Sisley Paris Hydra-Global Serum Anti-Aging Hydration Booster Versus Lancôme Advanced Génifique Yeux Light-Pearl Eye & Lash Enhancing Concentrate
This hydrating serum is formulated around Saccharide Isomerate and Panthenol to hydrate skin and soften the look of wrinkles.
This anti-aging eye moisturizer is formulated around Bifida Ferment Lysate and Adenosine to soften the look of wrinkles and strengthen the skin barrier.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningGlycerin
HumectantButylene Glycol
HumectantDimethicone
EmollientIsodecyl Neopentanoate
EmollientAlcohol Denat.
AntimicrobialPolyacrylate Crosspolymer-6
Emulsion StabilisingSaccharide Isomerate
HumectantPanthenol
Skin ConditioningTocopheryl Acetate
AntioxidantLeontopodium Alpinum Flower/Leaf Extract
Skin ConditioningMentha Aquatica Leaf Extract
Skin ConditioningIris Florentina Root Extract
MaskingYeast Extract
Skin ConditioningMalachite Extract
AntioxidantAdenosine
Skin ConditioningViola Tricolor Extract
EmollientCryptomeria Japonica Bud Extract
Skin ConditioningCeratonia Siliqua Seed Extract
Skin ConditioningLavandula Angustifolia Oil
MaskingThymus Mastichina Flower Oil
Skin ConditioningSalvia Officinalis Oil
MaskingHydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingXanthan Gum
EmulsifyingDisodium EDTA
Citric Acid
BufferingPolysorbate 60
EmulsifyingSorbitan Isostearate
EmulsifyingEthylhexylglycerin
Skin ConditioningSodium Citrate
BufferingSodium Hydroxide
BufferingPhenoxyethanol
PreservativeSodium Benzoate
MaskingLinalool
PerfumingLimonene
PerfumingGeraniol
PerfumingWater, Glycerin, Butylene Glycol, Dimethicone, Isodecyl Neopentanoate, Alcohol Denat., Polyacrylate Crosspolymer-6, Saccharide Isomerate, Panthenol, Tocopheryl Acetate, Leontopodium Alpinum Flower/Leaf Extract, Mentha Aquatica Leaf Extract, Iris Florentina Root Extract, Yeast Extract, Malachite Extract, Adenosine, Viola Tricolor Extract, Cryptomeria Japonica Bud Extract, Ceratonia Siliqua Seed Extract, Lavandula Angustifolia Oil, Thymus Mastichina Flower Oil, Salvia Officinalis Oil, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Xanthan Gum, Disodium EDTA, Citric Acid, Polysorbate 60, Sorbitan Isostearate, Ethylhexylglycerin, Sodium Citrate, Sodium Hydroxide, Phenoxyethanol, Sodium Benzoate, Linalool, Limonene, Geraniol
Water
Skin ConditioningBifida Ferment Lysate
Skin ConditioningPropanediol
SolventGlycerin
HumectantAlcohol Denat.
AntimicrobialDimethicone
EmollientC13-14 Isoparaffin
EmollientEscin
TonicTocopheryl Acetate
AntioxidantSodium Benzoate
MaskingPhenoxyethanol
PreservativeAdenosine
Skin ConditioningCaffeine
Skin ConditioningPolyacrylamide
Chlorphenesin
AntimicrobialPolymethylsilsesquioxane
Chlorella Vulgaris Extract
Skin ConditioningSalicyloyl Phytosphingosine
Skin ConditioningDimethicone/Vinyl Dimethicone Crosspolymer
Skin ConditioningAmmonium Polyacryloyldimethyl Taurate
Emulsion StabilisingDimethiconol
EmollientPentaerythrityl Tetraethylhexanoate
EmollientXanthan Gum
EmulsifyingCaprylic/Capric Triglyceride
MaskingBis-PEG/PPG-16/16 PEG/PPG-16/16 Dimethicone
EmollientBHT
AntioxidantLaureth-7
EmulsifyingWater, Bifida Ferment Lysate, Propanediol, Glycerin, Alcohol Denat., Dimethicone, C13-14 Isoparaffin, Escin, Tocopheryl Acetate, Sodium Benzoate, Phenoxyethanol, Adenosine, Caffeine, Polyacrylamide, Chlorphenesin, Polymethylsilsesquioxane, Chlorella Vulgaris Extract, Salicyloyl Phytosphingosine, Dimethicone/Vinyl Dimethicone Crosspolymer, Ammonium Polyacryloyldimethyl Taurate, Dimethiconol, Pentaerythrityl Tetraethylhexanoate, Xanthan Gum, Caprylic/Capric Triglyceride, Bis-PEG/PPG-16/16 PEG/PPG-16/16 Dimethicone, BHT, Laureth-7
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.
The way it works is fairly well mapped out:
Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.
The clinical backing is pretty solid too.
A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.
A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.
On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.
This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.
Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.
Learn more about AdenosineAlcohol Denat. is an alcohol with a denaturant property. It is created by mixing ethanol with other additives.
The "denat" part just means "denatured"; common denaturants include Denatonium Benzoate, t-butyl alcohol, and Diethyl Phthalate. This step makes the alcohol undrinkable (and lets brand skip taxes related to beverage alcohol).
This ingredient gets a bad rep because it is irritating and drying due to its astringent property. Astringents draw out natural oils in tissue to constrict pores and dry out your skin.
However, alcohol denat. is not all that bad.
Due to its low molecular weight, alcohol denat. tends to evaporate quickly. One study on pig skin found half of applied alcohol evaporated in 10 seconds and less than 3% stayed on skin.
This also helps other ingredients become better absorbed upon application.
Studies are conflicted about whether this ingredient causes skin dehydration. One study from 2005 found adding emollients to propanol-based sanitizer decreased skin dryness and irritation. Another study found irritation only occurs if your skin is already damaged.
Small amounts of alcohol are generally tolerated by oily skin or people who live in humid environments.
The rule of thumb is this ingredient will probably not affect your skin much if it is near the end of an ingredients list.
One thing to note:
People with ALDH2 (aldehyde dehydrogenase 2) deficiency may experience skin irritation from continued alcohol use. About 8% of the world's population have this deficiency.
The Cosmetic Ingredient Review Expert Panel has determined denatured alcohols to be safe for use in concentrations between 0.05% and 12% (depending on which denaturant is used).
Also...
This ingredient has antimicrobial and solvent properties.
The antimicrobial property helps preserve products and increase their shelf life. As a solvent, it helps dissolve other ingredients.
Look for formulas that contain glycerin, hyaluronic acid, or panthenol if you want to offset any drying effect.
This ingredient will trip away your skin's natural oils/lipids that help it lock in moisture. This can worsen dryness, trigger eczema flare-ups, and aggravate rosacea.
Be sure to patch test any product with this ingredient if you have dry or sensitive skin, eczema, or rosacea.
Learn more about Alcohol Denat.Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Learn more about DimethiconeGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinPhenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Learn more about PhenoxyethanolSodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.
Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.
Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.
It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.
Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.
We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.
Learn more about Sodium BenzoateTocopheryl Acetate is a stable, shelf-friendly form of vitamin E.
Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.
It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.
One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.
Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.
Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.
The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.
Most leave-on skincare keeps it at the lower end, often between 0.5-1%.
Learn more about Tocopheryl AcetateWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan Gum