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Neutrogena Clear and Defend + Gel Moisturiser with Niacinamide and Panthenol Versus Clinique Dramatically Different Moisturizing Gel

General Moisturizer
General Moisturizer
American Brand United States
American Brand United States

Updated on December 18, 2023

Overview

What they are

These products are both reef safe general moisturizers. They have a total of 6 ingredients in common

Cool Features

They both contain exfoliants and Vitamin E

Suited For

They're both likely to be good for dry skin and brightening skin

Free From

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens or sulfates

What's Inside

They both contain silicones

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

At a glance

Click on any of the items below to learn more

Notable Ingredients

Benefits

Concerns

Notable Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Clear and Defend + Gel Moisturiser with Niacinamide and Panthenol
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Dimethicone Emollient, Skin Conditioning, Skin Protecting
1 / 0 Silicon Icon
SiliconSilicon Icon

Dimethicone is a silicone used for making products smooth and silky. It also has the added benefit of sealing in hydration. The amount of dimethicone found in beauty products is considered safe and non-comedogenic, meaning it won't clog pores.

1 Com. / 0 Irr.
Very Disliked Full details ->
Niacinamide Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconGood for Minimizing Pores IconGood for Dark Spots IconHelps fight Acne IconHelps brighten skin Icon
NiacinamideNiacinamide Icon 6 Benefits

Niacinamide has emerged as an all-star ingredient due to its many benefits.

Zea Mays Starch Abrasive, Absorbent, Skin Protecting
Exfoliant Icon
ExfoliantExfoliant Icon

Zea Mays Starch is starch made from corn. You might know this as cornstarch . It is used to thicken a product. It can replace talc as an absorbent.

Disliked Full details ->
Panthenol Skin Conditioning
0 / 0 Helps reduce irritation Icon
Helps reduce irritationHelps reduce irritation Icon

Panthenol is a common ingredient that helps hydrate and soothe the skin. It can be found naturally in our skin and hair.

0 Com. / 0 Irr.
Polyacrylamide

Polyacrylamide is a synthetic polymer. It is used to stabilize products and bind ingredients. When hydrated, Polyacrylamide forms a soft gel.

Disliked Full details ->
Phenoxyethanol Preservative
Preservative Icon
PreservativePreservative Icon

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

Very Disliked Full details ->
Cetearyl Olivate
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Cetearyl Olivate is an emulsifier and texture enhancer. It is derived from the fatty acids of olive oil and Cetearyl alcohol, and is biodegradable.

Disliked Full details ->
C13-14 Isoparaffin Emollient, Solvent
May worsen Oily Skin IconNot safe for Fungal Acne Icon
2 Concerns

C13-14 Isoparaffin is created from petroleum-based mineral oils. It is an emollient and helps thicken a product.

Very Disliked Full details ->
Sorbitan Olivate Emulsifying
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Sorbitan Olivate is created from the fatty acids in olive oil and sorbitol.

Very Disliked Full details ->
Caprylyl Glycol Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

Ethylhexylglycerin Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

Dimethicone Crosspolymer Emulsion Stabilising

Dimethicone Crosspolymer is a silicone created by modifying dimethicone with hydrocarbon side chains. Due to its large size, it does not penetrate skin. It is considered non-occlusive.

Very Disliked Full details ->
Carbomer Emulsion Stabilising, Gel Forming
1 / 0

Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.

1 Com. / 0 Irr.
Disliked Full details ->
Laureth-7 Emulsifying

Laureth-7 is created by the ethoxylation of lauryl alcohol using ethylene oxide. Lauryl alcohol is a fatty alcohol with hydrating properties.

Disliked Full details ->
Sodium Hydroxide Buffering

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

Tocopherol Antioxidant, Masking, Skin Conditioning
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin IconMay cause irritation Icon
Vitamin EVitamin E Icon AntioxidantAntioxidant Icon 4 Benefits May cause irritationMay cause irritation Icon

Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.

0-3 Com. / 0-3 Irr.
Dramatically Different Moisturizing Gel
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Dimethicone Emollient, Skin Conditioning, Skin Protecting
1 / 0 Silicon Icon
SiliconSilicon Icon

Dimethicone is a silicone used for making products smooth and silky. It also has the added benefit of sealing in hydration. The amount of dimethicone found in beauty products is considered safe and non-comedogenic, meaning it won't clog pores.

1 Com. / 0 Irr.
Very Disliked Full details ->
Isododecane Emollient, Solvent

Isododecane is a fragrance, emollient, and solvent.

