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The Creme Shop Pro-Youth 2x Collagen Protein Ampoule Serum - Klean Beauty Versus Ipse Cosmetic Botonix Age-Defying Ampoule

Ampoule
Ampoule
American Brand United States
Korean Brand South Korea

Overview

What they are

These products are both reef safe ampoules. They have a total of 14 ingredients in common

Cool Features

They both contain hyaluronic acid

Suited For

They're both likely to be good for anti aging, dry skin, brightening skin, sensitive skin and dark spots

Free From

They both do not contain any common allergens, parabens or sulfates

What's Inside

They both contain fragrances and oils

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

At a glance

Click on any of the items below to learn more

Benefits

Concerns

Notable Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Pro-Youth 2x Collagen Protein Ampoule Serum - Klean Beauty
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Butylene Glycol Humectant, Masking, Skin Conditioning
1 / 0

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

1 Com. / 0 Irr.
Hydrolyzed Collagen Emollient, Humectant, Skin Conditioning
Helps with Anti-Aging Icon
Helps with Anti-AgingHelps with Anti-Aging Icon

Hydrolyzed collagen has a misleading name because it is actually a mixture of various proteins/peptides. This ingredient has skin hydrating properties.

Methyl Gluceth-20 Humectant, Moisturising

Methyl Gluceth-20 is a humectant. Humectants help draw moisture from the air to your skin.

1,2-Hexanediol Skin Conditioning, Solvent

1,2-Hexanediol is a multi-tasker ingredient. It acts as a preservative to increase shelf-life and can aid other preservatives in preventing microbe growth. 1,2-Hexanediol also helps the skin retain moisture as a humectant.

Oryza Sativa Extract Absorbent, Skin Conditioning
Helps with Anti-Aging IconGood for Dark Spots Icon
2 Benefits

Oryza Sativa Extract comes from the rice grain, Oryza sativa. Rice extract has wound healing, antioxidant, anti-inflammatory, and hydrating properties.

Disliked Full details ->
Oryza Sativa Seed Protein Antioxidant
Antioxidant Icon
AntioxidantAntioxidant Icon

Oryza Sativa Seed Protein is an antioxidant.

Unknown Full details ->
Hydrolyzed Soy Protein Extract Skin Conditioning

We don't have a description for Hydrolyzed Soy Protein Extract.

Unknown Full details ->
Hydrolyzed Oat Protein Skin Conditioning

We don't have a description for Hydrolyzed Oat Protein.

Unknown Full details ->
Hydrolyzed Milk Protein Skin Conditioning

We don't have a description for Hydrolyzed Milk Protein.

Unknown Full details ->
Hydrolyzed Elastin Emollient, Skin Conditioning

We don't have a description for Hydrolyzed Elastin.

Unknown Full details ->
Hydrolyzed Keratin Humectant, Skin Conditioning

Hydrolyzed Keratin is derived from keratin. Keratin is a large protein that is naturally found in our hair and skin.

Hydrolyzed Silk Humectant, Skin Conditioning

You can find hydrolyzed silk in both haircare and skincare products. According to a manufacturer, it can help improve skin and hair hydration.

Juglans Regia Seed Extract Skin Conditioning

We don't have a description for Juglans Regia Seed Extract.

Unknown Full details ->
Vaccinium Angustifolium Fruit Extract Skin Protecting, Soothing

We don't have a description for Vaccinium Angustifolium Fruit Extract.

Illicium Verum Fruit Extract Perfuming, Skin Conditioning
Fragrance Icon
FragranceFragrance Icon

Illicium Verum Fruit Extract is a fragrance.

Chenopodium Quinoa Seed Extract Skin Conditioning

We don't have a description for Chenopodium Quinoa Seed Extract.

Unknown Full details ->
Sodium Hyaluronate Humectant, Skin Conditioning
0 / 0 Hyaluronic Acid Icon
Hyaluronic AcidHyaluronic Acid Icon

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

0 Com. / 0 Irr.
Biosaccharide Gum-1 Skin Conditioning

Biosaccharide Gum-1 is a sugar created from fermented sorbitol. Most sorbitol is made from potato starch.

Erythritol Humectant, Moisturising, Skin Conditioning

You might know this ingredient as a sugar substitute in foods. It is a sugar alcohol with humectant properties.

Betaine Humectant, Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon
3 Benefits

Betaine is a common humectant (a substance that promotes retention of moisture). It's known to be gentle on the skin and can help balance hydration.

