Anillo Rosy Night Repair Hair Essence
A hair serum with 37 ingredients, including ceramides and peptides.
Overview
What it is
Hair serum with 37 ingredients that contains ceramides and peptides
Cool Features
It is cruelty-free and reef safe
Suited For
It has ingredients that are good for anti aging, dry skin, sensitive skin, oily skin, scar healing, dark spots and better texture
Free From
It doesn't contain any harsh alcohols, parabens or sulfates
Fun facts
Anillo is from South Korea. This product is used in 8 routines created by our community.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside
Ingredients List
Cyclopentasiloxane
EmollientIsododecane
EmollientDimethiconol
EmollientC11-13 Isoparaffin
SolventCyclohexasiloxane
EmollientParfum
MaskingLinalool
PerfumingHydroxycitronellal
PerfumingLimonene
PerfumingEclipta Prostrata Extract
Skin ConditioningAlpha-Isomethyl Ionone
PerfumingCitronellol
PerfumingGeraniol
PerfumingCoumarin
PerfumingMelia Azadirachta Leaf Extract
Skin ConditioningCitral
PerfumingCaprylic/Capric Triglyceride
MaskingMoringa Oleifera Seed Oil
EmollientCamellia Japonica Seed Oil
EmollientWater
Skin ConditioningArgania Spinosa Kernel Oil
EmollientEuterpe Oleracea Fruit Oil
Skin ConditioningGossypium Herbaceum Seed Oil
Skin ConditioningHippophae Rhamnoides Oil
EmollientPrunus Persica Kernel Oil
EmollientGlycerin
HumectantRosa Canina Fruit Oil
Emollient1,2-Hexanediol
Skin ConditioningRosa Damascena Extract
MaskingAllantoin
Skin ConditioningPanthenol
Skin ConditioningCopper Tripeptide-1
Skin ConditioningAcetyl Hexapeptide-8
HumectantPalmitoyl Pentapeptide-4
Skin ConditioningPalmitoyl Tetrapeptide-7
Skin ConditioningPalmitoyl Tripeptide-1
Skin ConditioningCeramide NP
Skin ConditioningCyclopentasiloxane, Isododecane, Dimethiconol, C11-13 Isoparaffin, Cyclohexasiloxane, Parfum, Linalool, Hydroxycitronellal, Limonene, Eclipta Prostrata Extract, Alpha-Isomethyl Ionone, Citronellol, Geraniol, Coumarin, Melia Azadirachta Leaf Extract, Citral, Caprylic/Capric Triglyceride, Moringa Oleifera Seed Oil, Camellia Japonica Seed Oil, Water, Argania Spinosa Kernel Oil, Euterpe Oleracea Fruit Oil, Gossypium Herbaceum Seed Oil, Hippophae Rhamnoides Oil, Prunus Persica Kernel Oil, Glycerin, Rosa Canina Fruit Oil, 1,2-Hexanediol, Rosa Damascena Extract, Allantoin, Panthenol, Copper Tripeptide-1, Acetyl Hexapeptide-8, Palmitoyl Pentapeptide-4, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Ceramide NP
Key Ingredients
Benefits
Concerns
Ingredients Explained
Cyclopentasiloxane (D5) is a lightweight silicone that mostly acts as an emollient and solvent in cosmetics. Its the reason your products feel silky, fast-spreading, and non-greasy.
Since D5 is volatile, it does its thing and then evaporates off the skin quickly.
The safety profile of this ingredient is reassuring; the US CIR Expert Panel concluded D5 is safe as used in cosmetics and Health Canada concluded that D5 is not harmful to human health or the environment as currently used in cosmetics
There's a study that people mention about D5 in a rat study showing tumors. This study is related to long-term inhalation of high D5 levels.
Regulatory bodies have judged this study to be not applicable in topical skincare since skin absorption of D5 is very low and we're not really inhaling huge amounts of D5.
The only restriction for this ingredient is environmental. The European Chemicals Agency (ECHA) restricted D5 in wash-off cosmetics at or above 0.1% due to their persistence in water.
Learn more about CyclopentasiloxaneIsododecane is a fragrance, emollient, and solvent.
As an emollient, it helps your skin stay soft and hydrated. Emollients help trap moisture into your skin.
