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Bioderma Sensibio Defensive Serum Versus Estée Lauder Advanced Night Repair Synchronized Multi-Recovery Complex Serum

Serum
Serum
French Brand France
American Brand United States

Updated on September 18, 2023

Overview

What they are

These products are both reef safe serums. They have a total of 6 ingredients in common

Cool Features

They both contain hyaluronic acid, peptides and Vitamin E

Suited For

They're both likely to be good for dry skin and brightening skin

Free From

They both do not contain any harsh alcohols, common allergens, parabens, silicones or sulfates

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

At a glance

Click on any of the items below to learn more

Notable Ingredients

Benefits

Concerns

Notable Ingredients

Benefits

Ingredients Side-by-side

found in both products
Sensibio Defensive Serum
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Butylene Glycol Humectant, Masking, Skin Conditioning
1 / 0

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

1 Com. / 0 Irr.
C15-19 Alkane Solvent

C15-19 alkane is a mixture of alkanes. Alkanes are hydrocarbons with carbon atoms held together by single bonds.

Unknown Full details ->
Squalane Emollient, Skin Conditioning
1 / 0 Helps hydrate Dry Skin Icon
Helps hydrate Dry SkinHelps hydrate Dry Skin Icon

Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.

1 Com. / 0 Irr.
Cellulose Absorbent

Cellulose is the main component of plant cell walls. It is used as an emulsifier, absorbent, and texture enhancer.

C20-22 Alkyl Phosphate Emulsifying

We don't have a description for C20-22 Alkyl Phosphate.

Unknown Full details ->
C20-22 Alcohols Emulsion Stabilising

We don't have a description for C20-22 Alcohols.

Unknown Full details ->
Pentylene Glycol Skin Conditioning, Solvent

Pentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.

1,2-Hexanediol Skin Conditioning, Solvent

1,2-Hexanediol is a multi-tasker ingredient. It acts as a preservative to increase shelf-life and can aid other preservatives in preventing microbe growth. 1,2-Hexanediol also helps the skin retain moisture as a humectant.

Caprylyl Glycol Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

Carnosine Skin Conditioning

We don't have a description for Carnosine.

Polyacrylate Crosspolymer-6 Emulsion Stabilising

Polyacrylate Crosspolymer-6 is a texture enhancer and pH adjuster.

Disliked Full details ->
Maltodextrin Absorbent, Emulsion Stabilising, Skin Conditioning

Maltodextrin is a polysaccharide. It is derived from starch such as rice, corn, wheat, or potato starch.

Xanthan Gum Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

Disliked Full details ->
Mannitol Humectant, Masking, Moisturising

Mannitol is a sugar alcohol. It is a humectant and moisturizes the skin. In vitro (not tested on a living organism), mannitol displays antioxidant properties.

Xylitol Humectant, Skin Conditioning

Xylitol is a humectant and prebiotic. It can help with dry skin.

Tocopherol Antioxidant, Masking, Skin Conditioning
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin IconMay cause irritation Icon
Vitamin EVitamin E Icon AntioxidantAntioxidant Icon 4 Benefits May cause irritationMay cause irritation Icon

Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.

0-3 Com. / 0-3 Irr.
Salvia Miltiorrhiza Root Extract Skin Conditioning

We don't have a description for Salvia Miltiorrhiza Root Extract.

Unknown Full details ->
Rhamnose Humectant, Masking

We don't have a description for Rhamnose.

Biosaccharide Gum-1 Skin Conditioning

Biosaccharide Gum-1 is a sugar created from fermented sorbitol. Most sorbitol is made from potato starch.

Citric Acid Buffering, Masking
AHA IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconHelps brighten skin IconMay cause irritation IconMay worsen Rosacea Icon
AHAAHA Icon 4 Benefits 2 Concerns

Citric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).

Disliked Full details ->
Glycine Soja Oil Emollient, Skin Conditioning
3 / 0 Oil IconNot safe for Fungal Acne Icon
OilOil Icon Not safe for Fungal AcneNot safe for Fungal Acne Icon

Glycine Soja Oil comes from the soybean. Glycine Soja is native to eastern Asia.

3 Com. / 0 Irr.
Very Disliked Full details ->
Hydrolyzed Hyaluronic Acid Humectant, Skin Conditioning
Hyaluronic Acid Icon
Hyaluronic AcidHyaluronic Acid Icon

Hydrolyzed Hyaluronic Acid is a form of hyaluronic acid. It is created by the hydrolysis of hyaluronic acid with a high molecular weight. Once created, Hydrolyzed Hyaluronic Acid has a low molecular weight.

Sodium Hydroxide Buffering

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

Palmitoyl Tetrapeptide-10 Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon
PeptidePeptide Icon Not safe for Fungal AcneNot safe for Fungal Acne Icon

Palmitoyl Tetrapeptide-10 isn't fungal acne safe and is a peptide.

