Paula's Choice CellularYouth Longevity Serum
A serum with 40 ingredients, including exfoliants and peptides.
Overview
What it is
Serum with 40 ingredients that contains exfoliants and peptides
Cool Features
It is cruelty-free and reef safe
Suited For
It has ingredients that are good for dry skin, brightening skin, sensitive skin, scar healing and better texture
Free From
It doesn't contain any harsh alcohols, common allergens, fragrances, parabens or sulfates
Fun facts
Paula's Choice is from United States.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside
Ingredients List
Water
Skin ConditioningPropanediol
SolventGlycerin
HumectantTriheptanoin
Skin ConditioningMethyl Gluceth-20
HumectantSimmondsia Chinensis Seed Oil
EmollientTridecyl Trimellitate
EmollientMaltodextrin
Absorbent1,2-Hexanediol
Skin ConditioningDimethicone
EmollientTaurine
BufferingBacillus Ferment
Skin ConditioningGanoderma Lucidum Stem Extract
Skin ConditioningHelianthus Annuus Sprout Extract
Skin ConditioningLycium Barbarum Fruit Extract
AstringentAcetyl Tetrapeptide-2
Skin ConditioningIsomalt
HumectantCoco-Caprylate/Caprate
EmollientHydroxyacetophenone
AntioxidantHydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingC9-12 Alkane
SolventDilinoleic Acid/Butanediol Copolymer
Glyceryl Behenate
EmollientPolyglyceryl-6 Octastearate
EmulsifyingSodium Phytate
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingPotassium Chloride
Acacia Senegal Gum
MaskingXanthan Gum
EmulsifyingPolysorbate 60
EmulsifyingSorbitan Isostearate
EmulsifyingSynthetic Fluorphlogopite
Caprylyl Glycol
EmollientCitric Acid
BufferingCastor Oil/Ipdi Copolymer
Lecithin
EmollientCyanocobalamin
Skin ConditioningTin Oxide
AbrasiveCI 77491
Cosmetic ColorantCI 77891
Cosmetic ColorantWater, Propanediol, Glycerin, Triheptanoin, Methyl Gluceth-20, Simmondsia Chinensis Seed Oil, Tridecyl Trimellitate, Maltodextrin, 1,2-Hexanediol, Dimethicone, Taurine, Bacillus Ferment, Ganoderma Lucidum Stem Extract, Helianthus Annuus Sprout Extract, Lycium Barbarum Fruit Extract, Acetyl Tetrapeptide-2, Isomalt, Coco-Caprylate/Caprate, Hydroxyacetophenone, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, C9-12 Alkane, Dilinoleic Acid/Butanediol Copolymer, Glyceryl Behenate, Polyglyceryl-6 Octastearate, Sodium Phytate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Potassium Chloride, Acacia Senegal Gum, Xanthan Gum, Polysorbate 60, Sorbitan Isostearate, Synthetic Fluorphlogopite, Caprylyl Glycol, Citric Acid, Castor Oil/Ipdi Copolymer, Lecithin, Cyanocobalamin, Tin Oxide, CI 77491, CI 77891
Key Ingredients
Benefits
Concerns
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterPropanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.ย
Itโs often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Learn more about PropanediolGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinWe don't have a description for Triheptanoin yet.
Methyl Gluceth-20 is a humectant. Humectants help draw moisture from the air to your skin.
It is created by combining polyethylene glycol with glucose.
This oil comes from the seeds of the desert shrub called Jojoba. It is more commonly known as jojoba oil, a non-comedogenic oil.
Jojoba oil does not contain fragrance and has many fatty-acids, making it a great soothing ingredient.
It also contains Vitamin E, a great moisturizing ingredient. Vitamin E is also an antioxidant and protects your skin against oxidative damage.
This ingredient humectant properties, meaning it helps draw moisture from the air. This helps keep your skin hydrated.
While jojoba has antibacterial properties, it is only able to kill some strains of bacteria.
Studies also show it helps in wound healing. In fact, Indigenous cultures have used jojoba as a moisturizer and to help treat burns for centuries.
Fun fact: Jojoba oil similar to natural human skin sebum, so it has a great effect on dry skin. It is also promising with helping to regulate sebum production.
Due to its fatty acid content, Jojoba oil may not be fungal acne safe. We recommend speaking with a professional if you have any concerns.
