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Updated on June 28, 2024

Overview

What they are

These products are both cruelty-free and reef safe . They have a total of 6 ingredients in common

Cool Features

They both contain niacinamide

Suited For

They're both likely to be good for fighting acne, dry skin, brightening skin, sensitive skin, oily skin, reducing pores and dark spots

Free From

They both do not contain any common allergens, fragrances, oils, parabens or sulfates

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Aestura A-Cica 365 Blemish Calming Serum
Isntree Onion Newpair B5 Ampoule

Ingredient Info

Click any item below to learn more and see relevant ingredients

At a glance

Click on any of the items below to learn more

Notable Ingredients

Benefits

Concerns

Notable Ingredients

Benefits

Ingredients Side-by-side

found in both products
A-Cica 365 Blemish Calming Serum
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Butylene Glycol Humectant, Masking, Skin Conditioning
1 / 0

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

1 Com. / 0 Irr.
Dipropylene Glycol Masking, Solvent

Dipropylene Glycol is a synthetically created stabilizer and solvent. It is a part of the glycol class in the alcohol family.

Disliked Full details ->
Betaine Humectant, Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon
3 Benefits

Betaine is a common humectant (a substance that promotes retention of moisture). It's known to be gentle on the skin and can help balance hydration.

Niacinamide Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconGood for Minimizing Pores IconGood for Dark Spots IconHelps fight Acne IconHelps brighten skin Icon
NiacinamideNiacinamide Icon 6 Benefits

Niacinamide has emerged as an all-star ingredient due to its many benefits.

1,2-Hexanediol Skin Conditioning, Solvent

1,2-Hexanediol is a multi-tasker ingredient. It acts as a preservative to increase shelf-life and can aid other preservatives in preventing microbe growth. 1,2-Hexanediol also helps the skin retain moisture as a humectant.

Alcohol Denat. Antimicrobial, Astringent, Masking
Alcohol IconCan worsen Dry Skin IconMay worsen Oily Skin IconMay cause irritation IconMay worsen Eczema IconMay worsen Rosacea Icon
AlcoholAlcohol Icon 5 Concerns

Alcohol Denat. is an alcohol with a denaturant property. It is created by mixing ethanol with other additives.

Very Disliked Full details ->
Squalene Emollient, Skin Conditioning
Helps hydrate Dry Skin IconNot safe for Fungal Acne Icon
Helps hydrate Dry SkinHelps hydrate Dry Skin Icon Not safe for Fungal AcneNot safe for Fungal Acne Icon

Squalene is naturally found in plants and animals, including our skin and sebum. It is a lipid our bodies naturally produce and makes up about 10-12% of the oil on our skin. Our skin produces squalene to keep itself naturally hydrated.

Diethoxyethyl Succinate Solvent

We don't have a description for Diethoxyethyl Succinate.

Unknown Full details ->
Polyglyceryl-10 Stearate Skin Conditioning
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Polyglyceryl-10 Stearate is a skin conditioner with emollient and emulsifier properties.

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Sucrose Stearate Emollient, Emulsifying, Skin Conditioning
0 / 0

Sucrose Stearate is derived from stearic acid and sucrose (sugar). It is an emollient and emulsifier.

0 Com. / 0 Irr.
Very Disliked Full details ->
Polymethyl Methacrylate

We don't have a description for Polymethyl Methacrylate.

Disliked Full details ->
Polyglyceryl-10 Laurate Skin Conditioning
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Polyglyceryl-10 Laurate is an ester of lauric acid and Polyglycerin-10.

Very Disliked Full details ->
Phytosterols Skin Conditioning

We don't have a description for Phytosterols.

Caprylyl Methicone Skin Conditioning
Silicon Icon
SiliconSilicon Icon

Caprylyl Methicone is a type of silicone.

Very Disliked Full details ->
Carbomer Emulsion Stabilising, Gel Forming
1 / 0

Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.

1 Com. / 0 Irr.
Disliked Full details ->
Hydrogenated Lecithin Emulsifying, Skin Conditioning

Hydrogenated Lecithin is created from the hydrogenation of lecithin. Hydrogenation is a chemical reaction between molecule hydrogen and another element.

Hydrogenated Phosphatidylcholine Emulsifying, Skin Conditioning

We don't have a description for Hydrogenated Phosphatidylcholine.

