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Perricone MD High Potency Hyaluronic Intensive Hydrating Serum Ingredients Explained

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Published on January 21, 2023 Submitted by Susana_Iglesias

Overview

What it is

Serum with 38 ingredients that contains AHA, ceramides, exfoliants, hyaluronic acid, niacinamide and peptides

Cool Features

It is cruelty-free and reef safe

Suited For

It has ingredients that are good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture

Free From

It doesn't contain any harsh alcohols, common allergens, fragrances, oils or parabens

Fun facts

Perricone MD is from United States. This product is used in 9 routines created by our community.

We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.

You should know

Here's our breakdown of the notable ingredients, benefits, and concerns we determined from the ingredients in this product. Click any item to learn more.

Notable Ingredients

AHA
Exfoliators
Niacinamide
Ceramides
Hyaluronic Acid (4)
Peptides (2)

Benefits

Hydrating (2)
Good For Oily Skin
Redness Reducing (2)
Reduces Irritation
Skin Texture (2)
Reduces Large Pores (2)
Anti-Aging (2)
Dark Spots
Scar Healing (2)
Acne Fighting
Brightening (4)

Concerns

Acne Trigger
Irritating (2)
Rosacea (2)
Eczema

Ingredient Info

Click any item below to learn more and view relevant ingredients.
alcohol-free
silicon-free
fragrance-free
sulfate-free
paraben-free
oil-free
fungal-acne safe
reef-safe
eu-allergen-free
vegan
cruelty-free

Ingredients Overview

Here's our quick-to-read summary of the ingredients in this product. Keep scrolling if you'd like to learn more about what each ingredient does!
Ingredient
Features
1
Skin Conditioning, Solvent
2
Emollient, Skin Conditioning, Skin Protecting
1 / 0
Silicon Icon
3
Humectant, Masking, Skin Conditioning, Solvent
1 / 0
4
Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconGood for Minimizing Pores IconGood for Dark Spots IconHelps fight Acne IconHelps brighten skin Icon
5
Skin Conditioning
6
Emollient, Skin Conditioning
1 / 0
Helps hydrate Dry Skin Icon
7
Emulsion Stabilising
8
9
Not safe for Fungal Acne Icon
10
11
12
Emulsifying
Not safe for Fungal Acne Icon
13
Solvent
14
Emulsifying
0 / 0
Not safe for Fungal Acne Icon
15
Skin Conditioning, Solvent
16
Emollient, Humectant, Skin Conditioning
17
Buffering
18
Antioxidant
Antioxidant Icon
19
Buffering, Masking
AHA IconMay cause irritation IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconMay worsen Rosacea IconHelps brighten skin Icon
20
Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconHelps with Anti-Aging Icon
21
Cleansing, Foaming
22
Emulsifying
3 / 0
Bad for Acne Prone Skin IconNot safe for Fungal Acne Icon
23
Skin Conditioning
24
Antioxidant
Antioxidant Icon
25
Abrasive, Absorbent
Exfoliant IconMay worsen Eczema IconMay worsen Rosacea Icon
26
Humectant
Hyaluronic Acid Icon
27
Humectant, Skin Conditioning
0 / 0
Hyaluronic Acid Icon
28
Preservative
Preservative Icon
29
Skin Conditioning
30
Humectant, Skin Conditioning
Hyaluronic Acid Icon
31
Humectant, Moisturising, Skin Conditioning
Hyaluronic Acid IconMay cause irritation IconGood for Skin Texture IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin Icon
32
Skin Conditioning
33
Skin Conditioning
Peptide Icon
34
Skin Conditioning
Peptide Icon
35
Humectant, Skin Conditioning, Skin Protecting, Solvent
0 / 0
Helps hydrate Dry Skin IconHelps brighten skin Icon
36
Skin Conditioning
37
Humectant, Skin Conditioning
38
Sulfate Icon

Ingredients Explained

This product contains 38 ingredients. Click on any ingredient to learn more about it
1
What it does: Skin Conditioning, Solvent
Community Rating: Loved

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. Talk about multi-purpose! If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
2
What it does: Emollient, Skin Conditioning, Skin Protecting
Community Rating: Very Disliked

Dimethicone is a silicone used for making products smooth and silky. It also has the added benefit of sealing in hydration. The amount of dimethicone found in beauty products is considered safe and non-comedogenic, meaning it won't clog pores.

