The Originote Mugwort B3 Clay Stick Mask

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

The CIR Expert Panel has confirmed this ingredient to be nontoxic and clinical studies show no sensitization at cosmetic use concentrations.

True allergic reactions are quite rare: a 15-year retrospective study of 6,751 patients found only 0.31% had a positive reaction (and less than half were considered clinically relevant).

It seemed that when sensitization does occur, it's most commonly linked to topical medication (like corticosteroids) and not cosmetics. Allergic contact dermatitis also appears largely limited to individuals with underlying skin conditions.

Overall, propylene glycol is a well-studied ingredient that most people can tolerate without issue.

A really common myth is that mineral filters work by reflecting UV light off your skin like tiny mirrors.

They don't only do that; modern research shows TD protects mostly by absorbing UV radiation, the same way chemical filters do.

When researchers measured this, reflection accounted for only about 4-5% of the protection (and less than SPF 2 on its own). The other ~95% comes from absorption: the UV photons hit the particle and their energy gets soaked up by its semiconductor band gap rather than bouncing off.

So "reflects vs. absorbs" was never really the right way to split mineral from chemical filters.

TD gives broad-spectrum protection that's strongest in the UVB and UVA-2 range and weaker in the UVA-1 range. Its UVA protection isn't quite as strong as Zinc Oxide's which is why you'll often see the two paired together.

Together, they make a solid broad-spectrum system.

TD is a great pick for sensitive, acne-prone, or redness-prone skin because it's non-irritating and chemically inert. Regulatory reviews classify it as a non-sensitizer and mild-to-non-irritant.

It's also unlikely to cause the "eye sting" some chemical filters are known for.

The main trade-off is cosmetic; TD can leave a white cast and has a thicker texture. This is why mineral sunscreens are often less cosmetically elegant than chemical or hybrid formulas (and harder to shade-match on deeper skin tones).

Formulators often use micronized or nano-sized TD to cut down on white case and improve spreadability. Smaller particles scatter less visible light so the formula looks less chalky while still filtering UV.

TD is almost always bundled with coatings like Alumina, Silica, Stearic Acid, or Dimethicone. These coatings do two important jobs:

TD can be used at up to 25% in a finished sunscreen; this is the regulatory ceiling in both the US and the EU.

In practice, the amount in any given product varies a lot depending on the target SPF and whether it's paired with other UV filters.

TD is one of the most heavily vetted sunscreen ingredients out there. It is approved as a UV filter in all major markets worldwide, including the US, EU, UK, Japan, Korea, China, Australia, and Canada.

The safety evidence is solid. There was an old worry that nano particles might absorb through skin into the body but multiple studies (including on damaged, sunburned, and UV-irradiated skin) have shown that TD stays on the surface and the layer of dead skin cells on top of everything else.

There's also no evidence of carcinogenicity, mutagenicity, or reproductive toxicity from dermal exposure of this ingredient.

For those who have seen the headline about a 2022 EU ban on TD, that was on TD as a food additive (a complete separate use from topical sunscreen).

There are ongoing questions about how nano-TD might affect marine ecosystems. As of now, there has been no conclusive evidence that any form of TD (or any other sunscreen filter) harms coral reefs or marine life.

The science is still developing and it's a space worth watching rather than packing over.

However, several destinations have reef-safety sunscreen rules that restrict certain chemical filters and steer visitors toward mineral, non-nano options. If you're traveling somewhere with these rules, a non-nano mineral sunscreen is the safe bet.

It is soluble in water. The number '8' stands for the molecular weight of the ingredient.

Irritation is rare at normal concentrations and it doesn't penetrate deeply into skin.

The unique structure of silica enhances the spreadability and adds smoothness, making it a great texture enhancer.

It is also used as an active carrier, emulsifier, and mattifier due to its ability to absorb excess oil.

In some products, tiny microneedles called spicules are made from silica or hydrolyzed sponge. When you rub them in, they lightly polish away dead skin layers and enhance the penetration of active ingredients.

Synthetically created CI 77492 is considered safer than those naturally found. This is because the synthetically created version may contain less impurities. Iron oxides are generally non-toxic and non-allergenic.

This ingredient is often coated with metal oxides like titanium dioxide. Trace amounts of heavy metals may be found in mica, but these metals are not harmful in our personal products.

