Overview
What it is
Serum with 35 ingredients that contains azelaic acid, niacinamide, peptides and Vitamin C
Cool Features
It is fungal acne (malassezia) safe and reef safe
Suited For
It has ingredients that are good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
It doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates
Fun facts
Dermarium is from Vietnam. This product is used in 11 routines created by our community.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside
Ingredients List
Water
Skin ConditioningHamamelis Virginiana Extract
AntiseborrhoeicNiacinamide
SmoothingAcetyl Glucosamine
Skin ConditioningPropanediol
SolventEthoxydiglycol
HumectantGlycerin
HumectantCystoseira Tamariscifolia Extract
Skin Conditioning1,2-Hexanediol
Skin ConditioningDimethyl Sulfone
SolventLecithin
EmollientEscin
TonicBeta-Sitosterol
Emulsion StabilisingPotassium Azeloyl Diglycinate
Skin ConditioningHypnea Musciformis Extract
Skin ProtectingSargassum Filipendula Extract
Skin ProtectingTetrapeptide-30
Skin ConditioningFerulic Acid
AntimicrobialGinkgo Biloba Leaf Extract
Skin Conditioning3-O-Ethyl Ascorbic Acid
Skin ConditioningAcacia Senegal Gum
MaskingXanthan Gum
EmulsifyingCaprylyl Glycol
EmollientMadecassoside
AntioxidantAsiaticoside
AntioxidantCentella Asiatica Leaf Extract
Skin ConditioningAllantoin
Skin ConditioningSodium Polyacryloyldimethyl Taurate
Emulsion StabilisingHydroxyacetophenone
AntioxidantTetrasodium Glutamate Diacetate
Sodium Metabisulfite
AntioxidantPhenoxyethanol
PreservativeSodium Hydroxide
BufferingSodium Benzoate
MaskingPotassium Sorbate
PreservativeWater, Hamamelis Virginiana Extract, Niacinamide, Acetyl Glucosamine, Propanediol, Ethoxydiglycol, Glycerin, Cystoseira Tamariscifolia Extract, 1,2-Hexanediol, Dimethyl Sulfone, Lecithin, Escin, Beta-Sitosterol, Potassium Azeloyl Diglycinate, Hypnea Musciformis Extract, Sargassum Filipendula Extract, Tetrapeptide-30, Ferulic Acid, Ginkgo Biloba Leaf Extract, 3-O-Ethyl Ascorbic Acid, Acacia Senegal Gum, Xanthan Gum, Caprylyl Glycol, Madecassoside, Asiaticoside, Centella Asiatica Leaf Extract, Allantoin, Sodium Polyacryloyldimethyl Taurate, Hydroxyacetophenone, Tetrasodium Glutamate Diacetate, Sodium Metabisulfite, Phenoxyethanol, Sodium Hydroxide, Sodium Benzoate, Potassium Sorbate
Key Ingredients
Benefits
Concerns
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterHamamelis Virginiana Extract comes from the witch hazel plant.
Unless it is specified to be non-alcohol, many types of witch hazel ingredients are distilled in denatured alcohol.
Witch Hazel has astringent, anti-inflammatory, antioxidant, and antibacterial properties.
The tannin content of witch hazel constrict the appearance of pores by drying out proteins. Witch hazel water gets anti-inflammatory and antibacterial properties from its catechin and gallic acid content.
However, witch hazel may be skin-sensitizing due to the tannin and fragrance compounds.
North American Indigenous groups have used witch hazel to help treat inflammation for centuries.
Learn more about Hamamelis Virginiana ExtractNiacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Learn more about NiacinamideAcetyl Glucosamine is an antioxidant and humectant. It is an amino acid sugar and is naturally found in our skin.
The cool thing about this ingredient? It helps the skin produce hyaluronic acid and boost hydration. It also has antioxidant benefits to protect skin cells.
When paired with niacinamide, Acetyl Glucosamine has been shown to be effective at reducing discoloration.
Learn more about Acetyl GlucosaminePropanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.ย
Itโs often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Learn more about PropanediolEthoxydiglycol is a synthetic solvent.
