Perricone MD Cold Plasma Plus+ Daily Detox Cleanser

Perricone MD Cold Plasma Plus+ Daily Detox Cleanser

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Overview

What it is

Face cleanser with 40 ingredients that contains exfoliants, peptides and zinc

Cool Features

It is cruelty-free and reef safe

Suited For

It has ingredients that are good for fighting acne, anti aging, dry skin, sensitive skin, oily skin, reducing pores and scar healing

Free From

It doesn't contain any harsh alcohols, common allergens, fragrances, parabens or sulfates

Fun facts

Perricone MD is from United States. This product is used in 3 routines created by our community.

We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.

What's inside

Ingredients List

Key Ingredients

Benefits

Concerns

Ingredients Explained

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Learn more about Water
Abrasive, Absorbent, Cosmetic Colorant

Kaolin is a clay. It is used for oil control and to help minimize pores. Like other clays, kaolin has the ability to absorb excess sebum or oil. This can help clean out pores and mattify the skin.

Some types of kaolin may have exfoliating properties. When water is added to kaolin, it becomes a paste with small abrasive particles.

Most kaolin is a white color, but may be pink/orange/red depending on where it comes from.

The name 'kaolin' comes from a Chinese village named 'Gaoling'. Kaolin clay comes from rocks rich in kaolinite. Kaolinite, the mineral, has a silicate layered structure. Kaolinite is formed from chemical weathering of aluminum siilicate minerals.

Besides skincare, kaolin is commonly used to make glossy paper, in ceramics, toothpaste, and as medicine to soothe stomach issues.

Learn more about Kaolin
Masking, Skin Conditioning

This ingredient is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.

It helps thicken a product's formula and makes it easier to spread by dissolving clumping compounds.

Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid. Though it behaves like an oil, it is not technically one due to its chemical composition. It is very stable, resistant to oxidation, and unlikely to go rancid. In practice, that translates to a long shelf life and a consistently elegant skin feel.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Be sure to patch test if you have concerns.

Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.

Learn more about Caprylic/Capric Triglyceride
Humectant, Skin Conditioning, Skin Protecting

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Emollient, Emulsifying

Glyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.

Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.

This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.

A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.

Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.

Fun fact: The human body also creates Glyceryl Stearate naturally.

Learn more about Glyceryl Stearate
Emollient, Emulsifying, Emulsion Stabilising

Cetyl Alcohol is a fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product.

Its main roles are:

Though it has "alcohol" in the name, it is not related to denatured alcohol or ethyl alcohol.

The FDA allows products labeled "alcohol-free" to have fatty alcohols.

Learn more about Cetyl Alcohol
Absorbent, Emulsion Stabilising

Bentonite is an aluminium phyllosilicate clay with great absorbent properties. The name 'bentonite' comes from the area where the largest source is found: Fort Benton, Wyoming.

As a clay, bentonite is often used to absorb excess oil and provide exfoliation. It has also been shown to have some antibacterial and anti-inflammatory properties. Studies show bentonite was effective at calming dermatitis from poison ivy and in diaper dermatitis of infants. Bentonite has also been shown to act as a barrier against toxic compounds on your skin.

Sunscreens containing bentonite display higher water resistance and stay on the skin for much longer. The sunscreens containing bentonite also show higher potency and UV light absorbtion.

Bentonite is naturally created from volcanic ash and several natural weathering/hydrothermal processes.

A common usage of bentonite is removing excess protein from white wines. Bentonite contains a property of being able to absorb large amounts of protein from aqueous solutions.

Phyllosilicate clay has a structure formed by sheets.

Learn more about Bentonite
Humectant, Skin Conditioning, Soothing

Sucrose is a natural sugar found in fruits, vegetables, and nuts. It is the main constituent of white sugar.

In skincare, sucrose is a humectant and can be a mild exfoliant.

Sucrose is hydrophilic, meaning it attracts water. This makes it an effective humectant and helps hydrate the skin.

Studies show sugars may worsen acne-prone skin due to it disrupting the skin's natural biome. We recommend speaking with a professional if you have any concerns.

In some products such as body scrubs, sucrose is used as an gentle exfoliant.

The term 'sucrose' comes from the french word for sugar, 'sucre'.

Learn more about Sucrose
Emulsion Stabilising

We don't have a description for Sodium Carboxymethyl Starch yet.

Emollient, Skin Conditioning, Skin Protecting

Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Learn more about Dimethicone
Skin Conditioning

Though this ingredient might sound like a juicy fruit extract, it's actually the fat pressed from the mango seed kernel (or the pit). In skincare, it behaves more like shea butter and cocoa butter than like a plant active.

The fatty acid makeup of mango seed butter makes it special; it's typically rich in stearic acid and oleic acid, with small amounts of palmitic and linoleic acid. This combo helps it melt on skin, feel creamy, and leave behind a protective "seal" that slows down water loss.

