ZO Skin Health Daily Power Defense Versus Paula's Choice Resist Intensive Wrinkle-Repair Retinol Serum
Updated on September 14, 2023
Overview
Cool Features
They both contain retinoid and Vitamin E
Suited For
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
They both do not contain any harsh alcohols or sulfates
What's Inside
They both contain oils and silicones
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
ZO Skin Health Daily Power Defense 51 ingredients
Paula's Choice Resist Intensive Wrinkle-Repair Retinol Serum 21 ingredients
At a glance
Click on any of the items below to learn more
ZO Skin Health Daily Power Defense 51 ingredients
Paula's Choice Resist Intensive Wrinkle-Repair Retinol Serum 21 ingredients
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Concerns
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Ingredients Side-by-side
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
Cyclopentasiloxane is a silicone used to improve texture and trap moisture. An easier name for this is D5.
Cyclohexasiloxane is a type of silicone more commonly known as D6. It is an emollient and solvent.
Pentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.
3 Concerns
Cetearyl alcohol is a mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is mainly used as an emulsifier. Emulsifiers help prevent the separation of oils and products. Due to its composition, it can also be used to thicken a product or help create foam.
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
Steareth-20 is a waxy compound used to emulsify ingredients. It is created from stearyl alcohol.
Jojoba Esters is a wax created from Jojoba oil. It is an emollient and film-forming ingredient. In bead form, it is an exfoliator.
Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.
C14-22 Alcohols is made up of synthetic fatty alcohols. More specifically, these fatty alcohols contain 14 to 22 carbons in the alkyl chain.
Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
Cetearyl Glucoside is a surfactant and emulsifier. It can be produced from synthetic of natural sources of cetearyl alcohol and glucose.
Not safe for Fungal Acne
Safflower Oil/Palm Oil Aminopropanediol Esters is an oil and isn't fungal acne safe.
Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Not safe for Fungal Acne
Palmitoyl Oligopeptide is a form of peptide. It is created by blending peptides with palmitic acid. Peptides are building blocks for protein.
Not safe for Fungal Acne
Palmitoyl Tetrapeptide-7 is a peptide. Peptides are building blocks for protein.
Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.
Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
Disodium EDTA plays a role in making products more stable by aiding other preservatives.
Cellulose is the main component of plant cell walls. It is used as an emulsifier, absorbent, and texture enhancer.
Hexylene Glycol is a surfactant. Glycols are a class of alcohols. Hexylene Glycol is a surfactant and emulsifier.
Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.
Beta-Glucan is a polysaccharide. It can be derived from the cell walls of seaweed, oats, yeast, and fungi.
1,2-Hexanediol is a multi-tasker ingredient. It acts as a preservative to increase shelf-life and can aid other preservatives in preventing microbe growth. 1,2-Hexanediol also helps the skin retain moisture as a humectant.
Paraben 2 Concerns
Methylparaben is a preservative and is a paraben. It is used to prevent the growth of fungus, mold, and other harmful bacteria. Parabens are chemicals used as preservatives in both cosmetics and food.
Lecithin is a term for a group of substances found in plants, animals, and humans. They are made up of mixture of fatty acids. These fatty acids usually are a mixture of phosphoric acid's choline ester connected to stearic, oleic, and palmitic acids. Most lecithins are created from plant ingredients scuh as sunflower.
This ingredient is a semi-synthetic polymer created from cellulose. In case you need a refresher, cellulose is the main component of plant cell walls.
Sorbitol is a sugar alcohol. It is a hydrating and moisturizing agent created from the reduction process of glucose.
EDTA is the shortened name for ethylenediamine tetraacetic acid. It is a chelating agent and used to stabilize products.
May worsen Eczema
Benzoic Acid is used to preserve and adjust the pH of products.
Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.
8 Benefits 3 Concerns
Retinol is a gold-standard ingredient for anti-aging. It is a form of Vitamin A and belongs to the class of retinoids that also includes tretinoin.