Solvents are used to keep ingredients together in a product. They can help dissolve ingredients to stable bases or help evenly distribute ingredients throughout the product.
Ethoxydiglycol also helps deliver other key ingredients into the skin.
Learn more about EthoxydiglycolGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinWe don't have a description for Cystoseira Tamariscifolia Extract yet.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.ย
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservativesย
Dimethyl Sulfone is an organic compound that naturally contains sulfur. It is used as a solvent due to its stability. Solvents help mix and stabilize other ingredients.
Studies show taking Dimethyl Sulfone (also known as methylsulfonylmethane or MSM) orally may help reduce the depth of wrinkles. We recommend speaking with a professional if you have any questions or concerns about this ingredient.
Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids.
Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker:
It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers.
Learn more about LecithinWe don't have a description for Escin yet.
Beta-Sitosterol is a plant-derived fatty acid with a structure similar to cholesterol (which naturally occurs in skin). It helps hydrate the skin and stabilize formulations.
This ingredient can be naturally found in fruits, veggies, nuts, and seeds.
Potassium Azeloyl Diglycinate (PAD) comes from the condensation of azelaic acid mixed with glycine.
This ingredient has similar properties to azelaic acid; it can help reduce sebum production and soothe skin. PAD also inhibits tyrosinase activity to help brighten skin. Tyrosinase is an enzyme that controls melanin production.
A study from 2023 found 5% PAD combined with nicotinamide (a form of niacin) effectively reduced melanin production after 6 weeks.
Several studies from the 2010's also show PAD to be effective in alleviating symptoms of Rosacea.
Though this ingredient is considered a gentle active, higher amounts may result in irritation.
Unlike azelaic acid, this ingredient is water-soluble. This property makes it easier to formulate into skincare products.
Learn more about Potassium Azeloyl DiglycinateHypnea Musciformis Extract comes from the red algae called Hypnea musciformis. Hypnea Musciformis is commonly found in the Atlantic, Pacific, and Indian Oceans.
The cell walls of Hypnea Musciformis is rich in carrageenan.
Hypnea Musciformis Extract contains vitamins A, C, and E. It also has calcium, magnesium, sodium, potassium, and iron.
Learn more about Hypnea Musciformis ExtractWe don't have a description for Sargassum Filipendula Extract yet.
Tetrapeptide-30 is a synthetic peptide.
According to a manufacturer, this peptide helps with skin brightening by blocking the process of skin darkening when skin is exposed to UV.
Ferulic Acid is a plant based antioxidant that can be naturally found in the cell walls of grains like rice, oats, and corn. It has antioxidant and antimicrobial properties, and has the ability to boost the performance of other antioxidants as well.
A well-known study found that adding Ferulic Acid to a solution of Vitamins C and E doubled the photoprotection of skin. This is why you'll often see it paired with Vitamin C or Vitamin E serums rather than sold on its own.
A 2025 review of 18 human studies found that using Ferulic Acid (0.5-1%) daily for one to three months showed improvements in:
As far as allergies go, Ferulic acid is generally well-tolerated but can cause an allergic reaction in very rare cases. It's also worth noting that Ferulic acid is often extracted from plant sources like rice bran or wheat bran, so be sure to path test if you have known grain allergies.
Outside of skincare, researchers are also looking into Ferulic Acid for its potential benefits in areas like diabetes, Alzheimer's, and heart health.
Learn more about Ferulic AcidGinkgo Biloba Leaf Extract comes from the leaves of the Ginkgo tree. It has soothing and antioxidant properties.
The leaves of ginkgo contains flavonoids and terpenoids, potent antioxidants. Antioxidants may protect your skin from damage caused by external sources such as pollution.
Its soothing ability comes from a variety of compounds including biflavones, a type of flavonoid. Studies show gingko biloba has strong anti-inflammatory properties.
Fun fact: This tree is native to China and has been used in traditional Chinese medicine for thousands of years.
Learn more about Ginkgo Biloba Leaf ExtractYou might know this ingredient as Ethyl Ascorbic Acid, a more stable version of ascorbic acid.
Like other types of vitamin C, this ingredient has many benefits including reducing wrinkles, skin soothing, dark spot fading, and fighting against free radicals.