Mica has been used since prehistoric times throughout the world. Ancient Egyptian, Indian, Greek, Roman, Aztec, and Chinese civilizations have used mica.

One of its most common jobs is acting as a pigment carrier and dispersant.

Alumina platelets are often blended with inorganic sunscreens like Titanium Dioxide (or with colorants) and then coated with a silicone such as Triethoxycaprylylsilane so the pigment spreads evenly and smoothly.

In makeup, it can also double as a light-diffusing powder or oil absorber to keep formulas from looking greasy.

The Cosmetic Ingredient Review Expert Panel has concluded alumina to be safe in present practices of use and concentration.

They note it's a stable, oxidized compound and scientific research has failed to establish links to health issues.

Concentrations vary depending on the product:

Chlorphenesin is soluble in both water and glycerin.

Studies show Chlorphenesin is easily absorbed by our skin. You should speak with a skincare professional if you have concerns about using Chlorphenesin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Salicylic acid is also known for its soothing properties. It has a similar structure to aspirin and can calm inflamed or irritated skin, making it a good option for acne-prone skin that is also sensitive.

Concentrations of 0.5-2% are recognized by the U.S. FDA as an over-the-counter topical acne product.

It can cause irritation and/or dryness if one's skin already has a compromised moisture barrier, so it's best to focus on repairing that before introducing this ingredient into your routine.

While salicylic acid does not increase sun sensitivity, it’s still important to wear sunscreen daily to protect your skin.

If you are looking for the ingredient called BHA or Butylated Hydroxyanisole, click here.

For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.

The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.

For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.

One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.

Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.

Parfum can also be used to mask or cover an unpleasant scent.

The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.

Menthol also has antimicrobial properties.

These compounds allow centella to dial back inflammation, encourage the skin to build and hold onto collagen, support the barrier and hydration, and bring solid antioxidant activity to protect against signs of aging.

Centella also carries a nice supporting cast of Vitamin A, vitamin C, several B vitamins, and amino acids. Put it all together and you get an ingredient that soothes, hydrates, and protects, all at once.

Most of centella's magic comes from the four big compounds (Asiaticoside, Madecassoside, Asiatic Acid, and Madecassic Acid). These are the actives doing the heavy lifting in almost every centella study.

Here is the short version of what they do in the skin:

So it is not just soothing for the sake of soothing. Centella calms the skin AND helps it rebuild.

Just FYI, not all centella on an ingredient list is the same. What you are getting actually depends on the extract:

Fun fact on the ratios: the leaves tend to be richest in Madecassoside and Asiaticoside, and lower in the two acids. The exact amounts shift with where the plant is grown and how it is processed. This means purity really does vary brand to brand.

Centella is one of the most easygoing actives out there.

It layers well with basically everything: niacinamide, hyaluronic acid, peptides, and vitamin C, and also pairs nicely with stronger actives like retinoids and exfoliating acids where it can help take the edge off irritation.

On the safety side, centella and its triterpenes are classified as weak sensitizers, meaning allergic reactions are possible but uncommon.

Patch tests at 1% and 5% came back negative in test panels, and creams at typical use levels did not cause allergic reactions across large groups of people.

But as with any new active, a patch test is still a smart move for very reactive skin.

Centella is widely used because it is effective at low percentages. For context, human safety testing found no meaningful irritation from creams containing centella extract at everyday use levels (the tested amounts were well under 1%).

The irritancy threshold in animal testing was also above 30% (so real-world formulas sit far below anything concerning).

In collagen lab studies, higher concentrations drove more collagen synthesis, so serums built around centella tend to feature it more prominently.

Bottom line: you will find centella working nicely anywhere from a fraction of a percent up to hero-ingredient levels depending on whether it is a supporting soother or the main event.

Fun fact: Centella has been used as a medicine and in food for many centuries. As a medicine, it is used to treat burns, scratches, and wounds.

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

The zinc part slows down an enzyme that turns testosterone into DHT, the hormone that tells your oil glands to pump out more sebum. Less of that signal means less oil. It also gently fights acne-causing bacteria and soothes redness/irritation.

This is why Zinc PCA often shows up in products for oily, breakout-prone skin and greasy scalps.

