Cetaphil Optimal Hydration Skin Replenishing Water Gel Versus The Ordinary Natural Moisturizing Factors + Beta Glucan
This barrier-repair moisturizer is formulated around Panthenol and Niacinamide to strengthen the skin barrier and hydrate skin.
This barrier-repair moisturizer is formulated around Beta-Glucan to strengthen the skin barrier and hydrate skin.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningGlycerin
HumectantDimethicone
EmollientPropanediol
SolventPanthenol
Skin ConditioningNiacinamide
SmoothingOctyldodecanol
EmollientSodium Polyacryloyldimethyl Taurate
Emulsion StabilisingHydrolyzed Hyaluronic Acid
HumectantSodium Hyaluronate
HumectantPolyglutamic Acid
Skin ConditioningAllantoin
Skin ConditioningXylitylglucoside
HumectantAnhydroxylitol
HumectantDistarch Phosphate
AbsorbentHydroxyacetophenone
AntioxidantAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingCaprylyl Glycol
Emollient1,2-Hexanediol
Skin ConditioningTrehalose
HumectantUrea
BufferingXylitol
HumectantXanthan Gum
EmulsifyingPentylene Glycol
Skin ConditioningSerine
MaskingSodium Hydroxide
BufferingPantolactone
HumectantAlgin
MaskingDisodium Phosphate
BufferingGlyceryl Polyacrylate
Pullulan
Globularia Alypum Leaf Extract
Skin ConditioningCitric Acid
BufferingPotassium Phosphate
BufferingWater, Glycerin, Dimethicone, Propanediol, Panthenol, Niacinamide, Octyldodecanol, Sodium Polyacryloyldimethyl Taurate, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate, Polyglutamic Acid, Allantoin, Xylitylglucoside, Anhydroxylitol, Distarch Phosphate, Hydroxyacetophenone, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Caprylyl Glycol, 1,2-Hexanediol, Trehalose, Urea, Xylitol, Xanthan Gum, Pentylene Glycol, Serine, Sodium Hydroxide, Pantolactone, Algin, Disodium Phosphate, Glyceryl Polyacrylate, Pullulan, Globularia Alypum Leaf Extract, Citric Acid, Potassium Phosphate
Water
Skin ConditioningPPG-24-Glycereth-24
EmulsifyingPropanediol
SolventBetaine
HumectantBeta-Glucan
Skin ConditioningArginine
MaskingGlycine
BufferingAlanine
MaskingSerine
MaskingProline
Skin ConditioningThreonine
Glutamic Acid
HumectantLysine Hcl
Skin ConditioningGlucose
HumectantMaltose
MaskingFructose
HumectantTrehalose
HumectantXylitol
HumectantAnhydroxylitol
HumectantXylitylglucoside
HumectantSodium PCA
HumectantPCA
HumectantSodium Lactate
BufferingUrea
BufferingAllantoin
Skin ConditioningSodium Hyaluronate
HumectantPhospholipids
Skin ConditioningSphingolipids
EmollientGlycerin
HumectantPentylene Glycol
Skin ConditioningAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingSodium Hydroxide
BufferingSodium Chloride
MaskingSodium Citrate
BufferingCitric Acid
BufferingTocopherol
AntioxidantP-Anisic Acid
MaskingAminomethyl Propanol
BufferingPhenoxyethanol
PreservativeChlorphenesin
AntimicrobialWater, PPG-24-Glycereth-24, Propanediol, Betaine, Beta-Glucan, Arginine, Glycine, Alanine, Serine, Proline, Threonine, Glutamic Acid, Lysine Hcl, Glucose, Maltose, Fructose, Trehalose, Xylitol, Anhydroxylitol, Xylitylglucoside, Sodium PCA, PCA, Sodium Lactate, Urea, Allantoin, Sodium Hyaluronate, Phospholipids, Sphingolipids, Glycerin, Pentylene Glycol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Sodium Hydroxide, Sodium Chloride, Sodium Citrate, Citric Acid, Tocopherol, P-Anisic Acid, Aminomethyl Propanol, Phenoxyethanol, Chlorphenesin
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products.
As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied.
It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin.
A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record.
Learn more about Acrylates/C10-30 Alkyl Acrylate CrosspolymerAllantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.
Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.
Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.
It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.
Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.
This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.
Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.
Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.
Learn more about AllantoinThis ingredient is created from dehydrating xylitol in acidic conditions. Xylitol is a famous sugar and humectant.
Much like its predecessor, anhydroxylitol is a humectant. Humectants attract and hold water to moisturize the skin.
