Superdrug Vitamin E Moisture Boost Facial Serum

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

This ingredient is considered a modified starch. Starch can also be found naturally in plants.

One study from 1991 found that 5% of this ingredient enhanced titanium dioxide SPF by as much as 40%. The study found 1% titanium dioxide had a 5.6 SPF and adding 5% of aluminum starch octenylsuccinate boosted it to an SPF of 8.1

Although “aluminum” in an ingredient name can raise red flags for some consumers, the form and usage context matter significantly. For typical topical applications, there is no substantial evidence of health risks - such as cancer, neurotoxicity, or systemic “aluminum overload.”

It should be noted the precursor to Polyacrylamide is acrylamide. Acrylamide is a carcinogen. Most reputable sources of Polyacrylamide will screen for residual acrylamide to make sure the count is in a safe range. Acrylamide is not able to be absorbed through the skin.

We recommend speaking with a professional if you have concerns.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Two things floating around online that cause fear-mongering:

There's one scary-sounding study related to kidney tumors in male rats; this depends on a protein called alpha-2u-globulin that binds the ingredient and clogs up kidney cells. Female rats barely make this protein, and humans don't make it at all so this effect cannot happen to us. Regulatory bodies have states this rat-only pathway shouldn't be used to judge human risk.

The other thing you'll see is 1,4-dioxane being a trace byproduct that can form during manufacturing of petroleum-derived ingredients. This is a real, but heavily managed/monitored issue. This byproduct is removed through purification steps before the ingredients goes into the formula. Regulatory bodies also actively monitor residual levels for safety.

One last thing to note: this ingredient is a pure hydrocarbon with no fatty-acid or ester chains for Malassezia to feed on, so it's considered fungal acne safe.

Some studies suggest betaine may support making skin tone more even.

Fun fact: Betaine naturally exists in the skin and the body. In cosmetic products, it can be either plant-derived (most commonly from sugar beets) or synthetically produced for consistency and stability.

Betaine is also known as trimethylglycine.

For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.

The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.

For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.

One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.

Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.

Parfum can also be used to mask or cover an unpleasant scent.

The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.

Tocopheryl Acetate is commonly found in both skincare and dietary supplements.

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Vaccinium Myrtillus Fruit Extract also helps reduce irritation.

This ingredient gets a bad rep because it is irritating and drying due to its astringent property. Astringents draw out natural oils in tissue to constrict pores and dry out your skin.

However, alcohol denat. is not all that bad.

Due to its low molecular weight, alcohol denat. tends to evaporate quickly. One study on pig skin found half of applied alcohol evaporated in 10 seconds and less than 3% stayed on skin.

This also helps other ingredients become better absorbed upon application.

Studies are conflicted about whether this ingredient causes skin dehydration. One study from 2005 found adding emollients to propanol-based sanitizer decreased skin dryness and irritation. Another study found irritation only occurs if your skin is already damaged.

Small amounts of alcohol are generally tolerated by oily skin or people who live in humid environments.

The rule of thumb is this ingredient will probably not affect your skin much if it is near the end of an ingredients list.

One thing to note:
People with ALDH2 (aldehyde dehydrogenase 2) deficiency may experience skin irritation from continued alcohol use. About 8% of the world's population have this deficiency.

The Cosmetic Ingredient Review Expert Panel has determined denatured alcohols to be safe for use in concentrations between 0.05% and 12% (depending on which denaturant is used).

Also...

This ingredient has antimicrobial and solvent properties.

The antimicrobial property helps preserve products and increase their shelf life. As a solvent, it helps dissolve other ingredients.

Look for formulas that contain glycerin, hyaluronic acid, or panthenol if you want to offset any drying effect.

This ingredient will trip away your skin's natural oils/lipids that help it lock in moisture. This can worsen dryness, trigger eczema flare-ups, and aggravate rosacea.

Be sure to patch test any product with this ingredient if you have dry or sensitive skin, eczema, or rosacea.

Lauroyl lysine is barely soluble in water.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Glycolic acid is a derivative of sugarcane. While glycolic acid is an AHA with exfoliating properties, sugarcane is not an AHA.

A study from 2021 found the compounds in sugarcane extract to have antioxidant, antimicrobial, and anti-inflammatory activity. The study also suggests these compounds can inhibit skin ageing enzymes and promote collagen synthesis.

Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.

"Alkaline" refers to a high pH level. A low pH level would be considered acidic.

It can also be mildly exfoliating due to the citric acid, an AHA.