Isododecane's role as a solvent makes it a great texture enhancer. It spreads smoothly on skin and does not leave a sticky feeling behind. Isododecane also helps prevent color transfer in makeup products.
Isododecane is not absorbed into skin.
The chemical name for this ingredient is 2,2,4,6,6-PENTAMETHYLHEPTANE.
Learn more about IsododecaneDimethiconol is a silicone that resembles the popular dimethicone. Like other silicones, it is an emollient. Emollients create a thin film on skin to prevent moisture from escaping.
This ingredient helps to create a silky texture and improve spreadability. Due to its high molecular weight and thickness, it is often combined with cyclopentasiloxane.
C11-13 Isoparaffin can be bad for oily skin.
Cyclohexasiloxane is a type of silicone more commonly known as D6. It is an emollient and solvent.
Cyclohexasiloxane is used to evenly distribute ingredients throughout the product. When applied to the skin, Cyclohexasiloxane evaporates and leaves behind a silky feel.
As an emollient, it can help the skin feel soft and hydrated. It is also used to reduce frizz in hair products.
Learn more about CyclohexasiloxaneParfum is a catch-all term for an ingredient or more that is used to give a scent to products.
Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.
For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.
The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.
For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.
One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.
Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.
Parfum can also be used to mask or cover an unpleasant scent.
The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.
Learn more about ParfumLinalool is a fragrance and helps add scent to products. It's derived from common plants such as cinnamon, mint, citrus, and lavender.
Like Limonene, this ingredient oxidizes when exposed to air. Oxidized linalool can cause allergies and skin sensitivity.
This ingredient has a scent that is floral, spicy tropical, and citrus-like.
Learn more about LinaloolHydroxycitronellal is a fragrance created from citronellal. The smell of hydroxycitronellal is often described as "citrus-like" or "melon-like".
Hydroxycitronellal is a known EU allergen and may cause irritation when applied to the skin.
Limonene is a fragrance that adds scent and taste to a formulation.
It's found in the peel oil of citrus fruits and other plants such as lavender and eucalyptus. The scent of limonene is generally described as "sweet citrus".
Limonene acts as an antioxidant, meaning it helps neutralize free radicals.
When exposed to air, oxidized limonene may sensitize the skin. Because of this, limonene is often avoided by people with sensitive skin.
The term 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term. For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance.
Learn more about LimoneneThis ingredient is also known as Bhringaraj extract or False Daisy. It is a skin conditioning ingredient that keeps skin soft and hydrated.
Research shows it has antioxidant properties; lab studies have found it can protect skin cells from UV-induced damage and help suppress inflammation.
There's also some interesting research on its potential to support hair growth by promoting the growth phase of the hair cycle.
Those with an allergy to plants in the daisy family may want to patch test this ingredient. This ingredient is generally well-tolerated otherwise.
Learn more about Eclipta Prostrata ExtractAlpha-Isomethyl Ionone is a fragrance. It can be synthetically created or naturally occurring.
The scent of Alpha-Isomethyl Ionone is described as "flowery" but can also be "woody".
Naturally occurring Alpha-Isomethyl Ionone may be found in Saccharomyces cerevisiae, or the yeast used to make wine and bread.
The term 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term. For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance.
Learn more about Alpha-Isomethyl IononeCitronellol is used to add fragrance/parfum to a product. It is often derived from plants such as roses. In fact, it can be found in many essential oils including geranium, lavender, neroli, and more. The scent of Citronellol is often described as "fresh, grassy, and citrus-like".
Since the Citronellol molecule is already unstable, Citronellol becomes irritating on the skin when exposed to air.
Citronellol is a modified terpene. Terpenes are unsaturated hydrocarbons found in plants. They make up the primary part of essential oils.
Citronellol is not able to be absorbed into deeper layers of the skin. It has low permeability,
Citronellol is also a natural insect repellent.
Learn more about CitronellolGeraniol is used to add fragrance/parfum to a product. It is the main component of citronellol. It is a monoterpenoid and an alcohol.
Monoterpenes are naturally found in many parts of different plants.
Geraniol can be found in many essential oils including Rose Oil and Citronella Oil. The scent of Geraniol is often described as "rose-like". Many foods also contain Geraniol for fruit flavoring.
Geraniol can irritate the skin when exposed to air. However, irritation depends on the ability of geraniol to penetrate into the skin. In general, geraniol is not able to penetrate skin easily.
