Overview
What they are
These products are both reef safe serums. They have a total of 9 ingredients in common
Cool Features
They both contain niacinamide, peptides, retinoid and Vitamin E
Suited For
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
They both do not contain any harsh alcohols, common allergens, parabens, silicones or sulfates
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Meisani Blue Elixir Retinol Serum 28 ingredients
SkinMedica Age Defense Retinol Complex 1.0 34 ingredients
At a glance
Click on any of the items below to learn more
Meisani Blue Elixir Retinol Serum 28 ingredients
SkinMedica Age Defense Retinol Complex 1.0 34 ingredients
Notable Ingredients
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Concerns
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Ingredients Side-by-side
Aloe Barbadensis Leaf Water is an aqueous solution of the steam distillate obtained from the leaves of the aloe, Aloe barbadensis, Liliaceae.
6 Benefits
Niacinamide has emerged as an all-star ingredient due to its many benefits.
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
Antioxidant Helps hydrate Dry Skin
Avena Sativa Kernel Extract is is derived from colloidal oatmeal. Besides being a healthy breakfast, oats have many benefits in skincare too.
Spirulina Platensis Extract comes from the alga called Spirulina platensis. It has wound-healing, antioxidant, and soothing properties.
Glycyrrhiza Glabra Root Extract is an extract of the roots of Licorice. It has been found to have several benefits such as skin hydrating, conditioning, and soothing.
Helps with Anti-Aging
Copper Tripeptide-1 is a peptide naturally found in body fluids. Peptides are building blocks for protein.
Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.
Antioxidant 4 Benefits May cause irritation
Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.
Cholesterol is a class of organic molecules called lipids. It helps hydrate your skin and is essential to having a healthy skin barrier.
Allantoin plays a role in soothing and moisturizing the skin. Because of this, it is often added to products with strong active ingredients.
8 Benefits 3 Concerns
Retinol is a gold-standard ingredient for anti-aging. It is a form of Vitamin A and belongs to the class of retinoids that also includes tretinoin.
Hydrogenated Lecithin is created from the hydrogenation of lecithin. Hydrogenation is a chemical reaction between molecule hydrogen and another element.
Antioxidant Helps brighten skin
Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
Paeonia Suffruticosa Root Extract comes from the Paeonia Suffruticosa plant known as the Peony.
Scutellaria Baicalensis Root Extract comes from the Baikal skullcap or Chinese skullcap plant. This plant is native to Northeast Asia and can be found in China, Mongolia, Korea, and Siberia.
Caprylic/Capric Triglyceride is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.
Cetearyl Olivate is an emulsifier and texture enhancer. It is derived from the fatty acids of olive oil and Cetearyl alcohol, and is biodegradable.
Sodium Citrate is the sodium salts of citric acid. In skincare, it is used to alter pH levels and acts as a preservative.
Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.
1,2-Hexanediol is a multi-tasker ingredient. It acts as a preservative to increase shelf-life and can aid other preservatives in preventing microbe growth. 1,2-Hexanediol also helps the skin retain moisture as a humectant.
Aloe Barbadensis Leaf Water, Niacinamide, Glycerin, Water, Avena Sativa Kernel Extract, Linum Usitatissimum Seed Extract, Oenothera Biennis Flower Extract, Spirulina Platensis Extract, Glycyrrhiza Glabra Root Extract, Copper Tripeptide-1, Squalane, Tocopherol, Cholesterol, Allantoin, Retinol, Hydrogenated Lecithin, Tocopheryl Acetate, Paeonia Suffruticosa Root Extract, Scutellaria Baicalensis Root Extract, Calcium Gluconate, Caprylic/Capric Triglyceride, Butylene Glycol, Caprylyl Glycol, Cetearyl Olivate, Sorbitan Olivate, Sodium Citrate, Carbomer, 1,2-Hexanediol
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
Not safe for Fungal Acne
Glycine Soja Oil comes from the soybean. Glycine Soja is native to eastern Asia.
Caprylic/Capric Triglyceride is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.
6 Benefits
Niacinamide has emerged as an all-star ingredient due to its many benefits.
Polyacrylate-13 is a type of acrylate polymer. Acrylate polymers are commonly used as adhesives in cosmetics.
Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.
8 Benefits 3 Concerns
Retinol is a gold-standard ingredient for anti-aging. It is a form of Vitamin A and belongs to the class of retinoids that also includes tretinoin.
Not safe for Fungal Acne
Palmitoyl Tripeptide-8 isn't fungal acne safe and is a peptide.
Antioxidant 4 Benefits May cause irritation
Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.
Bisabolol is pimarily used to add fragrance to a product. However, it is also famous for helping soothe skin.
Not safe for Fungal Acne
Squalene is naturally found in plants and animals, including our skin and sebum. It is a lipid our bodies naturally produce and makes up about 10-12% of the oil on our skin. Our skin produces squalene to keep itself naturally hydrated.
