Tripeptide-5, Acetyl Hexapeptide-8, Glycine, Serine, Glutamic Acid, Aspartic Acid, Leucine, Alanine, Lysine, Arginine, Tyrosine, Phenylalanine, Threonine, Proline, Valine, Isoleucine, Histidine, Methionine, Cysteine, Houttuynia Cordata Extract, Camellia Sinensis Leaf Extract, Betaine, Sodium Hyaluronate, Panthenol, Beta-Glucan, Glycerin, 1,2-Hexanediol, Allantoin, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Sodium Phytate, Sodium Citrate, Citric Acid, Hydroxyacetophenone, Pentylene Glycol, Caprylyl Glycol
Water
Skin ConditioningButylene Glycol
HumectantGlycerin
Humectant1,2-Hexanediol
Skin ConditioningPropanediol
SolventPentylene Glycol
Skin ConditioningSodium Polyacryloyldimethyl Taurate
Emulsion StabilisingAmmonium Polyacryloyldimethyl Taurate
Emulsion StabilisingPanthenol
Skin ConditioningBiotin
AntiseborrhoeicTromethamine
BufferingAcetyl Glucosamine
Skin ConditioningSodium Phytate
Sodium Hyaluronate
HumectantCitric Acid
BufferingHydroxyacetophenone
AntioxidantCynanchum Atratum Extract
Skin ConditioningSodium Hyaluronate Crosspolymer
HumectantDipropylene Glycol
HumectantBiotinoyl Tripeptide-1
Caprylyl Glycol
EmollientBetaine
HumectantMadecassoside
AntioxidantCentella Asiatica Leaf Extract
Skin ConditioningAsiaticoside
AntioxidantCaprylyl/Capryl Glucoside
CleansingHydrogenated Lecithin
EmulsifyingCeramide NP
Skin ConditioningAcetyl Hexapeptide-8
HumectantAscorbic Acid Polypeptide
AntioxidantAcetyl Octapeptide-3
HumectantAcetyl Tetrapeptide-2
Skin ConditioningAcetyl Tetrapeptide-3
Skin ProtectingAcetyl Tetrapeptide-5
HumectantAcetyl Tetrapeptide-9
Skin ConditioningCarnosine
Skin ConditioningCopper Tripeptide-1
Skin ConditioningNonapeptide-1
Skin ConditioningPalmitoyl Pentapeptide-4
Skin ConditioningPalmitoyl Tripeptide-1
Skin ConditioningPalmitoyl Tripeptide-5
Skin ConditioningWater, Butylene Glycol, Glycerin, 1,2-Hexanediol, Propanediol, Pentylene Glycol, Sodium Polyacryloyldimethyl Taurate, Ammonium Polyacryloyldimethyl Taurate, Panthenol, Biotin, Tromethamine, Acetyl Glucosamine, Sodium Phytate, Sodium Hyaluronate, Citric Acid, Hydroxyacetophenone, Cynanchum Atratum Extract, Sodium Hyaluronate Crosspolymer, Dipropylene Glycol, Biotinoyl Tripeptide-1, Caprylyl Glycol, Betaine, Madecassoside, Centella Asiatica Leaf Extract, Asiaticoside, Caprylyl/Capryl Glucoside, Hydrogenated Lecithin, Ceramide NP, Acetyl Hexapeptide-8, Ascorbic Acid Polypeptide, Acetyl Octapeptide-3, Acetyl Tetrapeptide-2, Acetyl Tetrapeptide-3, Acetyl Tetrapeptide-5, Acetyl Tetrapeptide-9, Carnosine, Copper Tripeptide-1, Nonapeptide-1, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-5
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative".
It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time.
The comparison to Botox does have limits because the molecule is water-loving and relatively large.
Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles.
So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging.
A 12 week human study of a multi-ingredient regimen containing this ingredient saw:
While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone).
Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations.
Learn more about Acetyl Hexapeptide-8Betaine is a humectant. Like hyaluronic acid, it helps attract and retain moisture in the skin. It’s known for being gentle and for helping the skin maintain balanced hydration.
Betaine is mainly used to improve hydration and support calmer skin. It helps skin cells regulate water balance because it functions as an osmolyte.
Some studies suggest betaine may support making skin tone more even.
Fun fact: Betaine naturally exists in the skin and the body. In cosmetic products, it can be either plant-derived (most commonly from sugar beets) or synthetically produced for consistency and stability.
Betaine is also known as trimethylglycine.
Learn more about BetaineButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolCaprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Learn more about Caprylyl GlycolCitric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
In skincare formulas, citric acid can:
While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
Read more about some other popular AHA's here:
Learn more about Citric AcidGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinHydroxyacetophenone is a small phenolic molecule that earns its place in a formulas as an antioxidant and preservative booster.
As a phenol, it is able to neutralize free radicals to protect both the product and the skin from oxidative stress.
Though it can't kill microbes on its own, it works as a good supporting agent when combined with other preservatives like Phenoxyethanol or 1,2-Hexanediol.
This ingredient naturally occurs as piceol in Norwegian spruce needles (~0.4-1.1% dry weight and in cloudberries). Though the cosmetic-grade material is synthesized for purity and consistency.
You'll usually see it used at low levels and suppliers recommend up to 1% added to a water phase.
Safety testing was done at concentrations like 0.05% in SPF products and 0.5% in a Human Repeated Insult Patch Test. The safety evidence is assuring; this ingredient is safe for cosmetics in current use and also holds safety status as a food flavoring as well.
An honest caveat: the "soothing" and "anti-inflammatory" claims come mostly from supplier marketing rather than published clinical trials. The Cosmetic Ingredient Review's own literature search found no useful efficacy studies on this ingredient.
So the antioxidant and preservative-boosting roles are the well supported ones while the calming benefit is plausible but thinly evidenced.
Overall, this is a well-tolerated, low-irritation multitasker that quietly helps a formula stay fresh and stable.
Learn more about HydroxyacetophenonePalmitoyl Tripeptide-5 is a synthetic signal lipopeptide. This just means it is a three amino acid chain bolted onto a palmitic acid tail so it can slip through the skin's lipid barrier.
This peptide has a "build more, lose less" approach.
It's designed to mimic the collagen-stimulating activity in your skin by copying a snippet of one of your skin's own matrix proteins. This nudges fibroblasts into making more collagen while inhibiting the enzyme that breaks down skin protein.
The manufacturer's in vivo study of 45 volunteers found 1% and 2.5% reduced the appearance of wrinkles by 7% and 12% respectively, after using it twice daily for 84 days.
This is in the expected range for peptides; they're slow and cumulative actives and not overnight fixers.
Typical use levels range from 1-3% and this ingredient gets along with pretty much everything.
On the fungal acne front:
Although palmitic acid sits in the chain length that Malassezia can feed on, this ingredient has it locked in an amine bond. This makes it hard for Malassezia to access as a source of food, and therefore fungal acne safe.
Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Learn more about PanthenolPentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:
Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.
On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.
Typical use levels in a formula run about 1-5%.
Learn more about Pentylene GlycolSodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Learn more about Sodium HyaluronateSodium Phytate is the synthetic salt form of phytic acid. Phytic acid is an antioxidant and can be found in plant seeds.
Sodium Phytate is a chelating agent. Chelating agents help prevent metals from binding to water. This helps stabilize the ingredients and the product.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water