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Factorefive Skincare Regenerative Serum Ingredients Explained

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Updated on February 09, 2024 Submitted by MelissaScott

Overview

What it is

Serum with 22 ingredients that contains hyaluronic acid, niacinamide, peptides and Vitamin C

Cool Features

It is reef safe

Suited For

It has ingredients that are good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture

Free From

It doesn't contain any harsh alcohols, common allergens, oils, parabens, silicones or sulfates

Fun facts

Factorefive Skincare is from United States. This product is used in 2 routines created by our community.

We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.

You should know

Here's our breakdown of the notable ingredients, benefits, and concerns we determined from the ingredients in this product. Click any item to learn more.

Notable Ingredients

Vitamin C
Niacinamide
Hyaluronic Acid
Peptides (3)

Benefits

Hydrating
Good For Oily Skin
Redness Reducing (4)
Reduces Irritation (2)
Skin Texture
Reduces Large Pores (2)
Anti-Aging (2)
Dark Spots (2)
Scar Healing
Acne Fighting (2)
Brightening (3)

Concerns

Rosacea
Eczema

Ingredient Info

Click any item below to learn more and view relevant ingredients.
alcohol-free
silicon-free
fragrance-free
sulfate-free
paraben-free
oil-free
fungal-acne safe
reef-safe
eu-allergen-free
vegan
cruelty-free

Ingredients Overview

Here's our quick-to-read summary of the ingredients in this product. Keep scrolling if you'd like to learn more about what each ingredient does!
Ingredient
Features
1
Antimicrobial, Antioxidant, Skin Conditioning
Antioxidant Icon
2
Skin Conditioning, Solvent
3
Skin Conditioning
Helps reduce Skin Redness IconHelps reduce irritation Icon
4
Humectant, Skin Conditioning, Skin Protecting, Solvent
0 / 0
Helps hydrate Dry Skin IconHelps brighten skin Icon
5
Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconGood for Minimizing Pores IconGood for Dark Spots IconHelps fight Acne IconHelps brighten skin Icon
6
Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps brighten skin Icon
7
8
Emulsion Stabilising, Stabilising
9
Emulsifying, Emulsion Stabilising, Gel Forming, Skin Conditioning
10
Preservative
Preservative Icon
11
Humectant, Skin Conditioning
Peptide Icon
12
Skin Conditioning
Peptide Icon
13
Humectant, Skin Conditioning
0 / 0
Hyaluronic Acid Icon
14
Emollient, Emulsifying, Skin Conditioning
15
Skin Protecting
16
Emulsifying
0 / 0
Not safe for Fungal Acne Icon
17
Antimicrobial, Antioxidant, Astringent, Emollient, Humectant, Masking, Skin Conditioning, Skin Protecting, Tonic
Antioxidant IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconHelps fight Acne Icon
18
Skin Conditioning
19
Buffering, Masking
AHA IconMay cause irritation IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconMay worsen Rosacea IconHelps brighten skin Icon
20
21
Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon
22
Masking, Perfuming
Fragrance IconMay worsen Eczema IconMay worsen Rosacea Icon

Ingredients Explained

This product contains 22 ingredients. Click on any ingredient to learn more about it
1
What it does: Antimicrobial, Antioxidant, Skin Conditioning

Human T Cell Conditioned Media is an antioxidant.

2
What it does: Skin Conditioning, Solvent
Community Rating: Loved

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. Talk about multi-purpose! If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
3
What it does: Skin Conditioning
Community Rating: Liked

Aloe Barbadensis Leaf Juice comes from leaves of the aloe plant. Aloe Barbadensis Leaf Juice is best known for helping to soothe sunburns. It is also anti-inflammatory, moisturizing, antiseptic, and can help heal wounds.

Aloe is packed with good stuff including Vitamins A, C, and E. These vitamins are antioxidants, which help fight free-radicals and the damage they may cause. Free-radicals are molecules that may damage your skin cells, such as pollution.

