Madeca Derma Elastic Firming Microbiome Ampoule
A cruelty-free ampoule that contains aha, hyaluronic acid, niacinamide and peptides.
Overview
What it is
Ampoule with 37 ingredients that contains AHA, hyaluronic acid, niacinamide and peptides
Cool Features
It is cruelty-free and reef safe
Suited For
It has ingredients that are good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
It doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens or silicones
Fun facts
Madeca Derma is from South Korea.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
About this product
Ingredients List
Dive into the full list of ingredients.
Water
Skin ConditioningPentylene Glycol
Skin ConditioningNiacinamide
SmoothingGlycerin
HumectantMethylpropanediol
SolventSodium PCA
HumectantButylene Glycol
HumectantPanthenol
Skin ConditioningSodium Hyaluronate
HumectantBeta-Glucan
Skin ConditioningAdenosine
Skin ConditioningSodium Citrate
BufferingFructooligosaccharides
HumectantFructose
HumectantChlorella Vulgaris Extract
Skin ConditioningCitric Acid
BufferingGlucose
HumectantGlycine Soja Seed Extract
Skin ConditioningDextrin
AbsorbentMannose
HumectantRibose
Humectant1,2-Hexanediol
Skin ConditioningOctanediol
Ethylhexylglycerin
Skin ConditioningCollagen
MoisturisingHydrolyzed Collagen
EmollientHedera Helix Extract
AntimicrobialSorbitan Laurate
EmulsifyingHydroxyethylcellulose
Emulsion StabilisingAcetyl Dipeptide-1 Cetyl Ester
Skin ConditioningPalmitoyl Tripeptide-5
Skin ConditioningCaprylyl Glycol
EmollientAcetyl Hexapeptide-8
HumectantHexapeptide-9
Skin ConditioningNonapeptide-1
Skin ConditioningCalcium Chloride
AstringentMagnesium Sulfate
Water, Pentylene Glycol, Niacinamide, Glycerin, Methylpropanediol, Sodium PCA, Butylene Glycol, Panthenol, Sodium Hyaluronate, Beta-Glucan, Adenosine, Sodium Citrate, Fructooligosaccharides, Fructose, Chlorella Vulgaris Extract, Citric Acid, Glucose, Glycine Soja Seed Extract, Dextrin, Mannose, Ribose, 1,2-Hexanediol, Octanediol, Ethylhexylglycerin, Collagen, Hydrolyzed Collagen, Hedera Helix Extract, Sorbitan Laurate, Hydroxyethylcellulose, Acetyl Dipeptide-1 Cetyl Ester, Palmitoyl Tripeptide-5, Caprylyl Glycol, Acetyl Hexapeptide-8, Hexapeptide-9, Nonapeptide-1, Calcium Chloride, Magnesium Sulfate
Key Ingredients
Benefits
Concerns
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterPentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.
The hydrophilic trait of Pentylene Glycol makes it a humectant. As a humectant, Pentylene Glycol helps draw moisture from the air to your skin. This can help keep your skin hydrated.
This property also makes Pentylene Glycol a great texture enhancer. It can also help thicken or stabilize a product.
Pentylene Glycol also acts as a mild preservative and helps to keep a product microbe-free.
Some people may experience mild eye and skin irritation from Pentylene Glycol. We always recommend speaking with a professional about using this ingredient in your routine.
Pentylene Glycol has a low molecular weight and is part of the 1,2-glycol family.
Learn more about Pentylene GlycolNiacinamide has emerged as an all-star ingredient due to its many benefits.
It is known to treat acne by reducing inflammation. It also helps fade dark-spots and strengthen the skin by promoting the growth of the ceramide barrier.
Other benefits include smoothing wrinkles and minimizing redness.
The cherry on top? Niacinamide can also help build keratin, a protein that keeps skin firm.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
Niacinamide can be mixed with other ingredients to boost benefits. For instance, it has shown to be effective when used with copper, folic acid, and zinc to treat acne.
Learn more about NiacinamideGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinMethylpropanediol is a synthetic solvent and humectant.
As a solvent, it helps dissolve other ingredients, helping to evenly distribute ingredients throughout the product. This ingredient has also been shown to have antimicrobial properties which makes it a preservative booster.
Methylpropanediol is able to add a bit of moisture to the skin. It also helps other ingredients be better absorbed into the skin, such as salicylic acid.
Learn more about MethylpropanediolSodium PCA is the sodium salt of pyroglutamic acid. It is naturally occurring in our skin's natural moisturizing factors where it works to maintain hydration.
The PCA stands for pyrrolidone carboxylic acid, a natural amino acid derivative.
This ingredient has skin conditioning, anti-inflammatory, and humectant properties. Humectants help hydrate your skin by drawing moisture from the air. This helps keep your skin moisturized.
Learn more about Sodium PCAButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
- It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
- It is a humectant, which means that it helps attract moisture into the skin.
- It helps improve product application.
- It has mild preservative properties.