Geraniol is colorless and has low water-solubility. However, it is soluble in common organic solvents.
Like citronellol, it is a natural insect repellent.
2,6-Octadien-1-ol, 3,7-dimethyl-, (2E)-
Learn more about GeraniolCoumarins are a group of substances found naturally in plants. There are over 1300 types of coumarins identified. It has a natural vanilla scent.
Coumarin is an identified EU known allergy, meaning it may cause an allergic reaction when applied to the skin.
In many countries, coumarin is banned as a food additive. However, it can be found in soaps, tobacco products, and some alcohol drinks.
Plants use coumarins as a chemical defense. Some plants that have coumarins include lavender, tonka beans, and yellow clovers.
Learn more about CoumarinMelia Azadirachta Leaf Extract is extract from the neem plant.
The leaves of this tree contain flavonoids and polyphenols. These two compounds are antioxidants, anti-inflammatory, and antibacterial. Further research is needed as to their effects when applied on skin.
Citral is the molecule responsible for the fresh lemon scent in lemon, lime, and lemongrass. It is a fragrance ingredient that can be created from plant essential oils or synthetically.
Though Citral has documented antimicrobial activity against acne bacteria (which is where the marketing claims about it being good for acne-prone skin originate), real formulas use it at fragrance-level concentrations under 1% so there's likely no skin benefit.
You should know this ingredient is a known EU fragrance allergen.
Animal studies classifies this ingredient as a weak-to-moderate skin sensitizer and clinical patch testing on eczema patients confirmed it to be both a contact allergen and irritant.
The term 'citral' is a collective term for two geometric isomers: geranial/Citral A and neral/Citral B.
The term 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term. For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance.
Learn more about CitralCaprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.
Learn more about Caprylic/Capric TriglycerideMoringa Oleifera Seed Oil is a lightweight oil from the seeds of the Moringa oleifera tree. In cosmetics, it's an emollient that forms a light film to slow water loss and soften skin.
Its fatty acid composition is dominated by oleic acid (70-78%), with smaller amounts of behenic, palmitic, and stearic acids (this profile is actually pretty similar to olive oil).
Notably, this ingredient is oxidatively stable for an oil and resists going rancid as fast as other oils.
A small, in vivo study on 32 participants found a cream with this ingredient increased skin hydration with no reported skin irritation. It also found the tocopherol content gave it some antioxidant activity as well.
One thing to flag for fungal acne:
Because this oil is so high in oleic acid, Malassezia can use it as a food source and this ingredient may not be fungal acne safe.
For everyone else, this ingredient is well-tolerated and nourishing with a good safety track record.
Learn more about Moringa Oleifera Seed OilCamellia Japonica Seed Oil comes from the Japanese Camellia plant. This plant is native to East Asia and known as "Tsubaki" in Japanese.
Camellia Japonica Seed Oil is rich in oleic acid. This makes it a great emollient. Emollients help soften and soothe the skin by forming a barrier. This barrier traps moisture within, keeping your skin hydated.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterYou may know this ingredient as argan oil. It has emollient and skin conditioning properties that help soften skin and reinforce the lipid barrier.
The fatty acid profile of argan oil is roughly 45-55% oleic acid, 28-36% linoleic acid, 10-15% palmitic acid, and 5-7% stearic acid. It also contains vitamin E, sterols, squalene, and polyphenols like ferulic acid.
Two clinical studies in postmenopausal women found that applying argan oil for 60 days significantly improved skin elasticity and moisturization (reduced transepidermal water loss and increased epidermal water content).
Since it is high in oleic and linoleic acid, this ingredient may not be fungal acne safe. Both of these fall in the C11-C24 range that Malassezia yeast can metabolize.
Learn more about Argania Spinosa Kernel OilAcai oil is extracted from the pulp of the acai palm fruit. It is rich in phenolic compounds and fatty acids like oleic and palmitic acid.
Due to the presence of fatty acids, this ingredient may not be Malassezia folliculitis safe.
This plant is native to the Amazon rainforest.
Learn more about Euterpe Oleracea Fruit OilGossypium Herbaceum Seed Oil is AKA cotton seed oil.