Disliked Full details ->
Butylene Glycol Humectant, Masking, Skin Conditioning
1 / 0

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

1 Com. / 0 Irr.
Bis-Peg-18 Methyl Ether Dimethyl Silane Emollient, Humectant, Skin Conditioning

Bis-Peg-18 Methyl Ether Dimethyl Silane belongs to the siloxanes and silicones classes. It is synthetically created and has a waxy composition.

Disliked Full details ->
Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Laminaria Saccharina Extract Skin Protecting

We don't have a description for Laminaria Saccharina Extract.

Disliked Full details ->
Polygonum Cuspidatum Root Extract Antioxidant
Antioxidant Icon
AntioxidantAntioxidant Icon

Polygonum Cuspidatum Root Extract comes from the Japanese Knotweed plant native to Japan, Korea, and China.

Saccharomyces Lysate Extract Humectant, Skin Conditioning

Saccharomyces Lysate Extract is from the yeast Saccharomyces. This ingredient is created from the cell walls of Saccharomyces.

Cucumis Sativus Fruit Extract Emollient, Skin Conditioning

Cucumis Sativus Fruit Extract comes from the cucumber. Cucumis Sativus is native to South Asia and can now be found on every continent.

Hordeum Vulgare Extract Emollient, Skin Conditioning

We don't have a description for Hordeum Vulgare Extract.

Helianthus Annuus Seedcake Abrasive
Exfoliant IconNot safe for Fungal Acne Icon
ExfoliantExfoliant Icon Not safe for Fungal AcneNot safe for Fungal Acne Icon

Helianthus Annuus Seedcake is an exfoliant and isn't fungal acne safe.

Disliked Full details ->
Caffeine Skin Conditioning

Caffeine is most associated with coffee, tea, and cacao. In skincare, it helps with calming inflammation and anti-aging.

Trehalose Humectant, Moisturising

Trehalose is a disaccharide made of two glucose molecules (glucose is sugar!). Trehalose is used to help moisturize skin. It also has antioxidant properties.

Sodium Hyaluronate Humectant, Skin Conditioning
0 / 0 Hyaluronic Acid Icon
Hyaluronic AcidHyaluronic Acid Icon

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

0 Com. / 0 Irr.
Tocopheryl Acetate Antioxidant, Skin Conditioning
0 / 0 Vitamin E IconAntioxidant IconHelps brighten skin Icon
Vitamin EVitamin E Icon AntioxidantAntioxidant Icon Helps brighten skinHelps brighten skin Icon

Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.

0 Com. / 0 Irr.
Polysilicone-11

We don't have a description for Polysilicone-11.

Disliked Full details ->
Silica Abrasive, Absorbent
Exfoliant IconMay worsen Eczema IconMay worsen Rosacea Icon
ExfoliantExfoliant Icon 2 Concerns

Silica is a mineral naturally found in our skin. It helps to thicken and smooth the texture of a product. It also acts as an agent for other ingredients by increasing the absorption of other ingredients into the skin.

Disliked Full details ->
Propylene Glycol Dicaprate Emollient

Propylene Glycol Dicaprate is an emollient and emulsifier. It is created from a mixture of fatty acids.

Unknown Full details ->
Oleth-10 Emulsifying
2 / 1

Oleth-10 comes from oleyl alcohol. It is an emulsifier that helps reduce surface tension of dirt and pollutants to be washed away.

2 Com. / 1 Irr.
Very Disliked Full details ->
Lactobacillus Ferment Skin Conditioning

Lactobacillus Ferment is created by fermenting the Lactobacillus bacteria. It helps keep our skin's natural barrier and microbiome healthy.

Laureth-23 Cleansing, Emulsifying
3 / 0

Laureth-23 is created by reacting ethylene oxide with Lauryl Alcohol.

3 Com. / 0 Irr.
Very Disliked Full details ->
Laureth-4 Emulsifying, Masking
5 / 4 May worsen Oily Skin Icon
May worsen Oily SkinMay worsen Oily Skin Icon

Laureth-4 is created by reacting ethylene oxide with Lauryl Alcohol. It is a surfactant and emulsifier.

5 Com. / 4 Irr.
Unknown Full details ->
Ammonium Acryloyldimethyltaurate/Vp Copolymer

Ammonium Acryloyldimethyltaurate/Vp Copolymer (let's call it AAVC for short) is a synthetically created polymer. It's used as a film-forming agent and used to thicken the consistency of products.

Disliked Full details ->
Carbomer Emulsion Stabilising, Gel Forming
1 / 0

Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.