Learn more about Simmondsia Chinensis Seed OilTridecyl Trimellitate is a synthetic ingredient with emollient and skin conditioning properties. It also acts as a texture enhancer and helps products spread easily without feeling greasy.
As an emollient, it forms a light layer on the skin that keeps moisture in and improves water resistance. This is why you'll often find this ingredient in eye creams and other rich treatments.
This ingredient is seen as the elegant alternative to mineral oil.
Learn more about Tridecyl TrimellitateMaltodextrin is a polysaccharide. It is derived from starch such as rice, corn, wheat, or potato starch.
In food, Maltodextrin is used to improve the texture and thicken a product. Due to its structure, it can help create a gel texture. As an emulsion stabilizer, it helps keep the ingredients in a product together.
As a polysaccharide, Maltodextrin has moisturizing properties. Polysaccharides are a type of carbohydrate. The top layer of skin uses polysaccharides to retain water, keeping the skin hydrated.
Maltodextrin is water soluble and has a sweet taste.
Learn more about Maltodextrin1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.ย
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservativesย
Dimethicone is a type of synthetic silicone created from natural materials such as quartz.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Learn more about DimethiconeWe don't have a description for Taurine yet.
Bacillus Ferment is created by fermenting Bacillus bacteria with yeast extract and carbohydrates. It acts as a humectant and, depending on the strain, can also provide gentle enzymatic exfoliation.
Depending on the strain and formulation, it may also act as a peptide, probiotic, or prebiotic. Certain strains of Bacillus Ferment help support the skinโs microbiome, soothe inflammation, and promote barrier repair and hydration.
Itโs typically used at 0.5-5% concentration, either for mild exfoliation or to improve overall skin health and texture.
Some studies show that Bacillus species can inhibit certain plant fungi (such as Fusarium verticillioides and Fusarium oxysporum) used in agricultural biocontrol. However, these are filamentous molds, not the yeast (Malassezia furfur) responsible for fungal acne.
At this time, there are no studies showing that Bacillus Ferment inhibits Malassezia or that it has been tested on human skin or in cosmetic formulations. Because of this lack of cosmetic and dermatological research, we list Bacillus Ferment as not safe for fungal acne as a precaution. However, it may not trigger breakouts for everyone.
Learn more about Bacillus FermentThis ingredient is the stem of the Reishi mushroom.
The Reishi mushroom has antioxidant, anti-inflammatory, and antimicrobial properties.
This is due to its content of terpenoids, polysaccharides, macronutrients, and phenolic acids.
Learn more about Ganoderma Lucidum Stem ExtractWe don't have a description for Helianthus Annuus Sprout Extract yet.
Lycium Barbarum Fruit Extract comes from the Goji Berry. Goji berries are native to China and can be found across Eurasia.
Goji berries contain polysaccharides, carotenoids and flavonoids. Antioxidants help your body fight off free-radical molecules. These molecules are unstable and may damage your skin. By making free-radicals more stable, antioxidants can help with anti-aging.
Polysaccharides help hydrate the top layer of skin due to its ability to mimic natural carbohydrates.
Learn more about Lycium Barbarum Fruit ExtractThis peptide is more commonly known as Thymulen 4 BG.
It is derived from a youth hormone called thymopoietin. Thymopoietin helps regulate the immune system and decreases naturally with age.
According to the manufacturer, this peptide boosts the skin's immune defenses and regenerates the outer layers of skin.
Learn more about Acetyl Tetrapeptide-2We don't have a description for Isomalt yet.
Coco-Caprylate/Caprate is created from fatty coconut alcohol, caprylic acid, and capric acid.
It is a lightweight emollient. Emollients create a thin barrier on the skin to trap moisture in. This helps keep your skin hydrated and soft.
Once applied, Coco-Caprylate/Caprate is absorbed quickly and leaves a silky feel.
Coco-Caprylate/Caprate may not be fungal acne safe.
Learn more about Coco-Caprylate/CaprateHydroxyacetophenone is antioxidant with skin conditioning and soothing properties. It also boosts the efficiency of preservatives.
This ingredient is not irritating or sensitizing.
This is a synthetic polymer. It helps improve the texture of products by adding thickness and gel-like feel.
It is also an emulsifer, meaning it prevents ingredients such as oil and water from separating. It also helps evenly disperse other ingredients.
C9-12 Alkane is synethically created using alkanes, or paraffins. It is added to products as a solvent. This means its main purpose is to help dissolve ingredients and create even texture.
We don't have a description for Dilinoleic Acid/Butanediol Copolymer yet.
