This anti-aging treatment is formulated around Sh-Oligopeptide-1 and Acetyl Hexapeptide-8 to soften the look of wrinkles and refine skin texture.
This anti-aging serum is formulated around Acetyl Hexapeptide-8 and Bakuchiol to soften the look of wrinkles and strengthen the skin barrier.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
No concerns
Ingredients Side-by-side
Water
Skin ConditioningSh-Oligopeptide-1
Skin Conditioning
Sh-Oligopeptide-2
Skin Conditioning
N-Prolyl Palmitoyl Tripeptide-56 Acetate
Skin Conditioning
Sh-Polypeptide-1
Skin Conditioning
Sh-Polypeptide-9
Skin Conditioning
Tetrapeptide-21
Skin Conditioning
Caprooyl Tetrapeptide-3
Skin Protecting
Acetyl Hexapeptide-8
Humectant
Acetyl Hexapeptide-38
Skin Conditioning
Palmitoyl Tripeptide-38
Skin Conditioning
Acetyl Tetrapeptide-2
Skin Conditioning
Trifluoroacetyl Tripeptide-2
Skin Conditioning
Propanediol
Solvent
Sodium Hyaluronate
Humectant
1,2-Hexanediol
Skin Conditioning
Caprylyl Glycol
Emollient
Hydroxyacetophenone
Antioxidant
Tetrasodium Glutamate Diacetate
Water, Sh-Oligopeptide-1, Sh-Oligopeptide-2, N-Prolyl Palmitoyl Tripeptide-56 Acetate, Sh-Polypeptide-1, Sh-Polypeptide-9, Tetrapeptide-21, Caprooyl Tetrapeptide-3, Acetyl Hexapeptide-8, Acetyl Hexapeptide-38, Palmitoyl Tripeptide-38, Acetyl Tetrapeptide-2, Trifluoroacetyl Tripeptide-2, Propanediol, Sodium Hyaluronate, 1,2-Hexanediol, Caprylyl Glycol, Hydroxyacetophenone, Tetrasodium Glutamate Diacetate
Water
Skin ConditioningAcetyl Hexapeptide-8
Humectant
Sodium Hyaluronate
Humectant
Butylene Glycol
Humectant
Bakuchiol
Antimicrobial
Copper Tripeptide-1
Skin Conditioning
Polyglutamic Acid
Skin Conditioning
Palmitoyl Pentapeptide-4
Skin Conditioning
Palmitoyl Tripeptide-1
Skin Conditioning
Palmitoyl Tetrapeptide-7
Skin Conditioning
Palmitoyl Tripeptide-38
Skin Conditioning
Palmitoyl Tripeptide-5
Skin Conditioning
Ceramide NP
Skin Conditioning
Ceramide AP
Skin Conditioning
Ceramide EOP
Skin Conditioning
Bisabolol
Antioxidant
Phytosphingosine
Skin Conditioning
Ferulic Acid
Antimicrobial
Camellia Sinensis Leaf Extract
Antimicrobial
Olea Europaea Leaf Extract
Perfuming
Salvia Officinalis Leaf Extract
CleansingBeta-Glucan
Skin Conditioning
Avena Sativa Kernel Extract
Abrasive
Propanediol
Solvent
Pentapeptide-34 Trifluoroacetate
Emollient
Cholesterol
Emollient
Panthenol
Skin Conditioning
Niacinamide
Smoothing
Allantoin
Skin Conditioning
Arginine
Masking
1,2-Hexanediol
Skin Conditioning
Escin
TonicPhenoxyethanol
Preservative
Pentylene Glycol
Skin Conditioning
Xanthan Gum
EmulsifyingCarbomer
Emulsion StabilisingTocopherol
Antioxidant
Hydrolyzed Hyaluronic Acid
Humectant
Hyaluronic Acid
Humectant
Sodium Acetylated Hyaluronate
Humectant
PEG-9 Diglycidyl Ether/Sodium Hyaluronate Crosspolymer
Skin ConditioningHydroxypropyltrimonium Hyaluronate
Hydrolyzed Sodium Hyaluronate
Skin Conditioning
Potassium Hyaluronate
Skin ConditioningEthylhexylglycerin
Skin ConditioningMenaquinone-7
AntiseborrhoeicSodium Benzoate
Masking
Potassium Sorbate
Preservative
Citric Acid
Buffering
Water, Acetyl Hexapeptide-8, Sodium Hyaluronate, Butylene Glycol, Bakuchiol, Copper Tripeptide-1, Polyglutamic Acid, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-38, Palmitoyl Tripeptide-5, Ceramide NP, Ceramide AP, Ceramide EOP, Bisabolol, Phytosphingosine, Ferulic Acid, Camellia Sinensis Leaf Extract, Olea Europaea Leaf Extract, Salvia Officinalis Leaf Extract, Beta-Glucan, Avena Sativa Kernel Extract, Propanediol, Pentapeptide-34 Trifluoroacetate, Cholesterol, Panthenol, Niacinamide, Allantoin, Arginine, 1,2-Hexanediol, Escin, Phenoxyethanol, Pentylene Glycol, Xanthan Gum, Carbomer, Tocopherol, Hydrolyzed Hyaluronic Acid, Hyaluronic Acid, Sodium Acetylated Hyaluronate, PEG-9 Diglycidyl Ether/Sodium Hyaluronate Crosspolymer, Hydroxypropyltrimonium Hyaluronate, Hydrolyzed Sodium Hyaluronate, Potassium Hyaluronate, Ethylhexylglycerin, Menaquinone-7, Sodium Benzoate, Potassium Sorbate, Citric Acid
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative".
It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time.
The comparison to Botox does have limits because the molecule is water-loving and relatively large.
Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles.
So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging.
A 12 week human study of a multi-ingredient regimen containing this ingredient saw:
While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone).
Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations.
Learn more about Acetyl Hexapeptide-8This synthetic, signal peptide has unique skin conditioning properties in that is a matrikine-mimetic compound.
First of all, Palmitoyl Tripeptide-38 is a signal peptide; signal peptides tell the body to create more collagen.
What is a matrikine-mimetic compound?
This peptide has the ability to mimic matrikines in skin. Our skin created matrikines by breaking down matrix proteins into peptides.
Matrikines play a role in:
Though further research is needed, this ingredient seems pretty promising. In one study, women over the age of 40 with visible photoaging used a vitamin C serum with this ingredient for 56 days (15% ascorbid acid, 5 ppm palmitoyl tripeptide‐38). The results found improvement in skin roughness and skin tone.
This peptide is also part of the famous Matrixyl synthe’6, a blend of ingredients that also includes glycerin, water, and hydroxypropyl cyclodextrin.
Learn more about Palmitoyl Tripeptide-38Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Learn more about PropanediolSodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Learn more about Sodium HyaluronateWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water
