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Updated on October 29, 2023

Overview

What they are

These products are both reef safe general moisturizers. They have a total of 4 ingredients in common

Cool Features

They both contain hyaluronic acid

Suited For

They're both likely to be good for dry skin, brightening skin, sensitive skin, scar healing and better texture

Free From

They both do not contain any harsh alcohols, common allergens, oils, parabens or sulfates

What's Inside

They both contain silicones

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Neutrogena Hydro Boost Water Gel US
Neutrogena Hydro Boost Water Gel
General Moisturizer
American Brand United States
Dot & Key Skincare 72 HR Hydrating Gel Moisturizer + Probiotics

Ingredient Info

Click any item below to learn more and see relevant ingredients

At a glance

Click on any of the items below to learn more

Benefits

Concerns

Benefits

Concerns

Ingredients Side-by-side

found in both products
Hydro Boost Water Gel
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Dimethicone Emollient, Skin Conditioning, Skin Protecting
1 / 0 Silicon Icon
SiliconSilicon Icon

Dimethicone is a silicone used for making products smooth and silky. It also has the added benefit of sealing in hydration. The amount of dimethicone found in beauty products is considered safe and non-comedogenic, meaning it won't clog pores.

1 Com. / 0 Irr.
Very Disliked Full details ->
Cetearyl Olivate
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Cetearyl Olivate is an emulsifier and texture enhancer. It is derived from the fatty acids of olive oil and Cetearyl alcohol, and is biodegradable.

Disliked Full details ->
Sorbitan Olivate Emulsifying
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Sorbitan Olivate is created from the fatty acids in olive oil and sorbitol.

Very Disliked Full details ->
Sodium Hyaluronate Humectant, Skin Conditioning
0 / 0 Hyaluronic Acid Icon
Hyaluronic AcidHyaluronic Acid Icon

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

0 Com. / 0 Irr.
Serine Masking, Skin Conditioning

Serine is an amino acid naturally found in our body. Our bodies use amino acids to create protein.

Glycine Buffering, Skin Conditioning

Glycine is an amino acid that helps build proteins. It is already present in our skin as our bodies produce them naturally.

Alanine Masking, Skin Conditioning

Alanine is an amino acid and is already found in the human body.

Threonine

Threonine is an amino-acid. It helps hydrate the skin and has antioxidant benefits.

Arginine Masking, Skin Conditioning
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Arginine is an amino acid that is important for human development. Your body uses is it to produce hair keratin and skin collagen.

Proline Skin Conditioning

Proline is an amino-acid. It helps moisturize the skin and plays an important role in creating proteins.

Lysine Hcl Skin Conditioning
Helps hydrate Dry Skin Icon
Helps hydrate Dry SkinHelps hydrate Dry Skin Icon

Lysine HCl is an alpha amino acid salt.

Glutamic Acid Humectant

Glutamic Acid is an amino acid that is found in all living organisms. Our bodies use this to help nerve cells in the brain communicate with other cells.

Sodium PCA Humectant, Skin Conditioning
0 / 0

Sodium PCA is the sodium salt of pyroglutamic acid and is naturally occurring on human skin.

0 Com. / 0 Irr.
PCA Humectant, Moisturising

PCA is derived from amino acids and is naturally found in our skin's barrier.

Sodium Lactate Buffering, Humectant

Sodium Lactate is the sodium salt of lactic acid, an AHA. It is a humectant and used to adjust the pH of a product.

Urea Buffering, Humectant, Skin Conditioning
Helps hydrate Dry Skin IconGood for Skin Texture IconMay worsen Eczema IconMay worsen Rosacea Icon
2 Benefits 2 Concerns

Urea is also called carbamide and is the diamide of carbonic acid. In cosmetics, urea is used to hydrate the skin. It also provides exfoliation in higher concentrations.

Sodium Chloride Masking
Can worsen Dry Skin IconBad for Acne Prone Skin IconMay worsen Rosacea Icon
3 Concerns

Chances are, you eat sodium chloride every day. Sodium Chloride is also known as table salt.

Very Disliked Full details ->
Citric Acid Buffering, Masking
AHA IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconHelps brighten skin IconMay cause irritation IconMay worsen Rosacea Icon
AHAAHA Icon 4 Benefits 2 Concerns

Citric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).

Disliked Full details ->
Betaine Humectant, Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon
3 Benefits

Betaine is a common humectant (a substance that promotes retention of moisture). It's known to be gentle on the skin and can help balance hydration.

Allantoin Skin Conditioning, Skin Protecting, Soothing
0 / 0 Helps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon
3 Benefits

Allantoin plays a role in soothing and moisturizing the skin. Because of this, it is often added to products with strong active ingredients.

