SkinCeuticals Discoloration Defense Dark Spot Serum
Mesoestetic Cosmelan 2 Facial Cream
Versus

SkinCeuticals Discoloration Defense Dark Spot Serum Versus Mesoestetic Cosmelan 2 Facial Cream

Serum
Facial Treatment
American Brand United States
Spanish Brand Spain

Updated on January 22, 2025

Overview

Cool Features

They both contain niacinamide

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots

Free From

They both do not contain any common allergens, fragrances, oils or parabens

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

New Comparison

Ingredient Info

Click any item below to learn more and see relevant ingredients

SkinCeuticals Discoloration Defense Dark Spot Serum 14 ingredients

Mesoestetic Cosmelan 2 Facial Cream 48 ingredients

What's inside (and what isn't)

What's inside (and what isn't)

At a glance

Click on any of the items below to learn more

SkinCeuticals Discoloration Defense Dark Spot Serum 14 ingredients

Mesoestetic Cosmelan 2 Facial Cream 48 ingredients

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Discoloration Defense Dark Spot Serum

Water

Skin Conditioning

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Niacinamide

Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Hydroxyethylpiperazine Ethane Sulfonic Acid

Buffering

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Tranexamic Acid

Astringent
Helps reduce irritation IconGood for Dark Spots IconGood for Scar Healing Icon

Propylene Glycol

Humectant
0 / 0 Helps hydrate Dry Skin IconMay worsen Eczema IconMay worsen Rosacea Icon

Hydroxyethyl Urea

Humectant
Helps hydrate Dry Skin Icon

Kojic Acid

Antioxidant
Antioxidant IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne Icon

Caprylyl Glycol

Emollient

Allantoin

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

Chlorphenesin

Antimicrobial
Preservative Icon

Xanthan Gum

Emulsifying

Disodium EDTA

Water, Butylene Glycol, Niacinamide, Hydroxyethylpiperazine Ethane Sulfonic Acid, Glycerin, Tranexamic Acid, Propylene Glycol, Hydroxyethyl Urea, Kojic Acid, Caprylyl Glycol, Allantoin, Chlorphenesin, Xanthan Gum, Disodium EDTA

Cosmelan 2 Facial Cream

Water

Skin Conditioning

Caprylic/Capric Triglyceride

Masking
Helps hydrate Dry Skin Icon

Azelaic Acid

Buffering
Good for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne Icon

Aloe Barbadensis Leaf Juice

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Sodium Ascorbyl Phosphate

Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps brighten skin Icon

Titanium Dioxide

Cosmetic Colorant
0 / 0 Mineral UV Filter IconNon-Reef-Safe Icon

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Kojic Acid

Antioxidant
Antioxidant IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne Icon

Poloxamer 407

Emulsifying

Glyceryl Stearate

Emollient
1 / 0 Not safe for Fungal Acne Icon

Ethoxydiglycol

Humectant
0 / 0

Hydroxypropyl Starch Phosphate

Alpha-Arbutin

Antioxidant
Antioxidant IconGood for Dark Spots IconGood for Scar Healing Icon

Butylene Glycol Dicaprylate/Dicaprate

Emollient

Cyclomethicone

Emollient
0 / 0 Silicon Icon

Ethylhexyl Methoxycinnamate

UV Absorber
0 / 0 Chemical UV Filter IconMay cause irritation IconNon-Reef-Safe Icon

Niacinamide

Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Di-C12-13 Alkyl Malate

Emollient

Ceteareth-25

Cleansing

PEG-8 Beeswax

Emulsifying
Not safe for Fungal Acne Icon

Stearic Acid

Cleansing
2-3 / 0 May worsen Oily Skin IconNot safe for Fungal Acne Icon

Tocopheryl Acetate

Antioxidant
0 / 0 Vitamin E IconAntioxidant Icon

Retinyl Palmitate

Skin Conditioning
1-3 / 1-3 Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconNot safe for Fungal Acne IconMay worsen Rosacea Icon

