Sobel Skin RX Bio Hyaluronic Moisturizer Cream
A prescription with 35 ingredients, including hyaluronic acid, ceramides, and peptides.
Overview
What it is
Prescription with 35 ingredients that contains ceramides, hyaluronic acid and peptides
Cool Features
It is cruelty-free and reef safe
Suited For
It has ingredients that are good for anti aging, dry skin, sensitive skin and scar healing
Free From
It doesn't contain any harsh alcohols, common allergens, parabens, silicones or sulfates
Fun facts
Sobel Skin RX is from United States.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside
Ingredients List
Water
Skin ConditioningHelianthus Annuus Seed Oil
EmollientHydrogenated Phosphatidylcholine
EmulsifyingCaprylic/Capric Triglyceride
MaskingHydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingSodium Stearoyl Glutamate
CleansingSodium Hyaluronate
HumectantPentylene Glycol
Skin ConditioningButyrospermum Parkii Butter
Skin ConditioningPersea Gratissima Oil
Skin ConditioningMacadamia Ternifolia Seed Oil
EmollientRosa Moschata Seed Oil
EmollientRosmarinus Officinalis Leaf Extract
AntimicrobialCeramide NP
Skin ConditioningGlycerin
HumectantLeontopodium Alpinum Callus Culture Extract
AntioxidantChondrus Crispus Extract
Skin ConditioningXylitylglucoside
HumectantAnhydroxylitol
HumectantXylitol
HumectantDipeptide Diaminobutyroyl Benzylamide Diacetate
Skin ConditioningSorbitan Isostearate
EmulsifyingPhenoxyethanol
PreservativeEthylhexylglycerin
Skin ConditioningMelia Azadirachta Leaf Extract
Skin ConditioningMelia Azadirachta Flower Extract
Skin ConditioningAmino Esters-1
Skin ConditioningCoccinia Indica Fruit Extract
Skin ConditioningSolanum Melongena Fruit Extract
Skin ConditioningAloe Barbadensis Flower Extract
EmollientSimmondsia Chinensis Seed Oil
EmollientOcimum Sanctum Leaf Extract
Skin ConditioningOcimum Basilicum Flower/Leaf Extract
TonicCurcuma Longa Root Extract
MaskingCorallina Officinalis Extract
Skin ConditioningWater, Helianthus Annuus Seed Oil, Hydrogenated Phosphatidylcholine, Caprylic/Capric Triglyceride, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Sodium Stearoyl Glutamate, Sodium Hyaluronate, Pentylene Glycol, Butyrospermum Parkii Butter, Persea Gratissima Oil, Macadamia Ternifolia Seed Oil, Rosa Moschata Seed Oil, Rosmarinus Officinalis Leaf Extract, Ceramide NP, Glycerin, Leontopodium Alpinum Callus Culture Extract, Chondrus Crispus Extract, Xylitylglucoside, Anhydroxylitol, Xylitol, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Sorbitan Isostearate, Phenoxyethanol, Ethylhexylglycerin, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Amino Esters-1, Coccinia Indica Fruit Extract, Solanum Melongena Fruit Extract, Aloe Barbadensis Flower Extract, Simmondsia Chinensis Seed Oil, Ocimum Sanctum Leaf Extract, Ocimum Basilicum Flower/Leaf Extract, Curcuma Longa Root Extract, Corallina Officinalis Extract
Key Ingredients
Benefits
Concerns
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterHelianthus Annuus Seed Oil is a plant oil derived from the seeds of a sunflower.
It is rich in fatty acids, primarily linoleic acid and oleic acid. This gives it emollient and skin conditioning properties.
The reason this ingredient is so effective is because it forms a thin film on the skin that reduces transepidermal water loss (TEWL) while supplying linoleic acid to the stratum corneum to improve barrier strength.
The high linoleic acid content is particularly noteworthy for acne-prone skin.
Research suggests that acne-prone skin tends to be deficient in linoleic acid in sebum. Topical application may help replenish this to support a healthier follicular environment and less comedone-promoting sebum.
One randomized study found sunflower seed oil preserved skin barrier integrity in adult volunteers with and without atopic dermatitis (outperforming olive oil).
This ingredient is well-studied, gentle, and an effective emollient suitable for most skin types.
On fungal acne: This ingredient may not be Fungal acne (Malassezia folliculitis) safe. This is because it contains fatty acids with carbon chain lengths in the C11-C24 range.
Learn more about Helianthus Annuus Seed OilWe don't have a description for Hydrogenated Phosphatidylcholine yet.
This ingredient is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.
It helps thicken a product's formula and makes it easier to spread by dissolving clumping compounds.
Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid. Though it behaves like an oil, it is not technically one due to its chemical composition. It is very stable, resistant to oxidation, and unlikely to go rancid. In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Be sure to patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredientโs final chemical composition and not its marketing name or source.