Carbomer Emulsion Stabilising, Gel Forming
1 / 0

Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.

1 Com. / 0 Irr.
Disliked Full details ->
Arginine Masking, Skin Conditioning
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Arginine is an amino acid that is important for human development. Your body uses is it to produce hair keratin and skin collagen.

Glyceryl Acrylate/Acrylic Acid Copolymer Humectant

Glyceryl Acrylate/Acrylic Acid Copolymer is made up of glycerin and polyacrylic acid. It helps hydrate your skin as a humectant.

Pvm/Ma Copolymer Emulsion Stabilising

We don't have a description for Pvm/Ma Copolymer.

Unknown Full details ->
Peg-60 Hydrogenated Castor Oil Emulsifying
Oil IconNot safe for Fungal Acne Icon
OilOil Icon Not safe for Fungal AcneNot safe for Fungal Acne Icon

Peg-60 Hydrogenated Castor Oil comes from hydrogenated castor oil. It is a solubilizer and emulsifier.

Very Disliked Full details ->
Caprylyl Glycol Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

Ethylhexylglycerin Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

Allantoin Skin Conditioning, Skin Protecting, Soothing
0 / 0 Helps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon
3 Benefits

Allantoin plays a role in soothing and moisturizing the skin. Because of this, it is often added to products with strong active ingredients.

0 Com. / 0 Irr.
Disodium EDTA

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

Disliked Full details ->
Parfum Masking, Perfuming
Fragrance IconMay worsen Eczema IconMay worsen Rosacea Icon
FragranceFragrance Icon 2 Concerns

Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.

Very Disliked Full details ->
Botonix Age-Defying Ampoule
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Cyclopentasiloxane Emollient, Skin Conditioning, Solvent
Silicon Icon
SiliconSilicon Icon

Cyclopentasiloxane is a silicone used to improve texture and trap moisture. An easier name for this is D5.

Disliked Full details ->
Butylene Glycol Humectant, Masking, Skin Conditioning
1 / 0

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

1 Com. / 0 Irr.
Glycol Humectant, Solvent
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Glycol isn't fungal acne safe.

Unknown Full details ->
Alcohol Denat. Antimicrobial, Astringent, Masking
Alcohol IconCan worsen Dry Skin IconMay worsen Oily Skin IconMay cause irritation IconMay worsen Eczema IconMay worsen Rosacea Icon
AlcoholAlcohol Icon 5 Concerns

Alcohol Denat. is an alcohol with a denaturant property. It is created by mixing ethanol with other additives.

Very Disliked Full details ->
Betaine Humectant, Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon
3 Benefits

Betaine is a common humectant (a substance that promotes retention of moisture). It's known to be gentle on the skin and can help balance hydration.

Cyclohexasiloxane Emollient, Skin Conditioning, Solvent
Silicon Icon
SiliconSilicon Icon

Cyclohexasiloxane is a type of silicone more commonly known as D6. It is an emollient and solvent.

Disliked Full details ->
Methyl Gluceth-20 Humectant, Moisturising

Methyl Gluceth-20 is a humectant. Humectants help draw moisture from the air to your skin.

Dipropylene Glycol Masking, Solvent

Dipropylene Glycol is a synthetically created stabilizer and solvent. It is a part of the glycol class in the alcohol family.

Disliked Full details ->
Glycereth-26 Humectant
0 / 0

Glycereth-26 is a synthetic ingredient and polyethylene glycol ether of Glycerin. Glycerin is already naturally found in your skin and helps keep your skin moisturized.

0 Com. / 0 Irr.
Silica Abrasive, Absorbent
Exfoliant IconMay worsen Eczema IconMay worsen Rosacea Icon
ExfoliantExfoliant Icon 2 Concerns

Silica is a mineral naturally found in our skin. It helps to thicken and smooth the texture of a product. It also acts as an agent for other ingredients by increasing the absorption of other ingredients into the skin.

Disliked Full details ->
Octyldodeceth-16 Emulsifying

Octyldodeceth-16 comes from the fatty-alcohol Octyldodecanol.

Unknown Full details ->
Peg-60 Hydrogenated Castor Oil Emulsifying
Oil IconNot safe for Fungal Acne Icon
OilOil Icon Not safe for Fungal AcneNot safe for Fungal Acne Icon

Peg-60 Hydrogenated Castor Oil comes from hydrogenated castor oil. It is a solubilizer and emulsifier.