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Learn more about PanthenolSodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.
Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.
Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.
These are some other common types of Hyaluronic Acid:
Learn more about Sodium HyaluronateBeta-Glucan is a polysaccharide. It can be derived from the cell walls of seaweed, oats, yeast, and fungi. It hydrates the skin and helps boost your skin's natural barrier.
As an antioxidant, beta-glucan helps fight free-radicals. Free-radicals are molecules that may damage your skin cells, such as pollution.
Studies show this ingredient may be an effective wrinkle reducer as it can deeply penetrate into skin. It has also been show to help with wound healing.
Learn more about Beta-GlucanAdenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.
Adenosine has many benefits when used. These benefits include hydrating the skin, smoothing skin, and reducing wrinkles. Once applied, adenosine increases collagen production. It also helps with improving firmness and tissue repair.
Studies have found adenosine may also help with wound healing.
In skincare products, Adenosine is usually derived from yeast.
Learn more about AdenosineSodium Citrate is the sodium salts of citric acid. In skincare, it is used to alter pH levels and acts as a preservative.
Its main functions are to maintain the pH of a product and neutralize metal ions.
The acidity of our skin is maintained by our glands and skin biome; normal pH level of skin is slightly acidic (~4.75-5.5).
Being slightly acidic allows our skin to create an "acid mantle". This acid mantle is a thin barrier that protects our skin from bacteria and contaminants.
Learn more about Sodium CitrateFructooligosaccharides is an alternative sweetener. It is often derived from the blue agave plant.
This ingredient is a prebiotic and helps to hydrate the skin. Emerging studies are also showing fructooligosaccharides to have antioxidant properties.
As a humectant, Fructooligosaccharides helps draw moisture to the skin, helping to hydrate the skin.
Bananas, onions, garlic, asparagus, jícama, and leeks also contain fructooligosaccharides.
Learn more about FructooligosaccharidesChlorella Vulgaris Extract comes from a green microalga. It is hydrating and contains antioxidants.
Studies also show Chlorella Vulgaris may help in rebuilding collagen and elastin. This ingredient is made up of lipids, carbohydrates, and chlorophyll.
Fun fact: This ingredient is commonly used as food additive in Japan.
Learn more about Chlorella Vulgaris ExtractCitric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).
As an AHA, Citric Acid removes the top layer of skin cells from the newer layer of skin underneath. This helps skin to remove dark spots and even out skin tone.
If you spot Citric Acid near the end of an ingredient list, it's likely there as a pH adjuster rather than an active ingredient.
Read more about some other popular AHA's here:
Learn more about Citric AcidGlucose is a simple sugar and is the most important source of energy in all organisms.
In skincare, glucose is used to hydrate the skin. It also acts as a prebiotic for our natural biome.
Glucose is hydrating due to its humectant property. As a humectant, glucose draws moisture from the air and from deeper levels in the skin.
Our skin contains many sugars that act as prebiotics and help strengthen our natural microbiome. Having a healthy microbiome helps protect our skin from harmful bacteria and other contaminants.
Studies show glucose may help with fading discoloration and pigmentation. This is because our skin metabolizes glucose into lactic acid. Lactic acid is an AHA that helps exfoliate the top layer of skin.
Learn more about GlucoseGlycine Soja Seed Extract comes from the seed of the wild soybean plant. Wild soybean extract contains fatty acids (linoleic, oleic, linolenic), vitamin E, and antioxidants.
The wild soybean contains soyasaponins, a bioactive compound. Soyasaponins have inflammatory, antimutagenic, anticarcinogenic, antimicrobial properties. Soyasaponin has also been found to inhibit the melanin-creation process.
Two powerful components found in the wild soybean include genistein and diadzein. These two isoflavones are potent antioxidants with anti-inflammatory properties. Genistein in particular has been found to prevent redness caused by UV exposure.
One study from South Korea found wild soybean extract to help promote hair growth at the cellular level.
The wild soybean plant is a cousin to the famous soybean that gives us tofu, soy milk, and soy sauce.
Learn more about Glycine Soja Seed ExtractDextrin is used to thicken a product and helps bind ingredients together. It is created from starch and glycogen.
As an emulsifier, dextrin prevents ingredients from separating. This helps elongate a product's shelf life.
Studies show coating UV filters with dextrin prevents these ingredients from being absorbed. This helps UV ingredients last longer on the skin.
Learn more about DextrinWe don't have a description for Mannose yet.
We don't have a description for Ribose yet.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
We don't have a description for Octanediol yet.
Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.
Collagen is the most abundant type of structural protein found in your body. It is an effective skin moisturizer.
There is no conclusive proof that collagen is used by skin when applied topically. However, it is a great humectant that hydrates skin. Hydrated skin is associated with increased elasticity and a decrease in the appearance of wrinkles. It is also essential for maintaining a healthy skin barrier.
Biologically, collagen is responsible for keeping skin firm and youthful. Collagen is comprised mostly of glycine, proline, and hydroxypoline. These are amino acids.