3-O-Ethyl Ascorbic Acid interferes with the process of skin darkening, helping to reduce hyperpigmentation. It also encourages the skin to produce more collagen.
Once applied, 3-O-Ethyl Ascorbic Acid is converted to Vitamin C deeper in the skin's layers. This process is slow but makes this ingredient more tolerable for skin.
The optimum pH range for this ingredient is 4 - 5.5
Learn more about 3-O-Ethyl Ascorbic AcidAcacia Senegal Gum has skin soothing, thickening, and formulation stabilizing properties. It comes from the Acacia tree that is native to sub-Saharan Africa.
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumCaprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Learn more about Caprylyl GlycolMadecassoside is one of four active compounds found in Centella asiatica and is one of the main reasons Centella is so effective at calming irritated skin and supporting the moisture barrier.
There's a solid body of peer-reviewed research backing Madecassoside for several skin benefits. Studies have found:
Madecassoside pairs well with other hydrating or antioxidant ingredients like Ascorbic Acid or Hyaluronic Acid.
Learn more about MadecassosideAsiaticoside comes from the super popular skin-soothing ingredient, Centella asiatica. It's the reason centella-based products have a strong reputation for repairing and calming skin, along with its sibling compound Madecassoside.
Research from 2016-2025 supports its role in:
You'll usually find this in concentrations between 0.2-5%.
Learn more about AsiaticosideCentella Asiatica Leaf Extract comes from the leaves of an herb plant native to Southeast Asia. Centella Asiatica is rich in antioxidants and amino acids. It can help reduce irritation and soothe the skin.
Many active components found in centella asiatica, such as Madecassic Acid and Asiaticoside, encourage the skin to naturally produce hyaluronic acid. This helps keep our skin hydrated. Many of these components also show antioxidant activity and may help reduce the signs of aging.
Research shows centella asiatica can help increase Type I collagen production by increasing fibroblast production. Fibroblast helps form connective tissue.
The combination of all these properties makes centella asiatica leaf extract effective at soothing the skin.
Other components of centella asiatica leaf extract include Vitamin A, vitamin C, several B vitamins, and Asiatic Acid.
Recent studies found madecassoside may help prevent damage from UV rays by preventing UV-induced inflammation. Further research is needed.
This plant has been used as a medicine and in food for many centuries. As a medicine, it is used to treat burns, scratches, and wounds.
Learn more about Centella Asiatica Leaf ExtractAllantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.
Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.
Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.
It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.
Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.
This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.
Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.
Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.
Learn more about AllantoinSodium Polyacryloyldimethyl Taurate is a polymer and used to help stabilize other ingredients.
Emulsion stabilizers hold ingredients together, helping to create an even texture throughout the product.
Sodium Polyacryloyldimethyl Taurate can also be used to thicken the texture.
Learn more about Sodium Polyacryloyldimethyl TaurateHydroxyacetophenone is antioxidant with skin conditioning and soothing properties. It also boosts the efficiency of preservatives.
Though naturally occuring in Norwegian spruce needles, this ingredient is usually synthetically created.
This ingredient is not irritating or sensitizing. Recent research also suggests it may have skin-brightening effects through tyrosinase inhibition.
Learn more about HydroxyacetophenoneTetrasodium Glutamate Diacetate is a chelating agent. Chelating agents help prevent metal ions from binding to other ingredients. This helps prevent unwanted effects and reactions from a product. These metal ions may come from water and are found in miniscule amounts.
Tetrasodium Glutamate Diacetate can also help other preservatives be more effective.
Sodium metabisulfite is also known as Sodium Pyrosulfite. It is a preservative, antioxidant, and disinfectant.
As a preservative, it helps stabilize cosmetic formulas without affecting their color or scent.
Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Learn more about Sodium HydroxideSodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.
Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.
Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.
It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.
Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.
We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.
Learn more about Sodium BenzoatePotassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.
This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.
Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.
You'll often find this ingredient used with other preservatives.
Learn more about Potassium SorbateReviews
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Where it's from
Dermarium is a Vietnamese brand
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about usยท Updated September 8, 2025 • Added by betuskincare