This anti-aging ampoule is formulated around Collagen Extract and Niacinamide to soften the look of wrinkles and hydrate skin.
This anti-aging ampoule is formulated around Acetyl Hexapeptide-8 and Palmitoyl Pentapeptide-4 to soften the look of wrinkles and strengthen the skin barrier.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
No concerns
Ingredients Side-by-side
Collagen Extract
Skin Conditioning
Glycerin
Humectant
Butylene Glycol
Humectant
Niacinamide
Smoothing
Betaine
Humectant
Glycereth-26
Humectant
Acetyl Hexapeptide-8
Humectant
Copper Tripeptide-1
Skin Conditioning
Oligopeptide-29
Antioxidant
Oligopeptide-32
Antiseborrhoeic
Palmitoyl Pentapeptide-4
Skin Conditioning
Palmitoyl Tripeptide-1
Skin Conditioning
Palmitoyl Tetrapeptide-7
Skin Conditioning
Palmitoyl Tripeptide-5
Skin Conditioning
Octapeptide-7
Skin Protecting
Sh-Decapeptide-7
Antioxidant
Sh-Octapeptide-4
Antioxidant
Sh-Oligopeptide-9
Humectant
Sh-Pentapeptide-19
Skin Conditioning
Pentapeptide-18
Skin Conditioning
Acetyl Tetrapeptide-5
Humectant
Sh-Oligopeptide-1
Skin Conditioning
Sh-Oligopeptide-2
Skin Conditioning
Sh-Polypeptide-1
Skin Conditioning
Sh-Polypeptide-22
Skin Conditioning
Dipeptide Diaminobutyroyl Benzylamide Diacetate
Skin Conditioning
Hydrolyzed Elastin
EmollientHydrolyzed Collagen
Emollient
Sodium Hyaluronate
Humectant
Sodium Acetylated Hyaluronate
Humectant
Hydrolyzed Hyaluronic Acid
Humectant
Hydroxypropyltrimonium Hyaluronate
Sodium Hyaluronate Crosspolymer
Humectant
Hyaluronic Acid
Humectant
Potassium Hyaluronate
Skin ConditioningHydrolyzed Extensin
Skin ConditioningIsostearic Acid
Cleansing
Sucrose Stearate
EmollientPhytosteryl/Octyldodecyl Lauroyl Glutamate
Skin ConditioningOctyldodecanol
Emollient
Sodium Stearoyl Glutamate
Cleansing1,2-Hexanediol
Skin Conditioning
Ceramide NP
Skin Conditioning
Squalane
Emollient
Caprylic/Capric Glycerides
EmollientXylitylglucoside
Humectant
Anhydroxylitol
Humectant
Xylitol
Humectant
Water
Skin ConditioningDextrin
AbsorbentCyclodextrin
AbsorbentPentylene Glycol
Skin Conditioning
Cocos Nucifera Fruit Extract
Emollient
Pinus Sylvestris Leaf Extract
TonicPolyglyceryl-10 Laurate
Skin Conditioning
Propanediol
Solvent
Caprylyl Glycol
Emollient
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingCaprylic/Capric Triglyceride
Masking
Arginine
Masking
Chlorphenesin
Antimicrobial
Xanthan Gum
EmulsifyingAdenosine
Skin Conditioning
Sodium Polyacrylate
Absorbent
Disodium EDTA
Ethylhexylglycerin
Skin ConditioningCollagen Extract, Glycerin, Butylene Glycol, Niacinamide, Betaine, Glycereth-26, Acetyl Hexapeptide-8, Copper Tripeptide-1, Oligopeptide-29, Oligopeptide-32, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-5, Octapeptide-7, Sh-Decapeptide-7, Sh-Octapeptide-4, Sh-Oligopeptide-9, Sh-Pentapeptide-19, Pentapeptide-18, Acetyl Tetrapeptide-5, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-22, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Hydrolyzed Elastin, Hydrolyzed Collagen, Sodium Hyaluronate, Sodium Acetylated Hyaluronate, Hydrolyzed Hyaluronic Acid, Hydroxypropyltrimonium Hyaluronate, Sodium Hyaluronate Crosspolymer, Hyaluronic Acid, Potassium Hyaluronate, Hydrolyzed Extensin, Isostearic Acid, Sucrose Stearate, Phytosteryl/Octyldodecyl Lauroyl Glutamate, Octyldodecanol, Sodium Stearoyl Glutamate, 1,2-Hexanediol, Ceramide NP, Squalane, Caprylic/Capric Glycerides, Xylitylglucoside, Anhydroxylitol, Xylitol, Water, Dextrin, Cyclodextrin, Pentylene Glycol, Cocos Nucifera Fruit Extract, Pinus Sylvestris Leaf Extract, Polyglyceryl-10 Laurate, Propanediol, Caprylyl Glycol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Caprylic/Capric Triglyceride, Arginine, Chlorphenesin, Xanthan Gum, Adenosine, Sodium Polyacrylate, Disodium EDTA, Ethylhexylglycerin
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative".