7 Benefits 3 Concerns
Retinyl palmitate is a form of retinoid. Retinoids are the superstar class of anti-aging ingredients that include tretinoin and retinol.
Antioxidant Helps brighten skin
Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
Citrus Aurantium Dulcis Peel Oil is oil from the peel of an orange fruit.
Oil EU Allergen
Citrus Limon Peel Oil is created from the peels of the lemon. It is used to add a lemon-scent to products. Lemon peel oil also has antibacterial, antifungal, and antioxidant properties. However, it may also cause phototoxicity and sensitize skin.
Oil EU Allergen
Mentha Piperita Oil is the volatile oil obtained from the whole plant of the Peppermint plant.
Antioxidant 4 Benefits May cause irritation
Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.
Limonene is a fragrance that adds scent and taste to a formulation.
This pigment is called Ultramarine blue lazurite. It gives a saturated blue color, but can be used to create other colors as well.
Water, Cetearyl Isononanoate, Cyclopentasiloxane, Cyclohexasiloxane, Pentylene Glycol, Cetearyl Alcohol, Glycerin, Steareth-20, Jojoba Esters, Carbomer, C14-22 Alcohols, Phenoxyethanol, Cetearyl Glucoside, Safflower Oil/Palm Oil Aminopropanediol Esters, Polysorbate 20, Butylene Glycol, Palmitoyl Oligopeptide, Palmitoyl Tetrapeptide-7, Sodium Hydroxide, Caprylyl Glycol, C12-20 Alkyl Glucoside, Ethylhexylglycerin, Lactose, Disodium EDTA, Cellulose, Hexylene Glycol, Potassium Sorbate, Beta-Glucan, 1,2-Hexanediol, Methylparaben, Lecithin, Hydroxypropyl Methylcellulose, Sorbitol, EDTA, Benzoic Acid, Sodium Benzoate, Arabidopsis Thaliana Extract, Micrococcus Lysate, Retinol, Retinyl Palmitate, Tocopheryl Acetate, Citrus Aurantium Dulcis Peel Oil, Citrus Limon Peel Oil, Citrus Nobilis Peel Oil, Citrus Reticulata Peel Oil, Mentha Piperita Oil, Mimosa Tenuiflora Bark Extract, Tocopherol, Limonene, CI 77007, CI 60730
Cyclopentasiloxane is a silicone used to improve texture and trap moisture. An easier name for this is D5.
Dimethiconol is a silicone that resembles the popular dimethicone. Like other silicones, it is an emollient. Emollients create a thin film on skin to prevent moisture from escaping.
Dicaprylyl Carbonate comes from carbonic acid and caprylyl alcohol, a fatty alcohol. It is an emollient and gives skin a velvet feel. The sources of Dicaprylyl Carbonate may be synthetic or from animals.
Caprylic/Capric Triglyceride is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.
Phenyl Trimethicone is a silicon-based polymer. It is derived from silica.
Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.
Bisabolol is pimarily used to add fragrance to a product. However, it is also famous for helping soothe skin.
Antioxidant 5 Benefits
Tetrahexyldecyl Ascorbate is a form of Vitamin C.
8 Benefits 3 Concerns
Retinol is a gold-standard ingredient for anti-aging. It is a form of Vitamin A and belongs to the class of retinoids that also includes tretinoin.
Antioxidant 4 Benefits May cause irritation
Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.
Lecithin is a term for a group of substances found in plants, animals, and humans. They are made up of mixture of fatty acids. These fatty acids usually are a mixture of phosphoric acid's choline ester connected to stearic, oleic, and palmitic acids. Most lecithins are created from plant ingredients scuh as sunflower.
Laminaria Ochroleuca Extract is a type of kelp. It helps sooth and hydrate the skin. By nourishing the skin's barrier, it may also help relieve irritation.
