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Uriage Dépiderm Anti-Dark Spot Brightening Booster Serum Versus Paula's Choice 25% Vitamin C + Glutathione Clinical Serum

Serum
Serum
French Brand France
American Brand United States

Updated on July 18, 2024

Overview

What they are

These products are both reef safe serums. They have a total of 5 ingredients in common

Cool Features

They both contain Vitamin C

Suited For

They're both likely to be good for anti aging, dry skin, brightening skin, scar healing, dark spots and better texture

Free From

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens or sulfates

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

At a glance

Click on any of the items below to learn more

Notable Ingredients

Benefits

Notable Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Dépiderm Anti-Dark Spot Brightening Booster Serum
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Propanediol Solvent

Propanediol helps absorb ingredients into your skin, boosting their benefits. It can act as an emollient, making your skin softer. Propanediol can help products last longer by boosting the properties of preservatives within the formulation.

Butylene Glycol Humectant, Masking, Skin Conditioning
1 / 0

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

1 Com. / 0 Irr.
Diglycerin Humectant, Skin Conditioning

Diglycerin is a humectant. It is derived from glycerin, which is naturally found in your skin.

Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
1,2-Hexanediol Skin Conditioning, Solvent

1,2-Hexanediol is a multi-tasker ingredient. It acts as a preservative to increase shelf-life and can aid other preservatives in preventing microbe growth. 1,2-Hexanediol also helps the skin retain moisture as a humectant.

Ascorbyl Glucoside Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps brighten skin Icon
Vitamin CVitamin C Icon AntioxidantAntioxidant Icon 6 Benefits

Ascorbyl Glucoside is a stable form of Vitamin C. It is created by combining glucose from starch.

3-O-Ethyl Ascorbic Acid Skin Conditioning
Vitamin C IconHelps reduce Skin Redness IconGood for Skin Texture IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing Icon
Vitamin CVitamin C Icon 5 Benefits

You might know this ingredient as Ethyl Ascorbic Acid, a more stable version of ascorbic acid.

Polysorbate 20 Emulsifying
0 / 0 Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.

0 Com. / 0 Irr.
Very Disliked Full details ->
Sodium Citrate Buffering, Masking

Sodium Citrate is the sodium salts of citric acid. In skincare, it is used to alter pH levels and acts as a preservative.

Xanthan Gum Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

Disliked Full details ->
Sodium Hydroxide Buffering

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

Dipotassium Glycyrrhizate Humectant, Skin Conditioning
Helps reduce Skin Redness IconHelps reduce irritation IconGood for Dark Spots Icon
3 Benefits

Dipotassium Glycyrrhizate comes from licorice root.

Niacinamide Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconGood for Minimizing Pores IconGood for Dark Spots IconHelps fight Acne IconHelps brighten skin Icon
NiacinamideNiacinamide Icon 6 Benefits

Niacinamide has emerged as an all-star ingredient due to its many benefits.

Maltodextrin Absorbent, Emulsion Stabilising, Skin Conditioning

Maltodextrin is a polysaccharide. It is derived from starch such as rice, corn, wheat, or potato starch.

Citric Acid Buffering, Masking
AHA IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconHelps brighten skin IconMay cause irritation IconMay worsen Rosacea Icon
AHAAHA Icon 4 Benefits 2 Concerns

Citric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).

Disliked Full details ->
Sucrose Dilaurate Emollient, Emulsifying, Skin Conditioning
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Sucrose Dilaurate isn't fungal acne safe.

Unknown Full details ->
Sodium Cocoyl Glutamate Cleansing

Sodium Cocoyl Glutamate is a gentle cleanser and surfactant. It is the sodium salt of the Cocoyl Glutamic Acid and comes from coconut oil. As a surfactant, it helps lift dirt and oil to be washed away.

Pisum Sativum Extract Skin Conditioning, Skin Protecting

We don't have a description for Pisum Sativum Extract.

25% Vitamin C + Glutathione Clinical Serum
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Tetrahexyldecyl Ascorbate Antioxidant, Skin Conditioning
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconHelps with Anti-Aging IconGood for Dark Spots IconHelps brighten skin Icon
Vitamin CVitamin C Icon AntioxidantAntioxidant Icon 5 Benefits

Tetrahexyldecyl Ascorbate is a form of Vitamin C.

Dimethicone Emollient, Skin Conditioning, Skin Protecting
1 / 0 Silicon Icon
SiliconSilicon Icon

Dimethicone is a silicone used for making products smooth and silky. It also has the added benefit of sealing in hydration. The amount of dimethicone found in beauty products is considered safe and non-comedogenic, meaning it won't clog pores.

