Factorefive Skincare Regenerative Serum Versus SkinMedica TNS® Advanced+ Serum
Updated on February 09, 2024
Overview
What they are
These products are both reef safe serums. They have a total of 8 ingredients in common
Cool Features
They both contain peptides
Suited For
They're both likely to be good for dry skin and brightening skin
Free From
They both do not contain any harsh alcohols, common allergens, oils, parabens or sulfates
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Factorefive Skincare Regenerative Serum 22 ingredients
SkinMedica TNS® Advanced+ Serum 35 ingredients
About this product
About this product
At a glance
Click on any of the items below to learn more
Factorefive Skincare Regenerative Serum 22 ingredients
SkinMedica TNS® Advanced+ Serum 35 ingredients
Key Ingredients
Benefits
Concerns
Key Ingredients
Benefits
Ingredients Side-by-side
Human Bone Marrow Stem Cell Conditioned Media
Skin ConditioningWater
Skin ConditioningAloe Barbadensis Leaf Juice
Skin Conditioning
Glycerin
Humectant
Niacinamide
Smoothing
Sodium Ascorbyl Phosphate
Antioxidant
PEG-8/Smdi Copolymer
Hydroxyethylcellulose
Emulsion StabilisingXanthan Gum
EmulsifyingPhenoxyethanol
Preservative
Acetyl Octapeptide-3
Humectant
Bis(Tripeptide-1) Copper Acetate
Skin Conditioning
Sodium Hyaluronate
Humectant
Lecithin
EmollientAcmella Oleracea Extract
Skin ProtectingPolysorbate 20
Emulsifying
Camellia Sinensis Leaf Extract
Antimicrobial
Ethylhexylglycerin
Skin ConditioningCitric Acid
Buffering
Disodium EDTA
Palmitoyl Tripeptide-37
Skin Conditioning
Parfum
Masking
Human Bone Marrow Stem Cell Conditioned Media, Water, Aloe Barbadensis Leaf Juice, Glycerin, Niacinamide, Sodium Ascorbyl Phosphate, PEG-8/Smdi Copolymer, Hydroxyethylcellulose, Xanthan Gum, Phenoxyethanol, Acetyl Octapeptide-3, Bis(Tripeptide-1) Copper Acetate, Sodium Hyaluronate, Lecithin, Acmella Oleracea Extract, Polysorbate 20, Camellia Sinensis Leaf Extract, Ethylhexylglycerin, Citric Acid, Disodium EDTA, Palmitoyl Tripeptide-37, Parfum
Water
Skin ConditioningPentylene Glycol
Skin ConditioningHuman Neonatal Fibroblast Conditioned Media
Skin ConditioningGlycereth-7 Triacetate
EmollientShea Butter Ethyl Esters
Emollient
Glycerin
Humectant
Ethoxydiglycol
HumectantLactococcus Ferment Lysate
Skin ConditioningWhey Protein
Skin ConditioningChlorella Vulgaris Extract
Skin ConditioningSaccharide Isomerate
HumectantTrifluoroacetyl Tripeptide-2
Skin Conditioning
Dimer Tripeptide-43
Hydrolyzed Linseed Extract
Skin ConditioningVitis Vinifera Flower Cell Extract
MaskingPyrus Malus Fruit Extract
Skin ConditioningHydroxyacetophenone
Antioxidant
Tocopheryl Acetate
Antioxidant
Propanediol
SolventXanthan Gum
EmulsifyingPolyacrylate Crosspolymer-6
Emulsion StabilisingPolyacrylate-13
Polyisobutene
Sclerotium Gum
Emulsion StabilisingPEG-12 Dimethicone
Skin Conditioning
Lecithin
EmollientPullulan
Butylene Glycol
Humectant
Sodium Citrate
BufferingPolysorbate 20
Emulsifying
Aminomethyl Propanol
BufferingDextran
Disodium EDTA
Phenoxyethanol
Preservative
Ethylhexylglycerin
Skin ConditioningWater, Pentylene Glycol, Human Neonatal Fibroblast Conditioned Media, Glycereth-7 Triacetate, Shea Butter Ethyl Esters, Glycerin, Ethoxydiglycol, Lactococcus Ferment Lysate, Whey Protein, Chlorella Vulgaris Extract, Saccharide Isomerate, Trifluoroacetyl Tripeptide-2, Dimer Tripeptide-43, Hydrolyzed Linseed Extract, Vitis Vinifera Flower Cell Extract, Pyrus Malus Fruit Extract, Hydroxyacetophenone, Tocopheryl Acetate, Propanediol, Xanthan Gum, Polyacrylate Crosspolymer-6, Polyacrylate-13, Polyisobutene, Sclerotium Gum, PEG-12 Dimethicone, Lecithin, Pullulan, Butylene Glycol, Sodium Citrate, Polysorbate 20, Aminomethyl Propanol, Dextran, Disodium EDTA, Phenoxyethanol, Ethylhexylglycerin
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumPhenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of mixture of phospholipids.
This ingredient has emollient and emulsifying properties.
As an emollient, lecithen helps soften the skin and creates a barrier to keep moisture in.
As an emulsifier, it also helps prevent water and oil ingredients from separating. Lecithin can also help ingredients be better absorbed by the skin.
This is because the phospholipids in lecithin produce liposomes. Liposomes help other ingredients get through the skin barrier.
Depending on the source of this ingredient, lecithin may not be fungal acne safe. This is because some sources of lecithin come from soybean oil, which may feed the malassezia yeast that feeds fungal acne.
We recommend reaching out to the brand you are purchasing from to inquire about the source of their lecithin.
Learn more about LecithinPolysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.
As a surfactant, it helps collect dirt and oils for washing. Emulsifiers prevent oils and water from separating.
Polysorbate 20 also adds scent to a product. Since it is made using sorbitol, it has a sweet scent. Sorbitol can also be found in fruits such as apples and peaches.
The lauric acid used to create Polysorbate 20 is often derived from coconuts.
Polysorbate 20 may not be fungal acne safe.
Learn more about Polysorbate 20Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.
Disodium EDTA plays a role in making products more stable by aiding other preservatives.
It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.
Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.
Learn more about Disodium EDTAIngredient Ratings
Here's what our community thinks of the ingredients in these products.
When to use
Factorefive Skincare Regenerative Serum 22 ingredients
SkinMedica TNS® Advanced+ Serum 35 ingredients
Reviews
Here's what our community thinks
Factorefive Skincare Regenerative Serum 22 ingredients
SkinMedica TNS® Advanced+ Serum 35 ingredients
Upon first try, I liked the glowy dewy effect it gave under my moisturizer and sunscreen. However, I can't help but notice that it pills quite badly. It wasn't returnable so I forced myself to use it and oh boy... If comedones popping up everywhere around my cheekbones and forehead by the first week wasn't bad enough, the pump started malfunction very soon. Actually baffling how popular this Show more