This ingredient is most commonly found in a popular trio called Aquaxyl. Aquaxyl is made up of anhydroxylitol (24 - 34%), xylitylglucoside (35 - 50%), and xylitol (5 - 15%).
According to a manufacturer, Aquaxyl is known for a 3-D hydration concept and an anti-dehydration shield to reinforce the outer layer of skin.
This ingredient is often derived from plants such as wood and sugarcane.
Learn more about AnhydroxylitolCitric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
In skincare formulas, citric acid can:
While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
Read more about some other popular AHA's here:
Learn more about Citric AcidGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinPentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:
Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.
On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.
Typical use levels in a formula run about 1-5%.
Learn more about Pentylene GlycolPropanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Learn more about PropanediolSerine is a non-essential amino acid (your body makes it on its own!). It is a major player in your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
Serine is one of your NMF's most abundant components that works as a skin-identical humectant. Its hydroxyl group grabs onto water molecules to boost hydration without any heaviness or occlusion.
Research on a hydrogel with serine confirmed this serine got delivered to your stratum corneum and demonstrated enhanced skin moisturization.
Interestingly serine also helps your skin produce filaggrin, a protein that keeps your skin barrier strong and used to create collagen.
Learn more about SerineSodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Learn more about Sodium HyaluronateSodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Learn more about Sodium HydroxideTrehalose is a disaccharide made of two glucose molecules (glucose is sugar!). Trehalose is used to help moisturize skin. It also has antioxidant properties.
As a humectant, trehalose helps draw moisture from the air to your skin. This helps keep your skin hydrated.
Due to its antioxidant properties, trehalose may help with signs of aging. Antioxidants help fight free-radical molecules, unstable molecules that may damage your skin.
In medicine, trehalose and hyaluronic acid are used to help treat dry eyes.
Some animals, plants, and bacteria create trehalose as a source of energy to survive freeze or lack of water.
Learn more about TrehaloseUrea is also called carbamide and is the diamide of carbonic acid. In cosmetics, urea is used to hydrate the skin. It also provides exfoliation in higher concentrations.
As a humectant, urea helps draw moisture from the air and from deep within the skin. This helps hydrate your skin. Studies show urea is an effective moisturizer for dry skin conditions. 40% urea is typical in medications for treating eczema and other skin conditions.
Urea has the strongest exfoliation effect in concentrations higher than 10%. It is a keratolytic agent, meaning it breaks down the keratin protein in the top layer of skin. This helps remove dead skin cells and flaking skin.
In medicine, urea has been shown to help increase the potency of other ingredients, such as fungal treatments.
Humans and animals use urea to metabolize nitrogen-containing compounds. Urea is highly soluble in water. Once dissolved, it is neither acidic nor alkaline.
Urea is actually one of the more well-studied and well-supported ingredients out there if you have eczema.
Clinical trials have shown that urea creams in the 5 - 10% range can:
Higher concentrations (20 -30%) can also help with thickened, scaly patches but is also more likely to sting on active flares.
Skip urea if you have rosacea. The AAD (American Academy of Dermatology) lists it alongside alcohol, menthol, and fragrance as a potential irritant for rosacea-prone skin. Urea's keratolytic and penetration-enhancing properties can trigger stinging, burning, and redness.
As always, your skin is unique, so definitely check in with your dermatologist.
Learn more about UreaWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterXylitol is a humectant and prebiotic. It can help with dry skin.
In studies, xylitol has been shown to improve dry skin. It decreased transepidermal water loss, or when water passes through the skin and evaporates. Xylitol also showed to help improve the biomechanical properties of the skin barrier.
The prebiotic property of xylitol may also help reinforce our skin's natural microbiome. Having a healthy microbiome prevents infection by bad bacteria and helps with hydration.
As a humectant, Xylitol helps draw moisture from both the air and from deeper skin layers. This helps keep skin hydrated.
Xylitol is a sugar alcohol and commonly used as a sugar substitute. It is naturally occurring in plants such as strawberries and pumpkin.
Learn more about XylitolXylitylglucoside is created from xylitol and glucose, two humectants.
Not surprisingly, this ingredient is also a humectant. It attracts and holds water in your skin, helping to maintain hydration.
This ingredient is most commonly found in a popular trio called Aquaxyl. Aquaxyl is made up of anhydroxylitol(24 - 34%), xylitylglucoside (35 - 50%), and xylitol (5 - 15%).
According to a manufacturer, Aquaxyl is known for a 3-D hydration concept and an anti-dehydration shield to reinforce the outer layer of skin.
Learn more about Xylitylglucoside