Nano White Spot Correction Mattifying Moisturizer
A moisturizer with 36 ingredients, including vitamin C, niacinamide, and vitamin E.
This brightening moisturizer is formulated around Ascorbyl Glucoside and Niacinamide to fade the look of dark spots and balance excess oil.
Worth noting
Contains drying alcohol, which absorbs quickly but can be dehydrating.
We independently verify ingredients, backed by peer-reviewed research. Suggest an update.
What's inside
Ingredients List
Water
Skin ConditioningPolyacrylamide
Caprylic/Capric Triglyceride
MaskingDimethicone
EmollientC13-14 Isoparaffin
EmollientPhenoxyethanol
PreservativeMethylparaben
PreservativePropylene Glycol
HumectantEthylparaben
PreservativeParfum
MaskingLaureth-7
EmulsifyingHamamelis Virginiana Leaf Water
AstringentPanax Ginseng Root Extract
EmollientDiazolidinyl Urea
PreservativeEthoxydiglycol
HumectantAscorbyl Glucoside
AntioxidantNiacinamide
SmoothingInulin
Skin ConditioningButylene Glycol
HumectantSodium Hydroxide
BufferingChamomilla Recutita Flower Extract
MaskingGlucose
HumectantLactic Acid
BufferingAlpha-Glucan Oligosaccharide
CleansingAlcohol
Antimicrobial4-Terpineol
MaskingLecithin
EmollientIodopropynyl Butylcarbamate
PreservativeLaminaria Saccharina Extract
Skin ProtectingArbutin
AntioxidantBisabolol
AntioxidantTocopheryl Acetate
AntioxidantGlutathione
Linolenic Acid
CleansingLinoleic Acid
CleansingAscorbyl Palmitate
AntioxidantWater, Polyacrylamide, Caprylic/Capric Triglyceride, Dimethicone, C13-14 Isoparaffin, Phenoxyethanol, Methylparaben, Propylene Glycol, Ethylparaben, Parfum, Laureth-7, Hamamelis Virginiana Leaf Water, Panax Ginseng Root Extract, Diazolidinyl Urea, Ethoxydiglycol, Ascorbyl Glucoside, Niacinamide, Inulin, Butylene Glycol, Sodium Hydroxide, Chamomilla Recutita Flower Extract, Glucose, Lactic Acid, Alpha-Glucan Oligosaccharide, Alcohol, 4-Terpineol, Lecithin, Iodopropynyl Butylcarbamate, Laminaria Saccharina Extract, Arbutin, Bisabolol, Tocopheryl Acetate, Glutathione, Linolenic Acid, Linoleic Acid, Ascorbyl Palmitate
Key Ingredients
Benefits
Concerns
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterPolyacrylamide is a synthetic polymer. It is used to stabilize products and bind ingredients. When hydrated, Polyacrylamide forms a soft gel.
Polyacrylamide is low-toxicity. If source properly, it is deemed safe to use in cosmetics.
It should be noted the precursor to Polyacrylamide is acrylamide. Acrylamide is a carcinogen. Most reputable sources of Polyacrylamide will screen for residual acrylamide to make sure the count is in a safe range. Acrylamide is not able to be absorbed through the skin.
We recommend speaking with a professional if you have concerns.
Learn more about PolyacrylamideCaprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.
Learn more about Caprylic/Capric TriglycerideDimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Learn more about DimethiconeC13-14 Isoparaffin is a synthetic emollient, solvent, and thickening agent. It helps soften skin and improves spreadability without leaving a greasy residue.
This ingredient has been found to be non-sensitizing and safe for use in cosmetics.
Two things floating around online that cause fear-mongering:
There's one scary-sounding study related to kidney tumors in male rats; this depends on a protein called alpha-2u-globulin that binds the ingredient and clogs up kidney cells. Female rats barely make this protein, and humans don't make it at all so this effect cannot happen to us. Regulatory bodies have states this rat-only pathway shouldn't be used to judge human risk.
The other thing you'll see is 1,4-dioxane being a trace byproduct that can form during manufacturing of petroleum-derived ingredients. This is a real, but heavily managed/monitored issue. This byproduct is removed through purification steps before the ingredients goes into the formula. Regulatory bodies also actively monitor residual levels for safety.
One last thing to note: this ingredient is a pure hydrocarbon with no fatty-acid or ester chains for Malassezia to feed on, so it's considered fungal acne safe.
