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Advanced Clinicals Hyaluronic Acid Hydrating Face Serum Versus SkinMedica TNS® Advanced+ Serum

Serum
Serum
American Brand United States
American Brand United States

Overview

What they are

These products are both reef safe serums. They have a total of 9 ingredients in common

Cool Features

They both contain Vitamin E

Suited For

They're both likely to be good for dry skin and brightening skin

Free From

They both do not contain any harsh alcohols, common allergens, oils, parabens or sulfates

What's Inside

They both contain silicones

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

Free from

Safety & Ethics

American Brand

Brand country of origin

Free from

Safety & Ethics

American Brand

Brand country of origin

At a glance

Click on any of the items below to learn more

Ingredients, at a glance

What's in this product, and how it might affect your skin.

Notable Ingredients

Benefits

Concerns

Ingredients, at a glance

What's in this product, and how it might affect your skin.

Notable Ingredients

Benefits

Ingredients Side-by-side

found in both products
Hyaluronic Acid Hydrating Face Serum
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

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Ethoxydiglycol Humectant, Solvent
0 / 0

Ethoxydiglycol is a synthetic solvent.

0 Com. / 0 Irr.
Mixed reviews
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Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Loved by users
2 Benefits
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Pyrus Malus Fruit Extract Skin Conditioning

Pyrus Malus Fruit Extract is extract from Apples. Apples are rich in Vitamin C, sugars, and antioxidants.

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PEG-12 Dimethicone Skin Conditioning
Silicon Icon

PEG-12 Dimethicone is a type of silicone.

Very disliked
SiliconSilicon Icon
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Aloe Barbadensis Leaf Juice Skin Conditioning
Helps reduce Skin Redness IconHelps reduce irritation Icon

Aloe Barbadensis Leaf Juice comes from leaves of the aloe plant. Aloe Barbadensis Leaf Juice is best known for helping to soothe sunburns. It is also anti-inflammatory, moisturizing, antiseptic, and can help heal wounds.

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2 Benefits
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Chondrus Crispus Extract Skin Conditioning
Helps hydrate Dry Skin Icon

Chondrus Crispus Extract comes from a red algae native to the northern Atlantic coasts of Europe and North America. It helps hydrate the skin and is rich in antioxidants.

Mixed reviews
Helps hydrate Dry SkinHelps hydrate Dry Skin Icon
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Sodium Hyaluronate Humectant, Skin Conditioning
0 / 0 Hyaluronic Acid Icon

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

0 Com. / 0 Irr.
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Hyaluronic AcidHyaluronic Acid Icon
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Sodium Carboxymethyl Beta-Glucan Cleansing

We don't have a description for Sodium Carboxymethyl Beta-Glucan yet.

Not enough ratings
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Camellia Sinensis Leaf Extract Antimicrobial, Antioxidant, Astringent
Antioxidant IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging Icon

Camellia Sinensis Leaf Extract is derived from the leaves of the tea plant. Black tea, green tea, and oolong tea are all harvested from this plant.

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AntioxidantAntioxidant Icon4 Benefits
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Epilobium Angustifolium Flower/Leaf/Stem Extract Skin Conditioning

We don't have a description for Epilobium Angustifolium Flower/Leaf/Stem Extract yet.

Not enough ratings
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Tocopheryl Acetate Antioxidant, Skin Conditioning
0 / 0 Vitamin E IconAntioxidant Icon

Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.

0 Com. / 0 Irr.
Liked by users
Vitamin EVitamin E IconAntioxidantAntioxidant Icon
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Xanthan Gum Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

Disliked by users
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Parfum Masking, Perfuming
Fragrance IconMay worsen Eczema IconMay worsen Rosacea Icon

Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.

Very disliked
FragranceFragrance Icon2 Concerns
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Phenoxyethanol Preservative
Preservative Icon

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

Very disliked
PreservativePreservative Icon
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Maltodextrin Absorbent, Emulsion Stabilising, Skin Conditioning

Maltodextrin is a polysaccharide. It is derived from starch such as rice, corn, wheat, or potato starch.

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Tetrasodium Glutamate Diacetate

Tetrasodium Glutamate Diacetate is a chelating agent. Chelating agents help prevent metal ions from binding to other ingredients. This helps prevent unwanted effects and reactions from a product. These metal ions may come from water and are found in miniscule amounts.

