SKIN1004 Madagascar Centella Poremizing Fresh Ampoule Versus Sulwhasoo Concentrated Ginseng Renewing Rescue Ampoule
This smoothing ampoule is formulated around Centella Asiatica Extract and Acetyl Hexapeptide-8 to refine skin texture and soften the look of wrinkles.
This anti-aging ampoule is formulated around Adenosine and Panax Ginseng Root Extract to soften the look of wrinkles and calm redness.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
No concerns
Ingredients Side-by-side
Water
Skin ConditioningButylene Glycol
Humectant
Propanediol
Solvent
1,2-Hexanediol
Skin Conditioning
Aloe Barbadensis Leaf Extract
Emollient
Centella Asiatica Extract
Cleansing
Glycereth-26
Humectant
Hydroxyacetophenone
Antioxidant
Glycerin
Humectant
Carbomer
Emulsion StabilisingTromethamine
BufferingPanthenol
Skin Conditioning
Ethylhexylglycerin
Skin ConditioningDisodium EDTA
Dipotassium Glycyrrhizate
Humectant
Ammonium Polyacryloyldimethyl Taurate
Emulsion StabilisingBiosaccharide Gum-1
Humectant
Hyaluronic Acid
Humectant
Hydrolyzed Hyaluronic Acid
Humectant
Sodium Hyaluronate
Humectant
Hydroxyethylcellulose
Emulsion StabilisingChamomilla Recutita Flower Extract
Masking
Mineral Salts
Skin ConditioningTripeptide-3
Skin Conditioning
Acetyl Hexapeptide-8
Humectant
Acetyl Octapeptide-3
Humectant
Copper Tripeptide-1
Skin Conditioning
Palmitoyl Pentapeptide-4
Skin Conditioning
Palmitoyl Tetrapeptide-7
Skin Conditioning
Palmitoyl Tripeptide-1
Skin Conditioning
Tripeptide-1
Skin Conditioning
Tripeptide-2
Skin Conditioning
Water, Butylene Glycol, Propanediol, 1,2-Hexanediol, Aloe Barbadensis Leaf Extract, Centella Asiatica Extract, Glycereth-26, Hydroxyacetophenone, Glycerin, Carbomer, Tromethamine, Panthenol, Ethylhexylglycerin, Disodium EDTA, Dipotassium Glycyrrhizate, Ammonium Polyacryloyldimethyl Taurate, Biosaccharide Gum-1, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate, Hydroxyethylcellulose, Chamomilla Recutita Flower Extract, Mineral Salts, Tripeptide-3, Acetyl Hexapeptide-8, Acetyl Octapeptide-3, Copper Tripeptide-1, Palmitoyl Pentapeptide-4, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Tripeptide-1, Tripeptide-2
Water
Skin ConditioningButylene Glycol
Humectant
Glycerin
Humectant
PEG/PPG-17/6 Copolymer
SolventDipropylene Glycol
HumectantPolysorbate 80
Emulsifying
1,2-Hexanediol
Skin Conditioning
PEG-150 Distearate
Emulsifying
Diethoxyethyl Succinate
SolventBis-PEG-18 Methyl Ether Dimethyl Silane
EmollientPolysorbate 20
Emulsifying
Olive Oil PEG-8 Esters
Emollient
Parfum
Masking
Dipotassium Glycyrrhizate
Humectant
Pentylene Glycol
Skin Conditioning
Ethylhexylglycerin
Skin ConditioningAdenosine
Skin Conditioning
Disodium EDTA
Methoxy PEG-114/Polyepsilon Caprolactone
BufferingXanthan Gum
EmulsifyingSodium Chloride
MaskingPanax Ginseng Root Extract
Emollient
Achillea Millefolium Extract
CleansingHoney
Humectant
Rehmannia Glutinosa Root Extract
Skin ConditioningHydrolyzed Ginseng Saponins
Skin ConditioningPaeonia Lactiflora Root Extract
Skin ConditioningLilium Candidum Bulb Extract
Skin ConditioningPolygonatum Odoratum Rhizome Extract
Skin ConditioningPhenoxyethanol
Preservative
Nelumbo Nucifera Flower Extract
Skin ConditioningBHT
Antioxidant
Glycyrrhiza Glabra Root Extract
Bleaching
Tocopherol
Antioxidant
Caprylyl Glycol
Emollient
Acetyl Heptapeptide-4
Humectant
Acetyl Hexapeptide-8
Humectant
Sodium Hydroxide
BufferingAcetyl Octapeptide-3
Humectant