Dimethicone has been found increase absorption in skin, boosting the benefits of other ingredients. While there is concern for the safety of dimethicone, the levels used in skincare are safe for use.

3
What it does: Humectant, Masking, Skin Conditioning, Solvent
Community Rating: Mixed

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

  • It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
  • It is a humectant, which means that it helps attract moisture into the skin.
  • It helps improve product application.

Overall, Butylene Glycol is a safe and well-rounded ingredient. It is unlikely to irritate skin, and works well with pretty much all other ingredients.

4
What it does: Smoothing
Community Rating: Loved

Niacinamide has emerged as an all-star ingredient due to its many benefits.

It is known to treat acne by reducing inflammation. It also helps fade dark-spots and strengthen the skin by promoting the growth of the ceramide barrier.

Other benefits include smoothing wrinkles and minimizing redness.

The cherry on top? Niacinamide can also help build keratin, a protein that keeps skin firm.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

Niacinamide can be mixed with other ingredients to boost benefits. For instance, it has shown to be effective when used with copper, folic acid, and zinc to treat acne.

Learn more about Niacinamide
5
What it does: Skin Conditioning
Community Rating: Liked

Acetyl Glucosamine is an antioxidant and humectant. It is a form of Vitamin C.

Acetyl Glucosamine helps the skin produce hyaluronic acid and boost hydration.

Antioxidants help fight off free-radicals, molecules that may damage skin cells.

When paired with niacinamide, Acetyl Glucosamine has been shown to be effective at reducing discoloration.

Read more about other types of Vitamin C:

Learn more about Acetyl Glucosamine
6
What it does: Emollient, Skin Conditioning
Community Rating: Loved

Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.

Because squalane boosts hydration in the skin, it also comes with plenty of benefits: it is an antioxidant and can help fight free radicals and skin damage. Squalane is also found to have a detoxifying effect when applied.

Squalane comes from squalene, which occurs naturally within the sebum of our skin. It is one of the oils our skin produces to keep itself hydrated. Squalane is the hydrogenated version of squalene and has a longer shelf life.

Research shows that squalane is non-irritating (even at 100% concentration).

In general, it's a fantastic ingredient. It does a great job at hydrating the skin, and it's suitable for those with sensitive skin.

The source of squalane may impact malassezia / fungal acne. This is because olive oil derived squalane can contain impurities such as fatty acids and plant waxes. Sugarcane derived squalane is recommended for anyone with malassezia concerns.

Is squalane vegan? This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Learn more about Squalane
7
What it does: Emulsion Stabilising
Community Rating: Very Disliked

This long ingredient is a copolymer of sodium acrylate and sodium acryloyldimethyl taurate monomers.

It is used to help stabilize other ingredients and create a thicker gel-like texture.

Emulsifiers prevent oils and waters from separating.

Learn more about Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
8
What it does:
Community Rating: Disliked

We don't have a description for Polysilicone-11.

9
What it does:
Community Rating: Disliked

Cetearyl Olivate is an emulsifier and texture enhancer. It is derived from the fatty acids of olive oil and Cetearyl alcohol, and is biodegradable.

As an emulsifier, it is used to prevent oils and waters from separating. It can also

Manufacturers use the name Olivem 1000. This ingredient has been found to preserve the natural microbiome of skin. Having a healthy microbiome helps keep our skin healthy and protects against harmful bacteria. This ingredient is grouped with Sorbitan Olivate under the name Olivem 1000.

Learn more about Cetearyl Olivate

We don't have a description for Hdi/Trimethylol Hexyllactone Crosspolymer.

11
What it does:
Community Rating: Very Disliked

Polyisobutene is a synthetic polymer made from isobutene.

It is a film-forming agent and helps bind ingredients together.

Polyisobutene is not absorbed by the skin.

Learn more about Polyisobutene
12
What it does: Emulsifying
Community Rating: Very Disliked

Sorbitan Olivate is created from the fatty acids in olive oil and sorbitol.

Sorbitan Olivate is an oil in water emulsifier. It helps stabilize a product by preventing oils and waters from separating. Sorbitan Olivate also helps hydrate the skin.

Manufacturers sell sorbitan olivate under the name OliveM 1000. OliveM 1000 a multifunctional ingredient. It is self-emulsifying. According to a manufacturer, OliveM 1000 does not disrupt natural skin biome.