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Caprylyl Glycol Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

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Ethylhexylglycerin Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

Mixed reviews
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Hexylene Glycol Emulsifying, Skin Conditioning, Solvent
0-2 / 0-1

Hexylene Glycol is a surfactant. Glycols are a class of alcohols. Hexylene Glycol is a surfactant and emulsifier.

0-2 Com. / 0-1 Irr.
Disliked by users
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Citric Acid Buffering, Masking
AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconHelps brighten skin IconMay worsen Rosacea Icon

Citric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).

Disliked by users
AHAAHA Icon5 BenefitsMay worsen RosaceaMay worsen Rosacea Icon
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TNS® Advanced+ Serum
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Loved by users
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Pentylene Glycol Skin Conditioning, Solvent

Pentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.

Mixed reviews
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Human Neonatal Fibroblast Conditioned Media Skin Conditioning

This is a growth factor ingredient. Growth factors stimulate cell growth and healing.

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Glycereth-7 Triacetate Emollient, Solvent

We don't have a description for Glycereth-7 Triacetate yet.

Not enough ratings
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Shea Butter Ethyl Esters Emollient, Skin Conditioning
Not safe for Fungal Acne Icon

Shea Butter Ethyl Esters is created from, as you might have guessed, shea butter.

Disliked by users
Not safe for Fungal AcneNot safe for Fungal Acne Icon
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Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Loved by users
2 Benefits
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Ethoxydiglycol Humectant, Solvent
0 / 0

Ethoxydiglycol is a synthetic solvent.

0 Com. / 0 Irr.
Mixed reviews
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Lactococcus Ferment Lysate Skin Conditioning

Lactococcus Ferment Lysate is a postbiotic created by fermenting Lactoccus lactis, a type of bacteria more commonly used to create Lactic acid.

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Whey Protein Skin Conditioning

We don't have a description for Whey Protein yet.

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Chlorella Vulgaris Extract Skin Conditioning

Chlorella Vulgaris Extract comes from a green microalga. It is hydrating and contains antioxidants.

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Saccharide Isomerate Humectant

Saccharide Isomerate comes from sugars found in corn. It is a skin hydrator.

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Trifluoroacetyl Tripeptide-2 Skin Conditioning, Skin Protecting
Peptide Icon

Trifluoroacetyl Tripeptide-2 is a peptide.

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PeptidePeptide Icon
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Dimer Tripeptide-43
Peptide Icon

Dimer Tripeptide-43 is a peptide.

Not enough ratings
PeptidePeptide Icon
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Hydrolyzed Linseed Extract Skin Conditioning

We don't have a description for Hydrolyzed Linseed Extract yet.

Not enough ratings
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Vitis Vinifera Flower Cell Extract Masking, Skin Protecting

We don't have a description for Vitis Vinifera Flower Cell Extract yet.

Not enough ratings
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Pyrus Malus Fruit Extract Skin Conditioning

Pyrus Malus Fruit Extract is extract from Apples. Apples are rich in Vitamin C, sugars, and antioxidants.

Liked by users
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Hydroxyacetophenone Antioxidant
Antioxidant Icon

Hydroxyacetophenone is antioxidant and helps with skin conditioning.

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AntioxidantAntioxidant Icon
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Tocopheryl Acetate Antioxidant, Skin Conditioning
0 / 0 Vitamin E IconAntioxidant Icon

Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.

0 Com. / 0 Irr.
Liked by users
Vitamin EVitamin E IconAntioxidantAntioxidant Icon
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Propanediol Solvent

Propanediol helps absorb ingredients into your skin, boosting their benefits. It can act as an emollient, making your skin softer. Propanediol can help products last longer by boosting the properties of preservatives within the formulation.

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Xanthan Gum Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

Disliked by users
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Polyacrylate Crosspolymer-6 Emulsion Stabilising

Polyacrylate Crosspolymer-6 is a texture enhancer and pH adjuster.

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Polyacrylate-13

Polyacrylate-13 is a type of acrylate polymer. Acrylate polymers are commonly used as adhesives in cosmetics.

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Polyisobutene

Polyisobutene is a synthetic polymer made from isobutene.