Antioxidant Helps brighten skin
Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
Oryza Sativa Bran Cera is wax from the outer layer of a rice kernel. It is a byproduct of milling rice, or the operation to produce a whole grain rice product.
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Cetyl Palmitate is a wax-like substance.
Laureth-23 is created by reacting ethylene oxide with Lauryl Alcohol.
Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
Dicaprylyl Ether is created from caprylic acid. It is a texture-enhancer and emollient.
Lauryl Alcohol is a type of fatty alcohol. It is derived from palm kernel oil or coconut oil.
Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.
Disodium EDTA plays a role in making products more stable by aiding other preservatives.
Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent germ and microbial growth. By itself, it has a scent that is similar to that of a rose.
Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
Water, Cetyl Ethylhexanoate, Glycine Soja Oil, Caprylic/Capric Triglyceride, Niacinamide, Polyacrylate-13, Squalane, Retinol, Palmitoyl Tripeptide-8, Dunaliella Salina Extract, Magnolia Grandiflora Bark Extract, Tocopherol, Tocotrienols, Ceramide 3, Bisabolol, Phytosterols, Squalene, Tocopheryl Acetate, Oryza Sativa Bran Cera, Glycerin, Polysorbate 20, Butylene Glycol, Cetyl Palmitate, Laureth-23, Trideceth-6 Phosphate, Sodium Hydroxide, Dicaprylyl Ether, Lauryl Alcohol, Polyisobutene, Dextran, Potassium Sorbate, Disodium EDTA, Phenoxyethanol, Ethylhexylglycerin
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Niacinamide has emerged as an all-star ingredient due to its many benefits.
It is known to treat acne by reducing inflammation. It also helps fade dark-spots and strengthen the skin by promoting the growth of the ceramide barrier.
Other benefits include smoothing wrinkles and minimizing redness.
The cherry on top? Niacinamide can also help build keratin, a protein that keeps skin firm.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
Niacinamide can be mixed with other ingredients to boost benefits. For instance, it has shown to be effective when used with copper, folic acid, and zinc to treat acne.
Learn more about NiacinamideGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. Talk about multi-purpose! If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterSqualane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.
Because squalane boosts hydration in the skin, it also comes with plenty of benefits: it is an antioxidant and can help fight free radicals and skin damage. Squalane is also found to have a detoxifying effect when applied.
Squalane comes from squalene, which occurs naturally within the sebum of our skin. It is one of the oils our skin produces to keep itself hydrated. Squalane is the hydrogenated version of squalene and has a longer shelf life.
Research shows that squalane is non-irritating (even at 100% concentration).
In general, it's a fantastic ingredient. It does a great job at hydrating the skin, and it's suitable for those with sensitive skin.
The source of squalane may impact malassezia / fungal acne. This is because olive oil derived squalane can contain impurities such as fatty acids and plant waxes. Sugarcane derived squalane is recommended for anyone with malassezia concerns.
Is squalane vegan?
This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.
Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.
Read more about squalene with an "e".
Learn more about SqualaneTocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.
Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.
Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.
You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.
There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.
Learn more about TocopherolRetinol is a gold-standard ingredient for anti-aging. It is a form of Vitamin A and belongs to the class of retinoids that also includes tretinoin.
Why is retinol famous?
It has the most scientific studies backing up its skin benefits out of all the non-prescription ingredients.
Retinol is proven to:
This is why retinol is effective at removing wrinkles, fading dark spots, treating acne, and reducing the appearance of pores.
Studies show retinol is less effective when exposed to UV. Be sure to look for appropriate packaging to keep your retinol potent (similar to Vitamin C).
Using retinol or any retinoids will increase sun-sensitivity in the first few months. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.
We recommend speaking with a medical professional about using this ingredient during pregnancy.
Retinol may cause irritation in some people, so be sure to patch test. Experts recommend 'ramping up' retinol use: start using this ingredient once a week and work up to using it daily.
Read about Tretinoin
Learn more about RetinolTocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.
Tocopheryl Acetate is commonly found in both skincare and dietary supplements.
Learn more about Tocopheryl AcetateCaprylic/Capric Triglyceride is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.
Within a product, Caprylic Triglyceride can thicken the product and make spreadability easier by dissolving clumping compounds. An added benefit of Caprylic Triglyceride is its antioxidant properties.
Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid. Caprylic Triglyceride has not been found to be toxic for human use in concentrations under 50%.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this.
Learn more about Caprylic/Capric TriglycerideButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
- It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
- It is a humectant, which means that it helps attract moisture into the skin.
- It helps improve product application.
Overall, Butylene Glycol is a safe and well-rounded ingredient. It is unlikely to irritate skin, and works well with pretty much all other ingredients.
Ingredient Ratings
Here's what our community thinks of the ingredients in these two products.
When to use
Meisani Blue Elixir Retinol Serum 28 ingredients
SkinMedica Age Defense Retinol Complex 1.0 34 ingredients
Reviews
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