One lab study also hinted it might have a small anti-aging perk because it seemed to protect collagen from UVA damage and even helped the skin make a bit more of it. That last bit is still early research done in a dish and not real skin, so take it as a nice bonus rather than a promise for now.

As for scar healing, the picture is more "maybe" than a firm yes. Zinc itself plays a real role in wound repair because it is a cofactor for the enzymes involved in collagen building, calming inflammation, and helping new skin cells cover a wound. Lower zinc levels are also linked to slower healing.

Most of the scar healing research is on zinc oxide or oral zinc rather than zinc PCA specifically, with a focus on healing fresh wounds instead of scars that are already there.

Direct evidence that zinc PCA improves the look of established scars is still limited at this time. Though it would be fair to say zinc PCA supports the general skin-repair environment thanks to its zinc content .

This ingredient is water-soluble and plays nicely with other actives like niacinamide and salicylic acid. It works best at mildly acidic formulas (~4-6 pH) and is effective at low levels. Around 0.1% is enough to be active and finished products commonly use it anywhere up to 4%.

Overall, this is a well-tolerated, low-drama multitasker that suits oily and acne-prone skin.

Your skin can't convert salicin to salicylic acid because it needs specific enzymes that aren't present on the skin's surface. It won't behave like true salicylic acid, especially at the concentrations used in cosmetics.

However, this ingredient has its own perks. It contains flavonoids, polyphenols, and tannins that give it proven antioxidant and soothing properties.

An 8-week clinical study found a cream with 2% of this extract improved skin microcirculation, elasticity, and dark circles. This is most likely due to its role in increasing hyaluronic acid synthesis in fibroblasts and improved vascular integrity.

Another study found a topical serum with 0.5% salicin showed improvements in visible signs of aging, hyperpigmentation, and texture.

Just be careful if you have a known aspirin/salicylate allergy and be sure to consult with a medical professional about using this ingredient if you do.

Fun fact: Willow Bark extract has been used for thousands of years and ancient civilizations used white willow to help treat pain and fevers.

A clinical study found that applying 0.5% bisabolol daily for 8 weeks produced an average 9% decrease in skin pigmentation. Researchers found it can also suppress the process that leads to excess melanin production in skin.

In vitro studies found that bisabolol combined with propylene glycol significantly increased skin permeability by increasing lipid fluidity in the stratum corneum.

You'll likely see use concentrations quite low, usually 0.1-0.2%.

Overall, this is a well-tolerated ingredient that works well in formulas designed for sensitive, reactive, or post-procedure skin.

Research shows it can help:

It also pairs nicely with hydrating ingredients like niacinamide and ceramides.

Just so you know, Propolis Extract is recognized as a contact allergen. In patch tests done in the EU, roughly 1-6% of patients react to it. Be sure to steer clear of this ingredient if you have a known allergy to bee products.

Since it is an animal-derived product, this ingredient is not considered vegan. For vegan alternatives, check out Galactomyces Ferment Filtrate or Centella Asiatica Extract.

This is why Europe's medicines regulator has approved calendula extracts as a traditional remedy for minor skin inflammation and healing small wounds.

The stronger human evidence is around would/ulcer care rather than everyday cosmetic claims; a review that pulled together 14 studies found that calendula helped calm the early, inflamed stage of a wound and helped new skin tissue form faster.

Two studies also showed it shrank leg ulcers (the kind caused by poor circulation). Results were mixed for burns and for the skin irritation people get from radiation treatment, so it's not a sure thing there.

In cosmetics, it's mostly a skin conditioning and soothing agent.

The Cosmetic Ingredient Review panel concluded that calendula-derived ingredients are safe as used and that the ingredients are not irritating, sensitizing, or photosensitizing in clinical tests (though they may be mild eye irritants).

Typical use levels are quite low; industry data reported it used at under 0.5% (one supplier noted a 10-25% extract blend used at 1-10% in the finished product). Historical use goes up to 10%.

The only thing to keep in mind is if you have daisy/ragweed allergies. Calendula is in the same family and one patch-test study found 2% of dermatitis patients reacted to marigold. Be sure to patch test if you have sensitive or allergy-prone skin.

Caprylhydroxamic Acid is often used with natural antimicrobial products as an alternative to preservatives.