MDAIRE RXR Retinol Anti-Aging Serum
A serum with 38 ingredients, including AHA, retinoid, and niacinamide.
Overview
What it is
Serum with 38 ingredients that contains AHA, exfoliants, hyaluronic acid, niacinamide, peptides and retinoid
Cool Features
It is reef safe
Suited For
It has ingredients that are good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
It doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates
Fun facts
MDAIRE is from United States. This product is used in 6 routines created by our community.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside
Ingredients List
Water
Skin ConditioningSqualane
EmollientC12-15 Alkyl Benzoate
AntimicrobialPropanediol
SolventSodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingGlycerin
HumectantRetinol
Skin ConditioningGlycine Soja Hull
AbrasiveGlyceryl Stearate
EmollientPEG-100 Stearate
Niacinamide
SmoothingLactic Acid
BufferingArnica Montana Extract
Skin ConditioningHyaluronic Acid
HumectantResveratrol
AntioxidantKojic Acid
AntioxidantUbiquinone
AntioxidantPhenoxyethanol
PreservativeNannochloropsis Oculata Extract
HumectantPullulan
Palmitoyl Tripeptide-5
Skin ConditioningCellulose Gum
Emulsion StabilisingAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingChitosan
Glycolic Acid
BufferingPolysorbate 20
EmulsifyingSorbitan Oleate
EmulsifyingBHT
AntioxidantC15-19 Alkane
SolventPolyglyceryl-6 Laurate
EmulsifyingPolyglycerin-6
HumectantEthylhexylglycerin
Skin ConditioningHydrolyzed Collagen
EmollientPolypodium Leucotomos Leaf Extract
Skin ProtectingMelatonin
AntioxidantSodium Benzoate
MaskingPotassium Sorbate
PreservativeCaprylyl Glycol
EmollientWater, Squalane, C12-15 Alkyl Benzoate, Propanediol, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Glycerin, Retinol, Glycine Soja Hull, Glyceryl Stearate, PEG-100 Stearate, Niacinamide, Lactic Acid, Arnica Montana Extract, Hyaluronic Acid, Resveratrol, Kojic Acid, Ubiquinone, Phenoxyethanol, Nannochloropsis Oculata Extract, Pullulan, Palmitoyl Tripeptide-5, Cellulose Gum, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Chitosan, Glycolic Acid, Polysorbate 20, Sorbitan Oleate, BHT, C15-19 Alkane, Polyglyceryl-6 Laurate, Polyglycerin-6, Ethylhexylglycerin, Hydrolyzed Collagen, Polypodium Leucotomos Leaf Extract, Melatonin, Sodium Benzoate, Potassium Sorbate, Caprylyl Glycol
Key Ingredients
Benefits
Concerns
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterSqualane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.
Because squalane boosts hydration in the skin, it also comes with plenty of benefits: it is an antioxidant and can help fight free radicals and skin damage. Squalane is also found to have a detoxifying effect when applied.
Squalane comes from squalene, which occurs naturally within the sebum of our skin. It is one of the oils our skin produces to keep itself hydrated. Squalane is the hydrogenated version of squalene and has a longer shelf life.
Research shows that squalane is non-irritating (even at 100% concentration).
In general, it's a fantastic ingredient. It does a great job at hydrating the skin, and it's suitable for those with sensitive skin.
The source of squalane may impact malassezia / fungal acne. This is because olive oil derived squalane can contain impurities such as fatty acids and plant waxes. Sugarcane derived squalane is recommended for anyone with malassezia concerns.
Is squalane vegan?
This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.
Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.
Read more about squalene with an "e".
Is squalane an oil?
Squalane is often called an oil, but itโs technically not; itโs a hydrocarbon, meaning itโs only made of carbon and hydrogen, unlike true oils which are triglycerides made of fatty acids and glycerol.
The term โoil-freeโ isnโt regulated, so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.
While some people avoid oils thinking they cause breakouts, the right kind of oil (or oil-like ingredient like squalane) can actually help balance and hydrate your skin. Itโs worth testing out simple oils or squalane to see what works best for your skin.
Learn more about SqualaneC12-15 Alkyl Benzoate is made up of Benzoic Acid and long chain alcohols. It has a low molecular weight.