Advanced Night Repair Synchronized Multi-Recovery Complex Serum
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Bifida Ferment Lysate Skin Conditioning
Helps hydrate Dry Skin Icon
Helps hydrate Dry SkinHelps hydrate Dry Skin Icon

Bifida Ferment Lysate is derived from the fermentation of Bifida bacteria (often with dairy). It is a probiotic and helps to strengthen our skin's microbiome.

Peg-8 Humectant, Solvent

PEG-8 is a synthetic polymer used as a humectant and solvent.

Very Disliked Full details ->
Propanediol Solvent

Propanediol helps absorb ingredients into your skin, boosting their benefits. It can act as an emollient, making your skin softer. Propanediol can help products last longer by boosting the properties of preservatives within the formulation.

Bis-Peg-18 Methyl Ether Dimethyl Silane Emollient, Humectant, Skin Conditioning

Bis-Peg-18 Methyl Ether Dimethyl Silane belongs to the siloxanes and silicones classes. It is synthetically created and has a waxy composition.

Disliked Full details ->
Methyl Gluceth-20 Humectant, Moisturising

Methyl Gluceth-20 is a humectant. Humectants help draw moisture from the air to your skin.

Glycereth-26 Humectant
0 / 0

Glycereth-26 is a synthetic ingredient and polyethylene glycol ether of Glycerin. Glycerin is already naturally found in your skin and helps keep your skin moisturized.

0 Com. / 0 Irr.
Peg-75 Humectant, Solvent

We don't have a description for Peg-75.

Unknown Full details ->
Butylene Glycol Humectant, Masking, Skin Conditioning
1 / 0

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

1 Com. / 0 Irr.
Adansonia Digitata Seed Extract Skin Conditioning

We don't have a description for Adansonia Digitata Seed Extract.

Tripeptide-32 Skin Conditioning
Peptide Icon
PeptidePeptide Icon

Tripeptide-32 is made up of amino acids proline, serine, and threonine. Amino acids are used by the skin to create proteins and a healthy skin barrier.

Sodium Hyaluronate Humectant, Skin Conditioning
0 / 0 Hyaluronic Acid Icon
Hyaluronic AcidHyaluronic Acid Icon

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

0 Com. / 0 Irr.
Yeast Extract Skin Conditioning, Skin Protecting

We don't have a description for Yeast Extract.

Lactobacillus Ferment Skin Conditioning

Lactobacillus Ferment is created by fermenting the Lactobacillus bacteria. It helps keep our skin's natural barrier and microbiome healthy.

Cola Acuminata Seed Extract Skin Conditioning

We don't have a description for Cola Acuminata Seed Extract.

Unknown Full details ->
Anthemis Nobilis Flower Extract Masking, Perfuming, Skin Conditioning
Fragrance Icon
FragranceFragrance Icon

Anthemis Nobilis Flower Extract is from the Roman Chamomile flower.

Hydrolyzed Algin

We don't have a description for Hydrolyzed Algin.

Pantethine Emollient

We don't have a description for Pantethine.

Unknown Full details ->
Caffeine Skin Conditioning

Caffeine is most associated with coffee, tea, and cacao. In skincare, it helps with calming inflammation and anti-aging.

Lecithin Emollient, Emulsifying, Skin Conditioning

Lecithin is a term for a group of substances found in plants, animals, and humans. They are made up of mixture of fatty acids. These fatty acids usually are a mixture of phosphoric acid's choline ester connected to stearic, oleic, and palmitic acids. Most lecithins are created from plant ingredients scuh as sunflower.

Disliked Full details ->
Sodium Rna Skin Conditioning

We don't have a description for Sodium Rna.

Unknown Full details ->
Bisabolol Masking, Skin Conditioning, Soothing
Helps reduce irritation Icon
Helps reduce irritationHelps reduce irritation Icon

Bisabolol is pimarily used to add fragrance to a product. However, it is also famous for helping soothe skin.

Squalane Emollient, Skin Conditioning
1 / 0 Helps hydrate Dry Skin Icon
Helps hydrate Dry SkinHelps hydrate Dry Skin Icon

Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.

1 Com. / 0 Irr.
Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Oleth-3 Phosphate
2 / 2

Oleth-3 Phosphate is created from phosphoric acid and Oleth-3.

2 Com. / 2 Irr.
Unknown Full details ->
Caprylyl Glycol Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

Oleth-3 Emulsifying
5 / 2

Oleth-3 comes from oleyl alcohol. It is an emulsifier that helps reduce surface tension of dirt and pollutants to be washed away.

5 Com. / 2 Irr.
Unknown Full details ->
Oleth-5 Emulsifying
3 / 0

Oleth-5 comes from oleyl alcohol. It is an emulsifier that helps reduce surface tension of dirt and pollutants to be washed away.

3 Com. / 0 Irr.
Unknown Full details ->
Choleth-24 Emulsifying
0 / 0

Choleth-24 comes from the cholesterol of lanolins. It is used as an emulsifier, or to help stabilize other ingredients.

0 Com. / 0 Irr.
Unknown Full details ->
Hydrogenated Lecithin Emulsifying, Skin Conditioning

Hydrogenated Lecithin is created from the hydrogenation of lecithin. Hydrogenation is a chemical reaction between molecule hydrogen and another element.