1 Com. / 0 Irr.
Disliked Full details ->
Caprylyl Glycol Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

Hexylene Glycol Emulsifying, Skin Conditioning, Solvent
0-2 / 0-1

Hexylene Glycol is a surfactant. Glycols are a class of alcohols. Hexylene Glycol is a surfactant and emulsifier.

0-2 Com. / 0-1 Irr.
Disliked Full details ->
Tromethamine Buffering, Masking

Tromethamine is an aliphatic compound. An aliphatic compound is an organic compound with open-chained carbon atoms. It is synthetically created. Tromethamine is used to balance pH and improve texture.

Disodium EDTA

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

Disliked Full details ->
Phenoxyethanol Preservative
Preservative Icon
PreservativePreservative Icon

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

Very Disliked Full details ->
CI 19140 Cosmetic Colorant

CI 19140 is also known as Tartrazine. Tartrazine is a synthetic dye used in cosmetics, foods, and medicine to add a yellow color.

Very Disliked Full details ->
CI 14700 Cosmetic Colorant
2 / 1

Ci 14700 is a synthetic red dye.

2 Com. / 1 Irr.
Unknown Full details ->
CI 15985 Cosmetic Colorant

Ci 15985 is a dye made from petroleum. It is synthetically created and approved by the FDA for use in foods and cosmetics.

Unknown Full details ->

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent
Loved

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Humectant, Skin Conditioning, Skin Protecting
Loved

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Emollient, Skin Conditioning, Skin Protecting
Very Disliked

Dimethicone is a silicone used for making products smooth and silky. It also has the added benefit of sealing in hydration. The amount of dimethicone found in beauty products is considered safe and non-comedogenic, meaning it won't clog pores.

Dimethicone has been found increase absorption in skin, boosting the benefits of other ingredients. While there is concern for the safety of dimethicone, the levels used in skincare are safe for use.

Preservative
Very Disliked

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

Emollient, Humectant, Skin Conditioning
Liked

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.

Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.

This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.

Learn more about Caprylyl Glycol
Emulsion Stabilising, Gel Forming
Disliked

Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.

Carbomer is commonly found in many types of cosmetics products. It is found to be safe in concentrations up to 15%. However, a high amount of carbomer can cause pilling or balling up of products. Most products contain 1% of less of carbomer.

Ingredient Ratings

Here's what our community thinks of the ingredients in these products.

Clear and Defend + Gel Moisturiser with Niacinamide and Panthenol
6
2
10
liked
mixed
disliked
not rated
Dramatically Different Moisturizing Gel
11
3
15
4
liked
mixed
disliked
not rated

When to use

5 Routines
40% use in am
60% use in pm
100% use every day
249 Routines
54% use in am
46% use in pm
97% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

Neutrogena Clear and Defend + Gel Moisturiser with Niacinamide and Panthenol 18 ingredients

3.0 /5
from 1 rating
Great Value (1) Hydrating (1) No Scent (1)
binxroth's avatar

cloud

9 days ago · Oily Skin
Review

I've had this for two weeks now and I can say It definitely keeps my skin hydrated but it does absolutely zero for oil production I swear it...

I've had this for two weeks now and I can say It definitely keeps my skin hydrated but it does absolutely zero for oil production I swear it probably makes me more oily. I end up having to powder my face with pressed powder to get the feeling of oiliness off my face.

I also use this at night time and when I wake up I can literally feel oil all over my face, especially my t-zone and forehead. I end up having to clip my hair back while I sleep because I thought it was my hair since it's thin, fine hair and gets oily quickly but it's just this moisturiser.

I've slept with different non-mattifying moisturisers during the night in the humid summer nights of 20+ degrees and woken up half as oily but I'm a greaseball when I wake up during the UK "summer" like cmon

Clinique Dramatically Different Moisturizing Gel 33 ingredients

4.8 /5
from 6 ratings
Hydrating (1) Light (1)
ErinLeighBee's avatar

ErinLeighBee

10 months ago · Combination Skin
Review

Perfect moisture level for daytime

Pitou's avatar

Pitou

3 years ago · Oily Skin
Review

Great for Oily skin!
I have oily skin and this moisturizer is my all time favourite amongst all other I have tried. It helps in maintaining my skin...

Great for Oily skin!
I have oily skin and this moisturizer is my all time favourite amongst all other I have tried. It helps in maintaining my skin protective barriers without clogging my pores or causing my skin to produce more oil.

It goes on the skin nice and absorb so well. In winter, I use one and a half pump and in summer I feel like a pump should be enough for the whole face. One bottle will last you around 3 months.

Great product!