Cotton seed oil is rich in omega-6 fatty acids. The majority of these fatty acids include linoleic (~54%) and oleic (~19%). It is structurally similar to sunflower seed oil.
When used in cosmetics, this ingredient is refined and purified to remove toxins naturally found in the plant.
This ingredient may not be fungal-acne safe due to the fatty acid content.
Learn more about Gossypium Herbaceum Seed OilHippophae Rhamnoides Oil also known as seabuckthorn oil. This oil is usually extracted from the fruit pulp or seeds.
Seabuckthorn is rich in phytosterols, carotenoids, Vitamins A, C, and E. This gives it strong antioxidant properties that can help soothe and protect your skin from oxidative damage.
This oil is rich in fatty acids, including: two types of linoleic acid (~30-34%), oleic acid (17%), and palmiteic acid (35%). Note these numbers are averages, and different parts of the plant will vary.
Palmitoleic acid has been shown to help soothe inflammation and promote wound healing. It is also naturally found in the fat of our skin.
Overall, seabuckthorn oil is great for nourishing, hydrating, and soothing skin. While it shows UV protecting properties, it should not replace sunscreen.
Due to the rich fatty acid content, this ingredient may not be Malassezia folliculitis, or fungal acne, safe.
Seabuckthorn berries are little orange fruits. This plant is native to Asia.
Learn more about Hippophae Rhamnoides OilPrunus Persica Kernel Oil is oil expressed from the kernel of the peach. Peach Kernel oil has antioxidant and moisturizing properties.
Peach kernel oil is rich in fatty acids. The main fatty acids include oleic and linoleic acid.
As an emollient, peach kernel oil helps moisturize and soften you skin. Emollients help trap moisture in by creating a film on top of the skin. This keeps your skin hydrated.
Learn more about Prunus Persica Kernel OilGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinRosa Canina Fruit Oil is a non-fragrant plant oil that has earned its skincare reputation through chemistry.
It's dominated by fatty acids like linoleic acid (~35-55%), alpha-linolenic acid (~17-27%), and oleic acid (~14-22%). This is the exact profile that supports skin barrier, locks in hydration, and calms inflammation.
A 2024 review found evidence for the Rosa canina species supports its use for scarring, hyperpigmentation, wrinkles, and atopic dermatitis; this was mostly credited to its vitamin C content and fatty acid composition as the primary active mechanisms.
You might see this ingredient marketed as a "natural retinol". Some rosehip seed oils contains traces of all-trans-retinoic acid but these trace amounts are far below biologically active levels.
The Cosmetic Ingredient Review Panel has deemed this ingredient safe and it's well-tolerated.
Fungal acne: The fatty acids of this oil fall into the C11-24 range that Malassezia yeast can metabolize, so this ingredient may not be fungal acne safe.
Learn more about Rosa Canina Fruit Oil1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
Rosa Damascena Extract comes from the Damask rose.
The Damask Roses' petals have been found to help sooth skin. The petals also contain antioxidant compounds.
Rosa Damascena Extract is a tonic. Tonics are used to remove soap residues. They also help moisturize the skin.
Learn more about Rosa Damascena ExtractAllantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.
Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.
Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.
It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.
Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.
This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.
Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.
Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.
Learn more about AllantoinPanthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Learn more about PanthenolCopper Tripeptide-1 (GHK-Cu) is a skin repairing ingredient known for its ability to boost collagen, improve firmness, and support skin regeneration.
It is a complex made up of a naturally occurring peptide (glycine-histidine-lysine) and copper, an essential trace element.
While studying wound healing, researchers noticed GHK-Cu stimulated hair follicle enlargement and growth by keeping hair in its active growth phase longer. This has made it a promising ingredient for hair regrowth treatments.
Some people have reported increased facial hair. While GHK-Cu can make your hair follicles bigger, it usually doesn’t turn soft, barely-visible facial hairs into thick, dark ones.
Anecdotal reports suggest that overusing copper peptides might lead to premature aging due to excess free copper or enzyme imbalances. This claim isn’t backed by large-scale studies.
Unfortunately, there are limited human studies for this ingredient. While early results are promising, many studies are either small, in-vitro, or not rigorously controlled.
For example, there is a 1998 study that explored the effects of copper tripeptide, vitamin C, tretinoin, and melatonin on skin repair and collagen synthesis.