Very Disliked Full details ->
Polyacrylate-13

Polyacrylate-13 is a type of acrylate polymer. Acrylate polymers are commonly used as adhesives in cosmetics.

Disliked Full details ->
Polyisobutene

Polyisobutene is a synthetic polymer made from isobutene.

Disliked Full details ->
Chlorphenesin Antimicrobial, Preservative
Preservative Icon
PreservativePreservative Icon

Chlorphenesin is a synthetic preservative. It helps protect a product against bacteria in order to extend shelf life. In most cases, Chlorphenesin is paired with other preservatives such as phenoxyethanol and caprylyl glycol.

Disliked Full details ->
Dimethiconol Emollient, Moisturising

Dimethiconol is a silicone that resembles the popular dimethicone. Like other silicones, it is an emollient. Emollients create a thin film on skin to prevent moisture from escaping.

Disliked Full details ->
Caprylyl Glycol Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

Ethylhexylglycerin Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

Argania Spinosa Kernel Oil Emollient, Skin Conditioning
Oil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon
OilOil Icon Helps hydrate Dry SkinHelps hydrate Dry Skin Icon Not safe for Fungal AcneNot safe for Fungal Acne Icon

Argania Spinosa Kernel Oil is derived from the kernels of the argania spinosa tree. You may know it as argan oil.

Carbomer Emulsion Stabilising, Gel Forming
1 / 0

Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.

1 Com. / 0 Irr.
Disliked Full details ->
Parfum Masking, Perfuming
Fragrance IconMay worsen Eczema IconMay worsen Rosacea Icon
FragranceFragrance Icon 2 Concerns

Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.

Very Disliked Full details ->
Arginine Masking, Skin Conditioning
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Arginine is an amino acid that is important for human development. Your body uses is it to produce hair keratin and skin collagen.

Xanthan Gum Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

Disliked Full details ->
Ceramide Ns Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconHelps with Anti-Aging Icon
CeramideCeramide Icon 4 Benefits

Ceramide NS is a type of Ceramide. Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. They are known for their ability to hold water and thus are a great ingredient for dry skin.

1,2-Hexanediol Skin Conditioning, Solvent

1,2-Hexanediol is a multi-tasker ingredient. It acts as a preservative to increase shelf-life and can aid other preservatives in preventing microbe growth. 1,2-Hexanediol also helps the skin retain moisture as a humectant.

Adenosine Skin Conditioning
Helps with Anti-Aging IconGood for Scar Healing Icon
2 Benefits

Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.

Polysorbate 20 Emulsifying
0 / 0 Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.

0 Com. / 0 Irr.
Very Disliked Full details ->
Sorbitan Isostearate Emulsifying
1-2 / 0 Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Sorbitan Isostearate is an emulsifer and cleaning agent. It is created from isostearic acid and sorbitol.

1-2 Com. / 0 Irr.
Very Disliked Full details ->
Caramel Cosmetic Colorant, Masking

We don't have a description for Caramel.

Disodium EDTA

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

Disliked Full details ->
Dipotassium Glycyrrhizate Humectant, Skin Conditioning
Helps reduce Skin Redness IconHelps reduce irritation IconGood for Dark Spots Icon
3 Benefits

Dipotassium Glycyrrhizate comes from licorice root.

Sodium Hyaluronate Humectant, Skin Conditioning
0 / 0 Hyaluronic Acid Icon
Hyaluronic AcidHyaluronic Acid Icon

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

0 Com. / 0 Irr.
Cyclotetrasiloxane Emollient, Skin Conditioning, Solvent
Silicon Icon
SiliconSilicon Icon

Cyclotetrasiloxane is a type of silicone.

Very Disliked Full details ->
Beta Vulgaris Extract Skin Protecting

Beta Vulgaris Extract comes from the beet root plant. Beet Root has high Vitamin C content.

Unknown Full details ->
CI 77480 Cosmetic Colorant

We don't have a description for CI 77480.

Unknown Full details ->
Citrus Limon Fruit Extract Masking, Skin Conditioning
May cause irritation Icon
May cause irritationMay cause irritation Icon

Citrus Limon Fruit Extract comes from lemons. While lemon extract is exfoliating and antimicrobial, it can also cause skin sensitivity.

Very Disliked Full details ->
Tripropylene Glycol Antioxidant, Emulsion Stabilising, Humectant
Antioxidant Icon
AntioxidantAntioxidant Icon

Tripropylene Glycol is an antioxidant.