0 Com. / 0 Irr.
Fructose Humectant

Fructose is fruit/plant sugar. It can be found in apples, figs, and honey.

Maltose Masking, Moisturising, Skin Conditioning

We don't have a description for Maltose.

Unknown Full details ->
Trehalose Humectant, Moisturising

Trehalose is a disaccharide made of two glucose molecules (glucose is sugar!). Trehalose is used to help moisturize skin. It also has antioxidant properties.

Glucose Humectant

Glucose is a simple sugar and is the most important source of energy in all organisms.

Pentylene Glycol Skin Conditioning, Solvent

Pentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.

Synthetic Beeswax Emulsion Stabilising
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Synthetic beeswax is created to be identical in structure to beeswax. It possesses the same occlusive and emulsion properties.

Very Disliked Full details ->
Polyacrylate Crosspolymer-6 Emulsion Stabilising

Polyacrylate Crosspolymer-6 is a texture enhancer and pH adjuster.

Disliked Full details ->
Dimethicone Crosspolymer Emulsion Stabilising

Dimethicone Crosspolymer is a silicone created by modifying dimethicone with hydrocarbon side chains. Due to its large size, it does not penetrate skin. It is considered non-occlusive.

Very Disliked Full details ->
Dimethiconol Emollient, Moisturising

Dimethiconol is a silicone that resembles the popular dimethicone. Like other silicones, it is an emollient. Emollients create a thin film on skin to prevent moisture from escaping.

Disliked Full details ->
Ethylhexylglycerin Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

Caprylyl Glycol Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

Sodium Hydroxide Buffering

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

72 HR Hydrating Gel Moisturizer + Probiotics
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Cyclopentasiloxane Emollient, Skin Conditioning, Solvent
Silicon Icon
SiliconSilicon Icon

Cyclopentasiloxane is a silicone used to improve texture and trap moisture. An easier name for this is D5.

Disliked Full details ->
Dimethicone Crosspolymer Emulsion Stabilising

Dimethicone Crosspolymer is a silicone created by modifying dimethicone with hydrocarbon side chains. Due to its large size, it does not penetrate skin. It is considered non-occlusive.

Very Disliked Full details ->
Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Polyacrylamide

Polyacrylamide is a synthetic polymer. It is used to stabilize products and bind ingredients. When hydrated, Polyacrylamide forms a soft gel.

Disliked Full details ->
C13-14 Isoparaffin Emollient, Solvent
May worsen Oily Skin IconNot safe for Fungal Acne Icon
2 Concerns

C13-14 Isoparaffin is created from petroleum-based mineral oils. It is an emollient and helps thicken a product.

Very Disliked Full details ->
Laureth-7 Emulsifying

Laureth-7 is created by the ethoxylation of lauryl alcohol using ethylene oxide. Lauryl alcohol is a fatty alcohol with hydrating properties.

Disliked Full details ->
Silanetriol

We don't have a description for Silanetriol.

Unknown Full details ->
Hyaluronic Acid Humectant, Moisturising, Skin Conditioning
Hyaluronic Acid IconGood for Skin Texture IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin IconMay cause irritation Icon
Hyaluronic AcidHyaluronic Acid Icon 4 Benefits May cause irritationMay cause irritation Icon

Hyaluronic acid is naturally found in healthy skin. It is a humectant, meaning it draws moisture to your skin.

Divinyldimethicone/Dimethicone Copolymer

We don't have a description for Divinyldimethicone/Dimethicone Copolymer.

Unknown Full details ->
C12-13 Pareth-23 Cleansing, Emulsifying

We don't have a description for C12-13 Pareth-23.

Unknown Full details ->
C12-13 Pareth-3 Emulsifying

We don't have a description for C12-13 Pareth-3.

Unknown Full details ->
Dimethylsilanol Hyaluronate Humectant, Moisturising, Skin Conditioning

We don't have a description for Dimethylsilanol Hyaluronate.

Saccharide Isomerate Humectant

Saccharide Isomerate comes from sugars found in corn. It is a skin hydrator.

Oryza Sativa Bran Water Masking, Perfuming
Fragrance Icon
FragranceFragrance Icon

Oryza Sativa Bran Water comes from the outer layer of a rice kernel. It is a byproduct of milling rice, or the operation to produce a whole grain rice product.

Saccharomyces/Xylinum/Black Tea Ferment Skin Conditioning
Helps reduce irritation Icon
Helps reduce irritationHelps reduce irritation Icon

Saccharomyces/Xylinum/Black Tea Ferment can be good for be good for sensitive skin.

Avena Sativa Meal Extract Soothing

We don't have a description for Avena Sativa Meal Extract.

