Dermwel Dermaboost Moisture Complex
A moisturizer with 47 ingredients, including vitamin E and peptides.
Overview
What it is
General moisturizer with 47 ingredients that contains peptides and Vitamin E
Cool Features
It is vegan, cruelty-free, and reef safe
Suited For
It has ingredients that are good for anti aging, dry skin, brightening skin, sensitive skin and scar healing
Free From
It doesn't contain any harsh alcohols, common allergens, oils, parabens, silicones or sulfates
Fun facts
Dermwel is from United States. This product is used in 4 routines created by our community.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside
Ingredients List
Water
Skin ConditioningGlycerin
HumectantPropanediol
SolventSqualane
EmollientCetyl Ethylhexanoate
EmollientAmmonium Acryloyldimethyltaurate/Vp Copolymer
Polyester-5
Superoxide Dismutase
AntioxidantUbiquinone
AntioxidantNicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-47
Skin ConditioningTripeptide-2
Skin ConditioningNonapeptide-1
Skin ConditioningAdenosine
Skin ConditioningBeta-Glucan
Skin ConditioningRibose
HumectantIlex Paraguariensis Leaf Extract
PerfumingCopper Lysinate/Prolinate
Skin ConditioningTocopheryl Acetate
AntioxidantSodium PCA
HumectantSodium Lactate
BufferingPCA
HumectantCaprylyl Glycol
EmollientPentylene Glycol
Skin Conditioning1,2-Hexanediol
Skin ConditioningCaprylhydroxamic Acid
Allantoin
Skin ConditioningGlycine
BufferingSerine
MaskingAlanine
MaskingValine
MaskingIsoleucine
Skin ConditioningProline
Skin ConditioningThreonine
Histidine
HumectantPhenylalanine
MaskingAspartic Acid
MaskingArginine
MaskingAcetamidoethoxyethanol
HumectantPolyglyceryl-3 Methylglucose Distearate
EmulsifyingGlyceryl Stearates
EmollientMethylglucoside Phosphate
Skin ConditioningXanthan Gum
EmulsifyingHydroxyacetophenone
AntioxidantUndecane
EmollientTridecane
PerfumingTetrasodium Glutamate Diacetate
Citric Acid
BufferingWater, Glycerin, Propanediol, Squalane, Cetyl Ethylhexanoate, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Polyester-5, Superoxide Dismutase, Ubiquinone, Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-47, Tripeptide-2, Nonapeptide-1, Adenosine, Beta-Glucan, Ribose, Ilex Paraguariensis Leaf Extract, Copper Lysinate/Prolinate, Tocopheryl Acetate, Sodium PCA, Sodium Lactate, PCA, Caprylyl Glycol, Pentylene Glycol, 1,2-Hexanediol, Caprylhydroxamic Acid, Allantoin, Glycine, Serine, Alanine, Valine, Isoleucine, Proline, Threonine, Histidine, Phenylalanine, Aspartic Acid, Arginine, Acetamidoethoxyethanol, Polyglyceryl-3 Methylglucose Distearate, Glyceryl Stearates, Methylglucoside Phosphate, Xanthan Gum, Hydroxyacetophenone, Undecane, Tridecane, Tetrasodium Glutamate Diacetate, Citric Acid
Key Ingredients
Benefits
Concerns
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinPropanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.ย
Itโs often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Learn more about PropanediolSqualane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).
It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.
This is due to how structurally similar it is to what your skin already produces.
Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.
Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.
No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).
Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.
This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.
Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.
Read more about squalene with an "e".
Though squalane is often called an oil, itโs technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.
The term โoil-freeโ isnโt regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.
Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.
A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.
The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.
Learn more about SqualaneCetyl Ethylhexanoate is an emollient ester. It comes from cetearyl alcohol and 2-ethylhexanoic acid.
Cetyl Ethylhexanoate is an emollient that adds a velvety feel to skin without being greasy or oily. Emollients help trap moisture into your skin, keeping your skin soft and hydrated.
Ammonium Acryloyldimethyltaurate/Vp Copolymer is a synthetically created polymer. It's used as a film-forming agent and used to thicken the consistency of products.
Think of it as a supportive ingredient that helps your gel-creams feel silky, "cloud cream-like", and spread evenly without being greasy.
The Cosmetic Ingredient Review (CIR) Expert Panel evaluated it (along with 22 other acryloyldimethyltaurate polymers) and concluded it's:
Due to its large molecular size, it sits on the surface of skin rather than penetrating it.
Learn more about Ammonium Acryloyldimethyltaurate/Vp CopolymerWe don't have a description for Polyester-5 yet.