It also contains a small amount of "extras" like tocopherols (vitamin E) and phytosterols, which are often used to support skin soothing.

Due to its fatty acid content, this ingredient may not be fungal acne safe.

Learn more about Mangifera Indica Seed Butter
Emollient, Masking, Skin Conditioning

Helianthus Annuus Seed Oil is a plant oil derived from the seeds of a sunflower.

It is rich in fatty acids, primarily linoleic acid and oleic acid. This gives it emollient and skin conditioning properties.

The reason this ingredient is so effective is because it forms a thin film on the skin that reduces transepidermal water loss (TEWL) while supplying linoleic acid to the stratum corneum to improve barrier strength.

The high linoleic acid content is particularly noteworthy for acne-prone skin.

Research suggests that acne-prone skin tends to be deficient in linoleic acid in sebum. Topical application may help replenish this to support a healthier follicular environment and less comedone-promoting sebum.

One randomized study found sunflower seed oil preserved skin barrier integrity in adult volunteers with and without atopic dermatitis (outperforming olive oil).

This ingredient is well-studied, gentle, and an effective emollient suitable for most skin types.

On fungal acne: This ingredient may not be Fungal acne (Malassezia folliculitis) safe. This is because it contains fatty acids with carbon chain lengths in the C11-C24 range.

Learn more about Helianthus Annuus Seed Oil
Preservative

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

Abrasive, Absorbent

Charcoal powder comes from grounded charcoal. Charcoal can originate from peat, bamboo, coal, wood, coconut shell, or petroleum.

This ingredient has absorbent properties, making it great at absorbing oil.

Skin Conditioning, Solvent

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. 

It is a:

  • Humectant, drawing moisture into the skin
  • Emollient, helping to soften skin
  • Solvent, dispersing and stabilizing formulas
  • Preservative booster, enhancing the antimicrobial activity of other preservatives 
Cleansing, Emulsifying, Skin Conditioning

Sodium Stearoyl Glutamate is an amino-acid based emulsifier. It is made by combining stearic acid with L-glutamic acid and neutralizing it to a sodium salt.

As an emulsifier, it works mainly as an oil-in-water one and helps keep the oil and water in your formulas blended. It also contributes to a smooth, non-greasy skin feel.

This ingredient is biodegradable and commonly available in natural/COSMOS-certified grades.

Learn more about Sodium Stearoyl Glutamate
Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Learn more about Butylene Glycol
Absorbent, Skin Protecting

Zea Mays Starch is starch made from corn. You might know this as cornstarch . It is used to thicken a product. It can replace talc as an absorbent.

The pH of cornstarch is 5.92.

Cornstarch is a common food ingredient used to thicken soups or to make corn syrup.

Learn more about Zea Mays Starch
Skin Protecting

We don't have a description for Salix Nigra Bark Extract yet.

We don't have a description for Myristamidopropyl Pg-Dimonium Chloride Phosphate yet.

Avena Sativa Bran Extract comes from oatmeal. The bran is the shell covering the oat.

This ingredient is an abrasive, meaning it exfoliates the top layer of your skin.

Sodium Phytate is the synthetic salt form of phytic acid. Phytic acid is an antioxidant and can be found in plant seeds.

Sodium Phytate is a chelating agent. Chelating agents help prevent metals from binding to water. This helps stabilize the ingredients and the product.

Skin Conditioning

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Learn more about Ethylhexylglycerin

Hippophae Rhamnoides Seed Oil comes from the seeds of the seabuckthorn plant.

Seabuckthorn is rich in phytosterols, carotenoids, Vitamins A, C, and E. This gives it strong antioxidant properties that can help soothe and protect your skin from oxidative damage.

The seeds of seabuckthorn are rich in fatty acids. These include linoleic acid (~30-34%), oleic acid (17%), and palmiteic acid (35%).

Palmitoleic acid has been shown to help soothe inflammation and promote wound healing. It is also naturally found in the fat of our skin.

Learn more about Hippophae Rhamnoides Seed Oil
Skin Conditioning

Copper Tripeptide-1 (GHK-Cu) is a skin repairing ingredient known for its ability to boost collagen, improve firmness, and support skin regeneration.

It is a complex made up of a naturally occurring peptide (glycine-histidine-lysine) and copper, an essential trace element.

While studying wound healing, researchers noticed GHK-Cu stimulated hair follicle enlargement and growth by keeping hair in its active growth phase longer. This has made it a promising ingredient for hair regrowth treatments.

Some people have reported increased facial hair. While GHK-Cu can make your hair follicles bigger, it usually doesn’t turn soft, barely-visible facial hairs into thick, dark ones.

Anecdotal reports suggest that overusing copper peptides might lead to premature aging due to excess free copper or enzyme imbalances. This claim isn’t backed by large-scale studies.

Unfortunately, there are limited human studies for this ingredient. While early results are promising, many studies are either small, in-vitro, or not rigorously controlled.