It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time.
The comparison to Botox does have limits because the molecule is water-loving and relatively large.
Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles.
So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging.
A 12 week human study of a multi-ingredient regimen containing this ingredient saw:
While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone).
Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations.
Learn more about Acetyl Hexapeptide-8Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolCopper Tripeptide-1 (GHK-Cu) is a skin repairing ingredient known for its ability to boost collagen, improve firmness, and support skin regeneration.
It is a complex made up of a naturally occurring peptide (glycine-histidine-lysine) and copper, an essential trace element.
While studying wound healing, researchers noticed GHK-Cu stimulated hair follicle enlargement and growth by keeping hair in its active growth phase longer. This has made it a promising ingredient for hair regrowth treatments.
Some people have reported increased facial hair. While GHK-Cu can make your hair follicles bigger, it usually doesn’t turn soft, barely-visible facial hairs into thick, dark ones.
Anecdotal reports suggest that overusing copper peptides might lead to premature aging due to excess free copper or enzyme imbalances. This claim isn’t backed by large-scale studies.
Unfortunately, there are limited human studies for this ingredient. While early results are promising, many studies are either small, in-vitro, or not rigorously controlled.
For example, there is a 1998 study that explored the effects of copper tripeptide, vitamin C, tretinoin, and melatonin on skin repair and collagen synthesis.
After one month, increased procollagen production was seen in 7 out of 10 participants using copper tripeptide (more than those using vitamin C, melatonin, or tretinoin.
While the study was exploratory, it offers early evidence that copper tripeptide may support collagen production. Larger, well-designed trials are still needed to confirm its potential and understand individual responses.
Read more about other common types of peptides here:
Learn more about Copper Tripeptide-1You might know this ingredient as Matrixyl. It is a synthetic peptide made up of five amino acids attached to a palmitic acid, a fatty acid that helps it absorb into skin more easily.
As a signal peptide, Matrixyl acts like a little messenger. Once it reaches your skin cells, it tells them to ramp up production of collagen, elastin, and other proteins that keep skin looking firm and smooth.
A 12 week clinical study found that a moisturizer containing just 3 ppm of Matrixyl led to a significant improvement in fine-lines and wrinkles. Another study showed an 18% reduction in wrinkle depth, 37% reduction in wrinkle thickness, and a 21% improvement in skin firmness after just 28 days of twice-daily use.
The coolest part is that it works at incredibly low concentrations (like 0.0003%) and it plays well with other actives.
The CIR (Cosmetic Ingredient Review) panel found it to be non-sensitizing across multiple tests and human patch tests also showed no irritation or sensitization.
Fun fact: Matrixyl was originally developed by French company Sederma and Procter & Gamble.
Read more about other common types of peptides here:
Learn more about Palmitoyl Pentapeptide-4Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:
Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.
On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.
Typical use levels in a formula run about 1-5%.
Learn more about Pentylene GlycolWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water