C12-15 Alkyl Benzoate is an emollient and texture enhancer. Due to its solubility, it is often used in sunscreens to help evenly distribute active ingredients.
As an emollient, C12-15 Alkyl Benzoate helps soften and hydrate your skin. Emollients create a film on your skin that traps moisture within.
This ingredient has been reported to cause eye irritation.
Learn more about C12-15 Alkyl BenzoatePropanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.ย
Itโs often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Learn more about PropanediolThis long ingredient is a copolymer of sodium acrylate and sodium acryloyldimethyl taurate monomers.
It is used to help stabilize other ingredients and create a thicker gel-like texture.
Emulsifiers prevent oils and waters from separating.
Learn more about Sodium Acrylate/Sodium Acryloyldimethyl Taurate CopolymerGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinRetinol is a gold-standard ingredient for anti-aging. It is a form of Vitamin A and belongs to the class of retinoids that also includes tretinoin.
Why is retinol famous?
It has the most scientific studies backing up its skin benefits out of all the non-prescription ingredients.
Retinol is proven to:
This is why retinol is effective at removing wrinkles, fading dark spots, treating acne, and reducing the appearance of pores.
Studies show retinol is less effective when exposed to UV. Be sure to look for appropriate packaging to keep your retinol potent (similar to Vitamin C).
Using retinol or any retinoids will increase sun-sensitivity in the first few months. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.
We recommend speaking with a medical professional about using this ingredient during pregnancy.
Retinol may cause irritation in some people, so be sure to patch test. Experts recommend 'ramping up' retinol use: start using this ingredient once a week and work up to using it daily.
Read about Tretinoin
Learn more about RetinolGlycine Soja Hull is an exfoliant.
Glyceryl Stearate is a mix of glycerin and stearic acid.
It is used to stabilize the mixing of water and oil ingredients. By preventing these ingredients from separating, it can help elongate shelf life. It can also help thicken the product's texture.
As an emollient, it helps soften skin and supports barrier-replenishing ingredients.
In cosmetics, Glyceryl Stearate is often made from vegetable oils or synthetically produced.
This ingredient may not be fungal-acne safe
Fun fact: The human body also creates Glyceryl Stearate naturally.
Learn more about Glyceryl StearatePeg-100 Stearate is an emollient and emulsifier. As an emollient, it helps keep skin soft by trapping moisture in. On the other hand, emulsifiers help prevent oil and water from separating in a product.
PEGS are a hydrophilic polyether compound . There are 100 ethylene oxide monomers in Peg-100 Stearate. Peg-100 Stearate is polyethylene glycol ester of stearic acid.
Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Learn more about NiacinamideLactic Acid is an AHA that is derived from fermenting lactose, a carbohydrate from milk. It removes the top layer of old and dead skin cells and helps increase cell turnover.
Benefits of Lactic Acid are that it can help to reduce large pores and reduce the effects of aging. Some potential downsides are that it can be bad for dry skin, cause irritation, worsen eczema, and worsen rosacea.
Not only does it help exfoliate the skin, it helps strengthen the skin's barrier. When applied, lactic acid helps the skin create ceramides.
Lactic acid is an over-the-counter chemical exfoliant that comes from the fermentation of lactose โ a carbohydrate found in milk.
Legend has it that Cleopatra used to bathe in sour milk to help reduce wrinkles.
Read more about some other popular AHA's here:
Learn more about Lactic AcidArnica Montana is more commonly known as Wolf's Bane.
The FDA considers Wolf's Bane to be an unsafe herb. They advise against taking it orally or applying it to broken skin.
Wolf's Bane has been said to have anti-inflammatory properties. However, studies are conflicting about whether this is true.
Learn more about Arnica Montana ExtractHyaluronic acid is naturally found in healthy skin. It is a humectant, meaning it draws moisture to your skin.
This ingredient helps hydrate, soothe, and protect the skin.
What makes hyaluronic acid so hydrating? It has the capacity to bind or hold large amounts of water.
Fun fact: It is already naturally found in our bodies, such as the fluids of our eyes and our joints.
Studies find this ingredient to have anti-inflammatory and anti-microbial properties. This can help speed up wound-healing.
Hyaluronic acid can be irritating if the molecule has a low-molecular weight, or if the molecules are small.