Water, Butylene Glycol, Glycerin, PEG/PPG-17/6 Copolymer, Dipropylene Glycol, Polysorbate 80, 1,2-Hexanediol, PEG-150 Distearate, Diethoxyethyl Succinate, Bis-PEG-18 Methyl Ether Dimethyl Silane, Polysorbate 20, Olive Oil PEG-8 Esters, Parfum, Dipotassium Glycyrrhizate, Pentylene Glycol, Ethylhexylglycerin, Adenosine, Disodium EDTA, Methoxy PEG-114/Polyepsilon Caprolactone, Xanthan Gum, Sodium Chloride, Panax Ginseng Root Extract, Achillea Millefolium Extract, Honey, Rehmannia Glutinosa Root Extract, Hydrolyzed Ginseng Saponins, Paeonia Lactiflora Root Extract, Lilium Candidum Bulb Extract, Polygonatum Odoratum Rhizome Extract, Phenoxyethanol, Nelumbo Nucifera Flower Extract, BHT, Glycyrrhiza Glabra Root Extract, Tocopherol, Caprylyl Glycol, Acetyl Heptapeptide-4, Acetyl Hexapeptide-8, Sodium Hydroxide, Acetyl Octapeptide-3
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative".
It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time.
The comparison to Botox does have limits because the molecule is water-loving and relatively large.
Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles.
So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging.
A 12 week human study of a multi-ingredient regimen containing this ingredient saw:
While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone).
Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations.
Learn more about Acetyl Hexapeptide-8Acetyl Octapeptide-3 is a synthetic peptide also commonly known as SNAP-8. It is a lab-made peptide often marketed as a gentler, topical alternative to Botox.
It works by mimicking part of a protein involved in muscle contractions, which may help relax facial tension and reduce the appearance of fine lines (mostly around the eyes and forehead).
It’s considered a “next-gen” version of Argireline (Acetyl Hexapeptide-8), an older peptide with more research behind it that also supports collagen production.
SNAP-8 showed slightly better results than Argireline in one small manufacturer-funded study, but there’s limited independent research. Plus, most tests use concentrations higher than what’s typically found in skincare products.
This ingredient might offer a subtle smoothing effect but it won't don’t deliver the dramatic results of actual Botox injections.
Think of it more like a supporting actor in your skincare lineup.
Learn more about Acetyl Octapeptide-3Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolDipotassium Glycyrrhizate comes from licorice root.
Extracts of licorice have demonstrated to have antibacterial, anti‐inflammatory, antiviral, antioxidant properties.
One component, glabridin, has extra potent antioxidant and soothing properties. It has also been found to block pigmentation from UVB rays in guinea pigs.
Licorice Root also contains a flavonoid. Flavonoids are a natural substance from in plants. Flavonoids also have antioxidant properties.
Another component, glycyrrhizin, has been found to have anti-inflammatory and antimicrobial benefits. This may make licorice root extract effective at treating acne. However, more research is needed to support this.
Liquiritin is one of the flavone compounds found in licorice. It has been found to help lighten skin by preventing tyrosinase from reacting with tyrosine. When the two react, protein is converted to melanin. Melanin is the substance in your body that gives your features pigmentation.
Licorice root is native to Southern Europe and Asia. It has been used in traditional Chinese medicine to help with respiratory issues.
Learn more about Dipotassium GlycyrrhizateDisodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Learn more about Disodium EDTAEthylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water