Learn more about Caprylic/Capric TriglycerideThis is a synthetic polymer. It helps improve the texture of products by adding thickness and gel-like feel.
It is also an emulsifer, meaning it prevents ingredients such as oil and water from separating. It also helps evenly disperse other ingredients.
Sodium Stearoyl Glutamate is an amino-acid based emulsifier. It is made by combining stearic acid with L-glutamic acid and neutralizing it to a sodium salt.
As an emulsifier, it works mainly as an oil-in-water one and helps keep the oil and water in your formulas blended. It also contributes to a smooth, non-greasy skin feel.
This ingredient is biodegradable and commonly available in natural/COSMOS-certified grades.
Learn more about Sodium Stearoyl GlutamateSodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Learn more about Sodium HyaluronatePentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.
The hydrophilic trait of Pentylene Glycol makes it a humectant. As a humectant, Pentylene Glycol helps draw moisture from the air to your skin. This can help keep your skin hydrated.
This property also makes Pentylene Glycol a great texture enhancer. It can also help thicken or stabilize a product.
Pentylene Glycol also acts as a mild preservative and helps to keep a product microbe-free.
Some people may experience mild eye and skin irritation from Pentylene Glycol. We always recommend speaking with a professional about using this ingredient in your routine.
Pentylene Glycol has a low molecular weight and is part of the 1,2-glycol family.
Learn more about Pentylene GlycolThis ingredient is also known as shea butter. It is a plant-derived extract from the nuts of the Africa shea tree and one of the most well-studied emollients.
Because it has a high concentration of fatty acids (primarily oleic, stearic, and linoleic) it is able to form a protective barrier on the skin's surface. This helps seal in moisture and prevents transepidermal water loss (TEWL).
In vitro research found an increase in skin hydration by 58% and a decrease in TEWL by 37.8% after 24 hours of applying this ingredient (pretty impressive for a single ingredient!).
Besides hydration, shea butter also contains triterpenes that have anti-inflammatory potential. In particule, lupeol cinnamate has shown the highest anti-inflammatory activity in vivo.
Shea butter also contains vitamins A and E which may contribute to antioxidant activity.
While Shea Butter has an SPF rating of about 3-4, it is not a sunscreen replacement.
This ingredient may not be fungal acne safe because its fatty acids fall within the C11-C24 range that the Malassezia yeast can metabolize.
Learn more about Butyrospermum Parkii ButterThis ingredient is also known as Avocado oil. It's the cold-pressed oil from the flesh of the avocado fruit packed with fatty acids (mostly oleic acid).
The rich fatty acid profile allows it to function as a skin conditioning agent and emollient; it helps soften and smooth skin while reducing water loss.
Preclinical research has found that topical avocado oil increased collagen synthesis and reduced inflammation during wound healing, giving it some skin-repairing credibility.
The unsaponifiable fraction of the oil is also interesting: studies on avocado unsaponifiables showed that it helped skin produce more collagen and other structural compounds that support healing.
The CIR Expert Panel has found this ingredient to be non-irritating in formulations.
It's a great ingredient for dry or compromised skin. Just know it may not be fungal acne safe. This is because the oleic acid content falls within the range that Malassezia can use as a food source.
Learn more about Persea Gratissima OilMacadamia Ternifolia Seed Oil is the fixed oil obtained from Macadamia nut native to Australia. Due to its similarity with our skin's natural oils, macadamia oil absorbs easily without feeling greasy.
Macadamia seed oil is rich in fatty acids, including oleic acid (45-75%), palmitoleic acid (7-33%), and palmitic acid (6-12%). They also contain various B vitamins, iron, and magnesium.
Palmitoleic acid helps calm inflammation and supports wound healing while oleic acid helps hydrate the skin.
Due to the high amounts of palmitic and oleic acid, this ingredient may not be fungal acne safe. These are fatty acids that Malassezia yeast can feed on (C11-C24 chain length). If you're prone to fungal acne, this one's probably not for you.
You'll also see this ingredient listed as: Macadamia Integrifolia Seed Oil . This is the same ingredient; M. ternifolia is an older INCI naming convention for the edible macadamia nut, while M. integrifolia is the species actually cultivated for oil production. Both names refer to the same oil.
Learn more about Macadamia Ternifolia Seed OilRosa Moschata Seed Oil is an oil and isn't fungal acne safe.
Rosmarinus Officinalis Leaf Extract comes from rosemary. Rosemary is native to the Mediterranean.
While Rosmarinus Officinalis Leaf Oil can be volatile due to its fragrant properties, the fragrance components are usually removed in the leaf extract.
Rosemary Leaf Extract contains many antioxidants such as rosmarinic acid and caffeic acid. Rosemarinic acid, a compound found in rosemary leaf, has been found to help soothe skin conditions such as eczema and acne.