Learn more about C13-14 IsoparaffinPhenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Learn more about PhenoxyethanolMethylparaben is a synthetic preservative and one of the most widely used in the world. It has a simple, but important job: prevent your products from going bad by stopping bacteria, yeast, and mold from growing.
Typical use levels are low, often 0.1-0.3%.
This is also one of the most heavily studied preservatives out there and major regulatory bodies have repeatedly given it the green light.
In 2023, the EU's Scientific Committee on Consumer Safety (SCCS) confirmed that this ingredient is safe up to 0.4% on its own, of up to 0.8% when mixed with other paraben esters.
Here's the science behind the noise behind parabens/hormones as well:
Methylparaben shows very weak estrogen-like activity in vitro tests (more than 1,000x weaker than your body's own estradiol). In vivo (live-organism) studies don't support a meaningful endocrine-disrupting effect either.
You get a stronger estrogenic effect from eating tofu, actually.
It's also a low sensitizer and allergic reactions are uncommon; they usually happen on damage or broken skin.
There is a caveat: France has proposed to formally re-examine its endocrine classification in 2025 so the regulatory conversation isn't fully closed as of yet.
But as it stands today, this ingredient is considered safe at permitted levels.
Learn more about MethylparabenPropylene Glycol is a synthetic, colorless, odorless liquid that has been a staple in cosmetics for decades. It is a skin conditioning agent, humectant, and solvent.
As a humectant, it draw water to the skin to reduce flaking and restore suppleness. It's also a solvent that helps dissolve other actives and keeps formulas stable across temperature changes.
The CIR Expert Panel has confirmed this ingredient to be nontoxic and clinical studies show no sensitization at cosmetic use concentrations.
True allergic reactions are quite rare: a 15-year retrospective study of 6,751 patients found only 0.31% had a positive reaction (and less than half were considered clinically relevant).
It seemed that when sensitization does occur, it's most commonly linked to topical medication (like corticosteroids) and not cosmetics. Allergic contact dermatitis also appears largely limited to individuals with underlying skin conditions.
Overall, propylene glycol is a well-studied ingredient that most people can tolerate without issue.
Learn more about Propylene GlycolEthylparaben is a preservative, is a paraben, and is not reef safe.
Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.
Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.
For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.
The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.
For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.
One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.
Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.
Parfum can also be used to mask or cover an unpleasant scent.
The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.
Learn more about ParfumLaureth-7 is created by the ethoxylation of lauryl alcohol using ethylene oxide. Lauryl alcohol is a fatty alcohol with hydrating properties.
This ingredient is an emulsifier and cleansing ingredient. As an emulsifier, it is used to prevent ingredients from separating. It also helps cleanse the skin by gathering dirt, oil, and pollutants to be rinsed away.
Hamamelis Virginiana Leaf Water comes from the witch hazel plant. The witch hazel plant is native to eastern North America.
Witch Hazel is an astringent, anti-inflammatory, antioxidant, and antibacterial ingredient. The tannin in witch hazel has a drying effect when used on skin and constricts proteins. This helps minimize the look of large pores temporarily.
The tannins and the fragrance components may be skin sensitizing.
Learn more about Hamamelis Virginiana Leaf WaterGinseng root is a well-loved ingredient in Asian skincare for good reason. It hydrates the skin, soothes irritation, and helps even out skin tone.
In traditional East Asian medicine, ginseng has been used for centuries both as food and as a healing remedy, and modern research continues to confirm its skin benefits.
One of the standout features of ginseng is its ability to improve blood circulation and oxygen delivery to the skin, bringing a fresh supply of nutrients to support overall skin health. It also has antioxidant and anti-inflammatory properties. This helps to protect your skin against damage from UV exposure, pollution, and daily stress.
Additionally, studies suggest that ginseng may help reduce hyperpigmentation by inhibiting tyrosinase, the enzyme involved in melanin production.
There are different types of ginseng used in skincare, and while they all share core benefits, their potency can vary.
Most products use fresh or white ginseng because it’s more affordable. However, red ginseng, produced by steaming the root, contains higher levels of ginsenosides, which are compounds with proven anti-aging effects. These ginsenosides help reduce the appearance of wrinkles and improve skin elasticity.
Note: All forms of ginseng are listed simply as “Panax ginseng” in ingredient lists. We recommend reaching out to the brand if you have questions about which type of ginseng is used in their ingredients.
For general antioxidant benefits, any ginseng extract will do, but for wrinkle care or firmer skin, red or fermented ginseng is often more effective.
