This barrier-repair ampoule is formulated around Bifida Ferment Filtrate and Niacinamide to strengthen the skin barrier and refine the look of pores.
This barrier-repair ampoule is formulated around Bifida Ferment Lysate and Niacinamide to strengthen the skin barrier and soften the look of wrinkles.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningButylene Glycol
HumectantBifida Ferment Lysate
Skin ConditioningGlycerin
HumectantNiacinamide
Smoothing1,2-Hexanediol
Skin ConditioningPentylene Glycol
Skin ConditioningSqualane
EmollientPolyglyceryl-10 Laurate
Skin ConditioningBifida Ferment Filtrate
Skin ConditioningLactobacillus Ferment Lysate
Skin ConditioningLactococcus Ferment Lysate
Skin ConditioningSaccharomyces Ferment Filtrate
HumectantCarbomer
Emulsion StabilisingHydrogenated Lecithin
EmulsifyingTromethamine
BufferingXanthan Gum
EmulsifyingPropanediol
SolventEthylhexylglycerin
Skin ConditioningAdenosine
Skin ConditioningDextrin
AbsorbentTheobroma Cacao Seed Extract
AntioxidantSodium Hyaluronate
HumectantSodium Phytate
Lactobacillus/Pumpkin Fruit Ferment Filtrate
Skin ConditioningCutibacterium Granulosum Ferment Extract Filtrate
EmollientCaffeine
Skin ConditioningLeontopodium Alpinum Callus Culture Extract
AntioxidantPhysalis Alkekengi Calyx Extract
Skin ConditioningHydrolyzed Algin
Aureobasidium Pullulans Ferment
Skin ConditioningEpigallocatechin Gallate
AntioxidantBenzyl Glycol
SolventHydrolyzed Glycosaminoglycans
HumectantAsiatic Acid
Skin ConditioningAsiaticoside
AntioxidantMadecassic Acid
Skin ConditioningHydroxypropyltrimonium Hyaluronate
Sodium Hyaluronate Crosspolymer
HumectantHydrolyzed Hyaluronic Acid
HumectantSodium Acetylated Hyaluronate
HumectantHyaluronic Acid
HumectantCopper Tripeptide-1
Skin ConditioningHydrolyzed Sodium Hyaluronate
Skin ConditioningAcetyl Hexapeptide-8
HumectantPotassium Hyaluronate
Skin ConditioningWater, Butylene Glycol, Bifida Ferment Lysate, Glycerin, Niacinamide, 1,2-Hexanediol, Pentylene Glycol, Squalane, Polyglyceryl-10 Laurate, Bifida Ferment Filtrate, Lactobacillus Ferment Lysate, Lactococcus Ferment Lysate, Saccharomyces Ferment Filtrate, Carbomer, Hydrogenated Lecithin, Tromethamine, Xanthan Gum, Propanediol, Ethylhexylglycerin, Adenosine, Dextrin, Theobroma Cacao Seed Extract, Sodium Hyaluronate, Sodium Phytate, Lactobacillus/Pumpkin Fruit Ferment Filtrate, Cutibacterium Granulosum Ferment Extract Filtrate, Caffeine, Leontopodium Alpinum Callus Culture Extract, Physalis Alkekengi Calyx Extract, Hydrolyzed Algin, Aureobasidium Pullulans Ferment, Epigallocatechin Gallate, Benzyl Glycol, Hydrolyzed Glycosaminoglycans, Asiatic Acid, Asiaticoside, Madecassic Acid, Hydroxypropyltrimonium Hyaluronate, Sodium Hyaluronate Crosspolymer, Hydrolyzed Hyaluronic Acid, Sodium Acetylated Hyaluronate, Hyaluronic Acid, Copper Tripeptide-1, Hydrolyzed Sodium Hyaluronate, Acetyl Hexapeptide-8, Potassium Hyaluronate
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.
The way it works is fairly well mapped out:
Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.
The clinical backing is pretty solid too.
A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.
A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.
On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.
This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.
Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.
Learn more about AdenosineThis ingredient is a postbiotic made by fermenting Bifidobacterium (a probiotic bacteria) and then filtering out the liquid portion. It has skin conditioning properties.
Much of the evidence for this ingredient is borrowed from the lysate form of this ingredient, which has a much stronger research base.
This ingredient is generally considered fungal acne (Malassezia) safe; Bifidobacterium is a bacterium, not a yeast or fungus.
The fungal acne concern with fermented ingredients mainly applies to yeast-derived ferments like Saccharomyces and Galactomyces, because those are in the same kingdom as Malassezia and could theoretically contain residual compounds that feed it.
Bifida is a completely different organism, so on its own it doesn't provide a food source for the Malassezia yeast that causes fungal acne.
Learn more about Bifida Ferment FiltrateCarbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
Learn more about CarbomerNiacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Learn more about Niacinamide