Eucerin Complete Hydration Lotion SPF 50 Face & Body Versus Cetaphil Dermacontrol Oil Absorbing Moisturizer SPF 30 - Sensitive & Oily Skin

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

You'll often see it paired with other UV filters to boost overall SPF because octisalate is a fairly week filter on its own.

The reason you'll see it so often is because it can help solubilize and stabilize the trickier filters like oxybenzone and avobenzone.

Unlike these filters, octisalate has pretty good photostability and doesn't create skin-damaging free radicals when exposed to sunlight.

The fatty-alcohol part of the molecule also gives it a light, emollient feel so it doubles as a nice texture enhancer.

Usage levels vary around the world:

Safety-wise, this ingredient has a pretty reassuring track record. The EU's Scientific Committee on Consumer Products (SCCP) found very low skin penetration in human skin tests and negative results for irritation, phototoxicity, and photoallergy.

The real-world allergy risk is pretty low too; a 2012 European study of 1,031 people recorded only 2 reactions to it (a rate of 0.19%).

You might have seen scary headlines about sunscreen getting into your blood.

In 2019, the FDA found that several chemical filters can absorb through the skin and show up in the bloodstream at small but measurable levels.

Here's the important part: these tiny levels are just a cutoff the FDA uses to decide which ingredients need more testing and doesn't mean anything harmful was found.

The researchers were clear that the results are no reason to stop wearing sunscreen.

Your skin makes its own natural anti-inflammatory hormone called cortisol and it also has an enzyme that switches cortisol off. Glycyrrhetinic Acid slows down that enzyme so your skin's natural calming power sticks around a little longer.

The research is pretty encouraging, especially for calming redness:

This is a good ingredient to look out for if your skin gets red, itchy, or irritated easily. It's also nice for anyone recovering from a harsh treatment or whose skin barrier is feeling a bit stressed.

It's typically found up to 2% because a little goes a long way.

Safety experts at the Cosmetic Ingredient Review found it safe as used in cosmetics. Even at 6%, three times the typical amount, it didn't cause irritation or allergic reactions in clinical testing.

Allergies to it are very rare with only a handful of reported cases over the years. But as with any new product, it's a good idea to patch test if you have reactive skin.

Fun fact: Glycyrrhetinic Acid is also used as a flavoring agent. Its sweet licorice roots mean it's sometimes used to help mask bitter tastes in medicine.