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Sclerotium Gum Emulsion Stabilising, Skin Conditioning

Sclerotium Gum is a polysaccharide gum made by the fungus, Sclerotium rolfssii. It is similar to xanthan gum.

Mixed reviews
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PEG-12 Dimethicone Skin Conditioning
Silicon Icon

PEG-12 Dimethicone is a type of silicone.

Very disliked
SiliconSilicon Icon
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Lecithin Emollient, Emulsifying, Skin Conditioning

Lecithin is a term for a group of substances found in plants, animals, and humans. They are made up of mixture of fatty acids.

Mixed reviews
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Pullulan

Pullulan is a low viscosity polysaccharide (a long chain carbohydrate) with binding and film forming properties when dissolved in water. It is used to create a "silicone-like" or silky feel in cosmetics without adding viscosity.

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Butylene Glycol Humectant, Masking, Skin Conditioning
1 / 0 Helps hydrate Dry Skin Icon

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

1 Com. / 0 Irr.
Mixed reviews
Helps hydrate Dry SkinHelps hydrate Dry Skin Icon
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Sodium Citrate Buffering, Masking

Sodium Citrate is the sodium salts of citric acid. In skincare, it is used to alter pH levels and acts as a preservative.

Mixed reviews
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Polysorbate 20 Emulsifying
0 / 0 Not safe for Fungal Acne Icon

Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.

0 Com. / 0 Irr.
Very disliked
Not safe for Fungal AcneNot safe for Fungal Acne Icon
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Aminomethyl Propanol Buffering

Aminomethyl Propanol is used to adjust the pH of products. It is also used as a base to create other organic compounds. Having a balanced pH is important for protecting your skin.

Mixed reviews
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Dextran

We don't have a description for Dextran yet.

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Disodium EDTA

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

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Phenoxyethanol Preservative
Preservative Icon

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

Very disliked
PreservativePreservative Icon
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Ethylhexylglycerin Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

Mixed reviews
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Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent
Loved

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Humectant, Solvent
Mixed

Ethoxydiglycol is a synthetic solvent.

Solvents are used to keep ingredients together in a product. They can help dissolve ingredients to stable bases or help evenly distribute ingredients throughout the product.

Ethoxydiglycol also helps deliver other key ingredients into the skin.

Learn more about Ethoxydiglycol
Humectant, Skin Conditioning, Skin Protecting
Loved

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Skin Conditioning
Liked

Pyrus Malus Fruit Extract is extract from Apples. Apples are rich in Vitamin C, sugars, and antioxidants.

The sugar in Apples are humectants and help hydrate the skin. On top of that, apples also contain some acids, such as malic acid. These acids may have a mild exfoliating effect.

Last, the phytochemicals found in apples are strong antioxidants. These antioxidants help with anti-aging as they protect your skin cells against oxidative damage.

Learn more about Pyrus Malus Fruit Extract
Skin Conditioning
Very Disliked

PEG-12 Dimethicone is a type of silicone.

Antioxidant, Skin Conditioning
Liked

Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.

One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.

Tocopheryl Acetate is commonly found in both skincare and dietary supplements.

Learn more about Tocopheryl Acetate
Emulsifying, Emulsion Stabilising, Gel Forming
Disliked

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Learn more about Xanthan Gum
Preservative
Very Disliked

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

Skin Conditioning
Mixed

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.

When to use

29 Routines
59% use in am
41% use in pm
93% use every day
When to use See routines that use it ->
118 Routines
48% use in am
52% use in pm
96% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

Advanced Clinicals Hyaluronic Acid Hydrating Face Serum 21 ingredients

4.0 /5
from 2 ratings
Absorbs Well (2) Great Value (1) Hydrating (1)
Noone's avatar

Noone

1 year ago · Oily Skin
Review

Acid is good, the price is accessible. Improves the visibility of the skin. Does not make the skin oily. Leaves the skin moist.

SSBB's avatar

S B

2 months ago · Combination Skin
Review

week 2:
I think I love herrr. smells like fruit loops and doesn't sting at all. helps soften my dry skin

OG:
Works pretty well so far!

SkinMedica TNS® Advanced+ Serum 35 ingredients

5.0 /5
from 1 rating
Srr1111's avatar

Srr1111

1 year ago · Dry Skin
Review

Keeps my skin youthful