Learn more about Rosmarinus Officinalis Leaf ExtractCeramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.
Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.
This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.
A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.
Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.
Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.
Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.
Learn more about Ceramide NPGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinThis ingredient (LACCE) is a plant cell derived from the alpine plant, edelweiss. It is a humectant with antioxidant and skin protecting properties.
In-vitro and in-vivo research shows LACCE to exhibit strong antioxidant effects, including protecting skin against UVB induced stress. It also appears to support collagen production, improved skin elasticity, and wrinkle reduction.
Clinical application in humans shows topical use of LACCE can improve periorbital wrinkles (around the eyes), dermal density, and skin elasticity.
Cellular studies also suggest potential anti-inflammatory effects and upregulation of genes associated with barrier formation.
As with many plant extracts, a small number of people may experience sensitivity due to allergies.
Learn more about Leontopodium Alpinum Callus Culture ExtractChondrus Crispus Extract comes from a red algae native to the northern Atlantic coasts of Europe and North America. It helps hydrate the skin and is rich in antioxidants.
The antioxidants in chondrus crispus include lutein and zeaxanthin. Lutein has the ability to filter blue light from screens.
Other contents of chondrus crispus include polysaccharides, peptides, and amino acids. These help hydrate the skin.
What's the difference between algae and seaweed?
Algae is a broad term that includes seaweed. Not all algae is seaweed.
Xylitylglucoside is created from xylitol and glucose, two humectants.
Not surprisingly, this ingredient is also a humectant. It attracts and holds water in your skin, helping to maintain hydration.
This ingredient is most commonly found in a popular trio called Aquaxyl. Aquaxyl is made up of anhydroxylitol(24 - 34%), xylitylglucoside (35 - 50%), and xylitol (5 - 15%).
According to a manufacturer, Aquaxyl is known for a 3-D hydration concept and an anti-dehydration shield to reinforce the outer layer of skin.
Learn more about XylitylglucosideThis ingredient is created from dehydrating xylitol in acidic conditions. Xylitol is a famous sugar and humectant.
Much like its predecessor, anhydroxylitol is a humectant. Humectants attract and hold water to moisturize the skin.
This ingredient is most commonly found in a popular trio called Aquaxyl. Aquaxyl is made up of anhydroxylitol (24 - 34%), xylitylglucoside (35 - 50%), and xylitol (5 - 15%).
According to a manufacturer, Aquaxyl is known for a 3-D hydration concept and an anti-dehydration shield to reinforce the outer layer of skin.
This ingredient is often derived from plants such as wood and sugarcane.
Learn more about AnhydroxylitolXylitol is a humectant and prebiotic. It can help with dry skin.
In studies, xylitol has been shown to improve dry skin. It decreased transepidermal water loss, or when water passes through the skin and evaporates. Xylitol also showed to help improve the biomechanical properties of the skin barrier.
The prebiotic property of xylitol may also help reinforce our skin's natural microbiome. Having a healthy microbiome prevents infection by bad bacteria and helps with hydration.
As a humectant, Xylitol helps draw moisture from both the air and from deeper skin layers. This helps keep skin hydrated.
Xylitol is a sugar alcohol and commonly used as a sugar substitute. It is naturally occurring in plants such as strawberries and pumpkin.
Learn more about XylitolThis small molecule peptide has similar benefits to Argireline, the "botox" peptide.
According to the manufacturer, this peptide mimics snake venom to freeze muscles. This prevents muscle movement and contractions to prohibit the formation of fine lines and wrinkles.
While this seems promising, research is lacking in proving this ingredient to be as effective as botox.
Learn more about Dipeptide Diaminobutyroyl Benzylamide DiacetateSorbitan Isostearate is an emulsifer. It is created from isostearic acid and sorbitol.
As an emulsifier, it keeps the water and oil ingredients from separating. This keeps formulas stable and smooth.
In a 24 hour occlusive patch test on 56 subjects, 10% sorbitan isostearate was completely non-irritating. Most formulas use less than 10%.
Because it's a fatty acid ester, it may not be fungal acne safe since the Malassezia yeast can utilize it as a nutrient source.
Learn more about Sorbitan IsostearatePhenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinMelia Azadirachta Leaf Extract is extract from the neem plant.
The leaves of this tree contain flavonoids and polyphenols. These two compounds are antioxidants, anti-inflammatory, and antibacterial. Further research is needed as to their effects when applied on skin.
Melia Azadirachta Flower Extract is from the Neem tree. Neem trees originate from India.
Melia Azadirachta Flower Extract contains antioxidants. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells, such as pollution.
The flowers of this tree are lilac colored.
Learn more about Melia Azadirachta Flower ExtractWe don't have a description for Amino Esters-1 yet.
Coccinia Indica Fruit Extract is also known as Ivy Gourd Fruit Extract. It has skin conditioning properties.