Aloe Barbadensis Leaf Juice also contains sugars. These sugars come in the form of monosaccharides and polysaccharides, folic acid, and choline. These sugars are able to help bind moisture to skin.

It also contains minerals such as calcium, 12 anthraquinones, fatty acids, amino acids, and Vitamin B12.

Learn more about Aloe Barbadensis Leaf Juice
4
What it does: Humectant, Skin Conditioning, Skin Protecting, Solvent
Community Rating: Loved

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
5
What it does: Smoothing
Community Rating: Loved

Niacinamide has emerged as an all-star ingredient due to its many benefits.

It is known to treat acne by reducing inflammation. It also helps fade dark-spots and strengthen the skin by promoting the growth of the ceramide barrier.

Other benefits include smoothing wrinkles and minimizing redness.

The cherry on top? Niacinamide can also help build keratin, a protein that keeps skin firm.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

Niacinamide can be mixed with other ingredients to boost benefits. For instance, it has shown to be effective when used with copper, folic acid, and zinc to treat acne.

Learn more about Niacinamide
6
What it does: Antioxidant
Community Rating: Liked

Sodium Ascorbyl Phosphate is a form of Vitamin C. It is the salt of ascorbic acid.

This ingredient is more gentle than ascorbic acid. It is also more stable when exposed to light and oxygen.

Vitamin C helps reduce redness, improve skin texture, reduce the effects of aging, reduce the visibility of dark spots, and brighten skin.

Your skin uses Vitamin C to produce collagen and collagen production plays a role in having a strong skin barrier and plump skin. As an antioxidant, this ingredient also helps reduce the signs of aging such as fine-lines and wrinkles.

VItamin C helps brighten skin by blocking the process of skin darkening.

In a 2011 study, Sodium Ascorbyl Phosphate was found to have antibacterial properties. This may help treat acne.

Read more about other types of Vitamin C:

Learn more about Sodium Ascorbyl Phosphate
7

We don't have a description for Peg-8/Smdi Copolymer.

8
What it does: Emulsion Stabilising, Stabilising
Community Rating: Mixed

Hydroxyethylcellulose is used to improve the texture of products. It is created from a chemical reaction involving ethylene oxide and alkali-cellulose. Cellulose is a sugar found in plant cell walls and help give plants structure.

Hydroxyethylcellulose helps stabilize products by preventing ingredients from separating. It can also help thicken the texture of a product.

This ingredient can also be found in pill medicines to help our bodies digest other ingredients.

Learn more about Hydroxyethylcellulose
9
What it does: Emulsifying, Emulsion Stabilising, Gel Forming, Skin Conditioning
Community Rating: Disliked

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Learn more about Xanthan Gum
10
What it does: Preservative
Community Rating: Very Disliked

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent germ and microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

11
What it does: Humectant, Skin Conditioning
Community Rating: Loved

Acetyl Octapeptide-3 is a synthetic peptide. It is often called a botox alternative due to its ability to restrict the movement of muscles, and thus reduce the appearance of fine-lines.

While this peptide can help reduce wrinkles and fine-lines, the research is lacking in it being as effective as botox.

All current studies for this ingredient are either from manufacturers or look at amounts far greater than in actual products.

Learn more about Acetyl Octapeptide-3
12
What it does: Skin Conditioning
Community Rating: Liked

Bis(Tripeptide-1) Copper Acetate is a peptide.

13
What it does: Humectant, Skin Conditioning
Community Rating: Loved

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Learn more about Sodium Hyaluronate
14
What it does: Emollient, Emulsifying, Skin Conditioning
Community Rating: Disliked

Lecithin is a term for a group of substances found in plants, animals, and humans. They are made up of mixture of fatty acids. These fatty acids usually are a mixture of phosphoric acid's choline ester connected to stearic, oleic, and palmitic acids. Most lecithins are created from plant ingredients scuh as sunflower.

Lecithin is an emollient. Emollients help soften the skin and creates a barrier to keep moisture in.