Citrus fruits are rich in flavonoids, alkaloids, and vitamin C.

And of course, lemons are rich in Vitamin C. Vitamin C helps with skin-brightening and increasing collagen production.

The acidity of lemons may work as an astringent for acne.

However, lemons can also cause skin sensitivity due to its limonene content. It can also increase photosensitivity, or sensitivity to the sun.

This ingredient is also used to add a lemon scent to products.

The common safety discussion around this ingredient involves a manufacturing byproduct called 1,4-dioxane.

Trace amounts can form during production but the EU's Scientific Committee on Consumer Safety has concluded that levels at/below 10 ppm in finished products are safe (commercial products consistently fall within acceptable margins).

True allergic reactions are uncommon and the CIR Expert Panel has confirmed this ingredient to be safe as used in cosmetics.

Because it is derived from lauric acid, it may not be fungal acne safe.

Our bodies use Calcium Pantothenate for various metabolic functinos. These functions include metabolizing carbohydrates, proteins, and fatty acids.

Keratinocytes make up the majority of the outermost layer of skin. These cells protect our skin from UV exposure, infection, and help keep skin hydrated.

This ingredient is also considered a humectant. Humectants help hydrate the skin by drawing moisture to it.

Your body uses linoleic acid to build ceramides and prostaglandins. Ceramides keep your skin's barrier hydrated and strong while prosaglandins help control inflammation and healing.

Needless to say, linoleic acid is crucial for having a strong skin barrier.

One study found applying linoleic acid rich sunflower oil to be more effective at repairing the skin barrier than olive oil.

This ingredient can also help treat acne by softening sebum to prevent clogged pores. Another study found using 2.5% linoleic acid gel for 4 weeks showed a 25% reduction in small comedones.

Studies show it can also help lighten hyperpigmentation or sun spots by disrupting the melanin production process. It also helps your skin shed melanin pigment from your skin caused by UV exposure.

Due to its role in the production of the fatty acid prostaglandin, linoleic acid can also help reduce inflammation and support wound healing.

Fun fact: Linoleic acid is an essential fatty acid. This means our bodies cannot create it on its own and we need to get it through foods such as nuts and vegetable oils.

Just know this ingredient is not always fungal-acne safe because it is a long-chain fatty acid (with 18 carbon atoms) that directly feeds the Malassezia yeast responsible for fungal acne.

First, Retinyl palmitate is created from palmitic acid and retinol. It is a retinol ester and considered one of the weaker forms of retinoid.

This is because all retinoids have to be converted to Tretinoin, AKA retinoic acid. Retinyl Palmitate is pretty far down the line and has to go through multiple conversions before its effects are seen.

Due to this long and ineffective conversion line, the benefits of Retinyl Palmitate are debated.

Studies show Retinyl Palmitate to help:

Dermatologists say this ingredient is ineffective because it isn't used in high enough concentrations in cosmetics.

This ingredient used to be found in sunscreens to boost the efficacy of sunscreen filters.

The downfall of Retinyl Palmitate was due to released reports about the ingredient being correlated to sun damage and skin tumors.

While there is a study showing this ingredient to cause DNA damage when exposed to UV-A, there is no concrete proof of it being linked to skin cancer. It is safe to use when used correctly.

All retinoids increase your skin's sensitivity to the sun in the first few months of usage. Be especially careful with reapplying sunscreen when using any form of retinoid.

Currently, this ingredient is still allowed in cosmetics all over the world. In Canada, cosmetics must have a warning label stating the product to contain Retinyl Palmitate

Fun fact: This ingredient is often added to low-fat milk to increase the levels of Vitamin A.

More research is needed on applying biotin topically. However, taking biotin orally has been shown to help nourish the skin, hair, and nails. They play a role in forming skin-hydrating fatty acids.

Biotin is water-soluble. It can be found in foods such as fish, eggs, dairy, nuts, and meat. Vitamin H stands for "haar" and "haut". These are the German words for hair and skin.

This ingredient has a scent that is floral, spicy tropical, and citrus-like.

In many countries, coumarin is banned as a food additive. However, it can be found in soaps, tobacco products, and some alcohol drinks.

Plants use coumarins as a chemical defense. Some plants that have coumarins include lavender, tonka beans, and yellow clovers.

Naturally occurring Alpha-Isomethyl Ionone may be found in Saccharomyces cerevisiae, or the yeast used to make wine and bread.

The term 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term. For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance.