Isov Time Reset HD Serum

Methylpropanediol is able to add a bit of moisture to the skin. It also helps other ingredients be better absorbed into the skin, such as salicylic acid.

Some foods that contain glyceryl glucoside include sake, miso, and wines.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this.

Studies show dimethyl isosorbide is able to penetrate skin to deliver other ingredients into the skin, making them more effective.

Other benefits include smoothing wrinkles and minimizing redness.

The cherry on top? Niacinamide can also help build keratin, a protein that keeps skin firm.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

Niacinamide can be mixed with other ingredients to boost benefits. For instance, it has shown to be effective when used with copper, folic acid, and zinc to treat acne.

Tocopheryl Acetate is commonly found in both skincare and dietary supplements.

Fun fact: Betaine is naturally created in the skin and body. The kind found within cosmetic products can be either plant-derived or synthetic.

While glutathione is said to help with fading dark spots, the results from research are inconclusive. Further studies are needed. With that said, gluthatione has been shown to protect our skin from UV-B induced damage.

This ingredient is naturally occurring in plants, animals, fungi, and some bacteria.

Due to its antioxidant properties, trehalose may help with signs of aging. Antioxidants help fight free-radical molecules, unstable molecules that may damage your skin.

In medicine, trehalose and hyaluronic acid are used to help treat dry eyes.

Some animals, plants, and bacteria create trehalose as a source of energy to survive freeze or lack of water.

Antioxidants help fight free-radical molecules. Free-radical molecules are capable of damaging our cells and other genetic material. Antioxidants help stabilize free-radicals by donating extra electrons. Grape seed extract may help reduce the signs of aging.

The antimicrobial properties of grape seed may help treat acne. However, more research is needed to support this claim.

Grape seed has also been found to help absorb UV rays. Grape seed extract should not replace your sunscreen.

Retinyl Propionate is an ester of retinol, like Retinyl Palmitate. Though the conversion line is longer for this ingredient - the results seem promising.

A study from 2021 found Retinyl Propionate to be just as effective as retinol . FYI - Retinol is one of the most well-studied OTC ingredients.

Other studies show promising results as well:

Reducing sun damage helps with: reducing the appearance of wrinkles, evening out skin tone, increasing skin plumpness, and decreasing dullness.

Using retinol or any retinoids will increase sun-sensitivity in the first few months. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.

Studies show the compounds in centella help with:

The combination of all these properties makes centella effective at soothing, hydrating, and protecting the skin.

Other great components of centella include Vitamin A, vitamin C, several B vitamins, and Asiatic Acid.

Fun fact: Centella has been used as a medicine and in food for many centuries. As a medicine, it is used to treat burns, scratches, and wounds.

Antioxidant components in chamomile make it an effective ingredient to help slow the signs of aging. Antioxidants help fight free-radical molecules, or molecules that may damage your skin.

Essential oils from chamomile have been found to improve wound healing due to its antimicrobial properties.

Ancient Greeks and Egyptians used Chamomile to treat skin redness and dryness. Chamomile has also been used to help treat stomach issues.

Retinoids have been proven to:

So what is the difference between all the retinoids? Most retinoids need to go through a conversion line to become effective on skin. The ending product is retinoic acid. Retinoic acid is AKA tretinoin.

HPR is an ester of tretinoin. Emerging studies suggest HPR to have an added benefit that other retinoids don't have: Low irritation.

A study from 2021 found HPR to have the greatest stability when exposed to light and temperature out of all the commercial retinoids.

A note about naming: The name "Granactive" is the trade name and the name most commonly used on packages.

Granactive is the name of the mixture - about 90% solvent and 10% HPR. A product with 5% granactive has 0.5% HPR.

Arginine isn't fungal acne safe when used in the presence of other lipids (fats, fatty acids, oils, esters, etc). Oils and fats occur naturally within the skin, so take caution when using Arginine if you're prone to fungal acne.

Ceramides are an important building block for our skin barrier. A stronger barrier helps the skin look more firm and hydrated. By bolstering the skin ceramides act as a barrier against irritating ingredients. This can help with inflammation as well.

If you would like to eat ceramides, sweet potatoes contain a small amount.

Read more about other common types of ceramides here: Ceramide AP Ceramide EOP

This ingredient can also be found in pill medicines to help our bodies digest other ingredients.

Besides anti-aging, this ingredient also helps with skin brightening and soothing.

The most effective forms of resveratrol are isobutyrate and butyrate. These have the strongest effect on increasing A1 collagen and reducing inflammation.

A note on it being a retinoid alternative: Despite it's amazing skin benefits, it is not a replacement for retinoids. However, it is recommended for people with sensitive skin or intolerance to retinoids.

Resveratrol is naturally found in grapes, peanuts, and berries.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Glucose is hydrating due to its humectant property. As a humectant, glucose draws moisture from the air and from deeper levels in the skin.

Our skin contains many sugars that act as prebiotics and help strengthen our natural microbiome. Having a healthy microbiome helps protect our skin from harmful bacteria and other contaminants.

Studies show glucose may help with fading discoloration and pigmentation. This is because our skin metabolizes glucose into lactic acid. Lactic acid is an AHA that helps exfoliate the top layer of skin.

Studies have found adenosine may also help with wound healing.

In skincare products, Adenosine is usually derived from yeast.

Curcumin also has anti-inflammatory properties and can help soothe skin and reduce irritation. On top of that, curcumin has been shown to help prevent hyperpigmentation from sun damage.

The anti-microbial property of turmeric can make it effective in treating acne. This property has also been shown to help regulate the production of sebum.