Pyrus Malus Fruit Extract Skin Conditioning

Pyrus Malus Fruit Extract is extract from Apples. Apples are rich in Vitamin C, sugars, and antioxidants.

Lactobacillus Skin Conditioning

Lactobacillus is a type of bacteria. It makes up most of the food fermenting lactic acid bacteria. It is used to create wine, yogurt, cheese, sauerkraut, pickles, beer, cider, kimchi, cocoa, kefir.

Maltodextrin Absorbent, Emulsion Stabilising, Skin Conditioning

Maltodextrin is a polysaccharide. It is derived from starch such as rice, corn, wheat, or potato starch.

Sodium Hydroxide Buffering

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

Methylsilanol Mannuronate Skin Conditioning

We don't have a description for Methylsilanol Mannuronate.

Unknown Full details ->
Phenoxyethanol Preservative
Preservative Icon
PreservativePreservative Icon

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

Very Disliked Full details ->
Methylisothiazolinone Preservative
Preservative IconMay cause irritation IconMay worsen Eczema Icon
PreservativePreservative Icon 2 Concerns

MI is a preservative and known skin irritant. In the past, MI was used for its ability to prevent bacteria, yeast, and fungi growth in low doses.

Very Disliked Full details ->
Acrylates/C10-30 Alkyl Acrylate Crosspolymer Emulsion Stabilising

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken and improve the texture of products.

Disliked Full details ->
Disodium EDTA

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

Disliked Full details ->
CI 42090 Cosmetic Colorant

Ci 42090 is a synthetic dye created from petroleum. It is used to give a bright blue color to cosmetics, medicine, and food.

Unknown Full details ->

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent
Loved

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Humectant, Skin Conditioning, Skin Protecting
Loved

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Emulsion Stabilising
Very Disliked

Dimethicone Crosspolymer is a silicone created by modifying dimethicone with hydrocarbon side chains. Due to its large size, it does not penetrate skin. It is considered non-occlusive.

Dimethicone Crosspolymer is used to stabilize and thicken products. It also helps give products a silky feel.

Buffering
Mixed

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.

Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.

"Alkaline" refers to a high pH level. A low pH level would be considered acidic.

Learn more about Sodium Hydroxide

Ingredient Ratings

Here's what our community thinks of the ingredients in these two products.

Hydro Boost Water Gel
20
4
9
1
liked
mixed
disliked
not rated
72 HR Hydrating Gel Moisturizer + Probiotics
10
2
9
6
liked
mixed
disliked
not rated

When to use

1,580 Routines
54% use in am
46% use in pm
98% use every day
When to use See routines that use it ->
4 Routines
75% use in am
25% use in pm
100% use every day

Reviews

Here's what our community thinks

Neutrogena Hydro Boost Water Gel 34 ingredients

3.2 /5
from 18 ratings
Light (3) Absorbs Well (3) Hydrating (2)
BaiFengxi's avatar

BaiFengxi

1 month ago · Combination Skin
Review

I got this because it was one of the products I used two years ago that moisturized my skin without making me oily. However, they came out with a...

I got this because it was one of the products I used two years ago that moisturized my skin without making me oily. However, they came out with a new formula earlier this year. I decided to try it anyways and right off the bat I could tell it was different. The old formula was unscented. I'm sensitive to scents, and the new one smells like strong herbal shampoo. I put it on and it stung a little. I don't have a damaged barrier and none of the new products I've tried have burned at all. This one stung a little. So I ended up just washing it all off. I did not like this product. Just note the dates on the other reviews. If they are earlier than January 2024, be aware that Neutrogena discontinued that formula and the came out with the new one, which is what I talked about in this review.

jeanpaul2301's avatar

jeanpaul2301

3 years ago · Combination Skin
Review

Great mosturizer!
Tried this out of curiosity with my mom, both of us were pleased with our results. She has normal to dry skin and I have combo...

Great mosturizer!
Tried this out of curiosity with my mom, both of us were pleased with our results. She has normal to dry skin and I have combo skin with fungal acne. She uses this everyday as soon as she gets out of the shower; without it her skin would feel dry as a desert. In my case, I put this on after using the Cetaphil daily facial cleanser. I know this product isn't fungal acne safe but I have combo skin, so I put it on the areas of my face that instead of having fungal acne, are kind of dry (mostly my cheeks, nose and neck). This moisturizer makes my skin feel refreshed, hydrated and healthy. It definitely has fragrance, but It's nice and light. I won't give it 5 stars just because it isn't fungal acne safe:)

Dot & Key Skincare 72 HR Hydrating Gel Moisturizer + Probiotics 27 ingredients

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