Jojoba Wax Peg-120 Esters
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Jojoba Wax Peg-120 Esters isn't fungal acne safe.

Disliked Full details ->
Ceteth-24 Cleansing, Emulsifying

We don't have a description for Ceteth-24.

Unknown Full details ->
Tocopheryl Acetate Antioxidant, Skin Conditioning
0 / 0 Vitamin E IconAntioxidant IconHelps brighten skin Icon
Vitamin EVitamin E Icon AntioxidantAntioxidant Icon Helps brighten skinHelps brighten skin Icon

Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.

0 Com. / 0 Irr.
Carbomer Emulsion Stabilising, Gel Forming
1 / 0

Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.

1 Com. / 0 Irr.
Disliked Full details ->
Triethanolamine Buffering, Emulsifying, Masking
2 / 0

Triethanolamine is an emulsifier and pH adjuster. It is created using ethylene oxide and ammonia. This gives Triethanolamine a nitrogen core and a similar scent to ammonia.

2 Com. / 0 Irr.
Very Disliked Full details ->
Tetrasodium EDTA

Tetrasodium EDTA is the salt formed from neutralizing ethylenediamine tetraacetic acid with sodium hydroxide. It is a chelating agent and used to prevent metal ions from binding to other ingredients. This helps keep the product and ingredients stable.

Disliked Full details ->
BHA Antioxidant, Masking
Antioxidant Icon
AntioxidantAntioxidant Icon

This BHA stands for butylated hydroxyanisole. If you are looking for the beta-hydroxy acid, aka as Salicylic Acid, click here.

Xanthan Gum Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

Disliked Full details ->
Potassium Sorbate Preservative
Preservative Icon
PreservativePreservative Icon

Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.

Disliked Full details ->
Disodium EDTA

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

Disliked Full details ->
Phenoxyethanol Preservative
Preservative Icon
PreservativePreservative Icon

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

Very Disliked Full details ->
CI 14700 Cosmetic Colorant
2 / 1

Ci 14700 is a synthetic red dye.

2 Com. / 1 Irr.
Unknown Full details ->
Yellow 11 Cosmetic Colorant

We don't have a description for Yellow 11.

Unknown Full details ->

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent
Loved

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Humectant, Skin Conditioning, Skin Protecting
Loved

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Humectant, Masking, Skin Conditioning
Mixed

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

  • It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
  • It is a humectant, which means that it helps attract moisture into the skin.
  • It helps improve product application.

Overall, Butylene Glycol is a safe and well-rounded ingredient. It is unlikely to irritate skin, and works well with pretty much all other ingredients.

Emollient, Skin Conditioning
Loved

Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.

Because squalane boosts hydration in the skin, it also comes with plenty of benefits: it is an antioxidant and can help fight free radicals and skin damage. Squalane is also found to have a detoxifying effect when applied.

Squalane comes from squalene, which occurs naturally within the sebum of our skin. It is one of the oils our skin produces to keep itself hydrated. Squalane is the hydrogenated version of squalene and has a longer shelf life.

Research shows that squalane is non-irritating (even at 100% concentration).

In general, it's a fantastic ingredient. It does a great job at hydrating the skin, and it's suitable for those with sensitive skin.

The source of squalane may impact malassezia / fungal acne. This is because olive oil derived squalane can contain impurities such as fatty acids and plant waxes. Sugarcane derived squalane is recommended for anyone with malassezia concerns.

Is squalane vegan?

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Learn more about Squalane
Emollient, Humectant, Skin Conditioning
Liked

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.

Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.

This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.

Learn more about Caprylyl Glycol
Emulsifying, Emulsion Stabilising, Gel Forming
Disliked

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Learn more about Xanthan Gum

Ingredient Ratings

Here's what our community thinks of the ingredients in these products.

Sensibio Defensive Serum
14
4
4
4
liked
mixed
disliked
not rated
Advanced Night Repair Synchronized Multi-Recovery Complex Serum
17
4
11
11
liked
mixed
disliked
not rated

When to use

17 Routines
59% use in am
41% use in pm
94% use every day
319 Routines
18% use in am
82% use in pm
90% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

Bioderma Sensibio Defensive Serum 26 ingredients

Sensibio Defensive Serum hasn't been rated yet.
Rate it now

Estée Lauder Advanced Night Repair Synchronized Multi-Recovery Complex Serum 43 ingredients

4.6 /5
from 5 ratings
Expensive (2) Hydrating (1) Light Scent (1)
NSmith's avatar

NSmith

5 months ago · Combination Skin
Review

Received a sample with purchase at Ulta. The serum feels nice, but ultimately is not worth the money. There are other products that can do the same...

Received a sample with purchase at Ulta. The serum feels nice, but ultimately is not worth the money. There are other products that can do the same for less.

rodney's avatar

rodney

3 months ago · Dry Skin
Review

helps so much with dryness from tretinoin + very hydrating