In short, ginseng is a powerhouse ingredient that supports hydration, radiance, and resilience.
Learn more about Panax Ginseng Root ExtractDiazolidinyl Urea is an antimicrobial preservative. It is commonly used to prevent bacterial, yeast, and mold growth.
Diazolidinyl Urea slowly breaks down into formaldehyde, an effective microbe killer but also a known allergen/carcinogen.
Some people who are allergic to imidazolidinyl urea also react to diazolidinyl urea. It ranked as the 14th most common allergen in patch tests from 2005–06.
Safety reviews show that at concentrations under 0.5%, the formaldehyde released remains below the accepted safety limit, making it considered safe for cosmetic use.
Ultimately, its safety depends on individual skin sensitivity and personal comfort with formaldehyde-releasing preservatives.
Learn more about Diazolidinyl UreaEthoxydiglycol (aka Diethylene Glycol Monoethyl Ether) is one of the cosmetic world's quiet problem solvers.
In a formula, it is a solvent that dissolves tricky ingredients that don't want to mix in and helps spread ingredients evenly across your skin without leaving a greasy or sticky feeling
This makes it great for hard-to-dissolve actives like vitamin C, benzoyl peroxide, and self-tanner DHA.
It also has mild humectant and penetration enhancer abilities so it can help some actives absorb a little deeper.
The penetration boost is backed by lab research: studies using human skin samples found it improved how well an active dissolves into the upper layer of skin rather than tearing down your skin barrier. Reviews of its mechanism also describe it interacting gently with the lipids and water in your outermost layer of skin.
Just know this penetration-enhancing effect is not universal. It helps a lot in some formulas and did very little in others (so the benefit really depends on the specific product).
Safety-wise, the evidence is reassuring. The Cosmetic Ingredient Review Expert Panel reviewed it and concluded it's safe for use in cosmetics and recognized it as non-irritating, non-sensitizing, and non-comedogenic in skincare.
Typical leave-on skincare usage lands around 1-10%. The EU has sets caps of 2.6% in non-spray products, 10% in rinse-offs, 7% in oxidative hair dye, and 5% in non-oxidative hair dye.
Learn more about EthoxydiglycolAscorbyl Glucoside (AA-2G) is one of the most stable vitamin C derivatives out there.
It's made by attaching a glucose molecule to ascorbic acid; this glucose "cap" shields the vitamin C from air, light, heat, and metal ions that normally cause pure ascorbic acid to oxidize.
Once on your skin, the enzyme alpha-glucosidase snips off the glucose and gradually releases active ascorbic acid right where it's needed. Basically, it behaves like a slow-release pro-vitamin C with less of a stinging that high-strength ascorbic acid can cause.
The research supports the classic vitamin C benefits as well. In lab and human studies, AA-2G slowed down the skin's production of melanin (the pigment behind dark spots) and helped shield skin cells against sun damage better than ascorbyl phosphate.
These studies also showed AA-2G released vitamin C over a longer period.
A frequently cited manufacturer trial found that a 2% AA-2G face cream significantly improved wrinkle depth and skin roughness after 45 days.
And in 2009, a clinical trial showed it meaningfully lightened dark patches on the gums compared to a placebo.
There's also collagen-synthesis support (since vitamin C is a required cofactor for that) and an antioxidant effect too.
Typical usage is usually between 0.5-5% and most studies/products land around 2%.
AA-2G performs best when formulated at a mildly acidic pH (~5-7) which is much gentler than the pH that pure vitamin C demands (~2.5-3.5).
Just one thing worth knowing: the in-skin conversation rate is only about 55-60% by weight. So a 5% AA-2G product delivers roughly 2.75-3% of actual active vitamin C. On top of that, skin absorption is relatively low because the ingredient is water-soluble.
Learn more about Ascorbyl GlucosideNiacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Learn more about NiacinamideInulin is a polysaccharide (carbohydrate) with prebiotic and antioxidant properties.
The majority of inulin is extracted from chicory, but can also be obtained from other plants such as garlic, onion, asparagus, and sugarcane.
Studies show inulin may help with controlling your skin's natural microbiota when applied topically.
The antioxidant potential of inulin varies depending on the source.
Learn more about InulinButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolSodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Learn more about Sodium HydroxideChamomilla Recutita Flower Extract comes from the Chamomile flower.
Chamomile is rich in antioxidants and has anti-inflammatory properties. Several compounds found in chamomile help with soothing, such as bisbolol.