As an emulsifier, it also helps prevent water and oil ingredients from separating. Lecithin can help ingredients be better absorbed by the skin. The phospholipids in Lecithin can produce liposomes. Liposomes help other ingredients get through the skin barrier.

Learn more about Lecithin
15
What it does: Skin Protecting

We don't have a description for Acmella Oleracea Extract.

16
What it does: Emulsifying
Community Rating: Very Disliked

Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.

As a surfactant, it helps collect dirt and oils for washing. Emulsifiers prevent oils and water from separating.

Polysorbate 20 also adds scent to a product. Since it is made using sorbitol, it has a sweet scent. Sorbitol can also be found in fruits such as apples and peaches.

The lauric acid used to create Polysorbate 20 is often derived from coconuts.

Polysorbate 20 may not be fungal acne safe.

Learn more about Polysorbate 20
17
What it does: Antimicrobial, Antioxidant, Astringent, Emollient, Humectant, Masking, Skin Conditioning, Skin Protecting, Tonic
Community Rating: Loved

Camellia Sinensis Leaf Extract is derived from the leaves of the tea plant. Black tea, green tea, and oolong tea are all harvested from this plant.

Camellia Sinensis Leaf Extract has many benefits. It contains polyphenols, a strong antioxidant. Antioxidants help fight off free-radical molecules that damage skin cells. The antioxidants in green tea neutralize free-radicals from the sun. This gives the skin some extra UV protection, but should not replace sunscreen.

Many components of tea have anti-inflammatory properties. Polyphenols and L-theanine help soothe the skin and reduce irritation. L-theanine is an amino acid that makes up most of the amino acids found in tea leaves. The caffeine in Camellia Sinensis Leaf Extract helps calm inflamed blood vessels.

Camellia Sinensis Leaf Extract also contains Vitamin Bs, linoleic acid, magnesium, calcium, iron, and zinc.

Camellia Sinensis Leaf Extract also has antimicrobial properties.

Research has shown both drinking Camellia Sinensis Leaf Tea and applying it to the skin can help boost skin elasticity and hydration. Studies also show using tea extract may reduce sebum, or oil, production.

Learn more about Camellia Sinensis Leaf Extract
18
What it does: Skin Conditioning
Community Rating: Mixed

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.

19
What it does: Buffering, Masking
Community Rating: Disliked

Citric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).

If you spot Citric Acid near the end of an ingredient list, it's likely there as a pH adjuster rather than an active ingredient.

As an AHA, Citric Acid removes the top layer of skin cells from the newer layer of skin underneath. This helps skin to remove dark spots and look more even.

Read more about some other popular AHA's here:

Learn more about Citric Acid
20
What it does:
Community Rating: Disliked

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.

Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.

Learn more about Disodium EDTA
21
What it does: Skin Conditioning

Palmitoyl Tripeptide-37 isn't fungal acne safe and is a peptide.

22
What it does: Masking, Perfuming
Community Rating: Very Disliked

Parfum is a catch-all term for an ingredient or more that is used to give aroma to products. Parfum, or fragrance, can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "Parfum" in the ingredients list is a different mixture.

In the US, the alternative name for parfum is 'fragrance'. The term 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.

For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance. One example is Calendula flower extract. Essential oil ingredients still impart a scent or 'fragrance'.

Depending on the blend, it can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.

Products use parfum often to give products a scent or cover up smells of different ingredients.

The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.

Learn more about Parfum
Embed Ingredients

Here's what our community thinks of the 22 ingredients in this product ✨

41% are loved or liked
9% have mixed ratings
32% are disliked or very disliked
18% have no rating yet

When to use

Here's some more info on how this product is used by our community.

Directions

Shake before use. After cleansing, apply one pump of Regenerative Serum to face and neck, morning and night. For best results, use twice daily under your preferred FACTORFIVE moisturizer.

Shake before use. After cleansing, apply one pump of Regenerative Serum to face and neck, morning and night. For best results, use twice daily under your preferred FACTORFIVE moisturizer.

When to use

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