Superoxide Dismutase is found in all living cells. This ingredient is AKA as 'SOD'.
SOD is a strong antioxidant. It protects living cells against oxidative damage by breaking down radical molecules into regular oxygen and hydrogen peroxide.
Antioxidants help fight free-radical molecules that may damage your skin's DNA. This may help with the signs of aging. Due to its antioxidant property, it is used to help treat chronic inflammation.
In cosmetics, SOD is usually obtained from marine phytoplankton, bovine liver, horseradish, cantaloupe, and certain bacteria.
The three major families of SOD include: Copper/Zinc, Iron/Manganese, and Nickel.
When eating SOD-rich foods, our bodies break it down into amino acids before absorption. Foods that contain SOD include: melons, citrus, spinach, broccoli, kale, almonds, sunflower seeds, and blue-green algae.
Learn more about Superoxide DismutaseUbiquinone (Coenzyme Q10) is a molecule already found in our bodies. It is a potent antioxidant and skin-soothing ingredient.
Aging and environmental exposure diminishes our skin's natural ubiquinone levels. This is much like our natural collagen and elastin.
The good news is: studies show applying this ingredient topically replenishes ubiquinone levels in our skin. This also comes with a ton of skin benefits. These benefits include:
Ubiquinone is considered a large molecule and cannot be absorbed into the lower layers of skin. This is why it is believed to be such an effective antioxidant: it protects our skin in the upper layers and prevents damage in the deeper layers.
When used in sunscreen, ubiquinone is shown to increase ingredient stability, increase SPF factor, and add to infrared protection.
Fun fact: ubiquinone is fat-soluble.
Learn more about UbiquinoneNicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-47 is a peptide.
Tripeptide-2 protects our collagen and elastin fibers to slow down the process of aging. It does this by inhibiting the proteins responsible for the breakdown of collagen and elastin.
Nonapeptide-1 is created from amino acids including arginine and lysine.
It has antioxidant and antimicrobial properties.
Emerging studies show Nonapeptide-1 to help with reducing pigmentation and brightening the skin. It has shown to prevent the activation of tyrosinase, an enzyme in the skin that begins the process of melanin creation. Melanin is responsible for giving skin a tan or dark spots.
Learn more about Nonapeptide-1Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.
Adenosine has many benefits when used. These benefits include hydrating the skin, smoothing skin, and reducing wrinkles. Once applied, adenosine increases collagen production. It also helps with improving firmness and tissue repair.
Studies have found adenosine may also help with wound healing.
In skincare products, Adenosine is usually derived from yeast.
Learn more about AdenosineBeta-Glucan is a soluble polysaccharide (a chain of glucose sugars) sourced from the cells walls of oats, baker's yeast, mushrooms, and seaweed.
It's a rare ingredient that pulls double-duty as a heavy-duty hydrator and skin-soothing repair agent.
On the surface, it acts as a humectant that holds water in place and reduces moisture loss for a plumper, smoother feel, while its anti-inflammatory and antioxidant properties make it a great pick for calming redness or sensitive skin
The more interesting story is underneath:
Despite its large molecular size, oat beta-glucan has been shown to penetrate the epidermis and reach the dermis by slipping between skin cells. Here, it interacts with fibroblasts and macrophages to nudge collagen synthesis and support wound repair.
A small 2005 split-face clinical study of 27 subjects found topical beta-glucan produced measurable reductions in wrinkle depth, height, and roughness after 8 weeks of use.
It is worth noting the trial was small and the penetration testing used frozen, irradiated skin so the anti-aging data is encouraging rather than definitive.
This ingredient gets along with pretty much everything and is typically used around 0.1-1%.
Fungal acne: This ingredient is not a food source for the Malassezia yeast because it is a glucose polysaccharide with no fatty acid or ester component.
Learn more about Beta-GlucanWe don't have a description for Ribose yet.
Ilex Paraguariensis Leaf Extract is a fragrance.
We don't have a description for Copper Lysinate/Prolinate yet.
Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.
Tocopheryl Acetate is commonly found in both skincare and dietary supplements.
Learn more about Tocopheryl AcetateSodium PCA is the sodium salt of pyroglutamic acid. It is naturally occurring in our skin's natural moisturizing factors where it works to maintain hydration.
The PCA stands for pyrrolidone carboxylic acid, a natural amino acid derivative.
This ingredient has skin conditioning, anti-inflammatory, and humectant properties. Humectants help hydrate your skin by drawing moisture from the air. This helps keep your skin moisturized.