Glyceryl Behenate is a fatty acid created from glycerin and behenic acid. It is an emollient and emulsifier.
This ingredient may not be Malassezia folliculitis, or fungal acne safe.
We don't have a description for Polyglyceryl-6 Octastearate yet.
Sodium Phytate is the synthetic salt form of phytic acid. Phytic acid is an antioxidant and can be found in plant seeds.
Sodium Phytate is a chelating agent. Chelating agents help prevent metals from binding to water. This helps stabilize the ingredients and the product.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken and improve the texture of products. Due to its properties, it can prevent water and oil ingredients from separating.
Potassium Chloride can be bad for oily skin and be bad for acne prone skin.
Acacia Senegal Gum has skin soothing, thickening, and formulation stabilizing properties. It comes from the Acacia tree that is native to sub-Saharan Africa.
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumPolysorbate 60 is used to help stabilize products. It is a surfactant and emulsifier. These properties help keep ingredients together in a product. Surfactants help reduce surface tension between ingredients with different states, such as liquids and solids. Emulsifiers help prevent oils and waters from separating.
Polysorbate 60 is sorbitol-based and created from the ethoxylation of sorbitan. Ethoxylation is a chemical reaction used to add ethylene oxide. Sorbitan is a the dehydrated version of sorbitol, a sugar found in fruits.
In this case, the 60 comes from reacting 60 units of ethylene oxide with sorbitan.
Polysorbates are commonly used in medicine and foods.
Learn more about Polysorbate 60Sorbitan Isostearate is an emulsifer and cleaning agent. It is created from isostearic acid and sorbitol.
As an emulsifier, Sorbitan Isostearate prevents oils and water from separating.
Due to its isostearic acid base, it may not be safe for Malassezia or fungal acne.
Learn more about Sorbitan IsostearateSynthetic Fluorphlogopite is the synthethic version of mica. It consists of fluorine, aluminum and silicate.
Synthetic Fluorphlogopite is used to add volume to products.
It is considered non-irritating on the skin.
Learn more about Synthetic FluorphlogopiteCaprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.
It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.
Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.
This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.
Learn more about Caprylyl GlycolCitric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
In skincare formulas, citric acid can:
While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
Read more about some other popular AHA's here:
Learn more about Citric AcidCastor Oil/Ipdi Copolymer is an oil and isn't fungal acne safe.
Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of mixture of phospholipids.
This ingredient has emollient and emulsifying properties.
As an emollient, lecithen helps soften the skin and creates a barrier to keep moisture in.
As an emulsifier, it also helps prevent water and oil ingredients from separating. Lecithin can also help ingredients be better absorbed by the skin.
This is because the phospholipids in lecithin produce liposomes. Liposomes help other ingredients get through the skin barrier.
Depending on the source of this ingredient, lecithin may not be fungal acne safe. This is because some sources of lecithin come from soybean oil, which may feed the malassezia yeast that feeds fungal acne.
We recommend reaching out to the brand you are purchasing from to inquire about the source of their lecithin.
Some other names for this ingredient include soy lecithin and deoiled soy lecithin.
Learn more about LecithinCyanocobalamin is the manufactured version of vitamin B12. It has skin soothing, antioxidant, and barrier protecting properties. Topical cyanocobalamin is used to treat skin irritation and atopic dermatitis.
Tin Oxide is an inorganic oxide used to add opacity and volume to a product. In nature, it is already found in mineral form. The main ore of tin is an opaque and shiny mineral called casseterite.
Tin Oxide helps remove translucency in a product, or make it more opaque. Besides adding opacity, tin oxide is used for bulking to add volume.
Ci 77491 is also hydrated iron III oxide. It's sole purpose is to give a red/pink hue to products.
Iron III oxides are classified as inorganic chemicals for coloring.
Synthetically created Ci 77491 is considered safer than those naturally found. This is because the synthetically created version may contain less impurities. Iron oxides are generally non-toxic and non-allergenic.
Learn more about CI 77491Ci 77891 is a white pigment from Titanium dioxide. It is naturally found in minerals such as rutile and ilmenite.
It's main function is to add a white color to cosmetics. It can also be mixed with other colors to create different shades.
Ci 77891 is commonly found in sunscreens due to its ability to block UV rays.
Learn more about CI 77891Reviews
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Where it's from
Paula's Choice is a American brand
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about usยท Updated December 2, 2025 • Added by anemone