Mizon Peptide 500 Versus Boots Peptide Serum
What's inside
What's inside
Key Ingredients
Benefits
Ingredients Side-by-side
Water
Skin ConditioningMethylpropanediol
SolventButylene Glycol
Humectant1,2-Hexanediol
Skin ConditioningPolyglyceryl-10 Oleate
Skin ConditioningEthylhexylglycerin
Skin ConditioningSodium Hyaluronate
HumectantCopper Tripeptide-1
Skin ConditioningAdenosine
Skin ConditioningDisodium EDTA
Biosaccharide Gum-1
HumectantBeta-Glucan
Skin ConditioningGlycine
BufferingTocopherol
AntioxidantSerine
MaskingGlutamic Acid
HumectantHouttuynia Cordata Extract
Skin ConditioningCentella Asiatica Extract
CleansingHydrolyzed Hyaluronic Acid
HumectantHydrolyzed Sodium Hyaluronate
Skin ConditioningHyaluronic Acid
HumectantHydroxypropyltrimonium Hyaluronate
Potassium Hyaluronate
Skin ConditioningAspartic Acid
MaskingLeucine
Skin ConditioningPentylene Glycol
Skin ConditioningAlanine
MaskingLysine
Skin ConditioningArginine
MaskingTyrosine
MaskingPhenylalanine
MaskingThreonine
Proline
Skin ConditioningValine
MaskingIsoleucine
Skin ConditioningSodium
Sodium Hyaluronate Crosspolymer
HumectantHistidine
HumectantMethionine
Skin ConditioningCysteine
AntioxidantSodium Acetylated Hyaluronate
HumectantPhosphatidylcholine
EmulsifyingAcetyl Hexapeptide-8
HumectantSh-Oligopeptide-1
Skin ConditioningOligopeptide-29
AntioxidantOligopeptide-32
AntiseborrhoeicPalmitoyl Pentapeptide-4
Skin ConditioningSh-Polypeptide-1
Skin ConditioningSh-Oligopeptide-2
Skin ConditioningSh-Polypeptide-22
Skin ConditioningPhenoxyethanol
PreservativeWater, Methylpropanediol, Butylene Glycol, 1,2-Hexanediol, Polyglyceryl-10 Oleate, Ethylhexylglycerin, Sodium Hyaluronate, Copper Tripeptide-1, Adenosine, Disodium EDTA, Biosaccharide Gum-1, Beta-Glucan, Glycine, Tocopherol, Serine, Glutamic Acid, Houttuynia Cordata Extract, Centella Asiatica Extract, Hydrolyzed Hyaluronic Acid, Hydrolyzed Sodium Hyaluronate, Hyaluronic Acid, Hydroxypropyltrimonium Hyaluronate, Potassium Hyaluronate, Aspartic Acid, Leucine, Pentylene Glycol, Alanine, Lysine, Arginine, Tyrosine, Phenylalanine, Threonine, Proline, Valine, Isoleucine, Sodium, Sodium Hyaluronate Crosspolymer, Histidine, Methionine, Cysteine, Sodium Acetylated Hyaluronate, Phosphatidylcholine, Acetyl Hexapeptide-8, Sh-Oligopeptide-1, Oligopeptide-29, Oligopeptide-32, Palmitoyl Pentapeptide-4, Sh-Polypeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-22, Phenoxyethanol
Water
Skin ConditioningGlycerin
HumectantButylene Glycol
HumectantNiacinamide
SmoothingPentylene Glycol
Skin Conditioning1,2-Hexanediol
Skin ConditioningBetaine
HumectantTrehalose
HumectantAmmonium Polyacryloyldimethyl Taurate
Emulsion StabilisingXanthan Gum
EmulsifyingSodium PCA
HumectantAllantoin
Skin ConditioningHydroxyacetophenone
AntioxidantCarnosine
Skin ConditioningSodium Lactate
BufferingPCA
HumectantPolyacrylate Crosspolymer-6
Emulsion StabilisingSodium Hyaluronate
HumectantDisodium EDTA
Serine
MaskingAlanine
MaskingGlycine
BufferingSodium Hyaluronate Crosspolymer
HumectantGlutamic Acid
HumectantLysine Hcl
Skin ConditioningCarbomer
Emulsion StabilisingThreonine
Arginine
MaskingPolysorbate 20
EmulsifyingProline
Skin ConditioningPalmitoyl Tripeptide-1
Skin ConditioningPalmitoyl Tetrapeptide-7
Skin ConditioningWater, Glycerin, Butylene Glycol, Niacinamide, Pentylene Glycol, 1,2-Hexanediol, Betaine, Trehalose, Ammonium Polyacryloyldimethyl Taurate, Xanthan Gum, Sodium PCA, Allantoin, Hydroxyacetophenone, Carnosine, Sodium Lactate, PCA, Polyacrylate Crosspolymer-6, Sodium Hyaluronate, Disodium EDTA, Serine, Alanine, Glycine, Sodium Hyaluronate Crosspolymer, Glutamic Acid, Lysine Hcl, Carbomer, Threonine, Arginine, Polysorbate 20, Proline, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.Â
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservativesÂ
Alanine is an amino acid and is already found in the human body. Our skin uses alanine to build collagen, elastin, and keratin.