1 Com. / 0 Irr.
Very Disliked Full details ->
Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
C9-12 Alkane Solvent

C9-12 Alkane is synethically created using alkanes, or paraffins. It is added to products as a solvent. This means its main purpose is to help dissolve ingredients and create even texture.

Unknown Full details ->
Ascorbyl Glucoside Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps brighten skin Icon
Vitamin CVitamin C Icon AntioxidantAntioxidant Icon 6 Benefits

Ascorbyl Glucoside is a stable form of Vitamin C. It is created by combining glucose from starch.

Silica Abrasive, Absorbent
Exfoliant IconMay worsen Eczema IconMay worsen Rosacea Icon
ExfoliantExfoliant Icon 2 Concerns

Silica is a mineral naturally found in our skin. It helps to thicken and smooth the texture of a product. It also acts as an agent for other ingredients by increasing the absorption of other ingredients into the skin.

Disliked Full details ->
Pyrus Malus Fruit Extract Skin Conditioning

Pyrus Malus Fruit Extract is extract from Apples. Apples are rich in Vitamin C, sugars, and antioxidants.

Hydrogenated Lecithin Emulsifying, Skin Conditioning

Hydrogenated Lecithin is created from the hydrogenation of lecithin. Hydrogenation is a chemical reaction between molecule hydrogen and another element.

Polyglyceryl-6 Polyricinoleate Emulsifying
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Polyglyceryl-6 Polyricinoleate isn't fungal acne safe.

Unknown Full details ->
Acrylates/C10-30 Alkyl Acrylate Crosspolymer Emulsion Stabilising

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken and improve the texture of products.

Disliked Full details ->
Xanthan Gum Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

Disliked Full details ->
Oryza Sativa Bran Extract Skin Conditioning, Skin Protecting

Oryza Sativa Bran Extract comes from the outer layer of a rice kernel. It is a byproduct of milling rice, or the operation to produce a whole grain rice product.

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Emulsion Stabilising

This is a synthetic polymer. It helps improve the texture of products by adding thickness and gel-like feel.

Disliked Full details ->
Cetyl Alcohol Emollient, Emulsifying, Emulsion Stabilising
2 / 2 Fatty Alcohol Icon
Fatty AlcoholFatty Alcohol Icon

Cetyl Alcohol is a fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product.

2 Com. / 2 Irr.
Very Disliked Full details ->
Caprylyl Glycol Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

Lysine Carboxymethyl Cysteinate Skin Conditioning

We don't have a description for Lysine Carboxymethyl Cysteinate.

Unknown Full details ->
Coco-Caprylate Emollient
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Coco-Caprylate is created from fatty coconut alcohol and caprylic acid.

Very Disliked Full details ->
Tocopherol Antioxidant, Masking, Skin Conditioning
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin IconMay cause irritation Icon
Vitamin EVitamin E Icon AntioxidantAntioxidant Icon 4 Benefits May cause irritationMay cause irritation Icon

Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.

0-3 Com. / 0-3 Irr.
Glutathione

Glutathione is an antioxidant naturally found in our bodies. It is made up of three amino acids: glycine, cysteine, and glutamic acid.

Sodium Citrate Buffering, Masking

Sodium Citrate is the sodium salts of citric acid. In skincare, it is used to alter pH levels and acts as a preservative.

Sodium Phytate

Sodium Phytate is the synthetic salt form of phytic acid. Phytic acid is an antioxidant and can be found in plant seeds.

Hexylene Glycol Emulsifying, Skin Conditioning, Solvent
0-2 / 0-1

Hexylene Glycol is a surfactant. Glycols are a class of alcohols. Hexylene Glycol is a surfactant and emulsifier.

0-2 Com. / 0-1 Irr.
Disliked Full details ->
Ethylhexylglycerin Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

Helianthus Annuus Seed Extract Skin Conditioning

Helianthus Annuus Seed Extract comes from sunflower seeds.

Unknown Full details ->
Urea Buffering, Humectant, Skin Conditioning
Helps hydrate Dry Skin IconGood for Skin Texture IconMay worsen Eczema IconMay worsen Rosacea Icon
2 Benefits 2 Concerns

Urea is also called carbamide and is the diamide of carbonic acid. In cosmetics, urea is used to hydrate the skin. It also provides exfoliation in higher concentrations.

Mannitol Humectant, Masking, Moisturising

Mannitol is a sugar alcohol. It is a humectant and moisturizes the skin. In vitro (not tested on a living organism), mannitol displays antioxidant properties.

Caprylic/Capric Triglyceride Masking, Skin Conditioning

Caprylic/Capric Triglyceride is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.

