Mesoestetic Skin Balance Serum
A highly rated serum with 32 ingredients, including vitamin C, vitamin E, and peptides.
Overview
What it is
Serum with 32 ingredients that contains peptides, Vitamin C and Vitamin E
Cool Features
It is cruelty-free and reef safe
Suited For
It has ingredients that are good for anti aging, dry skin, brightening skin, sensitive skin, scar healing, dark spots and better texture
Free From
It doesn't contain any harsh alcohols, common allergens, oils, parabens, silicones or sulfates
Fun facts
Mesoestetic is from Spain. This product is used in 5 routines created by our community.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside
Ingredients List
Water
Skin ConditioningGlycerin
HumectantPentylene Glycol
Skin ConditioningPropanediol
Solvent1,2-Hexanediol
Skin ConditioningAloe Barbadensis Leaf Juice
Skin ConditioningRhodosorus Marinus Extract
AntioxidantChamomilla Recutita Extract
Skin ConditioningTephrosia Purpurea Seed Extract
Skin ConditioningCrocus Sativus Flower Extract
MaskingCalendula Officinalis Flower Extract
MaskingAcetyl Heptapeptide-4
HumectantAcetyl Tetrapeptide-2
Skin ConditioningPanthenol
Skin ConditioningTocopherol
AntioxidantAscorbyl Palmitate
AntioxidantFerulic Acid
AntimicrobialAscorbic Acid
AntioxidantPropylene Glycol
HumectantCaprylic/Capric Triglyceride
MaskingPEG-8
HumectantIsohexadecane
EmollientGlyceryl Polyacrylate
Acrylamide/Sodium Acryloyldimethyltaurate Copolymer
Emulsion StabilisingDehydroxanthan Gum
Emulsion StabilisingPolysorbate 80
EmulsifyingSorbitan Oleate
EmulsifyingCaprylyl Glycol
EmollientDisodium EDTA
Citric Acid
BufferingPotassium Sorbate
PreservativeSodium Benzoate
MaskingWater, Glycerin, Pentylene Glycol, Propanediol, 1,2-Hexanediol, Aloe Barbadensis Leaf Juice, Rhodosorus Marinus Extract, Chamomilla Recutita Extract, Tephrosia Purpurea Seed Extract, Crocus Sativus Flower Extract, Calendula Officinalis Flower Extract, Acetyl Heptapeptide-4, Acetyl Tetrapeptide-2, Panthenol, Tocopherol, Ascorbyl Palmitate, Ferulic Acid, Ascorbic Acid, Propylene Glycol, Caprylic/Capric Triglyceride, PEG-8, Isohexadecane, Glyceryl Polyacrylate, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Dehydroxanthan Gum, Polysorbate 80, Sorbitan Oleate, Caprylyl Glycol, Disodium EDTA, Citric Acid, Potassium Sorbate, Sodium Benzoate
Key Ingredients
Benefits
Concerns
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinPentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.
The hydrophilic trait of Pentylene Glycol makes it a humectant. As a humectant, Pentylene Glycol helps draw moisture from the air to your skin. This can help keep your skin hydrated.
This property also makes Pentylene Glycol a great texture enhancer. It can also help thicken or stabilize a product.
Pentylene Glycol also acts as a mild preservative and helps to keep a product microbe-free.
Some people may experience mild eye and skin irritation from Pentylene Glycol. We always recommend speaking with a professional about using this ingredient in your routine.
Pentylene Glycol has a low molecular weight and is part of the 1,2-glycol family.
Learn more about Pentylene GlycolPropanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.Â
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Learn more about Propanediol1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.Â
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservativesÂ
Aloe Barbadensis Leaf Juice comes from leaves of the aloe plant. Aloe Barbadensis Leaf Juice is best known for helping to soothe sunburns. It is also anti-inflammatory, moisturizing, antiseptic, and can help heal wounds.
Aloe is packed with good stuff including Vitamins A, C, and E. These vitamins are antioxidants, which help fight free-radicals and the damage they may cause. Free-radicals are molecules that may damage your skin cells, such as pollution.
Aloe Barbadensis Leaf Juice also contains sugars. These sugars come in the form of monosaccharides and polysaccharides, folic acid, and choline. These sugars are able to help bind moisture to skin.
It also contains minerals such as calcium, 12 anthraquinones, fatty acids, amino acids, and Vitamin B12.
Learn more about Aloe Barbadensis Leaf JuiceRhodosorus Marinus Extract is an antioxidant.