One study found low-molecular weight hyaluronic acid to be pro-inflammatory, meaning some people may experience irritation. This is because our bodies use hyaluronic acid in the wound-healing process to signal to our bodies, via irritation, that something needs healing.
The same study found high-molecular weight hyaluronic acid to be anti-inflammatory.
These are some other common types of Hyaluronic Acid:
Learn more about Hyaluronic AcidResveratrol is a famous emerging antioxidant. It is a good alternative for sensitive skin types who cannot tolerate retinoids.
This antioxidant is most famous for it's anti-aging benefits. Studies show it combats the signs of aging by:
Besides anti-aging, this ingredient also helps with skin brightening and soothing.
The most effective forms of resveratrol are isobutyrate and butyrate. These have the strongest effect on increasing A1 collagen and reducing inflammation.
A note on it being a retinoid alternative:
Despite it's amazing skin benefits, it is not a replacement for retinoids. However, it is recommended for people with sensitive skin or intolerance to retinoids.
Resveratrol is naturally found in grapes, peanuts, and berries.
Learn more about ResveratrolKojic acid comes from fungi and can also be from fermented foods. It helps even out skin tone and reduce hyperpigmentation.
This ingredient works by blocking tyrosine, an enzyme that starts the process of skin darkening.
Kojic Acid is antifungal and often used to treat fungal infections. Additionally, it can help fight bacteria with its antimicrobrial properties. This can help treat acne as well.
A similar ingredient is arbutin.
Learn more about Kojic AcidUbiquinone (Coenzyme Q10) is a molecule already found in our bodies. It is a potent antioxidant and skin-soothing ingredient.
Aging and environmental exposure diminishes our skin's natural ubiquinone levels. This is much like our natural collagen and elastin.
The good news is: studies show applying this ingredient topically replenishes ubiquinone levels in our skin. This also comes with a ton of skin benefits. These benefits include:
Ubiquinone is considered a large molecule and cannot be absorbed into the lower layers of skin. This is why it is believed to be such an effective antioxidant: it protects our skin in the upper layers and prevents damage in the deeper layers.
When used in sunscreen, ubiquinone is shown to increase ingredient stability, increase SPF factor, and add to infrared protection.
Fun fact: ubiquinone is fat-soluble.
Learn more about UbiquinonePhenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
We don't have a description for Nannochloropsis Oculata Extract yet.
Pullulan is a low viscosity polysaccharide (a long chain carbohydrate) with binding and film forming properties when dissolved in water. It is used to create a "silicone-like" or silky feel in cosmetics without adding viscosity.
According to a manufacturer, this ingredient's ability to easily dissolves makes it a great carrier for active ingredients.
Due to it being edible and tasteless, you'll likely find this ingredient in breath freshener strips. This ingredient is produced from the starch of the fungus, Aureobasidium pullulans.
Pullulan is stable over a broad-range of pH.
Learn more about PullulanThis synthetic peptide is created from lysine, valine, and palmitic acid.
According to the manufacturer, in-vitro studies show tissue growth and collagen synthesis. Another in-vivo study found 60 volunteers saw a significant reduction in wrinkles after 84 days.
Due to its palmitic acid base, this peptide may not be fungal-acne safe.
Learn more about Palmitoyl Tripeptide-5Cellulose Gum is a water-soluble polymer that comes from cellulose. It is used to change the texture of a product and to help stabilize emulsions.
As an emulsifier, cellulose gum specifically thicken the texture of water-based products.
This ingredient is considered hypoallergenic and non-toxic. Cellulose Gum can be found in cosmetics, food, and other household goods such as paper products.
Learn more about Cellulose GumAcrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken and improve the texture of products. Due to its properties, it can prevent water and oil ingredients from separating.
We don't have a description for Chitosan yet.
Glycolic Acid is arguably the most famous AHA with a ton of research to back up its benefits.
Its main role is to remove the top layer of dead skin cells, allowing newer skin cells to emerge.
Specifically, AHAs work by breaking down the structural "glue" holding the old skin cells in place. Getting rid of the old skin cells allows skin to regenerate newer skin cells in its place. A build up of dead skin cells can lead to tired and dull looking skin.
Due to this, glycolic acid helps with:
Fun fact: Glycolic acid increases skin hydration by playing a role in creating molecules that create hyaluronic acid naturally.
When starting glycolic Acid, it is normal to feel slight stinging.