Learn more about Sorbitan Olivate
13
What it does: Solvent
Community Rating: Disliked

Dimethyl Isosorbide is a solvent and helps deliver actives into your skin. It is created from sorbitol.

As a solvent, dimethyl isosorbide helps dissolve other ingredients. This helps ensure even distribution of an ingredient. It may also be used to decrease the thickness of a product.

Studies show dimethyl isosorbide is able to penetrate skin to deliver other ingredients into the skin, making them more effective.

Learn more about Dimethyl Isosorbide
14
What it does: Emulsifying
Community Rating: Very Disliked

Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.

As a surfactant, it helps collect dirt and oils for washing. Emulsifiers prevent oils and water from separating.

Polysorbate 20 also adds scent to a product. Since it is made using sorbitol, it has a sweet scent. Sorbitol can also be found in fruits such as apples and peaches.

The lauric acid used to create Polysorbate 20 is often derived from coconuts.

Polysorbate 20 may not be fungal acne safe.

Learn more about Polysorbate 20
15
What it does: Skin Conditioning, Solvent
Community Rating: Mixed

1,2-Hexanediol is a multi-tasker ingredient. It acts as a preservative to increase shelf-life and can aid other preservatives in preventing microbe growth. 1,2-Hexanediol also helps the skin retain moisture as a humectant.

In products that are water-based, this ingredient can help stabilize perfumes and fragrances. It can also help make the texture of products softer and more smooth.

16
What it does: Emollient, Humectant, Skin Conditioning
Community Rating: Liked

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.

Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.

This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.

Learn more about Caprylyl Glycol
17
What it does: Buffering
Community Rating: Mixed

We don't have a description for Dimethyl Mea.

18
What it does: Antioxidant
Community Rating: Liked

Hydroxyacetophenone is antioxidant and helps with skin conditioning.

Antioxidants help fight off free-radical molecules. These unstable molecules may damage your skin cells. By helping stabilize free-radicals, antioxidants may help in anti-aging.

Hydroxyacetophenone boosts the efficiency of other preservatives.

Learn more about Hydroxyacetophenone
19
What it does: Buffering, Masking
Community Rating: Disliked

Citric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).

If you spot Citric Acid near the end of an ingredient list, it's likely there as a pH adjuster rather than an active ingredient.

As an AHA, Citric Acid removes the top layer of skin cells from the newer layer of skin underneath. This helps skin to remove dark spots and look more even.

Read more about some other popular AHA's here:

Learn more about Citric Acid
20
What it does: Skin Conditioning
Community Rating: Loved

Ceramide NP is a type of ceramide.

Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. They are known for their ability to hold water and thus are a great ingredient for dry skin.

Ceramides are an important building block for our skin barrier. A stronger barrier helps the skin look more firm and hydrated. By bolstering the skin ceramides act as a barrier against irritating ingredients. This can help with inflammation as well.

If you would like to eat ceramides, sweet potatoes contain a small amount.

Read more about other common types of ceramides here: Ceramide AP Ceramide EOP

Learn more about Ceramide NP
21
What it does: Cleansing, Foaming

Caprylyl/Capryl Glucoside is an alkyl glucoside. This just means it is creating by reacting alcohol and sugar. It is a cleansing and foaming ingredient.

Caprylyl/Capryl Glucoside helps remove the dirt, oil, and other pollutants from your skin.

22
What it does: Emulsifying
Community Rating: Very Disliked

Sorbitan Oleate is created from compounds in oleic acid and sorbitol. It is used to stabilize a product by preventing ingredients from separating.

Emulsifiers help keep ingredients together, such as oils and water.

Sorbitan Oleate may not be fungal acne safe. It can also worsen oily skin.

Learn more about Sorbitan Oleate
23
What it does: Skin Conditioning

This is the synthetic salt of gluconic acid, a form of PHA and mild exfoliant.

It is mainly used to stabilize oil and butter formulations from going bad. Sodium gluconate is a humectant, pH regulator, and chelating agent.

Chelating agents help neutralize unwanted metals from affecting the formulation.

Sodium gluconate is water-soluble.

Learn more about Sodium Gluconate
24
What it does: Antioxidant

Spermidine is an antioxidant.

25
What it does: Abrasive, Absorbent
Community Rating: Disliked

Silica is a mineral naturally found in our skin. It helps to thicken and smooth the texture of a product. It also acts as an agent for other ingredients by increasing the absorption of other ingredients into the skin.