Antioxidant Helps hydrate Dry Skin
Avena Sativa Kernel Extract is is derived from colloidal oatmeal. Besides being a healthy breakfast, oats have many benefits in skincare too.
Not safe for Fungal Acne
Elaeis Guineensis Oil comes from the African Palm tree. This tree is native to Western and Southwestern Africa.
Hexylene Glycol is a surfactant. Glycols are a class of alcohols. Hexylene Glycol is a surfactant and emulsifier.
Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.
Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
Cyclopentasiloxane, Dimethiconol, Neopentyl Glycol Diheptanoate, Dicaprylyl Carbonate, Caprylic/Capric Triglyceride, Phenyl Trimethicone, Squalane, Bisabolol, Tetrahexyldecyl Ascorbate, Retinol, Tocotrienols, Tocopherol, Lecithin, Laminaria Ochroleuca Extract, Avena Sativa Kernel Extract, Elaeis Guineensis Oil, Stearyl Glycyrrhetinate, Hexylene Glycol, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Cyclopentasiloxane is a silicone used to improve texture and trap moisture. An easier name for this is D5.
D5 is considered lightweight and volatile. Volatile means it evaporates quickly after application. Once evaporated, D5 leaves a thin barrier that helps keep skin hydrated.
D5 is an emollient. Emollients help soften the skin and prevent water loss. Silicones create a silky texture in products. D5 helps other ingredients become more spreadable.
Studies show D5 is safe to use in skincare products. We recommend speaking with a skincare professional if you have concerns.
Learn more about CyclopentasiloxanePhenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.
It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.
Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.
This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.
Learn more about Caprylyl GlycolEthylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.
Hexylene Glycol is a surfactant. Glycols are a class of alcohols. Hexylene Glycol is a surfactant and emulsifier.
As a surfactant, Hexylene Glycol helps gather dirt and oil on your skin to be washed away.
As an emulsifier, Hexylene Glycol helps keep water and oil together. This prevents them from separating in a product. Hexylene Glycol also thins out the texture of a product by lessening viscosity.
Hexylene Glycol has a small molecular weight.
Learn more about Hexylene GlycolLecithin is a term for a group of substances found in plants, animals, and humans. They are made up of mixture of fatty acids. These fatty acids usually are a mixture of phosphoric acid's choline ester connected to stearic, oleic, and palmitic acids. Most lecithins are created from plant ingredients scuh as sunflower.
Lecithin is an emollient. Emollients help soften the skin and creates a barrier to keep moisture in.
As an emulsifier, it also helps prevent water and oil ingredients from separating. Lecithin can help ingredients be better absorbed by the skin. The phospholipids in Lecithin can produce liposomes. Liposomes help other ingredients get through the skin barrier.
Learn more about LecithinRetinol is a gold-standard ingredient for anti-aging. It is a form of Vitamin A and belongs to the class of retinoids that also includes tretinoin.
Why is retinol famous?
It has the most scientific studies backing up its skin benefits out of all the non-prescription ingredients.
Retinol is proven to:
This is why retinol is effective at removing wrinkles, fading dark spots, treating acne, and reducing the appearance of pores.
Studies show retinol is less effective when exposed to UV. Be sure to look for appropriate packaging to keep your retinol potent (similar to Vitamin C).
Using retinol or any retinoids will increase sun-sensitivity in the first few months. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.
We recommend speaking with a medical professional about using this ingredient during pregnancy.
Retinol may cause irritation in some people, so be sure to patch test. Experts recommend 'ramping up' retinol use: start using this ingredient once a week and work up to using it daily.
Read about Tretinoin
Learn more about RetinolTocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.
Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.
Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.
You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.
There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.
Learn more about TocopherolIngredient Ratings
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When to use
ZO Skin Health Daily Power Defense 51 ingredients
Paula's Choice Resist Intensive Wrinkle-Repair Retinol Serum 21 ingredients