This ingredient comes from the Chamomile flower.
Chamomile is rich in antioxidants and has anti-inflammatory properties. Several compounds found in chamomile help with soothing, such as bisbolol.
Antioxidant components in chamomile help fight free-radical molecules. These unstable molecules may damage your skin cells. By stabilizing them, antioxidants may help reduce the signs of aging.
Ancient Greeks, Romans, and Egyptians used Chamomile to treat skin redness and dryness. Chamomile has also been used to help with stomach issues.
Learn more about Chamomilla Recutita ExtractWe don't have a description for Tephrosia Purpurea Seed Extract yet.
We don't have a description for Crocus Sativus Flower Extract yet.
Calendula Officinalis Flower Extract comes from the common Marigold plant part of the Asteraceae family. This ingredient is a skin conditioner.
Marigolds contain flavonoids. Flavonoids are a group of substances found naturally in plants. They possess antioxidant and inflammation properties.
This ingredient soothes skin inflammation by inhibiting inhibiting a part of the inflammation process.
Marigolds have been used in traditional medicine throughout Asia and Europe.
Learn more about Calendula Officinalis Flower ExtractAcetyl Heptapeptide-4 is a peptide with hydrating properties.
According to a manufacturer, a combination of this ingredient and caprylyl glycol strengthens the skin barrier by keeping your skin's natural biome in balance.
This peptide is more commonly known as Thymulen 4 BG.
It is derived from a youth hormone called thymopoietin. Thymopoietin helps regulate the immune system and decreases naturally with age.
According to the manufacturer, this peptide boosts the skin's immune defenses and regenerates the outer layers of skin.
Learn more about Acetyl Tetrapeptide-2Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Learn more about PanthenolTocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.
Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.
Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.
You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.
There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.
Learn more about TocopherolAscorbyl Palmitate is a fat-soluble form of vitamin C (Ascorbic Acid) made by combining it with palmitic acid.
It is able to blend easily into creams and oil-based formulas because it dissolves in oils rather than water.
As you may know, regular vitamin C is notorious for breaking down when exposed to sunlight and air. Ascorbyl Palmitate is more stable and degrades at a slower rate.
Research on whether it converts efficiently into active vitamin C once it's applied on your skin is still limited. Some in-vitro studies suggest it may support collagen production, but it is not considered one of the stronger vitamin C derivatives, like:
Due to the palmitic acid base, this ingredient may not be fungal acne safe. Comedogenic studies have also shown this ingredient to have a rating of 2.
It's also worth keeping in mind that comedogenic and irritancy ratings are tested on individual ingredients, not finished formulas. The final product's formulation, concentration, and other ingredients all play a role in how something actually behaves on your skin.
Learn more about Ascorbyl PalmitateFerulic Acid is a plant based antioxidant that can be naturally found in the cell walls of grains like rice, oats, and corn. It has antioxidant and antimicrobial properties, and has the ability to boost the performance of other antioxidants as well.
A well-known study found that adding Ferulic Acid to a solution of Vitamins C and E doubled the photoprotection of skin. This is why you'll often see it paired with Vitamin C or Vitamin E serums rather than sold on its own.
A 2025 review of 18 human studies found that using Ferulic Acid (0.5-1%) daily for one to three months showed improvements in:
As far as allergies go, Ferulic acid is generally well-tolerated but can cause an allergic reaction in very rare cases. It's also worth noting that Ferulic acid is often extracted from plant sources like rice bran or wheat bran, so be sure to path test if you have known grain allergies.
Outside of skincare, researchers are also looking into Ferulic Acid for its potential benefits in areas like diabetes, Alzheimer's, and heart health.
Learn more about Ferulic AcidAscorbic Acid is is pure Vitamin C and is the biologically active form used directly by skin.
Not only is vitamin C great for your overall health and immune system, but it also has plenty of benefits for your skin. It is best supported by academic literature for:
Topical vitamin C has been shown to help neutralize oxidative stress from UV and pollution, helping to improve photoaging and hyperpigmentation when used consistently.
One clinical study found that using 5% topical vitamin C for six months improved signs of photodamaged skin, both on the surface and in the deeper structural layers of the skin.
While vitamin C doesn’t replace sunscreen, studies show it can boost photoprotection when combined with Vitamin E and ferulic acid. These two ingredients help improve stability and protective effects.
The big downside of this ingredient is formulation difficulty. Vitamin C is prone to oxidation and doesn't penetrate the skin unless formulated correctly. Research found that vitamin C absorbs into the skin best at a low pH (< 3.5) with about 20% being the upper limit for effective absorption.
