The Ordinary Multi-Peptide + HA Serum Versus ISANA Peptide Serum
Updated on July 18, 2024
Overview
What they are
These products are both cruelty-free and reef safe serums. They have a total of 10 ingredients in common
Cool Features
They both contain hyaluronic acid and peptides
Suited For
They're both likely to be good for anti aging, dry skin, brightening skin, scar healing, dark spots and better texture
Free From
They both do not contain any harsh alcohols, common allergens, fragrances, parabens, silicones or sulfates
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
The Ordinary Multi-Peptide + HA Serum 51 ingredients
ISANA Peptide Serum 21 ingredients
What's inside (and what isn't)
What's inside (and what isn't)
At a glance
Click on any of the items below to learn more
The Ordinary Multi-Peptide + HA Serum 51 ingredients
ISANA Peptide Serum 21 ingredients
Benefits
Concerns
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningGlycerin
Humectant
Lactococcus Ferment Lysate
Skin ConditioningAcetyl Hexapeptide-8
Humectant
Pentapeptide-18
Skin Conditioning
Palmitoyl Tripeptide-1
Skin Conditioning
Palmitoyl Tetrapeptide-7
Skin Conditioning
Palmitoyl Tripeptide-38
Skin Conditioning
Dipeptide Diaminobutyroyl Benzylamide Diacetate
Skin Conditioning
Acetylarginyltryptophyl Diphenylglycine
Skin ConditioningSodium Hyaluronate Crosspolymer
Humectant
Sodium Hyaluronate
Humectant
Allantoin
Skin Conditioning
Glycine
Buffering
Alanine
MaskingSerine
Masking
Valine
MaskingIsoleucine
Skin ConditioningProline
Skin ConditioningThreonine
Histidine
Humectant
Phenylalanine
Masking
Arginine
Masking
Aspartic Acid
Masking
Trehalose
Humectant
Fructose
Humectant
Glucose
Humectant
Maltose
MaskingUrea
Buffering
Sodium PCA
Humectant
PCA
Humectant
Sodium Lactate
BufferingCitric Acid
Buffering
Hydroxypropyl Cyclodextrin
MaskingSodium Chloride
Masking
Sodium Hydroxide
BufferingButylene Glycol
Humectant
Pentylene Glycol
Skin ConditioningAcacia Senegal Gum
MaskingXanthan Gum
EmulsifyingCarbomer
Emulsion StabilisingPolysorbate 20
Emulsifying
PPG-26-Buteth-26
Skin ConditioningPEG-40 Hydrogenated Castor Oil
Emulsifying
Trisodium Ethylenediamine Disuccinate
Ethoxydiglycol
HumectantSodium Benzoate
Masking
Caprylyl Glycol
EmollientEthylhexylglycerin
Skin ConditioningPhenoxyethanol
Preservative
Chlorphenesin
Antimicrobial
Water, Glycerin, Lactococcus Ferment Lysate, Acetyl Hexapeptide-8, Pentapeptide-18, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-38, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Acetylarginyltryptophyl Diphenylglycine, Sodium Hyaluronate Crosspolymer, Sodium Hyaluronate, Allantoin, Glycine, Alanine, Serine, Valine, Isoleucine, Proline, Threonine, Histidine, Phenylalanine, Arginine, Aspartic Acid, Trehalose, Fructose, Glucose, Maltose, Urea, Sodium PCA, PCA, Sodium Lactate, Citric Acid, Hydroxypropyl Cyclodextrin, Sodium Chloride, Sodium Hydroxide, Butylene Glycol, Pentylene Glycol, Acacia Senegal Gum, Xanthan Gum, Carbomer, Polysorbate 20, PPG-26-Buteth-26, PEG-40 Hydrogenated Castor Oil, Trisodium Ethylenediamine Disuccinate, Ethoxydiglycol, Sodium Benzoate, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol, Chlorphenesin
Water
Skin ConditioningMethylpropanediol
SolventGlycerin
Humectant
Propylene Glycol
Humectant
Hydrogenated Starch Hydrolysate
HumectantHydrolyzed Hyaluronic Acid
Humectant
Acetyl Hexapeptide-8
Humectant
Ethylhexylglycerin
Skin ConditioningXanthan Gum
EmulsifyingAspartic Acid
Masking
Soluble Collagen
Humectant
Sodium Salicylate
Preservative
Caprylyl Glycol
EmollientSodium Benzoate
Masking
Citric Acid
Buffering
Sodium Hydroxide
BufferingTetrasodium Iminodisuccinate
Fumaric Acid
BufferingSodium Citrate
BufferingMaleic Acid
BufferingMalic Acid
Buffering
Water, Methylpropanediol, Glycerin, Propylene Glycol, Hydrogenated Starch Hydrolysate, Hydrolyzed Hyaluronic Acid, Acetyl Hexapeptide-8, Ethylhexylglycerin, Xanthan Gum, Aspartic Acid, Soluble Collagen, Sodium Salicylate, Caprylyl Glycol, Sodium Benzoate, Citric Acid, Sodium Hydroxide, Tetrasodium Iminodisuccinate, Fumaric Acid, Sodium Citrate, Maleic Acid, Malic Acid
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Acetyl Hexapeptide-8, commonly known as Argireline, is a popular peptide in skincare. It’s often referred to as a “Botox-like” ingredient because it helps reduce muscle movement.
By relaxing these micro-movements, Argireline may help minimize the appearance of fine lines and wrinkles. That said, it’s not as powerful as Botox, and research on its long-term effectiveness is still limited.
Beyond smoothing, Argireline may also support collagen production. Collagen is the protein that helps keep your skin firm, bouncy, and well-hydrated by strengthening the skin barrier.
So while Argireline isn’t a miracle fix, it can be a helpful addition to a routine focused on both prevention and skin health.
Read more about other common types of peptides here:
Learn more about Acetyl Hexapeptide-8Aspartic Acid is an amino acid that our bodies produce naturally. It is an antioxidant.
Our body uses Aspartic Acid to help build collagen and elastin. It also plays a role in hydrating skin.
Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.
It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.
Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.
This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.
Learn more about Caprylyl GlycolCitric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).
As an AHA, Citric Acid removes the top layer of skin cells from the newer layer of skin underneath. This helps skin to remove dark spots and even out skin tone.
If you spot Citric Acid near the end of an ingredient list, it's likely there as a pH adjuster rather than an active ingredient.
Read more about some other popular AHA's here:
Learn more about Citric AcidEthylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinSodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.
Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.
Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.
It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.
Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.
We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.
Learn more about Sodium BenzoateSodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Learn more about Sodium HydroxideWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumIngredient Ratings
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When to use
The Ordinary Multi-Peptide + HA Serum 51 ingredients
ISANA Peptide Serum 21 ingredients
Reviews
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