Dimethicone

Emollient
1 / 0 Silicon Icon

Alcohol

Antimicrobial
Alcohol IconCan worsen Dry Skin IconMay worsen Oily Skin IconMay cause irritation IconMay worsen Eczema IconMay worsen Rosacea Icon

Behenyl Alcohol

Emollient
Fatty Alcohol Icon

Disodium Ethylene Dicocamide PEG-15 Disulfate

Cleansing
Sulfate Icon

Citric Acid

Buffering
AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconHelps brighten skin IconMay worsen Rosacea Icon

Ascorbic Acid

Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps brighten skin Icon

Bisabolol

Masking
Helps reduce Skin Redness IconHelps reduce irritation IconGood for Dark Spots Icon

Salicylic Acid

Masking
BHA IconPreservative IconGood for Oily Skin IconGood for Minimizing Pores IconHelps fight Acne IconHelps brighten skin IconCan worsen Dry Skin IconMay worsen Eczema IconMay worsen Rosacea Icon

Sclerotium Gum

Emulsion Stabilising

Sorbitan Stearate

Emulsifying
0 / 1 Not safe for Fungal Acne Icon

Stearyl Dimethicone

Emollient
Silicon Icon

Sodium Lauroyl Lactylate

Emulsifying

Aminoethylphosphinic Acid

Skin Conditioning

Rumex Occidentalis Extract

Skin Conditioning

Acacia Senegal Gum

Masking

Glyceryl Stearate Citrate

Emollient
Not safe for Fungal Acne Icon

Glycyrrhiza Glabra Root Extract

Bleaching
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Dark Spots Icon

Allantoin

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

Sodium Metabisulfite

Antioxidant
Antioxidant IconPreservative Icon

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Phytic Acid

AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconHelps brighten skin IconMay worsen Rosacea Icon

Xanthan Gum

Emulsifying

Phenoxyethanol

Preservative
Preservative Icon

Manganese Oxide

UV Absorber

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Water, Caprylic/Capric Triglyceride, Azelaic Acid, Aloe Barbadensis Leaf Juice, Sodium Ascorbyl Phosphate, Titanium Dioxide, Glycerin, Kojic Acid, Poloxamer 407, Glyceryl Stearate, Ethoxydiglycol, Hydroxypropyl Starch Phosphate, Alpha-Arbutin, Butylene Glycol Dicaprylate/Dicaprate, Cyclomethicone, Ethylhexyl Methoxycinnamate, Niacinamide, Di-C12-13 Alkyl Malate, Ceteareth-25, PEG-8 Beeswax, Stearic Acid, Tocopheryl Acetate, Retinyl Palmitate, Dimethicone, Alcohol, Behenyl Alcohol, Disodium Ethylene Dicocamide PEG-15 Disulfate, Citric Acid, Ascorbic Acid, Bisabolol, Salicylic Acid, Sclerotium Gum, Sorbitan Stearate, Stearyl Dimethicone, Sodium Lauroyl Lactylate, Aminoethylphosphinic Acid, Rumex Occidentalis Extract, Acacia Senegal Gum, Glyceryl Stearate Citrate, Glycyrrhiza Glabra Root Extract, Allantoin, Sodium Metabisulfite, Butylene Glycol, Phytic Acid, Xanthan Gum, Phenoxyethanol, Manganese Oxide, Tocopherol

Ingredient Ratings

Here's what our community thinks of the ingredients in these products.

Discoloration Defense Dark Spot Serum
10
10
10
liked
mixed
disliked
Unlock with Premium
Cosmelan 2 Facial Cream
10
10
10
liked
mixed
disliked
not rated
Unlock with Premium

When to use

SkinCeuticals Discoloration Defense Dark Spot Serum 14 ingredients

Mesoestetic Cosmelan 2 Facial Cream 48 ingredients

159 Routines
53% use in am
47% use in pm
94% use every day
When to use See routines that use it ->
5 Routines
20% use in am
80% use in pm
60% use every day
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