Unknown Full details ->
Propylene Glycol Humectant, Skin Conditioning, Solvent
0 / 0 May worsen Eczema Icon
May worsen EczemaMay worsen Eczema Icon

Propylene Glycol is an odorless, colorless liquid. As a humectant, it helps skin retain moisture. It also aids in delivering active ingredients.

0 Com. / 0 Irr.
Disliked Full details ->
Eleutherococcus Senticosus Root Extract Astringent

This root is more commonly know as Siberian ginseng.

Unknown Full details ->
Acetyl Hexapeptide-8 Humectant, Skin Conditioning
Peptide Icon
PeptidePeptide Icon

Acetyl Hexapeptide-8 is a peptide. A common name for this peptide is Argireline.

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent
Loved

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Humectant, Skin Conditioning, Skin Protecting
Loved

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Humectant, Masking, Skin Conditioning
Mixed

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

  • It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
  • It is a humectant, which means that it helps attract moisture into the skin.
  • It helps improve product application.

Overall, Butylene Glycol is a safe and well-rounded ingredient. It is unlikely to irritate skin, and works well with pretty much all other ingredients.

Humectant, Moisturising
Liked

Methyl Gluceth-20 is a humectant. Humectants help draw moisture from the air to your skin.

It is created by combining polyethylene glycol with glucose.

Skin Conditioning, Solvent
Mixed

1,2-Hexanediol is a multi-tasker ingredient. It acts as a preservative to increase shelf-life and can aid other preservatives in preventing microbe growth. 1,2-Hexanediol also helps the skin retain moisture as a humectant.

In products that are water-based, this ingredient can help stabilize perfumes and fragrances. It can also help make the texture of products softer and more smooth.

Humectant, Skin Conditioning
Loved

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Learn more about Sodium Hyaluronate
Humectant, Skin Conditioning
Loved

Betaine is a common humectant (a substance that promotes retention of moisture). It's known to be gentle on the skin and can help balance hydration.

Betaine is best for improving hydration and soothing irritated skin. Studies show betaine may help with uneven skin tones.

Betaine is naturally created in the skin and body. The form found within cosmetic products can be either plant-dervied or synthetic.

Learn more about Betaine
Emulsion Stabilising, Gel Forming
Disliked

Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.

Carbomer is commonly found in many types of cosmetics products. It is found to be safe in concentrations up to 15%. However, a high amount of carbomer can cause pilling or balling up of products. Most products contain 1% of less of carbomer.

Masking, Skin Conditioning
Mixed

Arginine is an amino acid that is important for human development. Your body uses is it to produce hair keratin and skin collagen.

As a cosmetic ingredient, Arginine has antioxidant properties and can also help repair damaged skin. This ingredient is derived either synthetically or from animals.

Arginine isn't fungal acne safe when used in the presence of other lipids (fats, fatty acids, oils, esters, etc). Oils and fats occur naturally within the skin, so take caution when using Arginine if you're prone to fungal acne.

Learn more about Arginine
Emulsifying
Very Disliked

Peg-60 Hydrogenated Castor Oil comes from hydrogenated castor oil. It is a solubilizer and emulsifier.

As a solubilizer, it helps dissolve ingredients into a water-based version. It is also an emulsifer. Emulsifier help prevent oils and water from separating. Both these properties help create evenly-spread and uniform products.

Basically, Peg-60 Hydrogenated Castor Oil helps hold ingredients together.

Learn more about Peg-60 Hydrogenated Castor Oil
Emollient, Humectant, Skin Conditioning
Liked

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.

Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.

This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.

Learn more about Caprylyl Glycol
Skin Conditioning
Mixed

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.

Disliked

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.

Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.

Learn more about Disodium EDTA
Masking, Perfuming
Very Disliked

Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.

Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.

In the US, the alternative name for parfum is 'fragrance'.

The term 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.

For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.

One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.

Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.

Parfum can also be used to mask or cover an unpleasant scent.

The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.

Learn more about Parfum

Ingredient Ratings

Here's what our community thinks of the ingredients in these products.

Pro-Youth 2x Collagen Protein Ampoule Serum - Klean Beauty
13
6
5
8
liked
mixed
disliked
not rated
Botonix Age-Defying Ampoule
11
6
19
6
liked
mixed
disliked
not rated

When to use

1 Routine
100% use in am
0% use in pm
100% use every day