The pH value and concentration of glycolic acid play a role in the effectiveness of the product. Concentrations between 5-20% glycolic acid have been shown to be effective in clinical studies.
Recent studies have shown Glycolic Acid may protect the skin against UV damage. However, you should always wear SPF, especially when using exfoliants.
Read more about some other popular AHA's here:
Learn more about Glycolic AcidPolysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.
As a surfactant, it helps collect dirt and oils for washing. Emulsifiers prevent oils and water from separating.
Polysorbate 20 also adds scent to a product. Since it is made using sorbitol, it has a sweet scent. Sorbitol can also be found in fruits such as apples and peaches.
The lauric acid used to create Polysorbate 20 is often derived from coconuts.
Polysorbate 20 may not be fungal acne safe.
Learn more about Polysorbate 20Sorbitan Oleate is created from compounds in oleic acid and sorbitol.
It is used to stabilize a product by preventing ingredients from separating. Emulsifiers help keep ingredients together, such as oils and water.
According to a manufacturer, the ingredient Sorbitan Monooleate shares an INCI name with this one.
Sorbitan Oleate may not be fungal acne safe. It can also worsen oily skin.
Learn more about Sorbitan OleateBHT is a synthetic antioxidant and preservative.
As an antioxidant, it helps your body fight off free-radicals. Free-radicals are molecules that may damage your skin cells.
As a preservative, it is used to stabilize products and prevent them from degrading. Specifically, BHT prevents degradation from oxidation.
The concerns related to BHT come from oral studies; this ingredient is currently allowed for use by both the FDA and EU.
However, it was recently restricted for use in the UK as of April 2024.
Learn more about BHTC15-19 alkane is a mixture of alkanes. Alkanes are hydrocarbons with carbon atoms held together by single bonds.
It is a synthetically created solvent and emollient often used to replace silicones or mineral oil. As an emollient, C15-19 Alkane helps soften and soothe the skin. Emollients create a barrier to trap moisture inside.
C15-19 Alkane is often used with mineral UV filters such as titanium dioxidide and zinc oxide. It helps these UV filter ingredients be more spreadable.
C15-19 Alkane is biodegradable.
Learn more about C15-19 AlkanePolyglyceryl-6 Laurate isn't fungal acne safe.
We don't have a description for Polyglycerin-6 yet.
Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.
Hydrolyzed collagen has a misleading name because it is actually a mixture of various proteins/peptides. This ingredient has skin hydrating properties.
Collagen is the most abundant type of structural protein found in your body. In your skin, it is responsible for keeping it firm and youthful.
Hydrolyzed Collagen is created by breaking up proteins into smaller peptide bonds. These peptides act as humectants and emollients.
Humectants are great at holding onto water, keeping skin hydrated. Emollients create a thin barrier on the skin to prevent moisture from escaping.
There is ongoing debate about whether hydrolyzed collagen works because it increases skin hydration. Skin hydration is also linked to elasticity and the appearance of wrinkles.
Collagen or peptide ingredients can be used in the morning or night. They will not increase sun sensitivity, but you should always wear sunscreen during the day.
According to a manufacturer, this ingredient is a great hair conditioner as well.
This ingredient can be extracted from different sources, including:
Vegan collagen is derived from yeast, bacteria, or plant sources. Vegan collagen would go by a different INCI name, such as hydrolyzed soy protein.
The results are varied.
A study from 2021 found hydrolyzed collagen increased elasticity and improved wrinkles in 1,125 participants between age 20 and 70. Another study found increased skin thickness in participants between the ages of 45 to 59.
However, It is difficult to prove that oral collagen will end up working on your skin. Many of the studies using hydrolyzed collagen also add several vitamins and nutrients into the test mixture as well.
Further studies are needed at this time.
Learn more about Hydrolyzed CollagenWe don't have a description for Polypodium Leucotomos Leaf Extract yet.
Melatonin is an antioxidant.
Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.
Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.
Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.
It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.
Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.
We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.
Learn more about Sodium BenzoatePotassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.
This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.
Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.
You'll often find this ingredient used with other preservatives.
Learn more about Potassium SorbateCaprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.
It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.
Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.
This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.
Learn more about Caprylyl GlycolReviews
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Where it's from
MDAIRE is a American brand
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about usยท Updated October 2, 2025 • Added by edenbeutler