Skin levels can saturate after repeated application; this means your skin won’t keep absorbing more once it’s full of vitamin C. This is why more isn’t always better with vitamin C and why very high concentrations don’t necessarily give extra benefits.
Ascorbic acid generally works well with many skincare ingredients but can be irritating when combined with other active ingredients. Strong oxidizing acne treatments like benzoyl peroxide can reduce the effectiveness of vitamin C if they are used at the same time; they are often recommended for use at different times of day.
Read more about other types of Vitamin C:
Foods rich with vitamin C include oranges, strawberries, broccoli, bell peppers, and more. When consuming Vitamin C, your skin receives a portion of the nutrients.
Learn more about Ascorbic AcidPropylene Glycol is a synthetic, colorless, odorless liquid that has been a staple in cosmetics for decades. It is a skin conditioning agent, humectant, and solvent.
As a humectant, it draw water to the skin to reduce flaking and restore suppleness. It's also a solvent that helps dissolve other actives and keeps formulas stable across temperature changes.
The CIR Expert Panel has confirmed this ingredient to be nontoxic and clinical studies show no sensitization at cosmetic use concentrations.
True allergic reactions are quite rare: a 15-year retrospective study of 6,751 patients found only 0.31% had a positive reaction (and less than half were considered clinically relevant).
It seemed that when sensitization does occur, it's most commonly linked to topical medication (like corticosteroids) and not cosmetics. Allergic contact dermatitis also appears largely limited to individuals with underlying skin conditions.
Overall, propylene glycol is a well-studied ingredient that most people can tolerate without issue.
Learn more about Propylene GlycolThis ingredient is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.
It helps thicken a product's formula and makes it easier to spread by dissolving clumping compounds.
Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid. Though it behaves like an oil, it is not technically one due to its chemical composition. It is very stable, resistant to oxidation, and unlikely to go rancid. In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Be sure to patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
Learn more about Caprylic/Capric TriglyceridePEG-8 is a synthetic polymer used as a humectant and solvent.
This ingredient is able to help dissolve active ingredients, including water. This gives it humectant properties.
It is soluble in water. The number '8' stands for the molecular weight of the ingredient.
Learn more about PEG-8Isohexadecane is added to enhance texture, emulsify, and to help cleanse. It is an isoparrafin. It is a component of petrolatum.
Due to its large size, Isohexadecane is not absorbed by the skin. Instead, it sits on top and acts as an emollient. Emollients help keep your skin soft and smooth by trapping moisture within.
Isohexadecane is often used in products designed to help oily skin. It is lightweight and non-greasy while helping to moisturize. When mixed with silicones, it gives a product a silky feel.
Learn more about IsohexadecaneWe don't have a description for Glyceryl Polyacrylate yet.
This ingredient is a synthetic polymer used to stabilize formulas and give products a "gel-cream" feel.
When applied, this ingredient mostly stays on the surface of skin. Safety reviews have found these polymers safe in cosmetics when made to proper quality standards. Testing also shows they’re unlikely to cause irritation or sensitization at normal use levels.
We don't have a description for Dehydroxanthan Gum yet.
Polysorbate 80 is a surfactant and emulsifier. It is used to keep ingredients together, and prevent oils and waters from separating.
It is made from polyethoxylated sorbitan and oleic acid. This ingredient can be found in cosmetics, foods, and medicine. It is water-soluble.
Polysorbate 80 may not be fungal acne safe.
Learn more about Polysorbate 80Sorbitan Oleate is created from compounds in oleic acid and sorbitol.
It is used to stabilize a product by preventing ingredients from separating. Emulsifiers help keep ingredients together, such as oils and water.
According to a manufacturer, the ingredient Sorbitan Monooleate shares an INCI name with this one.
Sorbitan Oleate may not be fungal acne safe. It can also worsen oily skin.
Learn more about Sorbitan OleateCaprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid or alcohol, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Learn more about Caprylyl GlycolDisodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Learn more about Disodium EDTACitric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
In skincare formulas, citric acid can:
While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
Read more about some other popular AHA's here:
Learn more about Citric AcidPotassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.
This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.
Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.
You'll often find this ingredient used with other preservatives.
Learn more about Potassium SorbateSodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.
Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.
Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.
It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.
Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.
We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.
Learn more about Sodium BenzoateReviews
Where it's from
Mesoestetic is a Spanish brand
Often compared with
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about us· Updated September 8, 2025 • Added by Bibiwantstoglow