Learn more about Sodium PCASodium Lactate is the sodium salt of lactic acid, an AHA. It is a humectant and sometimes used to adjust the pH of a product.
This ingredient is part of our skin's NMF, or natural moisturizing factor. Our NMF is essential for the hydration of our top skin layers and plasticity of skin. NMF also influences our skin's natural acid mantle and pH, which protects our skin from harmful bacteria.
High percentages of Sodium Lactate can have an exfoliating effect.
Fun fact: Sodium Lactate is produced from fermented sugar.
Learn more about Sodium LactatePCA is derived from amino acids and is naturally found in our skin's barrier.
As a humectant, PCA helps draw and hold moisture to the skin. Studies show it is effective at helping the skin stay hydrated long-term.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid or alcohol, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Learn more about Caprylyl GlycolPentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.
The hydrophilic trait of Pentylene Glycol makes it a humectant. As a humectant, Pentylene Glycol helps draw moisture from the air to your skin. This can help keep your skin hydrated.
This property also makes Pentylene Glycol a great texture enhancer. It can also help thicken or stabilize a product.
Pentylene Glycol also acts as a mild preservative and helps to keep a product microbe-free.
Some people may experience mild eye and skin irritation from Pentylene Glycol. We always recommend speaking with a professional about using this ingredient in your routine.
Pentylene Glycol has a low molecular weight and is part of the 1,2-glycol family.
Learn more about Pentylene Glycol1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.ย
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservativesย
Caprylhydroxamic Acid is a chelating agent that helps cosmetics stay fresh, stable, and consistent over time.
Chelating agents help prevent metal ions from binding to other ingredients. This helps prevent unwanted reactions and effects from using the product. It also helps prevent the growth of unwanted microbes in products that contain water.
Caprylhydroxamic Acid is often used with natural antimicrobial products as an alternative to preservatives.
Learn more about Caprylhydroxamic AcidAllantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.
Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.
Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.
It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.
Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.
This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.
Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.
Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.
Learn more about AllantoinGlycine is the smallest amino acid and a key building block of collagen. It's part if your skin's Natural Moisturizing Factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
A study from 2022 found that an amino acid complex featuring taurine, arginine, and glycine significantly reduced skin irritation, improved redness, and accelerated the skin repair process.
Serine is a non-essential amino acid (your body makes it on its own!). It is a major player in your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
Serine is one of your NMF's most abundant components that works as a skin-identical humectant. Its hydroxyl group grabs onto water molecules to boost hydration without any heaviness or occlusion.
Research on a hydrogel with serine confirmed this serine got delivered to your stratum corneum and demonstrated enhanced skin moisturization.
Interestingly serine also helps your skin produce filaggrin, a protein that keeps your skin barrier strong and used to create collagen.
Learn more about SerineAlanine is an amino acid and is already found in the human body. Our skin uses alanine to build collagen, elastin, and keratin.
Valine is an essential amino acid. It is used by our bodies for tissue repair and muscle growth.
An essential amino acid is one in which our bodies cannot naturally produce so we must get them through diet. Foods such as eggs, dairy, red meat, and fish contain valine.
This ingredient can either be derived from an animal product or be synthetically created.
Learn more about ValineIsoleucine is an amino acid that helps reinforce our skin barrier. This amino acid plays a role in creating protein for the body.
Fun fact: Isoleucine is found in meat, fish, dairy, legumes, and nuts.
Proline is a non-essential amino acid, meaning your body can make it on its own. In skincare, it is a skin conditioning ingredient that keeps skin soft and hydrated.
It makes up about 23% of the collagen molecule (collagen is the protein responsible for keeping your skin firm) and is involved in your skin's natural hyaluronic acid production. When applied topically, proline can penetrate the skin fairly well due to its small molecular size.
Reviews of this ingredient have found it to be neither a dermal irritant nor a sensitizer.
Fun fact: Proline can be found in protein-rich foods like meat, fish, eggs, and dairy.
Learn more about ProlineThreonine is an amino-acid. It helps hydrate the skin and has antioxidant benefits.
Our skin uses threonine for creating collagen and elastin. Humans are not able to create threonine and must get it through eating foods such as fish, lentils, poultry, sesame seeds, and more.
Histidine is a semi-essential amino acid used by our bodies to create protein. It has humectant and skin conditioning properties.
Our bodies use histidine to create filaggrin - filaggrin is a structural protein that the skin uses in maintaining skin barrier.
One study found histidine and carnosine to be a dynamic duo for your skin:
Oral histidine has also been found to help with filaggrin-deficit skin disorders such as atopic dermatitis.