Collagen will not increase sun sensitivity, but you should always wear sunscreen during the day.
Learn more about hydrolyzed collagen here.
Learn more about CollagenHydrolyzed collagen has a misleading name because it is actually a mixture of various proteins/peptides. This ingredient has skin hydrating properties.
Collagen is the most abundant type of structural protein found in your body. In your skin, it is responsible for keeping it firm and youthful.
Hydrolyzed Collagen is created by breaking up proteins into smaller peptide bonds. These peptides act as humectants and emollients.
Humectants are great at holding onto water, keeping skin hydrated. Emollients create a thin barrier on the skin to prevent moisture from escaping.
There is ongoing debate about whether hydrolyzed collagen works because it increases skin hydration. Skin hydration is also linked to elasticity and the appearance of wrinkles.
Collagen or peptide ingredients can be used in the morning or night. They will not increase sun sensitivity, but you should always wear sunscreen during the day.
According to a manufacturer, this ingredient is a great hair conditioner as well.
This ingredient can be extracted from different sources, including:
Vegan collagen is derived from yeast, bacteria, or plant sources. Vegan collagen would go by a different INCI name, such as hydrolyzed soy protein.
The results are varied.
A study from 2021 found hydrolyzed collagen increased elasticity and improved wrinkles in 1,125 participants between age 20 and 70. Another study found increased skin thickness in participants between the ages of 45 to 59.
However, It is difficult to prove that oral collagen will end up working on your skin. Many of the studies using hydrolyzed collagen also add several vitamins and nutrients into the test mixture as well.
Further studies are needed at this time.
Learn more about Hydrolyzed CollagenWe don't have a description for Hedera Helix Extract yet.
Sorbitan Laurate is created from lauric acid and derivatives from sorbitol. It is an emulsifier.
Hydroxyethylcellulose is used to improve the texture of products. It is created from a chemical reaction involving ethylene oxide and alkali-cellulose. Cellulose is a sugar found in plant cell walls and help give plants structure.
This ingredient helps stabilize products by preventing ingredients from separating. It can also help thicken the texture of a product.
This ingredient can also be found in pill medicines to help our bodies digest other ingredients.
Learn more about HydroxyethylcelluloseAcetyl Dipeptide-1 Cetyl Ester is a peptide composed of amino acids arginine and tyrosine.
This peptide is considered a neurotransmitter peptide, meaning it has pain-relieving and relaxing properties. It has the ability to calm skin irritation from external factors such as chemical stinging or heat.
Neurotransmitter peptides are also often called "botox in a bottle". This is because these peptides have the ability to relax the muscles.
Though relaxing the muscles can prevent expression lines (as we have seen in botox), the studies do not show these peptides to be a botox replacement. The effects of this muscle relaxation is also short-term, as opposed to longer-term results from botox.
Learn more about Acetyl Dipeptide-1 Cetyl EsterThis synthetic peptide is created from lysine, valine, and palmitic acid.
According to the manufacturer, in-vitro studies show tissue growth and collagen synthesis. Another in-vivo study found 60 volunteers saw a significant reduction in wrinkles after 84 days.
Due to its palmitic acid base, this peptide may not be fungal-acne safe.
Learn more about Palmitoyl Tripeptide-5Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.
It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.
Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.
This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.
Learn more about Caprylyl GlycolAcetyl Hexapeptide-8 is a peptide. A common name for this peptide is Argireline.
Argireline has a similar function to botox; it prevents muscle movement and contractions slightly. By preventing muscles from moving, argireline also prohibits the formation of fine lines and wrinkles. However, research is lacking in proving this ingredient to be as effective as botox.
On the other hand, argireline tells our body to create more collagen. Collagen is a protein that makes connective tissue. Boosting collagen production leads to a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin.
Read more about other common types of peptides here:
Learn more about Acetyl Hexapeptide-8Hexapeptide-9 is a peptide.
Nonapeptide-1 is created from amino acids including arginine and lysine.
It has antioxidant and antimicrobial properties.
Emerging studies show Nonapeptide-1 to help with reducing pigmentation and brightening the skin. It has shown to prevent the activation of tyrosinase, an enzyme in the skin that begins the process of melanin creation. Melanin is responsible for giving skin a tan or dark spots.
Learn more about Nonapeptide-1We don't have a description for Calcium Chloride yet.
Magnesium Sulfate is a salt. It can be naturally found in sea water or mineral deposits.
In cosmetics, Magnesium Sulfate is used to thicken a product or help dilute other solids. It is a non-reactive and non-irritating ingredient.
You might recognize Magnesium Sulfate as epsom salt, or the bath salt used to help relieve muscle aches.
One study shows magnesium deficiency may lead to inflammation of the skin. Applying magnesium topically may help reduce inflammation.
Learn more about Magnesium SulfateReviews
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Where it's from
Madeca Derma is a Korean brand
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about us· Updated March 4, 2025 • Added by rebeccamccarty