cyrene Azelixir Azelaic Acid Chaga Mushroom Serum Versus Anua Azelaic Acid 15+ Intense Calming Serum
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningPropylene Glycol
Humectant
Azelaic Acid
Buffering
Sodium Hydroxide
Buffering1,2-Hexanediol
Skin Conditioning
Centella Asiatica Extract
Cleansing
Dipropylene Glycol
HumectantButylene Glycol
Humectant
Panthenol
Skin Conditioning
Hydroxyethylcellulose
Emulsion StabilisingGlycerin
Humectant
Ethylhexylglycerin
Skin ConditioningMelia Azadirachta Leaf Extract
Skin ConditioningSalicylic Acid
Masking
Biosaccharide Gum-1
Humectant
Allantoin
Skin Conditioning
Dipotassium Glycyrrhizate
Humectant
Melia Azadirachta Flower Extract
Skin ConditioningSodium Hyaluronate
Humectant
Melaleuca Alternifolia Leaf Oil
Antioxidant
Succinic Acid
BufferingTotarol
Antioxidant
Beta-Glucan
Skin Conditioning
Dextrin
AbsorbentTheobroma Cacao Extract
Skin ConditioningCentella Asiatica Leaf Extract
Skin Conditioning
Centella Asiatica Root Extract
Skin Conditioning
Madecassoside
Antioxidant
Asiaticoside
Antioxidant
Asiatic Acid
Skin Conditioning
Madecassic Acid
Skin Conditioning
Tocopherol
Antioxidant
Squalane
Emollient
Zinc PCA
Humectant
Chlorella Vulgaris Extract
Skin ConditioningCeramide NP
Skin Conditioning
Sodium Hyaluronate Dimethylsilanol
HumectantHydrolyzed Hyaluronic Acid
Humectant
Hydrolyzed Sodium Hyaluronate
Skin Conditioning
Hyaluronic Acid
Humectant
Potassium Hyaluronate
Skin ConditioningHydroxypropyltrimonium Hyaluronate
Sodium Hyaluronate Crosspolymer
Humectant
Sodium Acetylated Hyaluronate
Humectant
Water, Propylene Glycol, Azelaic Acid, Sodium Hydroxide, 1,2-Hexanediol, Centella Asiatica Extract, Dipropylene Glycol, Butylene Glycol, Panthenol, Hydroxyethylcellulose, Glycerin, Ethylhexylglycerin, Melia Azadirachta Leaf Extract, Salicylic Acid, Biosaccharide Gum-1, Allantoin, Dipotassium Glycyrrhizate, Melia Azadirachta Flower Extract, Sodium Hyaluronate, Melaleuca Alternifolia Leaf Oil, Succinic Acid, Totarol, Beta-Glucan, Dextrin, Theobroma Cacao Extract, Centella Asiatica Leaf Extract, Centella Asiatica Root Extract, Madecassoside, Asiaticoside, Asiatic Acid, Madecassic Acid, Tocopherol, Squalane, Zinc PCA, Chlorella Vulgaris Extract, Ceramide NP, Sodium Hyaluronate Dimethylsilanol, Hydrolyzed Hyaluronic Acid, Hydrolyzed Sodium Hyaluronate, Hyaluronic Acid, Potassium Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Sodium Hyaluronate Crosspolymer, Sodium Acetylated Hyaluronate
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Allantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.
Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.
Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.
It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.
Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.
This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.
Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.
Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.
Learn more about AllantoinAzelaic acid is a multitasker ingredient that helps treat acne, pigmentation, and irritation. It is a great option for sensitive skin.
What makes it special?
OTC Azelaic acid is usually available in concentrations from 10-15% and anything over requires a prescription.
Here's what each tier does best:
Unlike other acids, azelaic acid will not make your skin more photosensitive/sun sensitive.
Though this ingredient is naturally occurring in grains like wheat, rye, and barley, it is usually synthetically created for cosmetics to ensure stability and effectiveness.
Learn more about Azelaic AcidEthylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinPropylene Glycol is a synthetic, colorless, odorless liquid that has been a staple in cosmetics for decades. It is a skin conditioning agent, humectant, and solvent.
As a humectant, it draw water to the skin to reduce flaking and restore suppleness. It's also a solvent that helps dissolve other actives and keeps formulas stable across temperature changes.
The CIR Expert Panel has confirmed this ingredient to be nontoxic and clinical studies show no sensitization at cosmetic use concentrations.
True allergic reactions are quite rare: a 15-year retrospective study of 6,751 patients found only 0.31% had a positive reaction (and less than half were considered clinically relevant).
It seemed that when sensitization does occur, it's most commonly linked to topical medication (like corticosteroids) and not cosmetics. Allergic contact dermatitis also appears largely limited to individuals with underlying skin conditions.
Overall, propylene glycol is a well-studied ingredient that most people can tolerate without issue.
Learn more about Propylene GlycolSodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Learn more about Sodium HyaluronateWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water