Why is it considered a semi-essential amino acid? This is because adults are able to create it but children must get it from their diet.
Learn more about HistidinePhenylalanine is an amino acid. It is a skin soothing and hydrating ingredient. Amino acids play a crucial role in wound healing and skin hydration.
This ingredient is also used to help even out skin tone due to its ability to disrupt the melanin production process.
Two structures of phenylalanine exist: L-phenylalanine and D-phenylalanine. L-phenylalanine is essential, this means our bodies cannot produce it naturally and we must get it from foods. Our bodies convert D-phenylalanine to neurotransmitters, and D-phenylalanine is found in our bodies naturally.
Some foods that contain L-phenylalanine include eggs, soybeans, beef, milk.
Learn more about PhenylalanineAspartic Acid is an amino acid that our bodies produce naturally. It is an antioxidant.
Our body uses Aspartic Acid to help build collagen and elastin. It also plays a role in hydrating skin.
Arginine is a semi-essential amino acid. This just means our bodies can product a bit on its own, but sometimes needs a little boost from food sources.
It is a part of your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
Here's an interesting thing about Arginine: your skin converts it into urea through the Krebs-Henseleit urea cycle. Urea is one of the most effective humectants your skin naturally produces.
A clinical study showed applying 2.5% arginine hydrochloride to atopic dermatitis skin showed significant urea levels in the stratum corneum and improved moisture in just four weeks.
Arginine is also a precursor to nitric oxide; nitric oxide improves microcirculation and supports wound healing and collagen synthesis.
One study found that an amino acid complex containing Arginine reduced skin irritation, improved hydration, and accelerated skin repair in clinical / in-vivo studies.
Arginine itself is an amino acid and not a fatty acid, oil, or ester. On its own, it's not a direct food source for Malassezia, or the yeast that causes fungal acne.
Learn more about ArginineAcetamidoethoxyethanol (long name!) is a recently developed synthetic humectant. The manufacturer claims this humectant can help keep skin moisturized for over 30 hours.
This ingredient helps bind the water molecules in the top layer of our skin using water and keratin. Keratin is a protein found in our skin that protects our skin from bacteria and infection.
Polyglyceryl-3 Methylglucose Distearate is a plant-derived emulsifier whose only job is to keep the oily and watery parts of a formula blended so it doesn't separate into layers.
It's compatible with a wide-range of active ingredients and especially good at making emulsions survive heat/freeze cycles.
Typical use concentrations range from 2-3% and it works across a pH of 4.5-8.5.
This ingredient has been found safe to use in cosmetics and has a low irritation profile.
Because it's build on stearic acid, it may not be fungal acne safe. Stearic acid is a C18 fatty acid that falls within the range (C11-24) that Malassezia can feed on.
Learn more about Polyglyceryl-3 Methylglucose DistearateGlyceryl Stearates isn't fungal acne safe.
We don't have a description for Methylglucoside Phosphate yet.
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumHydroxyacetophenone is antioxidant with skin conditioning and soothing properties. It also boosts the efficiency of preservatives.
Though naturally occuring in Norwegian spruce needles, this ingredient is usually synthetically created.
This ingredient is not irritating or sensitizing. Recent research also suggests it may have skin-brightening effects through tyrosinase inhibition.
Learn more about HydroxyacetophenoneUndecane is an emollient and helps create a lightweight base for products.
Is is not soluble in water and naturally occurring in some species.
Tridecane is a lightweight emollient and fragrancing ingredient. It is a paraffin and often called a silicone alternative.
According to official INCI guidelines, this ingredient is used to give a light odor to raw materials. It is often used as a starter ingredient to create parfum.
This ingredient can be derived from palm oil, or coconut oil. It is also naturally found in certain species of organisms.
According to the NOAA, this ingredient can cause skin sensitivity with prolonged use. However, this warning is taken from the Coast Guard and no studies have been done on this in relation to cosmetics.
Tridecane is not water soluble.
Learn more about TridecaneTetrasodium Glutamate Diacetate is a chelating agent. Chelating agents help prevent metal ions from binding to other ingredients. This helps prevent unwanted effects and reactions from a product. These metal ions may come from water and are found in miniscule amounts.
Tetrasodium Glutamate Diacetate can also help other preservatives be more effective.
Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
In skincare formulas, citric acid can:
While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
Read more about some other popular AHA's here:
Learn more about Citric AcidReviews
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Where it's from
Dermwel is a American brand
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We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about usยท Updated April 1, 2026 • Added by clairehvin