After one month, increased procollagen production was seen in 7 out of 10 participants using copper tripeptide (more than those using vitamin C, melatonin, or tretinoin.
While the study was exploratory, it offers early evidence that copper tripeptide may support collagen production. Larger, well-designed trials are still needed to confirm its potential and understand individual responses.
Read more about other common types of peptides here:
Learn more about Copper Tripeptide-1Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative".
It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time.
The comparison to Botox does have limits because the molecule is water-loving and relatively large.
Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles.
So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging.
A 12 week human study of a multi-ingredient regimen containing this ingredient saw:
While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone).
Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations.
Learn more about Acetyl Hexapeptide-8You might know this ingredient as Matrixyl. It is a synthetic peptide made up of five amino acids attached to a palmitic acid, a fatty acid that helps it absorb into skin more easily.
As a signal peptide, Matrixyl acts like a little messenger. Once it reaches your skin cells, it tells them to ramp up production of collagen, elastin, and other proteins that keep skin looking firm and smooth.
A 12 week clinical study found that a moisturizer containing just 3 ppm of Matrixyl led to a significant improvement in fine-lines and wrinkles. Another study showed an 18% reduction in wrinkle depth, 37% reduction in wrinkle thickness, and a 21% improvement in skin firmness after just 28 days of twice-daily use.
The coolest part is that it works at incredibly low concentrations (like 0.0003%) and it plays well with other actives.
The CIR (Cosmetic Ingredient Review) panel found it to be non-sensitizing across multiple tests and human patch tests also showed no irritation or sensitization.
Fun fact: Matrixyl was originally developed by French company Sederma and Procter & Gamble.
Read more about other common types of peptides here:
Learn more about Palmitoyl Pentapeptide-4Palmitoyl Tetrapeptide-7 (formerly Palmitoyl Tetrapeptide-3) is a synthetic peptide. Its main job is to fight what researchers call "inflammaging".
"Inflammaging" is the slow, low-grade chronic inflammation that quietly breaks down collagen as we age.
This ingredient calms down a specific inflammation signal in your skin cells (called IL-6). When left unchecked, this signal triggers enzymes that break down collagen and elastin.
Clinical testing showed statistically significant improvements in:
Studies also found the more of this ingredient used, the more your skin produces Collagen I, fibronectin, and hyaluronic acid.
You'll likely see this ingredient paired with Palmitoyl Tripeptide-1 in the well-known Matrixyl 3000 complex for enhanced anti-aging effects.
A 3% concentration applied twice daily for two months showed meaningful skin rejuvenation results in clinical panels.
Fungal acne note:
Usually a palmitic acid component can feed Malassezia in unbound form, but here is is covalently bonded to the peptide. This means it is very difficult for Malassezia to access, and therefore very unlikely to cause fungal acne.
Palmitoyl Tripeptide-1 (aka Pal-GHK) is a synthetic signal peptide made of three amino acids attached to palmitic acid.
That fatty acid attachment is the key: it boosts the peptide's ability to penetrate the skin barrier. This puts it closer to the dermal cells where it can actually make a difference.
Once there, it acts as a matrikine, a signaling peptide that prompts fibroblasts to produce more collagen, fibronectin, and hyaluronic acid.
In vitro studies show it can boost collagen production in skin cells even when UV-damaged skin samples were treated with it at a tiny concentration (it almost fully restored dermal collagen at 5ppm). It achieved this at 100x lower concentration than retinoic acid, which needed 500 ppm to do the same thing.
Human clinical data is promising, but modest:
A study of 23 female volunteers found a small but statistically significant increase (~4%) in skin thickness after treatment at 4 ppm.
A separate small trial of 15 women showed statistically significant reductions in wrinkle length, depth, and skin roughness after applying it twice daily for four weeks.
You'll likely see Pal-GHK paired with Palmitoyl Tetrapeptide-7 as part of the Matrixyl 3000 complex.
Fungal acne note:
Usually a palmitic acid component can feed Malassezia in unbound form, but here is is covalently bonded to the peptide. This means it is very difficult for Malassezia to access, and therefore very unlikely to cause fungal acne.
Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.
Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.
This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.
A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.
Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.
Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.
Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.
Learn more about Ceramide NPReviews
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Where it's from
Anillo is a Korean brand
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about us· Published July 24, 2025 • Added by gcvjhkjvyuhjmn