For example, there is a 1998 study that explored the effects of copper tripeptide, vitamin C, tretinoin, and melatonin on skin repair and collagen synthesis.

After one month, increased procollagen production was seen in 7 out of 10 participants using copper tripeptide (more than those using vitamin C, melatonin, or tretinoin.

While the study was exploratory, it offers early evidence that copper tripeptide may support collagen production. Larger, well-designed trials are still needed to confirm its potential and understand individual responses.

Read more about other common types of peptides here:

Learn more about Copper Tripeptide-1
Buffering, Masking

Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.

Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.

However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.

Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.

In skincare formulas, citric acid can:

While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.

Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.

Read more about some other popular AHA's here:

Learn more about Citric Acid
Emulsion Stabilising

This ingredient is a semi-synthetic polymer created from cellulose. In case you need a refresher, cellulose is the main component of plant cell walls.

Hydroxypropyl Methylcellulose has many uses:

  • emulsifier
  • create a gel-like texture
  • boost foam
Antimicrobial, Masking, Skin Conditioning

This is a botanical extract from the rosemary plant (the same one you cook with). In skincare, it mostly works as a skin conditioning agent.

Its activity comes from a handful of polyphenols, carnosic acid, carnosol, and rosmarinic acid. Almost 90% of the antioxidant activity of this ingredient can be attributed to canosol and carnosic acid.

These compounds protect your skin two ways:

1) They fight off free radicals, or the unstable molecules from things like sun and pollution that age and damage skin.
2) They help calm inflammation by switching off the chemical signals that tell skin to get red and irritated.

Lab studies also suggest that rosmarinic acid may help protect collagen and slow sugar-related damage to it.

The Cosmetic Ingredient Review has concluded rosemary-derived ingredients to be safe when formulated to be non-sensitizing.

Rosemary can occasionally cause allergic contact dermatitis (due to carnosol), so be sure to patch test if you have reactive or fragrance-sensitive skin.

Learn more about Rosmarinus Officinalis Leaf Extract

We don't have a description for Epilobium Angustifolium Flower/Leaf/Stem Extract yet.

Skin Conditioning

We don't have a description for Magnesium Aspartate yet.

Skin Conditioning

Zinc gluconate has antibacterial and wound healing properties. It is particularly effective against fighting inflammatory acne.

This ingredient is the zinc salt of the PHA gluconic acid. PHAs are gentle cousins to AHAs.

We don't have a description for Polyvinyl Alcohol yet.

Leuconostoc/Radish Root Ferment Filtrate is a natural preservative. It comes from fermenting radish roots with a bacteria called leuconostoc. The trade name for this ingredient is Leucidal.

Leuconostoc comes from lactic acid.

This ingredient has antimicrobial properties and helps prevent the growth of bacteria in a product.

Leuconostoc is used to make the traditional Korean side-dish, kimchi. It is also used to make sourdough bread (both incredibly yummy foods).

Learn more about Leuconostoc/Radish Root Ferment Filtrate
Abrasive

Quartz is a hard mineral made of silica. In cosmetics, quartz helps exfoliate the skin.

In cosmetic tools, it is usually a polished stone-like material.

Skin Conditioning, Skin Protecting

This ingredient is a copper salt known for its wound healing properties.

Our bodies use copper to help stabilize our skin's collagen and elastin. Its also an essential for superoxide dismutase, an enzyme with strong antioxidant properties.

Copper has wound healing properties due to its role in creating new blood vessels and tissue repair.

Learn more about Copper Gluconate
Antioxidant, Preservative

Sodium metabisulfite is also known as Sodium Pyrosulfite. It is a preservative, antioxidant, and disinfectant.

As a preservative, it helps stabilize cosmetic formulas without affecting their color or scent.

Triethoxycaprylylsilane is a silicon-based surface modifier that makes sunscreens feel silky and makeup stay put.

Its main job is to coat mineral particles like titanium dioxide, zinc oxide, and color pigments in a thin, oily layer so they spread smoothly, don't clump, and stick to skin better.

This ingredient is typically used at low levels (up to 2.5% in eyeshadow and 1% in lipstick).

Learn more about Triethoxycaprylylsilane
Cosmetic Colorant

Ci 42090 is a synthetic dye created from petroleum. It is used to give a bright blue color to cosmetics, medicine, and food.

Cosmetic Colorant

Ci 77499 is also hydrated iron III oxide. It is created from mixing red and black iron oxides. This helps give shades of darkness to a product.

Iron III oxides are classified as inorganic chemicals for coloring.

Cosmetic Colorant

This pigment is called Ultramarine blue lazurite. It gives a saturated blue color, but can be used to create other colors as well.

According to the manufacturer, it is usually made from kaolin, sodium sulfate, sodium carbonate, sulfur, and charcoal.

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Where it's from

Perricone MD is a American brand

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· Updated September 17, 2025 Added by joyceakiko