Unknown Full details ->
Tromethamine Buffering, Masking

Tromethamine is an aliphatic compound. An aliphatic compound is an organic compound with open-chained carbon atoms. It is synthetically created. Tromethamine is used to balance pH and improve texture.

Ethylhexylglycerin Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

Xanthan Gum Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

Disliked Full details ->
Propanediol Solvent

Propanediol helps absorb ingredients into your skin, boosting their benefits. It can act as an emollient, making your skin softer. Propanediol can help products last longer by boosting the properties of preservatives within the formulation.

Cellulose Gum Emulsion Stabilising, Masking
0 / 0

Cellulose Gum is a water-soluble polymer that comes from cellulose. It is used to change the texture of a product and to help stabilize emulsions.

0 Com. / 0 Irr.
Disodium EDTA

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

Disliked Full details ->
Madecassoside Antioxidant, Skin Conditioning
Antioxidant IconHelps reduce irritation Icon
AntioxidantAntioxidant Icon Helps reduce irritationHelps reduce irritation Icon

Madecassoside comes from the super popular skin-soothing ingredient, Centella asiatica. It is one of four active compounds found in the extract of Centella Asiatica.

Beta-Glucan Skin Conditioning
Helps reduce Skin Redness Icon
Helps reduce Skin RednessHelps reduce Skin Redness Icon

Beta-Glucan is a polysaccharide. It can be derived from the cell walls of seaweed, oats, yeast, and fungi.

Tocopherol Antioxidant, Masking, Skin Conditioning
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin IconMay cause irritation Icon
Vitamin EVitamin E Icon AntioxidantAntioxidant Icon 4 Benefits May cause irritationMay cause irritation Icon

Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.

0-3 Com. / 0-3 Irr.
Onion Newpair B5 Ampoule
Allium Cepa Bulb Extract Skin Conditioning

Red onion extract? This ingredient not only benefits our diet but also offers numerous benefits for the skin.

Panthenol Skin Conditioning
0 / 0 Helps reduce irritation Icon
Helps reduce irritationHelps reduce irritation Icon

Panthenol is a common ingredient that helps hydrate and soothe the skin. It can be found naturally in our skin and hair.

0 Com. / 0 Irr.
1,2-Hexanediol Skin Conditioning, Solvent

1,2-Hexanediol is a multi-tasker ingredient. It acts as a preservative to increase shelf-life and can aid other preservatives in preventing microbe growth. 1,2-Hexanediol also helps the skin retain moisture as a humectant.

Niacinamide Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconGood for Minimizing Pores IconGood for Dark Spots IconHelps fight Acne IconHelps brighten skin Icon
NiacinamideNiacinamide Icon 6 Benefits

Niacinamide has emerged as an all-star ingredient due to its many benefits.

Trehalose Humectant, Moisturising

Trehalose is a disaccharide made of two glucose molecules (glucose is sugar!). Trehalose is used to help moisturize skin. It also has antioxidant properties.

Betaine Humectant, Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon
3 Benefits

Betaine is a common humectant (a substance that promotes retention of moisture). It's known to be gentle on the skin and can help balance hydration.

Acrylates Copolymer

Acrylates Copolymer is used as a film-forming agent and texture enhancer.

Disliked Full details ->
Arginine Masking, Skin Conditioning
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Arginine is an amino acid that is important for human development. Your body uses is it to produce hair keratin and skin collagen.

Butylene Glycol Humectant, Masking, Skin Conditioning
1 / 0

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

1 Com. / 0 Irr.
Caprylyl Glycol Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Allantoin Skin Conditioning, Skin Protecting, Soothing
0 / 0 Helps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon
3 Benefits

Allantoin plays a role in soothing and moisturizing the skin. Because of this, it is often added to products with strong active ingredients.

0 Com. / 0 Irr.
Pentylene Glycol Skin Conditioning, Solvent

Pentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.

Hydroxyacetophenone Antioxidant
Antioxidant Icon
AntioxidantAntioxidant Icon

Hydroxyacetophenone is antioxidant and helps with skin conditioning.

Caffeine Skin Conditioning

Caffeine is most associated with coffee, tea, and cacao. In skincare, it helps with calming inflammation and anti-aging.

Acetyl Glucosamine Skin Conditioning
Vitamin C Icon
Vitamin CVitamin C Icon

Acetyl Glucosamine is an antioxidant and humectant. It is a form of Vitamin C.

Melia Azadirachta Flower Extract Skin Conditioning

Melia Azadirachta Flower Extract is from the Neem tree. Neem trees originate from India.