Arginine is a semi-essential amino acid. This just means our bodies can product a bit on its own, but sometimes needs a little boost from food sources.
It is a part of your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
Here's an interesting thing about Arginine: your skin converts it into urea through the Krebs-Henseleit urea cycle. Urea is one of the most effective humectants your skin naturally produces.
A clinical study showed applying 2.5% arginine hydrochloride to atopic dermatitis skin showed significant urea levels in the stratum corneum and improved moisture in just four weeks.
Arginine is also a precursor to nitric oxide; nitric oxide improves microcirculation and supports wound healing and collagen synthesis.
One study found that an amino acid complex containing Arginine reduced skin irritation, improved hydration, and accelerated skin repair in clinical / in-vivo studies.
Arginine itself is an amino acid and not a fatty acid, oil, or ester. On its own, it's not a direct food source for Malassezia, or the yeast that causes fungal acne.
Learn more about ArginineButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolDisodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Learn more about Disodium EDTAGlutamic Acid is an amino acid that is found in all living organisms. Our bodies use this to help nerve cells in the brain communicate with other cells.
In cosmetics, glutamic acid is a famous humectant. It draws water from the air to your skin, keeping your skin hydrated (like hyaluronic acid).
An in-vitro study from 2024 found glutamic acid to play a role in inhibiting inflammation and thus a potential skin-soothing ingredient.
Other studies show it to be have potential wound healing, skin barrier repair, and hair growth properties.
Glutamic acid has poor solubility in water and other solvents.
Learn more about Glutamic AcidGlycine is the smallest amino acid and a key building block of collagen. It's part if your skin's Natural Moisturizing Factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
A study from 2022 found that an amino acid complex featuring taurine, arginine, and glycine significantly reduced skin irritation, improved redness, and accelerated the skin repair process.
Pentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.
The hydrophilic trait of Pentylene Glycol makes it a humectant. As a humectant, Pentylene Glycol helps draw moisture from the air to your skin. This can help keep your skin hydrated.
This property also makes Pentylene Glycol a great texture enhancer. It can also help thicken or stabilize a product.
Pentylene Glycol also acts as a mild preservative and helps to keep a product microbe-free.
Some people may experience mild eye and skin irritation from Pentylene Glycol. We always recommend speaking with a professional about using this ingredient in your routine.
Pentylene Glycol has a low molecular weight and is part of the 1,2-glycol family.
Learn more about Pentylene GlycolProline is a non-essential amino acid, meaning your body can make it on its own. In skincare, it is a skin conditioning ingredient that keeps skin soft and hydrated.
It makes up about 23% of the collagen molecule (collagen is the protein responsible for keeping your skin firm) and is involved in your skin's natural hyaluronic acid production. When applied topically, proline can penetrate the skin fairly well due to its small molecular size.
Reviews of this ingredient have found it to be neither a dermal irritant nor a sensitizer.
Fun fact: Proline can be found in protein-rich foods like meat, fish, eggs, and dairy.
Learn more about ProlineSerine is a non-essential amino acid (your body makes it on its own!). It is a major player in your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
Serine is one of your NMF's most abundant components that works as a skin-identical humectant. Its hydroxyl group grabs onto water molecules to boost hydration without any heaviness or occlusion.
Research on a hydrogel with serine confirmed this serine got delivered to your stratum corneum and demonstrated enhanced skin moisturization.
Interestingly serine also helps your skin produce filaggrin, a protein that keeps your skin barrier strong and used to create collagen.
Learn more about SerineSodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Learn more about Sodium HyaluronateSodium Hyaluronate Crosspolymer is a crosslinked version of sodium hyaluronate. This just means it's linked into a 3D mesh network that lets it be more stable and sit on skin as a cohesive, gel-like film rather than sinking into skin.
A 2016 human skin study found crosslinked HA increased epidermal water content by 7.6% over the control group and reduced transepidermal water loss by 27.8%.
A follow-up clinical trial found that a topical crosslinked HA serum applied after fillers, microneedling, or chemical peels was well-tolerated and enhanced skin quality at 14 / 28 days.
More recent research suggests that concentrations as low as 0.03% can act as a penetration enhancer for other skincare actives.
Learn more about Sodium Hyaluronate CrosspolymerThreonine is an amino-acid. It helps hydrate the skin and has antioxidant benefits.
Our skin uses threonine for creating collagen and elastin. Humans are not able to create threonine and must get it through eating foods such as fish, lentils, poultry, sesame seeds, and more.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water