Silica is often used for absorption and can help reduce shine when products are applied. Silica occurs in naturally in materials like clay and sandstone, and it can also be produced synthetically.

Silica is present naturally within the skin during collagen production and when reducing inflammation.

Learn more about Silica
26
What it does: Humectant
Community Rating: Liked

Sodium Acetylated Hyaluronate is a type of Hyaluronic Acid.

Hyaluronic Acids help moisturize, soothe, and protect the skin.

27
What it does: Humectant, Skin Conditioning
Community Rating: Loved

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Learn more about Sodium Hyaluronate
28
What it does: Preservative
Community Rating: Very Disliked

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent germ and microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

29
What it does: Skin Conditioning
Community Rating: Liked

Phytosphingosine is a phospholipid naturally found in our skin. It helps moisturize, soothe, and protect skin.

Phytosphingosine is already present in our skin. On our skin, it is a building block for ceramides.

Phytosphingosine tells our skin to increase its natural moisturizing factor (NMF). The NMF is responsible for hydration, a strong barrier, and plasticity. Our NMF decreases with age. Increasing NMF leads to more healthy and hydrated skin.

Studies show products formulated with NMF ingredients help strengthen our skin's barrier. Having a healthy skin barrier reduces irritation and increases hydration. Our skin barrier is responsible for having plump and firm skin. It also helps protect our skin against infection, allergies, and inflammation.

Phytosphingosine is also abundant in plants and fungi.

More ingredients that help boost collagen in skin:

Learn more about Phytosphingosine
30
What it does: Humectant, Skin Conditioning
Community Rating: Liked

Sodium Hyaluronate Crosspolymer is a type of hyaluronic acid. In fact, it is modified version of hyaluronic acid.

The structure of Sodium Hyaluronate Crosspolymer allows it to stay in the skin's top layer for a longer period of time. This allows for even more hydration and humectant action than hyaluronic acid.

These are some other common types of Hyaluronic Acid:

Learn more about Sodium Hyaluronate Crosspolymer
31
What it does: Humectant, Moisturising, Skin Conditioning
Community Rating: Loved

Hyaluronic acid is naturally found in healthy skin. It is a humectant, meaning it draws moisture to your skin.

Hyaluronic Acid has the capacity to bind to large amounts of water. This ingredient helps hydrate, soothe, and protect the skin.

Fun fact: It is already naturally found in our bodies, such as the fluids of our eyes and our joints.

Studies find this ingredient to have anti-inflammatory and anti-microbial properties. This can help speed up wound-healing,

These are some other common types of Hyaluronic Acid:

Learn more about Hyaluronic Acid
32
What it does: Skin Conditioning
Community Rating: Mixed

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.

33
What it does: Skin Conditioning
Community Rating: Loved

Acetyl Tetrapeptide-11 is a peptide.

34
What it does: Skin Conditioning
Community Rating: Loved

Acetyl Tetrapeptide-9 is a peptide.

35
What it does: Humectant, Skin Conditioning, Skin Protecting, Solvent
Community Rating: Loved

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
36
What it does: Skin Conditioning

We don't have a description for Disodium Acetyl Glucosamine Phosphate.

37
What it does: Humectant, Skin Conditioning

We don't have a description for Sodium Glucuronate.

38
What it does:
Community Rating: Very Disliked

Magnesium Sulfate is a salt. It can be naturally found in sea water or mineral deposits.

In cosmetics, Magnesium Sulfate is used to thicken a product or help dilute other solids. It is a non-reactive and non-irritating ingredient.

You might recognize Magnesium Sulfate as epsom salt, or the bath salt used to help relieve muscle aches.

One study shows magnesium deficiency may lead to inflammation of the skin. Applying magnesium topically may help reduce inflammation.

Learn more about Magnesium Sulfate
Embed Ingredients

Here's what our community thinks of the 38 ingredients in this product ✨

39% are loved or liked
11% have mixed ratings
34% are disliked or very disliked
16% have no rating yet

When to use

Here's some more info on how this product is used by our community.

Directions

1. After cleansing, massage onto damp face and neck using a gentle upward motion.
2. Wait until fully absorbed and follow with your favorite moisturizer.
3. Use morning and evening.

1. After cleansing, massage onto damp face and neck using a gentle upward motion.
2. Wait until fully absorbed and follow with your favorite moisturizer.
3. Use morning and evening.

When to use

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