Antioxidant components in chamomile make it an effective ingredient to help slow the signs of aging. Antioxidants help fight free-radical molecules, or molecules that may damage your skin.
Essential oils from chamomile have been found to improve wound healing due to its antimicrobial properties.
Ancient Greeks and Egyptians used Chamomile to treat skin redness and dryness. Chamomile has also been used to help treat stomach issues.
Learn more about Chamomilla Recutita Flower ExtractGlucose is a simple sugar (a monosaccharide). In skincare, it is mostly a humectant and skin conditioning agent.
Mechanistically, it has multiple hydroxyl groups that hydrogen-bond to water. This pulls moisture into the upper layers of skin to keep the surface soft and hydrated.
It's worth knowing sugars are already a natural component of the skin's NMF (natural moisturizing factor) so it's a molecule that your stratum corneum is well-acquainted with.
Just so you know, glucose is hydrophilic (water-loving) and the stratum corneum is a strong barrier to hydrophilic compounds. This just means penetration is slow and most of the action is happening on the surface.
Gram-to-gram, glucose is not as efficient as a humectant as glycerin. This is why you'll likely see glycose paired with stronger humectants for a bigger hydration payoff.
In skincare, glucose is typically derived from corn or other starch sources.
Learn more about GlucoseLactic Acid is another well-loved alpha hydroxy acid (AHA). It is gentler than glycolic acid but still highly effective.
Its main role is to exfoliate the surface of the skin by loosening the “glue” that holds dead skin cells together. Shedding those old cells leads to smoother, softer, and more even-toned skin.
Because lactic acid molecules are larger than glycolic acid, they don’t penetrate as deeply. This means they’re less likely to sting or irritate, making it a great choice for beginners or those with sensitive skin.
Like glycolic acid, it can:
Lactic acid also acts as a humectant (like hyaluronic acid). It can draw water into the skin to improve hydration and also plays a role in the skin's natural moisturizing factor (NMF) in the form of sodium lactate.
Studies show it can boost ceramide production to strengthen the skin barrier and even help balance the skin’s microbiome.
To get results, choose products with a pH between 3-4.
Lower strengths (5-12%) focus on surface exfoliation; higher strengths (12% and up) can reach deeper in the dermis (deeper, supportive layer) to improve skin texture and firmness over time.
Though it was originally derived from milk, most modern lactic acid used in skincare is vegan. It is made through non-dairy fermentation to create a bio-identical and stable form suitable for all formulations.
When lactic acid shows up near the end of an ingredient list, it usually means the brand added just a tiny amount to adjust the product’s pH.
Legend has it that Cleopatra used to bathe in sour milk to help reduce wrinkles.
Lactic acid is truly a gentle multitasker: it exfoliates, hydrates, strengthens, and brightens. It's a great ingredient for giving your skin a smooth, glowing, and healthy look without the harshness of stronger acids.
Read more about some other popular AHA's here:
Learn more about Lactic AcidAlpha-Glucan Oligosaccharide is a prebiotic. It prevents harmful bacteria from growing on skin by keeping the skin's microbiome in balance.
Another benefit of this ingredient is its antioxidant properties. Antioxidants protect our skin from oxidative damage.
This ingredient is also called ethanol or ethyl alcohol. It is denatured, meaning made undrinkable for cosmetic use.
In formulas, it:
Is it bad for your skin?
The answer comes down to concentration. Patch and wash studies have found highly concentrated alcohol-based hand rubs (60-100%) cause less barrier disruption than washing with a basic detergent like SLS. The only measurable effect in these studies was a temporary dip in skin hydration.
Concentrations below 12-15% in leave-on cosmetics is generally well-tolerated. Concentrations above start to see increased transepidermal water loss (TEWL) and reduced hydration.
In concentrations about 58%, it creates temporary channels in your skin's lipid layers to become more permeable and allow other ingredients to slip through easily.
This ingredient can be up to 80% of the formula in alcohol-based perfumes.
Overall, this ingredient is probably harmless if found lower down an ingredients list but worth side-eyeing if it's high up (especially if your barrier is already struggling).
Alcohol can worsen dry skin, eczema, and oily skin, especially at higher concentrations. This is because it can increase transepidermal water loss and decrease hydration to disrupt the skin barrier.
According to the National Rosacea Society based in the US, you should be mindful of products with these alcohols in the top half of ingredients.
True allergic contact dermatitis to ethanol is uncommon, but be sure to patch test if you have dry or sensitive skin.
Learn more about Alcohol4-Terpineol is the main component of tea tree oil.
This ingredient is the reason tea tree oil has most of its reputation. Research points to a broad range of biological activity including antimicrobial, antioxidant, and anti-inflammatory effects.
Studies show it can significantly block the pathway involved in skin inflammation. It has also been shown to work against acne-causing bacteria, fungi, and even some viruses (and seems to be more effective on its own rather than part of tea tree oil).
Overall, this botanical extract is well-researched and skin-friendly.
Learn more about 4-TerpineolLecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids.
Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker:
It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers.
Learn more about LecithinIodopropynyl Butylcarbamate (IPBC) is a preservative that is especially good at getting fungi and mold out of your cosmetics.
IPBC works by leveraging the antimicrobial properties of its iodine containing structure. Iodine has been used as a germicide since the late 1800s and IPBC is a more refined and stable derivative of it.
It is typically used at very low levels in cosmetics, with most formulations using 0.0125% or less (well below its approved maximum).
In the EU, IPBC concentration limits are set at 0.02% in rinse-off products and 0.01% in leave-on products.
Though IPBC is a relatively uncommon contact allergen, patch testing studies show positive reaction rates ranging from 0.3%-0.9% of patients tested. This is still quite low compared to preservatives like methylisothiazolinone which sits at around 4-5%.
Researchers note that existing iodine sensitives or rubber allergies may be the cause of this as IPBC shares a structure with both thiuram (used in rubber) and iodine.
Be sure to patch test if you are unsure and speak with a medical professional about using this ingredient.
Learn more about Iodopropynyl ButylcarbamateWe don't have a description for Laminaria Saccharina Extract yet.
Arbutin is a naturally occurring molecule (found in bearberry, cranberry, and blueberry) that is used in skincare as a gentle brightening agent to fade dark spots, melasma, and post-inflammatory hyperpigmentation.
Chemically, it is a sugar-bound form of hydroquinone.
It works mainly by inhibiting tyrosinase, the enzyme your skin uses to make melanin. This means less new pigment gets produced over time.
There are two forms you'll see on labels: beta-arbutin (listed as just "Arbutin") and alpha-arbutin (the more stable and effective of the two).
The evidence behind this is solid: it's less cytotoxic to melanocytes than hydroquinone and comparably effective with kojic acid for hyperpigmentation.
One human study using a 10% solution reduced UVR-induced hyperpigmentation by 43.5% (jumping to 63.3% when paired with aloesin).
More recent clinical work backs it up too; a 2025 study on a 5% alpha-arbutin + 2% kojic acid cream found it comparable to triple combination prescription formulas but with lower recurrence for melasma.
Typical usage in cosmetics serums land in the 1-2% range.
It's a well-tolerated, non-irritating, and non-photoreactive ingredient that also gives some antioxidant benefits too.
Learn more about ArbutinBisabolol is a gentle skin conditioner, antioxidant, and soothing ingredient.
It's primary claim to fame is soothing and research shows topically applied bisabolol can quiet the chemical messengers that cause your skin to become inflamed, helping to sooth any irritation.
A clinical study found that applying 0.5% bisabolol daily for 8 weeks produced an average 9% decrease in skin pigmentation. Researchers found it can also suppress the process that leads to excess melanin production in skin.
In vitro studies found that bisabolol combined with propylene glycol significantly increased skin permeability by increasing lipid fluidity in the stratum corneum.
You'll likely see use concentrations quite low, usually 0.1-0.2%.
Overall, this is a well-tolerated ingredient that works well in formulas designed for sensitive, reactive, or post-procedure skin.
Learn more about BisabololTocopheryl Acetate is a stable, shelf-friendly form of vitamin E.
Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.
It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.
One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.
Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.
Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.
The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.
Most leave-on skincare keeps it at the lower end, often between 0.5-1%.
Learn more about Tocopheryl AcetateGlutathione is a tiny protein-like molecule (a "tripeptide" build from 3 amino acids: glycine, cysteine, and glutamic acid) that your body already makes on its own.
Inside your body, it acts as one of the skin's main antioxidants that help fight against free radicals.
In skincare, it's best known as a brightening ingredient that slows down tyrosinase, the key enzyme that makes skin pigment. It also nudges the skin toward making a lighter type of pigment instead of a darker one.
This is why you'll see it in products aimed at dark spots and uneven tone.
A small number of real human trials have found a topical glutathione lotion:
The honest caveat is that the current evidence is still thin (few studies, small groups, short timelines). Glutathione also doesn't absorb into skin very easily so results tend to be modest and fade if you stop using it.
One thing worth clearing up:
The scary side effects you may have heard about come from glutathione injected intravenously, which has real safety concerns. Applying it topically is a completely different thing and has a clean track record.
Most human studies used it around 2% (as Glutathione or Glutathione Disulfide) and a 2% oxidized glutathione lotion and a 2% S-acyl glutathione cream are the concentrations with actual clinical data behind them.
There's no established "ideal" percentage yet but 1-2% is the evidence-backed range.
Allergy-wise, there is very low risk for this ingredient; it was well-tolerated across the topical trials. Only one participant had mild temporary redness that cleared up on its own and another study reported no adverse reactions at all.
One trial had ~10% of users drop out for irritation was using a combination cream that also had 10% azelaic acid so the irritation likely wasn't from the glutathione. There's no notable contact-allergy signal for topical glutathione in the literature but patch-testing before first use is still sensible for those with sensitive skin.
Learn more about GlutathioneLinolenic Acid is also known as "ALA" or alpha-linolenic acid. It is a key fatty acid.
Our skin uses this ingredient for maintaining a healthy skin barrier, regulating inflammation, and supporting keratinocyte function.
ALA is a great skin hydrator because it has the ability to restore lipids in our stratum corneum, or outermost layer of our skin; it also helps prevent transepidermal water loss.
This ingredient also helps soothe irritated skin by downregulating inflammation.
Chia seed oil is one of the highest natural sources of ALA. Research shows topical chia seed oil significantly improves skin hydration, reduces itch, and strengthens the barrier in both healthy and extremely dry skin.
Additionally, in-vivo and in-vitro studies show ALA exhibits antioxidant properties, reduces UV-induced inflammation, and supports wound healing.
Early research showed a fatty-acid deficiency in animals leads to abnormal skin barrier function. It is believed a deficiency in linolenic acid may be linked to skin disorders like eczema.
Fun fact: This ingredient is considered an essential fatty acid for humans. This means our bodies cannot naturally produce it and we must get it from food. Some foods rich in linolenic acid include walnuts, fish oils, soy, and canola.
Learn more about Linolenic AcidLinoleic Acid is also known as Vitamin F. It is a fatty acid with emollient and skin conditioning properties.
Our top layer of skin, or epidermis, naturally contains high amounts of linoleic acid.
Your body uses linoleic acid to build ceramides and prostaglandins. Ceramides keep your skin's barrier hydrated and strong while prosaglandins help control inflammation and healing.
Needless to say, linoleic acid is crucial for having a strong skin barrier.
One study found applying linoleic acid rich sunflower oil to be more effective at repairing the skin barrier than olive oil.
This ingredient can also help treat acne by softening sebum to prevent clogged pores. Another study found using 2.5% linoleic acid gel for 4 weeks showed a 25% reduction in small comedones.
Studies show it can also help lighten hyperpigmentation or sun spots by disrupting the melanin production process. It also helps your skin shed melanin pigment from your skin caused by UV exposure.
Due to its role in the production of the fatty acid prostaglandin, linoleic acid can also help reduce inflammation and support wound healing.
Fun fact: Linoleic acid is an essential fatty acid. This means our bodies cannot create it on its own and we need to get it through foods such as nuts and vegetable oils.
Just know this ingredient is not always fungal-acne safe because it is a long-chain fatty acid (with 18 carbon atoms) that directly feeds the Malassezia yeast responsible for fungal acne.
Learn more about Linoleic AcidAscorbyl Palmitate is a fat-soluble form of vitamin C (Ascorbic Acid) made by combining it with palmitic acid.
It is able to blend easily into creams and oil-based formulas because it dissolves in oils rather than water.
As you may know, regular vitamin C is notorious for breaking down when exposed to sunlight and air. Ascorbyl Palmitate is more stable and degrades at a slower rate.
Research on whether it converts efficiently into active vitamin C once it's applied on your skin is still limited.
Some in-vitro studies suggest it may support collagen production, but it is not considered one of the stronger vitamin C derivatives, like:
Due to the palmitic acid base, this ingredient may not be fungal acne safe. Comedogenic studies have also shown this ingredient to have a rating of 2.
It's also worth keeping in mind that comedogenic and irritancy ratings are tested on individual ingredients, not finished formulas. The final product's formulation, concentration, and other ingredients all play a role in how something actually behaves on your skin.
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Read more about us· Updated May 17, 2025 • Added by masturahnorhizat