Sodium PCA Humectant, Skin Conditioning
0 / 0

Sodium PCA is the sodium salt of pyroglutamic acid and is naturally occurring on human skin.

0 Com. / 0 Irr.
Rosmarinus Officinalis Leaf Extract Antimicrobial, Masking, Skin Conditioning

Rosmarinus Officinalis Leaf Extract comes from rosemary. Rosemary is native to the Mediterranean.

Polysorbate 60 Emulsifying
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Polysorbate 60 is used to help stabilize products. It is a surfactant and emulsifier. These properties help keep ingredients together in a product. Surfactants help reduce surface tension between ingredients with different states, such as liquids and solids. Emulsifiers help prevent oils and waters from separating.

Very Disliked Full details ->
Sorbitan Isostearate Emulsifying
1-2 / 0 Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Sorbitan Isostearate is an emulsifer and cleaning agent. It is created from isostearic acid and sorbitol.

1-2 Com. / 0 Irr.
Very Disliked Full details ->
Trehalose Humectant, Moisturising

Trehalose is a disaccharide made of two glucose molecules (glucose is sugar!). Trehalose is used to help moisturize skin. It also has antioxidant properties.

Ascorbic Acid Antioxidant, Buffering, Masking
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps brighten skin Icon
Vitamin CVitamin C Icon AntioxidantAntioxidant Icon 6 Benefits

Ascorbic Acid is is pure Vitamin C. This form makes up the largest amount of vitamin C found naturally in our skin.

Glucose Humectant

Glucose is a simple sugar and is the most important source of energy in all organisms.

Vanilla Planifolia Fruit Extract Skin Conditioning, Skin Protecting, Smoothing

Vanilla Planifolia Fruit Extract comes from the vanilla orchid native to central America. It is a skin-soothing ingredient.

Polyquaternium-51 Skin Conditioning

Polyquaternium-51 is a polymer salt. It helps hydrate the skin by creating a film on top. This film traps moisture in, keeping your skin soft and hydrated.

Ergothioneine Antioxidant
Antioxidant Icon
AntioxidantAntioxidant Icon

Ergothioneine is an antioxidant.

Triacetin Antimicrobial, Masking, Solvent
0 / 0

Triacetin comes from glycerin and acetic acid. It has antimicrobial properties.

0 Com. / 0 Irr.
Unknown Full details ->
Sodium Hyaluronate Humectant, Skin Conditioning
0 / 0 Hyaluronic Acid Icon
Hyaluronic AcidHyaluronic Acid Icon

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

0 Com. / 0 Irr.
Phenoxyethanol Preservative
Preservative Icon
PreservativePreservative Icon

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

Very Disliked Full details ->

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent
Loved

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Humectant, Skin Conditioning, Skin Protecting
Loved

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Antioxidant
Liked

Ascorbyl Glucoside is a stable form of Vitamin C. It is created by combining glucose from starch.

When applied to skin, Ascorbyl Glucoside turns into Ascorbic Acid.

Ascorbyl Glucoside is an antioxidant. Antioxidants help fight free-radicals, or molecules that may damage skin cells.

It can help to reduce redness, improve skin texture, reduce the effects of aging, reduce the visibility of dark spots, and brighten skin.

Read more about other types of Vitamin C:

Learn more about Ascorbyl Glucoside
Buffering, Masking
Mixed

Sodium Citrate is the sodium salts of citric acid. In skincare, it is used to alter pH levels and acts as a preservative.

Sodium Citrate helps maintain the pH of a product. Normal pH level of skin is slightly acidic (~4.75-5.5). The acidity of our skin is maintained by our glands and skin biome. Being slightly acidic allows our skin to create an "acid mantle". This acid mantle is a thin barrier that protects our skin from bacteria and contaminants.

Sodium Citrate is a chelating agent. It neutralizes metal ions from water and prevents them from binding to other ingredients. This ensures the other ingredients will not be altered.

Learn more about Sodium Citrate
Emulsifying, Emulsion Stabilising, Gel Forming
Disliked

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Learn more about Xanthan Gum

Ingredient Ratings

Here's what our community thinks of the ingredients in these products.

Dépiderm Anti-Dark Spot Brightening Booster Serum
10
5
3
1
liked
mixed
disliked
not rated
25% Vitamin C + Glutathione Clinical Serum
20
5
11
5
liked
mixed
disliked
not rated

When to use

3 Routines
67% use in am
33% use in pm
100% use every day
50 Routines
80% use in am
20% use in pm
96% use every day
When to use See routines that use it ->