Adenosine Skin Conditioning
Helps with Anti-Aging IconGood for Scar Healing Icon
2 Benefits

Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Ammonium Acryloyldimethyltaurate/Vp Copolymer (let's call it AAVC for short) is a synthetically created polymer. It's used as a film-forming agent and used to thicken the consistency of products.

Disliked Full details ->
Coccinia Indica Fruit Extract Skin Conditioning

We don't have a description for Coccinia Indica Fruit Extract.

Disodium EDTA

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

Disliked Full details ->
Tranexamic Acid Astringent, Skin Conditioning
Good for Dark Spots Icon
Good for Dark SpotsGood for Dark Spots Icon

Tranexamic Acid is best used for treating hyperpigmentation, discoloration, and melasma. It can also help build a stronger skin barrier.

Sodium Hyaluronate Humectant, Skin Conditioning
0 / 0 Hyaluronic Acid Icon
Hyaluronic AcidHyaluronic Acid Icon

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

0 Com. / 0 Irr.
Hydrolyzed Hyaluronic Acid Humectant, Skin Conditioning
Hyaluronic Acid Icon
Hyaluronic AcidHyaluronic Acid Icon

Hydrolyzed Hyaluronic Acid is a form of hyaluronic acid. It is created by the hydrolysis of hyaluronic acid with a high molecular weight. Once created, Hydrolyzed Hyaluronic Acid has a low molecular weight.

Sodium Acetylated Hyaluronate Humectant
Hyaluronic Acid Icon
Hyaluronic AcidHyaluronic Acid Icon

Sodium Acetylated Hyaluronate is a type of Hyaluronic Acid.

Ferulic Acid Antimicrobial, Antioxidant
Antioxidant IconHelps with Anti-Aging Icon
AntioxidantAntioxidant Icon Helps with Anti-AgingHelps with Anti-Aging Icon

Ferulic Acid is a plant based antioxidant. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells. Ferulic Acid can help reduce the formation of fine lines and hyperpigmentation.

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent
Loved

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Humectant, Masking, Skin Conditioning
Mixed

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

  • It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
  • It is a humectant, which means that it helps attract moisture into the skin.
  • It helps improve product application.

Overall, Butylene Glycol is a safe and well-rounded ingredient. It is unlikely to irritate skin, and works well with pretty much all other ingredients.

Humectant, Skin Conditioning
Loved

Betaine is a common humectant (a substance that promotes retention of moisture). It's known to be gentle on the skin and can help balance hydration.

Betaine is best for improving hydration and soothing irritated skin. Studies show betaine may help with uneven skin tones.

Betaine is naturally created in the skin and body. The form found within cosmetic products can be either plant-dervied or synthetic.

Learn more about Betaine
Smoothing
Loved

Niacinamide has emerged as an all-star ingredient due to its many benefits.

It is known to treat acne by reducing inflammation. It also helps fade dark-spots and strengthen the skin by promoting the growth of the ceramide barrier.

Other benefits include smoothing wrinkles and minimizing redness.

The cherry on top? Niacinamide can also help build keratin, a protein that keeps skin firm.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

Niacinamide can be mixed with other ingredients to boost benefits. For instance, it has shown to be effective when used with copper, folic acid, and zinc to treat acne.

Learn more about Niacinamide
Skin Conditioning, Solvent
Mixed

1,2-Hexanediol is a multi-tasker ingredient. It acts as a preservative to increase shelf-life and can aid other preservatives in preventing microbe growth. 1,2-Hexanediol also helps the skin retain moisture as a humectant.

In products that are water-based, this ingredient can help stabilize perfumes and fragrances. It can also help make the texture of products softer and more smooth.

Disliked

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.

Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.

Learn more about Disodium EDTA

Ingredient Ratings

Here's what our community thinks of the ingredients in these two products.

A-Cica 365 Blemish Calming Serum
12
4
10
2
liked
mixed
disliked
not rated
Onion Newpair B5 Ampoule
19
4
3
liked
mixed
disliked
not rated

When to use

4 Routines
50% use in am
50% use in pm
100% use every day
43 Routines
58% use in am
42% use in pm
86% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

Aestura A-Cica 365 Blemish Calming Serum 28 ingredients

A-Cica 365 Blemish Calming Serum hasn't been rated yet.
Rate it now

Isntree Onion Newpair B5 Ampoule 26 ingredients

5.0 /5
from 2 ratings