The fruit is rich in flavonoids, phenolic acids, terpenoids, and sterols that show antioxidant and anti-inflammatory effect in vitro. This is because the fruit contains a thick mucilage that forms a protective and soothing layer on the skin's surface.
The extract itself has demonstrated antioxidant, soothing, and potential anti-allergy properties.
Most of this research is done in vitro and dedicated clinical studies on topical application are still limited.
Learn more about Coccinia Indica Fruit ExtractThis ingredient comes from eggplant (or aubergine). It has skin conditioning properties due to its abundance of antioxidants like Chlorogenic Acid, Caffeic Acid, and Nasunin.
Nasunin is the pigment concentrated in the purple peel and has demonstrated the abilityu to neutralize free radicals and bind excess iron in lab studies.
Lab studies have shown that eggplant extracts can lower oxidative stress and protect skin cell membranes from damage. A 2025 study found that specific compounds in eggplant (particularly a phenolamide called N-Trans-Feruloylputrescine) may support skin health by neutralizing 2-nonenal, a byproduct linked to aging skin.
Overall, this is a gentle, well-tolerated ingredient that adds a little extra antioxidant support to your routine.
Those with nighshade vegetable allergies (tomatoes, peppers, potatoes) should patch test as eggplant is part of the same family.
Learn more about Solanum Melongena Fruit ExtractAloe Barbadensis Flower Extract is an extract of the flowers of the aloe, Aloe barbadensis, Liliaceae
Aloe contains the antioxidants Vitamins A, C, and E.
It also contains sugars in the form of monosaccharides and polysaccharides, folic acid, choline, many common minerals such as calcium, 12 anthraquinones, fatty acids, amino acids, and Vitamin B12.
Aloe is known to be anti-inflammatory, moisturizing, antiseptic, healing, and protect against UV rays.
Learn more about Aloe Barbadensis Flower ExtractJojoba oil is one of the most well-studied plant-derived ingredients in cosmetics. It is an emollient with a special structure.
Because it is made up of 97-98% wax esters, it closely mirrors the linear monoesters found in human sebum. This makes it skin compatible, non-greasy, and lightweight.
Unlike other plant oils, jojoba wax doesn't easily penetrate skin. It mostly works in the uppermost layers as an emollient. This just means it forms a light barrier on the skin to help retain moisture.
Formulations with jojoba esters up to 90% reduced transepidermal water loss (TEWL) and increased barrier recovery by 81% (outperforming bisabolol at 47%).
Besides barrier support, the science also suggests jojoba to have anti-inflammatory effects and potential applications for skin infections, aging, and wound healing.
Fun fact: Indigenous cultures have used jojoba as a moisturizer and to help treat burns for centuries.
Due to its fatty acid content, Jojoba oil may not be fungal acne safe.
Learn more about Simmondsia Chinensis Seed OilOcimum Sanctum Leaf Extract comes from the Holy Basil plant. Holy Basil is native to India.
Holy Basil is rich in antioxidants due to its high romarinic acid, ferulic acid, and rutin content. This gives it skin brightening and soothing properties.
While Holy Basil has many claims to help fight acne, more research is needed.
One thing to note is the presence of tannins; tannins are naturally found in nature. However, this compound may be skin-sensitizing.
Learn more about Ocimum Sanctum Leaf ExtractWe don't have a description for Ocimum Basilicum Flower/Leaf Extract yet.
Curcuma Longa Root Extract is from the spice, turmeric. Besides being a healthy and delicious spice, turmeric also has plenty of skincare benefits. It has anti-inflammatory, antioxidant, and anti-microbial properties.
Turmeric contains curcumin, an antioxidant. Antioxidants help neutralize unstable free-radical molecules. Free-radical molecules may damage your skin's cells and DNA. Curcumin may help with anti-aging.
Curcumin also has anti-inflammatory properties and can help soothe skin and reduce irritation. On top of that, curcumin has been shown to help prevent hyperpigmentation from sun damage.
The anti-microbial property of turmeric can make it effective in treating acne. This property has also been shown to help regulate the production of sebum.
Learn more about Curcuma Longa Root ExtractCorallina Officinalis Extract is from the red seaweed, Corallina Officinalis. This seaweed is found all over the world but is most common in the rocky shores of Great Britain and Ireland.
Corallina Officinalis Extract contains antioxidant and emollient properties.
Extracted polysaccharides, galactose and xylose, in red algae showed antioxidant activity. Antioxidants help with anti-aging by neutralizing free-radical molecules. Free-radical molecules may damage your skin cells and DNA. Galactose is also a PHA.
Corallina Officinalis is structurally similar to coral due to its high calcium content.
Learn more about Corallina Officinalis ExtractReviews
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Sobel Skin RX is a American brand
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The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about usยท Published March 15, 2023